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The map label for this gene is gntK [H]

Identifier: 119385657

GI number: 119385657

Start: 95148

End: 95651

Strand: Direct

Name: gntK [H]

Synonym: Pden_2932

Alternate gene names: 119385657

Gene position: 95148-95651 (Clockwise)

Preceding gene: 119385656

Following gene: 119385664

Centisome position: 5.5

GC content: 70.24

Gene sequence:

>504_bases
GTGCAGCATATCGTGGTGATGGGCGTCTCGGGCGCCGGGAAAAGCACCACGGGCGAGGCGCTGGCCCGGCACCTGGGCTG
GCCCTTCGTCGAGGGCGACAGCTTTCACCCCGAGGCCAATGTCGCCAAGATGCGCGACGGCATTCCGCTGGACGACGGCG
ACCGCGAGCCCTGGCTGCGGGCGCTGGCCGCCGAGATCGCGCGGAACGAGGCGCGGGGCCAGTCCTCGGTCATGGGCTGT
TCGTCGCTGAAGCGGGCCTATCGCGACATCCTGCGCCAGGGGGCGCCGGTGGTGCGCTTCGTGCATGTGCATGGCTCGCG
CGCGTTGCTGGAAAGCCGGCTGTCGCATCGCGCGGGGCATTTCTTCCCGGCCAAGCTGCTGGATTCGCAGCTGGCGACGC
TGGAGCCGCTGGCACCTGACGAGGACGGCGTCGTGGTCGACATGGCCCTGTCGGTCGAGGATCAGTTGCACCAGGCCCTG
CGCCTGCTGGGGCTTGGGGGCTGA

Upstream 100 bases:

>100_bases
AAAAGACCACGCTGAAGACCTGGACGGTGATGGAGACGCTGCTGGGCACCATCGCCTTCGGTTTTGCGCTGCTTGGCTGG
TGGCTGCTGTGAAGGGCGTG

Downstream 100 bases:

>100_bases
AACGAAGCGAGCGCCGTGCCCGCGAAGCGGGGGGCGGCCTTGCCCGAAATGCCGGCCGCGGCAAAGCCGCGGGACGTGTC
GCGGGCAGGTGAGCCGACTT

Product: carbohydrate kinase

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MQHIVVMGVSGAGKSTTGEALARHLGWPFVEGDSFHPEANVAKMRDGIPLDDGDREPWLRALAAEIARNEARGQSSVMGC
SSLKRAYRDILRQGAPVVRFVHVHGSRALLESRLSHRAGHFFPAKLLDSQLATLEPLAPDEDGVVVDMALSVEDQLHQAL
RLLGLGG

Sequences:

>Translated_167_residues
MQHIVVMGVSGAGKSTTGEALARHLGWPFVEGDSFHPEANVAKMRDGIPLDDGDREPWLRALAAEIARNEARGQSSVMGC
SSLKRAYRDILRQGAPVVRFVHVHGSRALLESRLSHRAGHFFPAKLLDSQLATLEPLAPDEDGVVVDMALSVEDQLHQAL
RLLGLGG
>Mature_167_residues
MQHIVVMGVSGAGKSTTGEALARHLGWPFVEGDSFHPEANVAKMRDGIPLDDGDREPWLRALAAEIARNEARGQSSVMGC
SSLKRAYRDILRQGAPVVRFVHVHGSRALLESRLSHRAGHFFPAKLLDSQLATLEPLAPDEDGVVVDMALSVEDQLHQAL
RLLGLGG

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=180, Percent_Identity=41.6666666666667, Blast_Score=136, Evalue=8e-33,
Organism=Escherichia coli, GI87082265, Length=166, Percent_Identity=40.9638554216867, Blast_Score=129, Evalue=7e-32,
Organism=Escherichia coli, GI1790719, Length=163, Percent_Identity=41.1042944785276, Blast_Score=127, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI25146487, Length=163, Percent_Identity=46.6257668711656, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320454, Length=148, Percent_Identity=40.5405405405405, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 18062; Mature: 18062

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHIVVMGVSGAGKSTTGEALARHLGWPFVEGDSFHPEANVAKMRDGIPLDDGDREPWLR
CCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHH
ALAAEIARNEARGQSSVMGCSSLKRAYRDILRQGAPVVRFVHVHGSRALLESRLSHRAGH
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCC
FFPAKLLDSQLATLEPLAPDEDGVVVDMALSVEDQLHQALRLLGLGG
CCHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQHIVVMGVSGAGKSTTGEALARHLGWPFVEGDSFHPEANVAKMRDGIPLDDGDREPWLR
CCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHH
ALAAEIARNEARGQSSVMGCSSLKRAYRDILRQGAPVVRFVHVHGSRALLESRLSHRAGH
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCC
FFPAKLLDSQLATLEPLAPDEDGVVVDMALSVEDQLHQALRLLGLGG
CCHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]