Click here to switch to the map view.

The map label for this gene is ygcA [C]

Identifier: 119358501

GI number: 119358501

Start: 3127733

End: 3129163

Strand: Reverse

Name: ygcA [C]

Synonym: Cpha266_2737

Alternate gene names: 119358501

Gene position: 3129163-3127733 (Counterclockwise)

Preceding gene: 119358502

Following gene: 119358494

Centisome position: 99.85

GC content: 50.38

Gene sequence:

>1431_bases
ATGGAAAAAGAGCAGTACAGAAAAGGAGCGCTTATCGAGCTCAGCATTACCGATCTTGCCGAAAAGAACCAGTGCTTCGG
GCGACTTGATAACGGTATGGCCGTTATGGTTACAGGGATGCTTGCGGTCGGAGACCGGGTATCGGCAGCGATAAAAAAAA
TTCGGCAGCGATATATCGAAGCGACTCTCGTTGAGGTGCTGATTCCCTCGGGCGACAGGGTGACGCCTGAGTGCGGCTTT
TTTGGCGTTTGTGGAGGATGCAAGATGATGCATATCGCTTATGAGGTGCAGAAGGAGCTCAAGCGTAAAAAGATCATCGA
CGCCATGGTTCATATCGGAGGTTTCGAAAATCCTCAGGTCAAGCCGGTCATGGGCGCCGTCGCGCCATTACATTACCGCA
ACAAGATCGAGTTTTCCTTTTCCGCTCGTCGTTACCTCATGCCAGGGGAGCTTGTGCTTGAAAAGCCACTCTCTTCGCCG
GATTTTGCCCTTGGGTTCCATGCTCCGGGAAATTTTGAAAAAGTGCTCGATGTTGACTACTGTTATCTTGCGCCTTCGAG
CATGAATGAGGTTCTTGCCCTGACGCGCAGTTTTTGTCTTGAGCGCGAACTCAGCGCATACAGCACCAGATCGAATACGG
GTTATTTACGAAACCTTGTTATCAGATCCAGTGAACACCGTCGTCAACTCATGGTGAATCTGGTGACATCATGGCATGAC
AGTGAACTGATGAGAAGTTATGCTGAAGTTCTTTCCGCGGCCATGCCGAATCAGGAGATGACCATCCTGAATAATGTAAC
GACAAGAAAGAACACCGTCGCTCTCGGAGAAGAGGAGTTTCTTGTAGCCGGAGACGGGTTTATCACCGAAAGATTGGGGA
AACTGGATTTCAACATATCGGCGAACTCGTTTTTTCAAACCAATTCAGCGCAGACAGTTTTGCTTTACGACGAAATTCTG
AGGGTCGCCGGGCTCGACATCGGAGATACCGTTTATGATCTTTTCTGTGGAACAGGAACCATTGCGCTCTATCTTTCCGA
TTACTGCCGACAGGTGATAGGGCTTGAGGTTTCTGAAAGCTCGGTTGCCGATGCCCGAAAAAATGCGGCACTGAACCAGA
GAGAGCATGTTCTTTTCATGCAGGTTGACCTCAATGATCACAGAGCCATGGTTGATGCGCTTCAACGTCACGACAAACCC
CGGGTTATTGTGACCGACCCGCCAAGAGCAGGCATGCATCCAAAGGCGCTTGAGGTGATGGTGAGGATTGCTCCTGAAAA
AATCGTCTATGTCAGTTGCAACCCGGCAAGCCTTGCCCGTGACGGCAGCGAGATATGCAAGGGGGGATACCGGCTCACAT
CGCTCCAACCGGTTGATATGTTTCCGCATACCAGCCACATTGAAAGCGTTGCCTGTTTTGAGCGCGAGTGA

Upstream 100 bases:

>100_bases
ACACGGAACTCCGAATTCCTTTACTACAACCCGGTCTTGGCGACAGCGCAGGTGTTTTTGGTGCCGCGCTGTTGACTCAC
GGCAGATAATTGCATGGCCA

Downstream 100 bases:

>100_bases
TCAGGGTGTGGGGGGGTCGATTTCTGTATACTCAATAACTTCAGCACCGCTCTCTTTTGAACTCTCCCAGGCAAGAAATT
TTTCTATATCCTGACTGATA

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MEKEQYRKGALIELSITDLAEKNQCFGRLDNGMAVMVTGMLAVGDRVSAAIKKIRQRYIEATLVEVLIPSGDRVTPECGF
FGVCGGCKMMHIAYEVQKELKRKKIIDAMVHIGGFENPQVKPVMGAVAPLHYRNKIEFSFSARRYLMPGELVLEKPLSSP
DFALGFHAPGNFEKVLDVDYCYLAPSSMNEVLALTRSFCLERELSAYSTRSNTGYLRNLVIRSSEHRRQLMVNLVTSWHD
SELMRSYAEVLSAAMPNQEMTILNNVTTRKNTVALGEEEFLVAGDGFITERLGKLDFNISANSFFQTNSAQTVLLYDEIL
RVAGLDIGDTVYDLFCGTGTIALYLSDYCRQVIGLEVSESSVADARKNAALNQREHVLFMQVDLNDHRAMVDALQRHDKP
RVIVTDPPRAGMHPKALEVMVRIAPEKIVYVSCNPASLARDGSEICKGGYRLTSLQPVDMFPHTSHIESVACFERE

Sequences:

>Translated_476_residues
MEKEQYRKGALIELSITDLAEKNQCFGRLDNGMAVMVTGMLAVGDRVSAAIKKIRQRYIEATLVEVLIPSGDRVTPECGF
FGVCGGCKMMHIAYEVQKELKRKKIIDAMVHIGGFENPQVKPVMGAVAPLHYRNKIEFSFSARRYLMPGELVLEKPLSSP
DFALGFHAPGNFEKVLDVDYCYLAPSSMNEVLALTRSFCLERELSAYSTRSNTGYLRNLVIRSSEHRRQLMVNLVTSWHD
SELMRSYAEVLSAAMPNQEMTILNNVTTRKNTVALGEEEFLVAGDGFITERLGKLDFNISANSFFQTNSAQTVLLYDEIL
RVAGLDIGDTVYDLFCGTGTIALYLSDYCRQVIGLEVSESSVADARKNAALNQREHVLFMQVDLNDHRAMVDALQRHDKP
RVIVTDPPRAGMHPKALEVMVRIAPEKIVYVSCNPASLARDGSEICKGGYRLTSLQPVDMFPHTSHIESVACFERE
>Mature_476_residues
MEKEQYRKGALIELSITDLAEKNQCFGRLDNGMAVMVTGMLAVGDRVSAAIKKIRQRYIEATLVEVLIPSGDRVTPECGF
FGVCGGCKMMHIAYEVQKELKRKKIIDAMVHIGGFENPQVKPVMGAVAPLHYRNKIEFSFSARRYLMPGELVLEKPLSSP
DFALGFHAPGNFEKVLDVDYCYLAPSSMNEVLALTRSFCLERELSAYSTRSNTGYLRNLVIRSSEHRRQLMVNLVTSWHD
SELMRSYAEVLSAAMPNQEMTILNNVTTRKNTVALGEEEFLVAGDGFITERLGKLDFNISANSFFQTNSAQTVLLYDEIL
RVAGLDIGDTVYDLFCGTGTIALYLSDYCRQVIGLEVSESSVADARKNAALNQREHVLFMQVDLNDHRAMVDALQRHDKP
RVIVTDPPRAGMHPKALEVMVRIAPEKIVYVSCNPASLARDGSEICKGGYRLTSLQPVDMFPHTSHIESVACFERE

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=314, Percent_Identity=34.0764331210191, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI51173878, Length=314, Percent_Identity=34.0764331210191, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI269784678, Length=386, Percent_Identity=26.4248704663212, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI269784680, Length=207, Percent_Identity=31.4009661835749, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI269784676, Length=207, Percent_Identity=31.4009661835749, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI20149688, Length=207, Percent_Identity=31.4009661835749, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1789148, Length=475, Percent_Identity=28.2105263157895, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1787083, Length=399, Percent_Identity=26.5664160401003, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790403, Length=254, Percent_Identity=26.7716535433071, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71997438, Length=178, Percent_Identity=33.1460674157303, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322909, Length=394, Percent_Identity=26.6497461928934, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24666579, Length=435, Percent_Identity=28.735632183908, Blast_Score=137, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 53198; Mature: 53198

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50926 TRAM ; PS01231 TRMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKEQYRKGALIELSITDLAEKNQCFGRLDNGMAVMVTGMLAVGDRVSAAIKKIRQRYIE
CCHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEEHHHHHCHHHHHHHHHHHHHHHH
ATLVEVLIPSGDRVTPECGFFGVCGGCKMMHIAYEVQKELKRKKIIDAMVHIGGFENPQV
HHHHHHEECCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KPVMGAVAPLHYRNKIEFSFSARRYLMPGELVLEKPLSSPDFALGFHAPGNFEKVLDVDY
CHHHHHHCCHHCCCEEEEEECCCEEECCCHHHEECCCCCCCEEEEECCCCCCHHHEECEE
CYLAPSSMNEVLALTRSFCLERELSAYSTRSNTGYLRNLVIRSSEHRRQLMVNLVTSWHD
EEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCH
SELMRSYAEVLSAAMPNQEMTILNNVTTRKNTVALGEEEFLVAGDGFITERLGKLDFNIS
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCCEEEECCCHHHHHHCCEEEEEC
ANSFFQTNSAQTVLLYDEILRVAGLDIGDTVYDLFCGTGTIALYLSDYCRQVIGLEVSES
CCCEEECCCCCEEEEHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCH
SVADARKNAALNQREHVLFMQVDLNDHRAMVDALQRHDKPRVIVTDPPRAGMHPKALEVM
HHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHH
VRIAPEKIVYVSCNPASLARDGSEICKGGYRLTSLQPVDMFPHTSHIESVACFERE
HEECCCEEEEEECCHHHHHCCCHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MEKEQYRKGALIELSITDLAEKNQCFGRLDNGMAVMVTGMLAVGDRVSAAIKKIRQRYIE
CCHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEEHHHHHCHHHHHHHHHHHHHHHH
ATLVEVLIPSGDRVTPECGFFGVCGGCKMMHIAYEVQKELKRKKIIDAMVHIGGFENPQV
HHHHHHEECCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KPVMGAVAPLHYRNKIEFSFSARRYLMPGELVLEKPLSSPDFALGFHAPGNFEKVLDVDY
CHHHHHHCCHHCCCEEEEEECCCEEECCCHHHEECCCCCCCEEEEECCCCCCHHHEECEE
CYLAPSSMNEVLALTRSFCLERELSAYSTRSNTGYLRNLVIRSSEHRRQLMVNLVTSWHD
EEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCH
SELMRSYAEVLSAAMPNQEMTILNNVTTRKNTVALGEEEFLVAGDGFITERLGKLDFNIS
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCCEEEECCCHHHHHHCCEEEEEC
ANSFFQTNSAQTVLLYDEILRVAGLDIGDTVYDLFCGTGTIALYLSDYCRQVIGLEVSES
CCCEEECCCCCEEEEHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCH
SVADARKNAALNQREHVLFMQVDLNDHRAMVDALQRHDKPRVIVTDPPRAGMHPKALEVM
HHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHH
VRIAPEKIVYVSCNPASLARDGSEICKGGYRLTSLQPVDMFPHTSHIESVACFERE
HEECCCEEEEEECCHHHHHCCCHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]