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The map label for this gene is pgk

Identifier: 119358498

GI number: 119358498

Start: 3125165

End: 3126358

Strand: Direct

Name: pgk

Synonym: Cpha266_2734

Alternate gene names: 119358498

Gene position: 3125165-3126358 (Clockwise)

Preceding gene: 119358497

Following gene: 119358499

Centisome position: 99.72

GC content: 50.92

Gene sequence:

>1194_bases
ATGCAGAAAAAGACCTTGTCTGACGTAGCAATCCAAGGCAAACGGGTATTAATGCGCGTCGATTTTAATGTCCCTATCGA
TGAAGAAAAAAATATCACCGATGACAAAAGAATCGTTGAGGCCCTTCCTTCCATAAAAAAAATCATCGACGGGGGTGGGC
GCCTGATTCTCATGTCCCATCTGGGCAGGCCAAAAGGAAAGGTGAATGCCGAGTTTTCGCTTGCTCCTGTTGCGCACAGA
CTTTCGGAACTTCTTGATACTCCCGTTGCCATGGCTAAAGACTGCATCGGCACGGAAGTCATGCAGGCGGCTCTCGCTCT
TCAGGACGGCGAAGTGATGCTTCTTGAAAATCTCAGATTTCACGCCGAAGAGGAGGCCAACAACCCGGATTTCGCAAAAG
AGCTTGCTTCGCTTGGAGAGATTTTTGTGAACGATGCGTTTGGAACTGCCCACAGAGCCCATGCGTCGACAGAGGGAATT
ACCCATTATGTCCCCGTAGCGGTTGCCGGCTATCTTATCGAAAAGGAACTGAACTATCTTGGGAAAGCTCTTGACAACCC
CGAAAGACCTTTTGTGGCAATTCTCGGCGGATCGAAAATATCCGGCAAGATCGATGTGCTTGAAAATCTCTTTACAAAAG
TCGATACGGTGCTCATAGGCGGAGCCATGGTGTTTACCTTTTTCAAGGCTCAGGGGCTCAATGTCGGAAACTCCCTGGTT
GAAGACAACAAACTCGACCTTGCTCAGGCGCTGCTCAAACAGGCCGCCGATAAGGGAATCAACCTCCTTCTTCCGGACGA
TGTTCTGGTGGCTGCGACTATTTCTTCCGACGCGTCTTCGCATGTTGAGGCGGTCAACAGCATGAGCGACGGGATGATCG
GTGTTGATATCGGCCCGAAAACCATCGAAAAATACCGGAATGAAATTCTTGCCGCCCGCACCGTGCTGTGGAACGGTCCT
ATGGGAGTTTTTGAAATCGACAACTTTGCCGAGGGAACATTCGCCATTGCGAAAGCTCTTGCCGAAGCGACCTCCTCCGG
GGCAATAACCATTGTGGGGGGGGGCGATTCTGCTGCCGCTATCGCTAAAGCAGCGCTTTCGGACTCTATCACCCATATTT
CAACGGGCGGAGGAGCGAGTCTTGAATTTCTCGAGGGGAAAGCGCTTCCCGGAATCGAAGCACTGAACGATTAA

Upstream 100 bases:

>100_bases
TCCTTGAGGAATAGCTCAACGGGGTGTAAGCCGTTCCTTGAAATAATTTATATTATCACCATATACATAAACGATTTTCT
CTAACTAACCTTACGTTACA

Downstream 100 bases:

>100_bases
AGAGTACCGAGGATTATGGGTATGTCTACAGAAAAGATCGATTACTCCCTTTACGCTTTCGGGATGCCAGAGAGCCGCAA
AGTAACAACGGACAATGAAC

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MQKKTLSDVAIQGKRVLMRVDFNVPIDEEKNITDDKRIVEALPSIKKIIDGGGRLILMSHLGRPKGKVNAEFSLAPVAHR
LSELLDTPVAMAKDCIGTEVMQAALALQDGEVMLLENLRFHAEEEANNPDFAKELASLGEIFVNDAFGTAHRAHASTEGI
THYVPVAVAGYLIEKELNYLGKALDNPERPFVAILGGSKISGKIDVLENLFTKVDTVLIGGAMVFTFFKAQGLNVGNSLV
EDNKLDLAQALLKQAADKGINLLLPDDVLVAATISSDASSHVEAVNSMSDGMIGVDIGPKTIEKYRNEILAARTVLWNGP
MGVFEIDNFAEGTFAIAKALAEATSSGAITIVGGGDSAAAIAKAALSDSITHISTGGGASLEFLEGKALPGIEALND

Sequences:

>Translated_397_residues
MQKKTLSDVAIQGKRVLMRVDFNVPIDEEKNITDDKRIVEALPSIKKIIDGGGRLILMSHLGRPKGKVNAEFSLAPVAHR
LSELLDTPVAMAKDCIGTEVMQAALALQDGEVMLLENLRFHAEEEANNPDFAKELASLGEIFVNDAFGTAHRAHASTEGI
THYVPVAVAGYLIEKELNYLGKALDNPERPFVAILGGSKISGKIDVLENLFTKVDTVLIGGAMVFTFFKAQGLNVGNSLV
EDNKLDLAQALLKQAADKGINLLLPDDVLVAATISSDASSHVEAVNSMSDGMIGVDIGPKTIEKYRNEILAARTVLWNGP
MGVFEIDNFAEGTFAIAKALAEATSSGAITIVGGGDSAAAIAKAALSDSITHISTGGGASLEFLEGKALPGIEALND
>Mature_397_residues
MQKKTLSDVAIQGKRVLMRVDFNVPIDEEKNITDDKRIVEALPSIKKIIDGGGRLILMSHLGRPKGKVNAEFSLAPVAHR
LSELLDTPVAMAKDCIGTEVMQAALALQDGEVMLLENLRFHAEEEANNPDFAKELASLGEIFVNDAFGTAHRAHASTEGI
THYVPVAVAGYLIEKELNYLGKALDNPERPFVAILGGSKISGKIDVLENLFTKVDTVLIGGAMVFTFFKAQGLNVGNSLV
EDNKLDLAQALLKQAADKGINLLLPDDVLVAATISSDASSHVEAVNSMSDGMIGVDIGPKTIEKYRNEILAARTVLWNGP
MGVFEIDNFAEGTFAIAKALAEATSSGAITIVGGGDSAAAIAKAALSDSITHISTGGGASLEFLEGKALPGIEALND

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family

Homologues:

Organism=Homo sapiens, GI4505763, Length=415, Percent_Identity=44.8192771084337, Blast_Score=355, Evalue=3e-98,
Organism=Homo sapiens, GI31543397, Length=415, Percent_Identity=43.855421686747, Blast_Score=351, Evalue=6e-97,
Organism=Escherichia coli, GI1789294, Length=394, Percent_Identity=43.4010152284264, Blast_Score=301, Evalue=4e-83,
Organism=Caenorhabditis elegans, GI17508823, Length=414, Percent_Identity=45.4106280193237, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6319857, Length=412, Percent_Identity=43.9320388349515, Blast_Score=345, Evalue=5e-96,
Organism=Drosophila melanogaster, GI24581203, Length=416, Percent_Identity=45.4326923076923, Blast_Score=352, Evalue=3e-97,
Organism=Drosophila melanogaster, GI17136394, Length=413, Percent_Identity=44.3099273607748, Blast_Score=330, Evalue=7e-91,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): PGK_CHLPD (A1BJZ1)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_913142.1
- ProteinModelPortal:   A1BJZ1
- SMR:   A1BJZ1
- STRING:   A1BJZ1
- GeneID:   4569978
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2734
- NMPDR:   fig|290317.7.peg.2855
- eggNOG:   COG0126
- HOGENOM:   HBG453500
- OMA:   LSYFSKA
- ProtClustDB:   PRK00073
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00145
- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824
- Gene3D:   G3DSA:3.40.50.1270
- Gene3D:   G3DSA:3.40.50.1260
- PANTHER:   PTHR11406
- PIRSF:   PIRSF000724
- PRINTS:   PR00477

Pfam domain/function: PF00162 PGK; SSF53748 PGK

EC number: =2.7.2.3

Molecular weight: Translated: 42001; Mature: 42001

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: BINDING 37-37 BINDING 119-119 BINDING 152-152 BINDING 203-203 BINDING 294-294 BINDING 325-325

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKKTLSDVAIQGKRVLMRVDFNVPIDEEKNITDDKRIVEALPSIKKIIDGGGRLILMSH
CCCCHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEC
LGRPKGKVNAEFSLAPVAHRLSELLDTPVAMAKDCIGTEVMQAALALQDGEVMLLENLRF
CCCCCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHH
HAEEEANNPDFAKELASLGEIFVNDAFGTAHRAHASTEGITHYVPVAVAGYLIEKELNYL
HCHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
GKALDNPERPFVAILGGSKISGKIDVLENLFTKVDTVLIGGAMVFTFFKAQGLNVGNSLV
HHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
EDNKLDLAQALLKQAADKGINLLLPDDVLVAATISSDASSHVEAVNSMSDGMIGVDIGPK
CCCHHHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCHHHHHHHHHHHCCCEEEECCCHH
TIEKYRNEILAARTVLWNGPMGVFEIDNFAEGTFAIAKALAEATSSGAITIVGGGDSAAA
HHHHHHHHHHHHHHHEECCCCCEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHH
IAKAALSDSITHISTGGGASLEFLEGKALPGIEALND
HHHHHHHCCCCEEECCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MQKKTLSDVAIQGKRVLMRVDFNVPIDEEKNITDDKRIVEALPSIKKIIDGGGRLILMSH
CCCCHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEC
LGRPKGKVNAEFSLAPVAHRLSELLDTPVAMAKDCIGTEVMQAALALQDGEVMLLENLRF
CCCCCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHH
HAEEEANNPDFAKELASLGEIFVNDAFGTAHRAHASTEGITHYVPVAVAGYLIEKELNYL
HCHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
GKALDNPERPFVAILGGSKISGKIDVLENLFTKVDTVLIGGAMVFTFFKAQGLNVGNSLV
HHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
EDNKLDLAQALLKQAADKGINLLLPDDVLVAATISSDASSHVEAVNSMSDGMIGVDIGPK
CCCHHHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCHHHHHHHHHHHCCCEEEECCCHH
TIEKYRNEILAARTVLWNGPMGVFEIDNFAEGTFAIAKALAEATSSGAITIVGGGDSAAA
HHHHHHHHHHHHHHHEECCCCCEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHH
IAKAALSDSITHISTGGGASLEFLEGKALPGIEALND
HHHHHHHCCCCEEECCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA