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The map label for this gene is rsmH

Identifier: 119358493

GI number: 119358493

Start: 3121326

End: 3122315

Strand: Reverse

Name: rsmH

Synonym: Cpha266_2729

Alternate gene names: 119358493

Gene position: 3122315-3121326 (Counterclockwise)

Preceding gene: 119358494

Following gene: 119358492

Centisome position: 99.63

GC content: 51.21

Gene sequence:

>990_bases
ATGAAACGTAGCGCTTATCATGAGCCTGTTCTTGCTGCTCAAGTTACGGATTTTCTGGTCCTGAGACCGGGCATTTATAT
CGACGGAACGCTTGGCGGCGGAGGGCACGCTCTTGCCATCATGAGAGCGCTTGAGACGGCAGGTTTTGAAAAAAACTCTC
TTCTGATCGGCATTGATCAGGACGATGAGGCGCTGCACGCTGCCAGCACGACACTTTCGTGGTATAAAGAGACGACGGTT
CTTGTAAAAGGCAATTTCAGCGACGTACGCAGTATTCTTGGAAAGGTATGCAAGCAGAGAGGCCTGGTCAGTCGAGCGGC
TGGAATTCTTCTGGATCTCGGGGTCTCCTCTTCACAGATTGATACAGCGGGCCGGGGGTTCAGCTATTTGCAGAAAGGCC
CTCTCGATATGAGGATGGATAGGTGTTCATCGACGACGGCCGCAGATATTGTCAACACCCTGGATGAAAAAGAACTTGCG
GGCCTTTTTTTTCGGTATGGAGAGGAGCCTCGCAGCAGAATGATCGCAAGACACATTGTAAACTATCGGGAACAGACAGG
AGCGGTGACCGGCACGGAGGTGCTTGCGGCAATTATTCGAAACGCCGAGAGAGACCCGCATAAACAGATCAAAACGCTTT
CCCGCGTTTTTCAGGCGCTGAGAATTGAGGTCAATCAGGAGCTTGAGGTGCTCAAACAGGCACTCAGCGACGGCGTGGAT
TGTCTTGATTATCACGGACGAATGGCTGTTATCAGTTATCACTCTCTTGAAGACAGGATCGTCAAATCATTTTTTGTTGA
AAAATCAAAAAGCGACTGGGGCCCGAAAGGAGTTGGCATGCGTGAACCGTTACATAAAGGGGTGCTCGGCCTGGTTACCC
GAAAGCCGCTCATCGCCGATGAAAAGGAAATTCAGGAAAATCCAAGAGCGCGCAGCGCGAAATTGCGTGTTGTTGAGAAC
GTGGCAACAGGGGGCTCCCATGCAGAGTGA

Upstream 100 bases:

>100_bases
ATACCAAAATGATTGTCTGGGCTCCCGAACGACTCTCTCTTCTTGTTATGGAAAATGCTGAGCGGTACTCCTCGTTAGCG
CGAAGATATTTTTGAAGGCC

Downstream 100 bases:

>100_bases
CAAGGATAAACGATTTTCTCTCTCGCAGTTTACCGGAATCCTGAAAACAGGATGGCAGGGGAAAAGTGATGAAAAAACGC
CACAGGGCAACTCCCCTTCC

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKRSAYHEPVLAAQVTDFLVLRPGIYIDGTLGGGGHALAIMRALETAGFEKNSLLIGIDQDDEALHAASTTLSWYKETTV
LVKGNFSDVRSILGKVCKQRGLVSRAAGILLDLGVSSSQIDTAGRGFSYLQKGPLDMRMDRCSSTTAADIVNTLDEKELA
GLFFRYGEEPRSRMIARHIVNYREQTGAVTGTEVLAAIIRNAERDPHKQIKTLSRVFQALRIEVNQELEVLKQALSDGVD
CLDYHGRMAVISYHSLEDRIVKSFFVEKSKSDWGPKGVGMREPLHKGVLGLVTRKPLIADEKEIQENPRARSAKLRVVEN
VATGGSHAE

Sequences:

>Translated_329_residues
MKRSAYHEPVLAAQVTDFLVLRPGIYIDGTLGGGGHALAIMRALETAGFEKNSLLIGIDQDDEALHAASTTLSWYKETTV
LVKGNFSDVRSILGKVCKQRGLVSRAAGILLDLGVSSSQIDTAGRGFSYLQKGPLDMRMDRCSSTTAADIVNTLDEKELA
GLFFRYGEEPRSRMIARHIVNYREQTGAVTGTEVLAAIIRNAERDPHKQIKTLSRVFQALRIEVNQELEVLKQALSDGVD
CLDYHGRMAVISYHSLEDRIVKSFFVEKSKSDWGPKGVGMREPLHKGVLGLVTRKPLIADEKEIQENPRARSAKLRVVEN
VATGGSHAE
>Mature_329_residues
MKRSAYHEPVLAAQVTDFLVLRPGIYIDGTLGGGGHALAIMRALETAGFEKNSLLIGIDQDDEALHAASTTLSWYKETTV
LVKGNFSDVRSILGKVCKQRGLVSRAAGILLDLGVSSSQIDTAGRGFSYLQKGPLDMRMDRCSSTTAADIVNTLDEKELA
GLFFRYGEEPRSRMIARHIVNYREQTGAVTGTEVLAAIIRNAERDPHKQIKTLSRVFQALRIEVNQELEVLKQALSDGVD
CLDYHGRMAVISYHSLEDRIVKSFFVEKSKSDWGPKGVGMREPLHKGVLGLVTRKPLIADEKEIQENPRARSAKLRVVEN
VATGGSHAE

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=348, Percent_Identity=35.9195402298851, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI165377202, Length=197, Percent_Identity=38.0710659898477, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1786270, Length=322, Percent_Identity=40.9937888198758, Blast_Score=203, Evalue=1e-53,
Organism=Drosophila melanogaster, GI62472493, Length=342, Percent_Identity=34.2105263157895, Blast_Score=141, Evalue=7e-34,
Organism=Drosophila melanogaster, GI28571637, Length=342, Percent_Identity=34.2105263157895, Blast_Score=141, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_CHLPD (A1BJY6)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_913137.1
- ProteinModelPortal:   A1BJY6
- SMR:   A1BJY6
- STRING:   A1BJY6
- GeneID:   4569973
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2729
- NMPDR:   fig|290317.7.peg.2850
- eggNOG:   COG0275
- HOGENOM:   HBG302779
- OMA:   PQLDDPE
- ProtClustDB:   CLSK637125
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 36188; Mature: 36188

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: BINDING 59-59 BINDING 86-86 BINDING 112-112 BINDING 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSAYHEPVLAAQVTDFLVLRPGIYIDGTLGGGGHALAIMRALETAGFEKNSLLIGIDQ
CCCCCCCCCHHHHHHHHHHEECCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEECC
DDEALHAASTTLSWYKETTVLVKGNFSDVRSILGKVCKQRGLVSRAAGILLDLGVSSSQI
CCHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCCCC
DTAGRGFSYLQKGPLDMRMDRCSSTTAADIVNTLDEKELAGLFFRYGEEPRSRMIARHIV
CCCCCCHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
NYREQTGAVTGTEVLAAIIRNAERDPHKQIKTLSRVFQALRIEVNQELEVLKQALSDGVD
HHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCH
CLDYHGRMAVISYHSLEDRIVKSFFVEKSKSDWGPKGVGMREPLHKGVLGLVTRKPLIAD
HHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
EKEIQENPRARSAKLRVVENVATGGSHAE
HHHHHCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKRSAYHEPVLAAQVTDFLVLRPGIYIDGTLGGGGHALAIMRALETAGFEKNSLLIGIDQ
CCCCCCCCCHHHHHHHHHHEECCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEECC
DDEALHAASTTLSWYKETTVLVKGNFSDVRSILGKVCKQRGLVSRAAGILLDLGVSSSQI
CCHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCCCC
DTAGRGFSYLQKGPLDMRMDRCSSTTAADIVNTLDEKELAGLFFRYGEEPRSRMIARHIV
CCCCCCHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
NYREQTGAVTGTEVLAAIIRNAERDPHKQIKTLSRVFQALRIEVNQELEVLKQALSDGVD
HHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCH
CLDYHGRMAVISYHSLEDRIVKSFFVEKSKSDWGPKGVGMREPLHKGVLGLVTRKPLIAD
HHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
EKEIQENPRARSAKLRVVENVATGGSHAE
HHHHHCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA