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The map label for this gene is plsC [H]

Identifier: 119358315

GI number: 119358315

Start: 2925474

End: 2926184

Strand: Direct

Name: plsC [H]

Synonym: Cpha266_2547

Alternate gene names: 119358315

Gene position: 2925474-2926184 (Clockwise)

Preceding gene: 119358314

Following gene: 119358318

Centisome position: 93.35

GC content: 50.91

Gene sequence:

>711_bases
ATGAACTACAGAACCCTGCTCTTTTTTCTCATCCTGGTACCGATCATGATTATCGGGATGAGCCTCTCGCTGCTCATCAA
CCTGTTTGACCGTACAGGCAACAGCTTTCACCGGATAGCCGCATGGTGGGGCCGGTTCAGCGCAAAACTGTTCGGCATTT
CAATCGAAACGATCGGCAGCGAAAACTACAGCGCCAATCAGCACTATCTGGTCATCAGCAATCATGCCGGAATGGCCGAC
ATTCCGCTCCTGCTTGGAACCATGAAACTCAACCTGCGGTTCGTTGCCAAAGAAGAACTGGGAAAAATACCGATATTCGG
CTGGGCGCTCAAACAGGCCGGATATATCATGATTCGCAGAGGTCAGAACAGAGACGCGCTCAAAAGCCTTCTGGACGCAG
CCGAAACGCTCAAAAACGGACGCTCCATCCATATATTCCCCGAAGGCACCCGCTCGGAAACAGGAGAAATGCTCCCGTTC
AAGCGAGGAGCATTTCTCGTAGCCCAGAAAGGCGGAGCTCCGATACTGCCGGTCACCATCATCGGCAGTCATTTGATTAC
CCCGAAAAAAAGCCTCAAGATCCACAAAGGCAAAATCAGGATCATTATCGGCAAGCCCATCACGCCATCGAACTTCGAAA
GTATTGAAGATCTCATGCTTGAATCATTCAGAACAATCGAAGGCAACCTGCAGCGCTACCGGTTCAACTGA

Upstream 100 bases:

>100_bases
TCGAAAGAAAAAAACAGGCCACCCTCATCAACGCCAGCTATAACGAACTGGCCGGGTTTCTGGAACATCTCGACAAGCAT
TAAACCGTTGCACCGCCGCC

Downstream 100 bases:

>100_bases
ATGCGTGAAAACACAAAAGGCACCCCCTAAAACTGACGATAGAGATTCACCATCTCAATAACGGTCATCGCGGCATCGAA
TCCCTTGTTTCCCGCTTTCG

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MNYRTLLFFLILVPIMIIGMSLSLLINLFDRTGNSFHRIAAWWGRFSAKLFGISIETIGSENYSANQHYLVISNHAGMAD
IPLLLGTMKLNLRFVAKEELGKIPIFGWALKQAGYIMIRRGQNRDALKSLLDAAETLKNGRSIHIFPEGTRSETGEMLPF
KRGAFLVAQKGGAPILPVTIIGSHLITPKKSLKIHKGKIRIIIGKPITPSNFESIEDLMLESFRTIEGNLQRYRFN

Sequences:

>Translated_236_residues
MNYRTLLFFLILVPIMIIGMSLSLLINLFDRTGNSFHRIAAWWGRFSAKLFGISIETIGSENYSANQHYLVISNHAGMAD
IPLLLGTMKLNLRFVAKEELGKIPIFGWALKQAGYIMIRRGQNRDALKSLLDAAETLKNGRSIHIFPEGTRSETGEMLPF
KRGAFLVAQKGGAPILPVTIIGSHLITPKKSLKIHKGKIRIIIGKPITPSNFESIEDLMLESFRTIEGNLQRYRFN
>Mature_236_residues
MNYRTLLFFLILVPIMIIGMSLSLLINLFDRTGNSFHRIAAWWGRFSAKLFGISIETIGSENYSANQHYLVISNHAGMAD
IPLLLGTMKLNLRFVAKEELGKIPIFGWALKQAGYIMIRRGQNRDALKSLLDAAETLKNGRSIHIFPEGTRSETGEMLPF
KRGAFLVAQKGGAPILPVTIIGSHLITPKKSLKIHKGKIRIIIGKPITPSNFESIEDLMLESFRTIEGNLQRYRFN

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=190, Percent_Identity=31.5789473684211, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI15100175, Length=190, Percent_Identity=31.5789473684211, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI6041665, Length=193, Percent_Identity=25.3886010362694, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1789395, Length=172, Percent_Identity=30.8139534883721, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17568319, Length=182, Percent_Identity=25.8241758241758, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564032, Length=145, Percent_Identity=30.3448275862069, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320151, Length=244, Percent_Identity=31.1475409836066, Blast_Score=108, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24641614, Length=208, Percent_Identity=29.3269230769231, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641612, Length=208, Percent_Identity=29.3269230769231, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281364648, Length=181, Percent_Identity=29.8342541436464, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24582856, Length=181, Percent_Identity=29.8342541436464, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24582854, Length=181, Percent_Identity=29.8342541436464, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 26526; Mature: 26526

Theoretical pI: Translated: 10.80; Mature: 10.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYRTLLFFLILVPIMIIGMSLSLLINLFDRTGNSFHRIAAWWGRFSAKLFGISIETIGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEEEEEEEEECC
ENYSANQHYLVISNHAGMADIPLLLGTMKLNLRFVAKEELGKIPIFGWALKQAGYIMIRR
CCCCCCCEEEEEECCCCCCHHHHHHEEEEEEEEEEEHHHCCCCCEEEEHHHHCCEEEEEE
GQNRDALKSLLDAAETLKNGRSIHIFPEGTRSETGEMLPFKRGAFLVAQKGGAPILPVTI
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCEEEHEE
IGSHLITPKKSLKIHKGKIRIIIGKPITPSNFESIEDLMLESFRTIEGNLQRYRFN
ECCCCCCCCHHCEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MNYRTLLFFLILVPIMIIGMSLSLLINLFDRTGNSFHRIAAWWGRFSAKLFGISIETIGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEEEEEEEEECC
ENYSANQHYLVISNHAGMADIPLLLGTMKLNLRFVAKEELGKIPIFGWALKQAGYIMIRR
CCCCCCCEEEEEECCCCCCHHHHHHEEEEEEEEEEEHHHCCCCCEEEEHHHHCCEEEEEE
GQNRDALKSLLDAAETLKNGRSIHIFPEGTRSETGEMLPFKRGAFLVAQKGGAPILPVTI
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCEEEHEE
IGSHLITPKKSLKIHKGKIRIIIGKPITPSNFESIEDLMLESFRTIEGNLQRYRFN
ECCCCCCCCHHCEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]