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The map label for this gene is fabF [H]

Identifier: 119358262

GI number: 119358262

Start: 2860448

End: 2861704

Strand: Direct

Name: fabF [H]

Synonym: Cpha266_2494

Alternate gene names: 119358262

Gene position: 2860448-2861704 (Clockwise)

Preceding gene: 119358261

Following gene: 119358263

Centisome position: 91.27

GC content: 50.84

Gene sequence:

>1257_bases
ATGGGTCAAGAGCGCAAAAGAATCGTCATAACCGGAATAGGGGTTCTCTCTCCTGTCGGCCTGAACAAAGAAGAGTTCTG
GAACGGACTTAAAGAGGGCAGGAGCGGTGCGGGGCCTATTACCTATTTCGACACGACCGATTTTCCGACAACTTTTGCTT
GCCAGCTCAAGGATTTTTCTGTCATCGATTACCTTGACAAAAAAACCTCCGACAGGATGGATCCATACTGTCAATACGGA
ATTATTGCCGCAGATCAGGCACTGAAGGATTCAGGGCTTGATCTGTCGGAAATAGATCCGCTCAGGATCGGCGTCGTGCA
TGGTTCGGGCATCGGAGGCCTTACGGTTTATGACCAGCAGTTCAGAAATTTTCTTGCAAAAGGCCCGAGGCGGATCAGTC
CGTTTTTTATTCCGATGCTTATCCCTGACATTGCGGCAGGACAGATTTCGATGCGGCATGGTCTCATGGGGCCTAATCAT
GCAACCGCCTCTGCCTGTGCAACTTCGCTTCACGCCATAATCGATGCATGGATGATTCTTCAGCTTGGAATGGCTGACTA
CATGATTTGCGGAGGCTCTGAAGCGCCGATAACCCCGATGAGTGTTGGCGGGTTTAATGCCGCCCGTGCGCTCTCAACGG
CCAATCATCATCCAGATAAAGCCTCACGACCCTACGATCGCGACCGTGATGGATTTGTAATGGGCGAAGGAGCCGGTTCA
CTTGTACTGGAAAGCCTCGAATCGGCAAAATCGCGCGGCGCAACCATATACGGAGAACTGGTGGGTGTTGGTGCTACTGC
AGATGCATACCACCTGACGGCGCCCCATCCGGAAGGAGCGGGAGCAGTCAATGCGATGAAAATCGCACTCGCTATGGCAG
GAATAAATCCCGATAAAATCGATTATATCAATACGCACGGCACAGCCACACCGTTGGGAGATATGGCTGAAATTACCGCG
ATTAAAAAAGTTTTCGGAGATCATGCCTGGAAGCTCAGCATCAGTTCCACCAAATCAATGACCGGACATCTGCTTGGAGC
TGCCGGCGTAGTCGAATCCATTGCATGCCTGCTTGCCATGAAGCACAAGACCGTTCCGCCAACCATCAACTGCGATAATC
TCGACCCGGCGATCGATCTGGATGTAACCCCGAACACAGCGAAAGAAAAAACAATCGAATACGCGTTGAACAACGGATTC
GGTTTTGGCGGCCATAATGCCTCACTCATATTCAGAAACGGCTCATCGATTTCATAA

Upstream 100 bases:

>100_bases
AGAAAAGATCAGTACGGTACAGCAGGCTATCGATTACATCGTAAAGAAGTAATTACTATCCAAAACAGTATCCTCCTCGG
CAATCATTAAAACAGATCAG

Downstream 100 bases:

>100_bases
CAACTCCTTCCCCATGGAGCAATTCTGGCAAAAACTGACCTTGTTTGCCTTCAAGCGTTCTGATACTAGCGGGGAGTCCT
GTATAAAAAAAATCGATCAG

Product: 3-oxoacyl-[acyl-carrier-protein] synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MGQERKRIVITGIGVLSPVGLNKEEFWNGLKEGRSGAGPITYFDTTDFPTTFACQLKDFSVIDYLDKKTSDRMDPYCQYG
IIAADQALKDSGLDLSEIDPLRIGVVHGSGIGGLTVYDQQFRNFLAKGPRRISPFFIPMLIPDIAAGQISMRHGLMGPNH
ATASACATSLHAIIDAWMILQLGMADYMICGGSEAPITPMSVGGFNAARALSTANHHPDKASRPYDRDRDGFVMGEGAGS
LVLESLESAKSRGATIYGELVGVGATADAYHLTAPHPEGAGAVNAMKIALAMAGINPDKIDYINTHGTATPLGDMAEITA
IKKVFGDHAWKLSISSTKSMTGHLLGAAGVVESIACLLAMKHKTVPPTINCDNLDPAIDLDVTPNTAKEKTIEYALNNGF
GFGGHNASLIFRNGSSIS

Sequences:

>Translated_418_residues
MGQERKRIVITGIGVLSPVGLNKEEFWNGLKEGRSGAGPITYFDTTDFPTTFACQLKDFSVIDYLDKKTSDRMDPYCQYG
IIAADQALKDSGLDLSEIDPLRIGVVHGSGIGGLTVYDQQFRNFLAKGPRRISPFFIPMLIPDIAAGQISMRHGLMGPNH
ATASACATSLHAIIDAWMILQLGMADYMICGGSEAPITPMSVGGFNAARALSTANHHPDKASRPYDRDRDGFVMGEGAGS
LVLESLESAKSRGATIYGELVGVGATADAYHLTAPHPEGAGAVNAMKIALAMAGINPDKIDYINTHGTATPLGDMAEITA
IKKVFGDHAWKLSISSTKSMTGHLLGAAGVVESIACLLAMKHKTVPPTINCDNLDPAIDLDVTPNTAKEKTIEYALNNGF
GFGGHNASLIFRNGSSIS
>Mature_417_residues
GQERKRIVITGIGVLSPVGLNKEEFWNGLKEGRSGAGPITYFDTTDFPTTFACQLKDFSVIDYLDKKTSDRMDPYCQYGI
IAADQALKDSGLDLSEIDPLRIGVVHGSGIGGLTVYDQQFRNFLAKGPRRISPFFIPMLIPDIAAGQISMRHGLMGPNHA
TASACATSLHAIIDAWMILQLGMADYMICGGSEAPITPMSVGGFNAARALSTANHHPDKASRPYDRDRDGFVMGEGAGSL
VLESLESAKSRGATIYGELVGVGATADAYHLTAPHPEGAGAVNAMKIALAMAGINPDKIDYINTHGTATPLGDMAEITAI
KKVFGDHAWKLSISSTKSMTGHLLGAAGVVESIACLLAMKHKTVPPTINCDNLDPAIDLDVTPNTAKEKTIEYALNNGFG
FGGHNASLIFRNGSSIS

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=414, Percent_Identity=44.6859903381643, Blast_Score=335, Evalue=4e-92,
Organism=Homo sapiens, GI223972627, Length=168, Percent_Identity=48.8095238095238, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI41872631, Length=423, Percent_Identity=25.0591016548463, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI1787337, Length=410, Percent_Identity=51.4634146341463, Blast_Score=390, Evalue=1e-109,
Organism=Escherichia coli, GI1788663, Length=427, Percent_Identity=39.344262295082, Blast_Score=254, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI71983541, Length=412, Percent_Identity=33.7378640776699, Blast_Score=238, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI71983535, Length=263, Percent_Identity=38.0228136882129, Blast_Score=184, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI212642053, Length=360, Percent_Identity=25.5555555555556, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17550940, Length=398, Percent_Identity=24.6231155778894, Blast_Score=98, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6320904, Length=451, Percent_Identity=35.920177383592, Blast_Score=254, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24644341, Length=417, Percent_Identity=43.6450839328537, Blast_Score=324, Evalue=9e-89,
Organism=Drosophila melanogaster, GI221330659, Length=357, Percent_Identity=24.6498599439776, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI19920632, Length=357, Percent_Identity=24.6498599439776, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24581345, Length=432, Percent_Identity=23.8425925925926, Blast_Score=96, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 44329; Mature: 44198

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQERKRIVITGIGVLSPVGLNKEEFWNGLKEGRSGAGPITYFDTTDFPTTFACQLKDFS
CCCCCCEEEEEECCHHCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEECCCH
VIDYLDKKTSDRMDPYCQYGIIAADQALKDSGLDLSEIDPLRIGVVHGSGIGGLTVYDQQ
HHHHHHHHCCCCCCHHHHCCEEEHHHHHHHCCCCHHHCCCEEEEEEECCCCCCEEEEHHH
FRNFLAKGPRRISPFFIPMLIPDIAAGQISMRHGLMGPNHATASACATSLHAIIDAWMIL
HHHHHHCCCCCCCCEEHHHHHCCCCCCCEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
QLGMADYMICGGSEAPITPMSVGGFNAARALSTANHHPDKASRPYDRDRDGFVMGEGAGS
HHCCHHEEEECCCCCCCCCEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCHH
LVLESLESAKSRGATIYGELVGVGATADAYHLTAPHPEGAGAVNAMKIALAMAGINPDKI
HHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEECCCCCCCCCHHHHEEEHHHCCCCCCCE
DYINTHGTATPLGDMAEITAIKKVFGDHAWKLSISSTKSMTGHLLGAAGVVESIACLLAM
EEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
KHKTVPPTINCDNLDPAIDLDVTPNTAKEKTIEYALNNGFGFGGHNASLIFRNGSSIS
HCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
GQERKRIVITGIGVLSPVGLNKEEFWNGLKEGRSGAGPITYFDTTDFPTTFACQLKDFS
CCCCCEEEEEECCHHCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEECCCH
VIDYLDKKTSDRMDPYCQYGIIAADQALKDSGLDLSEIDPLRIGVVHGSGIGGLTVYDQQ
HHHHHHHHCCCCCCHHHHCCEEEHHHHHHHCCCCHHHCCCEEEEEEECCCCCCEEEEHHH
FRNFLAKGPRRISPFFIPMLIPDIAAGQISMRHGLMGPNHATASACATSLHAIIDAWMIL
HHHHHHCCCCCCCCEEHHHHHCCCCCCCEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
QLGMADYMICGGSEAPITPMSVGGFNAARALSTANHHPDKASRPYDRDRDGFVMGEGAGS
HHCCHHEEEECCCCCCCCCEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCHH
LVLESLESAKSRGATIYGELVGVGATADAYHLTAPHPEGAGAVNAMKIALAMAGINPDKI
HHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEECCCCCCCCCHHHHEEEHHHCCCCCCCE
DYINTHGTATPLGDMAEITAIKKVFGDHAWKLSISSTKSMTGHLLGAAGVVESIACLLAM
EEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
KHKTVPPTINCDNLDPAIDLDVTPNTAKEKTIEYALNNGFGFGGHNASLIFRNGSSIS
HCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]