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The map label for this gene is adcA [H]

Identifier: 119358244

GI number: 119358244

Start: 2848359

End: 2849300

Strand: Reverse

Name: adcA [H]

Synonym: Cpha266_2476

Alternate gene names: 119358244

Gene position: 2849300-2848359 (Counterclockwise)

Preceding gene: 119358245

Following gene: 119358243

Centisome position: 90.92

GC content: 49.58

Gene sequence:

>942_bases
ATGTTTTTCATCCCGATCAGATTCATTGCCATTGCGCTTCTTCTGCTTTTTCCTTTTTTTTATTCCGGCTGTGTCTCAAA
ACCTGTTGAGAAACGGTTGCAGGTTGTCGCTTCGATTGCACCGCTTGCCTACTTTGCTGAAAAGATTGGCGGTGGTTACG
TGACGGTTTCCGTTATGGTTCCTCCTGGCGGTAATCCTCATACCTATGAACCGACGCCAAGGCAGATGTCGATGCTTGGC
AGCGCGAAGCTGTTTATAAAGGCAGGGTCCGGCGTTGAGTTTGAACTGGATTTGATGCAGAAGATTATGTCGATGTATCC
TGTTCTCAGGATCTGTAACGCCGCTTCGGGCATTCATTTAAAGCCTGCAGAGCATGATGGTGAGCATAGCGAAAGGCACG
ATTATCCAGATGAGCATAGCGAAAGGCACGATTATCCAGATGAGCATCGTCATGGCCTTGTTGATCCTCACTACTGGCTT
TCGCCTCGAAATGCTCTGGTTATTGCAGAGAATGTTGAGAGATCTCTTATCGAAGCCGATCCCGAGCGTACTGTCTTTTA
TCAGGCCAATGCCGACAGGTTGAAGCAAGAGCTGCATGGGCTTTCAAGCGAGATTCATGTAAAGCTTGCGTCGGTCTCGA
ATCGTCGTTTTCTTGTTTTTCATCCCGCATGGGGTTACTATGCTTCGGATTTTGCGCTGGAGCAGATTGCCGCAGAAGAG
GAGGGTAAGACGCTGACCCCCCGCCAGCTTGGGCGAGTCATTCAGAAAGCCAGAACAAACGGGATAAGAGTTGTCTTTGT
GTCCCCTCAGTTCAGCACCGTACAAGCGGAGACCATCGCAAGGGAAATAGGAGGTGTTACCCGGGCTGTCGATCCTCTTG
CTTTTGAGTATCAGGAAAATCTTCTCCGCGCTACCGATGCCTTCAAGGGAGGAATGCAGTGA

Upstream 100 bases:

>100_bases
ATGATGGGATGAAGATCGACGATTTCACGCTCGTCAGTCATATTGTTCAGCTTCAGGGGATTTGCGCTTCTTGCGCATCA
CCAGACACGGAGACATAATC

Downstream 100 bases:

>100_bases
ACCGGGTGCTTGTCGACTGCGATCGCCTTTCCGTTGTGCTTGATGGATCAAGGGTTCTCGATAATCTGACACTGCAGGTC
TGCGAGGGGGATTTTCTTGG

Product: periplasmic solute binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MFFIPIRFIAIALLLLFPFFYSGCVSKPVEKRLQVVASIAPLAYFAEKIGGGYVTVSVMVPPGGNPHTYEPTPRQMSMLG
SAKLFIKAGSGVEFELDLMQKIMSMYPVLRICNAASGIHLKPAEHDGEHSERHDYPDEHSERHDYPDEHRHGLVDPHYWL
SPRNALVIAENVERSLIEADPERTVFYQANADRLKQELHGLSSEIHVKLASVSNRRFLVFHPAWGYYASDFALEQIAAEE
EGKTLTPRQLGRVIQKARTNGIRVVFVSPQFSTVQAETIAREIGGVTRAVDPLAFEYQENLLRATDAFKGGMQ

Sequences:

>Translated_313_residues
MFFIPIRFIAIALLLLFPFFYSGCVSKPVEKRLQVVASIAPLAYFAEKIGGGYVTVSVMVPPGGNPHTYEPTPRQMSMLG
SAKLFIKAGSGVEFELDLMQKIMSMYPVLRICNAASGIHLKPAEHDGEHSERHDYPDEHSERHDYPDEHRHGLVDPHYWL
SPRNALVIAENVERSLIEADPERTVFYQANADRLKQELHGLSSEIHVKLASVSNRRFLVFHPAWGYYASDFALEQIAAEE
EGKTLTPRQLGRVIQKARTNGIRVVFVSPQFSTVQAETIAREIGGVTRAVDPLAFEYQENLLRATDAFKGGMQ
>Mature_313_residues
MFFIPIRFIAIALLLLFPFFYSGCVSKPVEKRLQVVASIAPLAYFAEKIGGGYVTVSVMVPPGGNPHTYEPTPRQMSMLG
SAKLFIKAGSGVEFELDLMQKIMSMYPVLRICNAASGIHLKPAEHDGEHSERHDYPDEHSERHDYPDEHRHGLVDPHYWL
SPRNALVIAENVERSLIEADPERTVFYQANADRLKQELHGLSSEIHVKLASVSNRRFLVFHPAWGYYASDFALEQIAAEE
EGKTLTPRQLGRVIQKARTNGIRVVFVSPQFSTVQAETIAREIGGVTRAVDPLAFEYQENLLRATDAFKGGMQ

Specific function: Part of the ATP-driven transport system AdcABC for zinc [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=262, Percent_Identity=27.0992366412214, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR006128
- InterPro:   IPR015304 [H]

Pfam domain/function: PF01297 SBP_bac_9; PF09223 YodA [H]

EC number: NA

Molecular weight: Translated: 35138; Mature: 35138

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFIPIRFIAIALLLLFPFFYSGCVSKPVEKRLQVVASIAPLAYFAEKIGGGYVTVSVMV
CEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
PPGGNPHTYEPTPRQMSMLGSAKLFIKAGSGVEFELDLMQKIMSMYPVLRICNAASGIHL
CCCCCCCCCCCCHHHHHHHCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEE
KPAEHDGEHSERHDYPDEHSERHDYPDEHRHGLVDPHYWLSPRNALVIAENVERSLIEAD
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCEECCCCEEEEECHHHHHHHHCC
PERTVFYQANADRLKQELHGLSSEIHVKLASVSNRRFLVFHPAWGYYASDFALEQIAAEE
CCCEEEEECCHHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHC
EGKTLTPRQLGRVIQKARTNGIRVVFVSPQFSTVQAETIAREIGGVTRAVDPLAFEYQEN
CCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHCHHHHHHHHH
LLRATDAFKGGMQ
HHHHHHHHCCCCC
>Mature Secondary Structure
MFFIPIRFIAIALLLLFPFFYSGCVSKPVEKRLQVVASIAPLAYFAEKIGGGYVTVSVMV
CEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
PPGGNPHTYEPTPRQMSMLGSAKLFIKAGSGVEFELDLMQKIMSMYPVLRICNAASGIHL
CCCCCCCCCCCCHHHHHHHCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEE
KPAEHDGEHSERHDYPDEHSERHDYPDEHRHGLVDPHYWLSPRNALVIAENVERSLIEAD
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCEECCCCEEEEECHHHHHHHHCC
PERTVFYQANADRLKQELHGLSSEIHVKLASVSNRRFLVFHPAWGYYASDFALEQIAAEE
CCCEEEEECCHHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHC
EGKTLTPRQLGRVIQKARTNGIRVVFVSPQFSTVQAETIAREIGGVTRAVDPLAFEYQEN
CCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHCHHHHHHHHH
LLRATDAFKGGMQ
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]