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The map label for this gene is moaC/mobA [H]

Identifier: 119358241

GI number: 119358241

Start: 2845205

End: 2846695

Strand: Direct

Name: moaC/mobA [H]

Synonym: Cpha266_2473

Alternate gene names: 119358241

Gene position: 2845205-2846695 (Clockwise)

Preceding gene: 119358235

Following gene: 119358255

Centisome position: 90.79

GC content: 49.63

Gene sequence:

>1491_bases
ATGATATGTATTAACTTTAAAAATGTTTTAATCCAAACTATAACCACGGAGTTTCACTATGGACATTCGCAGATGGATTC
TGGCTTTTGTTCTCCCTCCCGCCGCCGTCATGAACAAAGAAGCCGGCACAATAATGCTCACCGGAATTCTGACCCTGTTA
GGATGGGTGCCGGGCGTTACAGCGGCCGTGATCATGCTGGTTCAGGAACAGAGACAGGCCAAAGCATAAGGGACTCCACT
CCTGCACCATTTTCCTGTACAGAGCTGACGATGGGACTCTATTGCAGACCGTTTCATCTTCAACTCTGTTTTTTCCGGCT
TAGGGACGGATCGAACCTGCATTGCAGACGACCGCTCATCTTTTCAGCAATGCCAATACCACCCATGCATTTTCATCCTT
ATGAAGCTGCTTTCTGCGGTTACTCCGGCTCAGGCAAAACAACGCTGATTGCCGCTGTTATCCGCAAGCTCTCAGAGCAT
TTTTCTGTCGGCTACTACAAACACGGCTGTCACCGGTTCGATATTGACCGCGAAGGAAAAGATTCATTTGTGATTAAAGC
GTCCGGAGCGACAGCCGTCATGATTGCTGATCCTGCCAAACAGGCGGTGATCATCGACAACGGAAAGACCCGGCTCCGGG
AACGTCAGATTTTTCTGGATCTCGACCTGCTTTTGGTCGAAGGGCTCAAGGAGCTGCCGCTACCGAAAATCGTGATGATT
GACCAGAACAGGAAAATTCTTGATCTGCTCGACAACGGTAGCGTTACCAATGTCGCTGCGCTCGTAAAAAGCGATCGTCA
GACGCTCGACAAACAGTACGGTATACCGGTCTTTCACCGTAACGATACCGATGAGATCAGCGACTTTATTGCATCCATGC
TTTTGCAGAAAAGCATGGAAACACCCCTTTTCGGTCTTGTCCTTGCAGGAGGACAAAGTTCAAGAATGGGAAGTGACAAA
GCGCTGATTTCCTACCACAGCGAAAACCAGCTTGTCAGAACAGCACAACTTATGGAGAAGTGCTGCCAGAAGGTGTTCAT
ATCCTGTCGAGATGATCAGAAAGAGCATTACCGTCCATACGGCTACCCGCTTATTACAGACCGATATCTCAACATCGGAC
CGCTCGGAGGTCTGCTATCAGCACAAATGGAACACCCTCGTACTGCCTGGATGACCGTTGCCTGCGACCTGCCGTTTCTC
GACGAACAGGTATTTCGGCAGCTCTCCCAGCGCCGAAACCCGTTTCGCTATGCCACGGCGTTCATGAATCCATCTTCAAA
CAGCCTTGAACCGCTTTGCAGTTGTTACGAACCAAAATCGAGAGACCGGCTTTTTTCCATGCATGCCGAAAGCAATAACT
CCCTCTTTTCATTTCTGGAGCAATCGCGTATTGAACCACTCACCATGGAGCATGCAGCGAGACTACGCAACATCAACGAC
CCGGAATCGATGCGTACCGCAAAAAGGGAATGCCGCACGCTACATGAATAG

Upstream 100 bases:

>100_bases
AAGGGAAATGAATTTACAACATTATGGCTTAAATGCAAATAATAGTGTTCAGAGATCAATCAAACAATAAAGAGCCTGGC
ATTTTGCATTGGTTGTTTTC

Downstream 100 bases:

>100_bases
CGCCGGCTGCCCTTGACCGCTCTATTGATACAATGCACTGAGCCTCCCGACTCACGAAAGCTCTTCTCCCCGACGATTAT
CGGTCCATCAATGAAACTCG

Product: putative bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobB/MobA

Products: NA

Alternate protein names: Molybdenum cofactor biosynthesis protein C; Molybdopterin-guanine dinucleotide biosynthesis protein A [H]

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MICINFKNVLIQTITTEFHYGHSQMDSGFCSPSRRRHEQRSRHNNAHRNSDPVRMGAGRYSGRDHAGSGTETGQSIRDST
PAPFSCTELTMGLYCRPFHLQLCFFRLRDGSNLHCRRPLIFSAMPIPPMHFHPYEAAFCGYSGSGKTTLIAAVIRKLSEH
FSVGYYKHGCHRFDIDREGKDSFVIKASGATAVMIADPAKQAVIIDNGKTRLRERQIFLDLDLLLVEGLKELPLPKIVMI
DQNRKILDLLDNGSVTNVAALVKSDRQTLDKQYGIPVFHRNDTDEISDFIASMLLQKSMETPLFGLVLAGGQSSRMGSDK
ALISYHSENQLVRTAQLMEKCCQKVFISCRDDQKEHYRPYGYPLITDRYLNIGPLGGLLSAQMEHPRTAWMTVACDLPFL
DEQVFRQLSQRRNPFRYATAFMNPSSNSLEPLCSCYEPKSRDRLFSMHAESNNSLFSFLEQSRIEPLTMEHAARLRNIND
PESMRTAKRECRTLHE

Sequences:

>Translated_496_residues
MICINFKNVLIQTITTEFHYGHSQMDSGFCSPSRRRHEQRSRHNNAHRNSDPVRMGAGRYSGRDHAGSGTETGQSIRDST
PAPFSCTELTMGLYCRPFHLQLCFFRLRDGSNLHCRRPLIFSAMPIPPMHFHPYEAAFCGYSGSGKTTLIAAVIRKLSEH
FSVGYYKHGCHRFDIDREGKDSFVIKASGATAVMIADPAKQAVIIDNGKTRLRERQIFLDLDLLLVEGLKELPLPKIVMI
DQNRKILDLLDNGSVTNVAALVKSDRQTLDKQYGIPVFHRNDTDEISDFIASMLLQKSMETPLFGLVLAGGQSSRMGSDK
ALISYHSENQLVRTAQLMEKCCQKVFISCRDDQKEHYRPYGYPLITDRYLNIGPLGGLLSAQMEHPRTAWMTVACDLPFL
DEQVFRQLSQRRNPFRYATAFMNPSSNSLEPLCSCYEPKSRDRLFSMHAESNNSLFSFLEQSRIEPLTMEHAARLRNIND
PESMRTAKRECRTLHE
>Mature_496_residues
MICINFKNVLIQTITTEFHYGHSQMDSGFCSPSRRRHEQRSRHNNAHRNSDPVRMGAGRYSGRDHAGSGTETGQSIRDST
PAPFSCTELTMGLYCRPFHLQLCFFRLRDGSNLHCRRPLIFSAMPIPPMHFHPYEAAFCGYSGSGKTTLIAAVIRKLSEH
FSVGYYKHGCHRFDIDREGKDSFVIKASGATAVMIADPAKQAVIIDNGKTRLRERQIFLDLDLLLVEGLKELPLPKIVMI
DQNRKILDLLDNGSVTNVAALVKSDRQTLDKQYGIPVFHRNDTDEISDFIASMLLQKSMETPLFGLVLAGGQSSRMGSDK
ALISYHSENQLVRTAQLMEKCCQKVFISCRDDQKEHYRPYGYPLITDRYLNIGPLGGLLSAQMEHPRTAWMTVACDLPFL
DEQVFRQLSQRRNPFRYATAFMNPSSNSLEPLCSCYEPKSRDRLFSMHAESNNSLFSFLEQSRIEPLTMEHAARLRNIND
PESMRTAKRECRTLHE

Specific function: Links a guanosine 5'-phosphate to molydopterin (MPT) forming molybdopterin guanine dinucleotide (MGD) [H]

COG id: COG0746

COG function: function code H; Molybdopterin-guanine dinucleotide biosynthesis protein A

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the mobA family [H]

Homologues:

Organism=Escherichia coli, GI145693204, Length=171, Percent_Identity=28.0701754385965, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR002820
- InterPro:   IPR013482 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 56413; Mature: 56413

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICINFKNVLIQTITTEFHYGHSQMDSGFCSPSRRRHEQRSRHNNAHRNSDPVRMGAGRY
CEEEEHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCC
SGRDHAGSGTETGQSIRDSTPAPFSCTELTMGLYCRPFHLQLCFFRLRDGSNLHCRRPLI
CCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHCCCHHHHEEEEEEECCCCCCEECCCEE
FSAMPIPPMHFHPYEAAFCGYSGSGKTTLIAAVIRKLSEHFSVGYYKHGCHRFDIDREGK
EECCCCCCCCCCCCHHEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCEEECCCCCCC
DSFVIKASGATAVMIADPAKQAVIIDNGKTRLRERQIFLDLDLLLVEGLKELPLPKIVMI
CCEEEEECCCEEEEEECCCCCEEEEECCHHHHHHHHHEEHHHHHHHHHHHHCCCCEEEEE
DQNRKILDLLDNGSVTNVAALVKSDRQTLDKQYGIPVFHRNDTDEISDFIASMLLQKSME
ECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCC
TPLFGLVLAGGQSSRMGSDKALISYHSENQLVRTAQLMEKCCQKVFISCRDDQKEHYRPY
CCEEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCC
GYPLITDRYLNIGPLGGLLSAQMEHPRTAWMTVACDLPFLDEQVFRQLSQRRNPFRYATA
CCCEEECCCCCCCCCCHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEE
FMNPSSNSLEPLCSCYEPKSRDRLFSMHAESNNSLFSFLEQSRIEPLTMEHAARLRNIND
EECCCCCCHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCC
PESMRTAKRECRTLHE
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MICINFKNVLIQTITTEFHYGHSQMDSGFCSPSRRRHEQRSRHNNAHRNSDPVRMGAGRY
CEEEEHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCC
SGRDHAGSGTETGQSIRDSTPAPFSCTELTMGLYCRPFHLQLCFFRLRDGSNLHCRRPLI
CCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHCCCHHHHEEEEEEECCCCCCEECCCEE
FSAMPIPPMHFHPYEAAFCGYSGSGKTTLIAAVIRKLSEHFSVGYYKHGCHRFDIDREGK
EECCCCCCCCCCCCHHEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCEEECCCCCCC
DSFVIKASGATAVMIADPAKQAVIIDNGKTRLRERQIFLDLDLLLVEGLKELPLPKIVMI
CCEEEEECCCEEEEEECCCCCEEEEECCHHHHHHHHHEEHHHHHHHHHHHHCCCCEEEEE
DQNRKILDLLDNGSVTNVAALVKSDRQTLDKQYGIPVFHRNDTDEISDFIASMLLQKSME
ECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCC
TPLFGLVLAGGQSSRMGSDKALISYHSENQLVRTAQLMEKCCQKVFISCRDDQKEHYRPY
CCEEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCC
GYPLITDRYLNIGPLGGLLSAQMEHPRTAWMTVACDLPFLDEQVFRQLSQRRNPFRYATA
CCCEEECCCCCCCCCCHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEE
FMNPSSNSLEPLCSCYEPKSRDRLFSMHAESNNSLFSFLEQSRIEPLTMEHAARLRNIND
EECCCCCCHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCC
PESMRTAKRECRTLHE
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]