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The map label for this gene is cysS [H]

Identifier: 119358160

GI number: 119358160

Start: 2779938

End: 2781392

Strand: Direct

Name: cysS [H]

Synonym: Cpha266_2392

Alternate gene names: 119358160

Gene position: 2779938-2781392 (Clockwise)

Preceding gene: 119358153

Following gene: 119358162

Centisome position: 88.71

GC content: 48.18

Gene sequence:

>1455_bases
ATGTCTTTATTTATATACAATTCTCTGGGGAAAAAAAAGGAACAATTTGAATCTCTTTACCCCGGACTGGTCACCATGTA
TGTCTGCGGACCGACGGTTTACGGCCATGCCCACCTCGGACATGCCAAAAGCTATGTTTCGTTTGACGTTGTTGCCCGCT
GGCTGCGCCATATCGGTTTCAGGGTAAAGTATGTGCAGAATATAACCGATGTCGGTCACCTTACCGATGACGGCGATGAT
GGCGAGGATAAAATTGAACGACAGGCGAGAACAGAAAAAACCGACCCAATGGAAATTGCGCAGTTCTACACGCGCAGCTT
CTATGAAGACATGGACCGACTTGGTGTTGAGCGGCCAAACATTGCTCCGACGGCTACCGGACACATACCGGAACAGATCG
CACTGATCGAAAAGCTTATAGCTTCGGAACACGCTTATGTGGTTAATGGCAATGTCTATTTCTCGGTGGACTCTTTCCCT
GGCTATGGAAAACTCTCGGGACGCACCGATCAGGATGCCGTGCTATCAGGCAACAGGGTTCAGCTCCGATCTGAAAAACG
AAATCCTTCCGATTTTGCGCTATGGAAAAAAGCCGAGCCCGGCCATATGATGCAATGGCACTCGCCATGGGGCAGCGGCT
TTCCCGGCTGGCATGTCGAATGTTCAGCGATGGCAACAAAATACCTTGGCCCGACAATTGATATTCACGGTGGAGGAATG
GAAAATAAATTCCCGCACCATGACTGTGAGATAGCTCAGTCAGAGGCTGCAAGCGGCAAACCGTTCGTTCGTTACTGGAT
GCATAACAACATGGTGACGGTCAATGGCACGAAAATGGGGAAATCACTGAAAAACTCGGTTAACCTTAAAGATCTCTTCA
AAAGAGTTGACCCTGTTGTTATCCGGTTCTTCATTCTACAATCGCACTATCGATCACCGCTTGATTATTCTGAAACCGCC
ATCAGGGCATCGCAGACAGGGCTGGAAAAACTTCACGACACCATGCGACGTTTGCTTCAGGCTTTACCTGGATCAGGTGA
GCTTAATATTTCAGCCTTCATCGACAGGTTTGAATCAGCCATGAACGACGACTTCAATACCCCCATAGCAATTTCCGTGC
TGTTTGATTTTTCAAAATCGCTGAACAGTGCGCTTGACCAGGAGTGCGGGCTCTCCGAAACAGCACTCGATAATGCAAAA
AGATTTCTCGGGATGTATGGCACTACTCTCCTTGGCATTATCCCTCCAGAGGCTCAGCCACTCACAACCGGCATGGAAAA
TGGGGAGAAAACGCTTGACGAAGTGATCTCTATTCTACTCGATATGCGTAAGGAAGCAAGGGAACAGAAAAACTATCCAC
TCAGCGATACCATAAGAGACAGGCTTCTTGAAGCGGGAATCGAGGTCAAAGACACAAAAGATGGTGCAAGCTGGTCCAAG
GTTTCAAACCGTTAA

Upstream 100 bases:

>100_bases
GAAAAAAGCAAACTAAAAACCTTGTGTTAAAAACCCAAATGTTTAACTTTCATCAGGTTTTTGATACGCTATGCACTGCC
AACCGGCTTAACAATACACG

Downstream 100 bases:

>100_bases
AGATAGCTGTCAAAATCGTCTCGACGGAGTTGATCAAAGGCAGTGCCAACTTTATGCGAATCCCCTTTATTGCAAATAAG
CAGTGCGTCACCTGTATCGA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSLFIYNSLGKKKEQFESLYPGLVTMYVCGPTVYGHAHLGHAKSYVSFDVVARWLRHIGFRVKYVQNITDVGHLTDDGDD
GEDKIERQARTEKTDPMEIAQFYTRSFYEDMDRLGVERPNIAPTATGHIPEQIALIEKLIASEHAYVVNGNVYFSVDSFP
GYGKLSGRTDQDAVLSGNRVQLRSEKRNPSDFALWKKAEPGHMMQWHSPWGSGFPGWHVECSAMATKYLGPTIDIHGGGM
ENKFPHHDCEIAQSEAASGKPFVRYWMHNNMVTVNGTKMGKSLKNSVNLKDLFKRVDPVVIRFFILQSHYRSPLDYSETA
IRASQTGLEKLHDTMRRLLQALPGSGELNISAFIDRFESAMNDDFNTPIAISVLFDFSKSLNSALDQECGLSETALDNAK
RFLGMYGTTLLGIIPPEAQPLTTGMENGEKTLDEVISILLDMRKEAREQKNYPLSDTIRDRLLEAGIEVKDTKDGASWSK
VSNR

Sequences:

>Translated_484_residues
MSLFIYNSLGKKKEQFESLYPGLVTMYVCGPTVYGHAHLGHAKSYVSFDVVARWLRHIGFRVKYVQNITDVGHLTDDGDD
GEDKIERQARTEKTDPMEIAQFYTRSFYEDMDRLGVERPNIAPTATGHIPEQIALIEKLIASEHAYVVNGNVYFSVDSFP
GYGKLSGRTDQDAVLSGNRVQLRSEKRNPSDFALWKKAEPGHMMQWHSPWGSGFPGWHVECSAMATKYLGPTIDIHGGGM
ENKFPHHDCEIAQSEAASGKPFVRYWMHNNMVTVNGTKMGKSLKNSVNLKDLFKRVDPVVIRFFILQSHYRSPLDYSETA
IRASQTGLEKLHDTMRRLLQALPGSGELNISAFIDRFESAMNDDFNTPIAISVLFDFSKSLNSALDQECGLSETALDNAK
RFLGMYGTTLLGIIPPEAQPLTTGMENGEKTLDEVISILLDMRKEAREQKNYPLSDTIRDRLLEAGIEVKDTKDGASWSK
VSNR
>Mature_483_residues
SLFIYNSLGKKKEQFESLYPGLVTMYVCGPTVYGHAHLGHAKSYVSFDVVARWLRHIGFRVKYVQNITDVGHLTDDGDDG
EDKIERQARTEKTDPMEIAQFYTRSFYEDMDRLGVERPNIAPTATGHIPEQIALIEKLIASEHAYVVNGNVYFSVDSFPG
YGKLSGRTDQDAVLSGNRVQLRSEKRNPSDFALWKKAEPGHMMQWHSPWGSGFPGWHVECSAMATKYLGPTIDIHGGGME
NKFPHHDCEIAQSEAASGKPFVRYWMHNNMVTVNGTKMGKSLKNSVNLKDLFKRVDPVVIRFFILQSHYRSPLDYSETAI
RASQTGLEKLHDTMRRLLQALPGSGELNISAFIDRFESAMNDDFNTPIAISVLFDFSKSLNSALDQECGLSETALDNAKR
FLGMYGTTLLGIIPPEAQPLTTGMENGEKTLDEVISILLDMRKEAREQKNYPLSDTIRDRLLEAGIEVKDTKDGASWSKV
SNR

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=527, Percent_Identity=34.3453510436433, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI10835051, Length=444, Percent_Identity=31.5315315315315, Blast_Score=192, Evalue=7e-49,
Organism=Homo sapiens, GI21269877, Length=444, Percent_Identity=31.5315315315315, Blast_Score=191, Evalue=9e-49,
Organism=Homo sapiens, GI303304987, Length=444, Percent_Identity=31.5315315315315, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI62240992, Length=444, Percent_Identity=31.5315315315315, Blast_Score=191, Evalue=1e-48,
Organism=Escherichia coli, GI1786737, Length=481, Percent_Identity=41.1642411642412, Blast_Score=353, Evalue=1e-98,
Organism=Caenorhabditis elegans, GI17509795, Length=249, Percent_Identity=36.144578313253, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17509797, Length=249, Percent_Identity=36.144578313253, Blast_Score=159, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6324082, Length=319, Percent_Identity=30.0940438871473, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI19922218, Length=513, Percent_Identity=32.943469785575, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI19922364, Length=247, Percent_Identity=38.0566801619433, Blast_Score=177, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 54390; Mature: 54259

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFIYNSLGKKKEQFESLYPGLVTMYVCGPTVYGHAHLGHAKSYVSFDVVARWLRHIGF
CEEEEECCCCCHHHHHHHHCCHHHHHEECCCCEECCCHHCHHHHHHHHHHHHHHHHHHCC
RVKYVQNITDVGHLTDDGDDGEDKIERQARTEKTDPMEIAQFYTRSFYEDMDRLGVERPN
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
IAPTATGHIPEQIALIEKLIASEHAYVVNGNVYFSVDSFPGYGKLSGRTDQDAVLSGNRV
CCCCCCCCCHHHHHHHHHHHHCCCCEEEECEEEEEECCCCCCCCCCCCCCCHHHCCCCEE
QLRSEKRNPSDFALWKKAEPGHMMQWHSPWGSGFPGWHVECSAMATKYLGPTIDIHGGGM
EEECCCCCCCCCEEEECCCCCCCEEECCCCCCCCCCCEEEHHHHHHHHCCCEEEECCCCC
ENKFPHHDCEIAQSEAASGKPFVRYWMHNNMVTVNGTKMGKSLKNSVNLKDLFKRVDPVV
CCCCCCCCHHHHHHHCCCCCCEEEEEECCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHH
IRFFILQSHYRSPLDYSETAIRASQTGLEKLHDTMRRLLQALPGSGELNISAFIDRFESA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
MNDDFNTPIAISVLFDFSKSLNSALDQECGLSETALDNAKRFLGMYGTTLLGIIPPEAQP
HCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCC
LTTGMENGEKTLDEVISILLDMRKEAREQKNYPLSDTIRDRLLEAGIEVKDTKDGASWSK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEECCCCCCHHH
VSNR
CCCC
>Mature Secondary Structure 
SLFIYNSLGKKKEQFESLYPGLVTMYVCGPTVYGHAHLGHAKSYVSFDVVARWLRHIGF
EEEEECCCCCHHHHHHHHCCHHHHHEECCCCEECCCHHCHHHHHHHHHHHHHHHHHHCC
RVKYVQNITDVGHLTDDGDDGEDKIERQARTEKTDPMEIAQFYTRSFYEDMDRLGVERPN
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
IAPTATGHIPEQIALIEKLIASEHAYVVNGNVYFSVDSFPGYGKLSGRTDQDAVLSGNRV
CCCCCCCCCHHHHHHHHHHHHCCCCEEEECEEEEEECCCCCCCCCCCCCCCHHHCCCCEE
QLRSEKRNPSDFALWKKAEPGHMMQWHSPWGSGFPGWHVECSAMATKYLGPTIDIHGGGM
EEECCCCCCCCCEEEECCCCCCCEEECCCCCCCCCCCEEEHHHHHHHHCCCEEEECCCCC
ENKFPHHDCEIAQSEAASGKPFVRYWMHNNMVTVNGTKMGKSLKNSVNLKDLFKRVDPVV
CCCCCCCCHHHHHHHCCCCCCEEEEEECCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHH
IRFFILQSHYRSPLDYSETAIRASQTGLEKLHDTMRRLLQALPGSGELNISAFIDRFESA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
MNDDFNTPIAISVLFDFSKSLNSALDQECGLSETALDNAKRFLGMYGTTLLGIIPPEAQP
HCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCC
LTTGMENGEKTLDEVISILLDMRKEAREQKNYPLSDTIRDRLLEAGIEVKDTKDGASWSK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEECCCCCCHHH
VSNR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA