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The map label for this gene is folB [H]

Identifier: 119358066

GI number: 119358066

Start: 2626394

End: 2626771

Strand: Direct

Name: folB [H]

Synonym: Cpha266_2294

Alternate gene names: 119358066

Gene position: 2626394-2626771 (Clockwise)

Preceding gene: 119358064

Following gene: 119358067

Centisome position: 83.81

GC content: 43.12

Gene sequence:

>378_bases
ATGACCAAACGTGCCCATTCATGCATAAGACTCGTTAACATGGTCTTCTATGCCCATCACGGAGTATTGAAAGAGGAACA
TGCCCTGGGCGCCAAATATGAAGTCGATACCGATCTCCACTTTGATTTCTCTCTGGCCGCCAGTCAGGATAAGCTGAAAA
AAACGATTGACTACGGCGAAGCATACGGGAAAATCAAGACCATTCTGACCGAAAAAAACTATTTTCTTATTGAAACGATA
GCCTTTGATATCGCACATGAATTTTTTCTTGCATTTTCCATCCTCGAAGAAATAACCGTGAAAGTAAGAAAGCGCAACCC
GCCAATCAATGGCATCTGTGATTATGCAGAAGCCGTTTATACAGAACGACGCTCCTGA

Upstream 100 bases:

>100_bases
CATATTGGTTCCAATGAGAGGAAATAATCGTTTTTCCTTTTTGATTGACCGCATTTATCATGAACATTGTTAGCTTTCAA
AAAAAACAAAAGAAACGCTC

Downstream 100 bases:

>100_bases
TCCATGCACCCTCAAACCGTTTTTTTAGGAATAGGCTCCAACATAGGAAATCGCCTGCTGCATCTTGAAGAAGCTGTAAG
GCGGCTTGCAGACATTCCCG

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 125; Mature: 124

Protein sequence:

>125_residues
MTKRAHSCIRLVNMVFYAHHGVLKEEHALGAKYEVDTDLHFDFSLAASQDKLKKTIDYGEAYGKIKTILTEKNYFLIETI
AFDIAHEFFLAFSILEEITVKVRKRNPPINGICDYAEAVYTERRS

Sequences:

>Translated_125_residues
MTKRAHSCIRLVNMVFYAHHGVLKEEHALGAKYEVDTDLHFDFSLAASQDKLKKTIDYGEAYGKIKTILTEKNYFLIETI
AFDIAHEFFLAFSILEEITVKVRKRNPPINGICDYAEAVYTERRS
>Mature_124_residues
TKRAHSCIRLVNMVFYAHHGVLKEEHALGAKYEVDTDLHFDFSLAASQDKLKKTIDYGEAYGKIKTILTEKNYFLIETIA
FDIAHEFFLAFSILEEITVKVRKRNPPINGICDYAEAVYTERRS

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 14434; Mature: 14303

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRAHSCIRLVNMVFYAHHGVLKEEHALGAKYEVDTDLHFDFSLAASQDKLKKTIDYGE
CCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCEECCCCCEEEEEECCCHHHHHHHHHHHH
AYGKIKTILTEKNYFLIETIAFDIAHEFFLAFSILEEITVKVRKRNPPINGICDYAEAVY
HHHHHHHEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TERRS
HHCCC
>Mature Secondary Structure 
TKRAHSCIRLVNMVFYAHHGVLKEEHALGAKYEVDTDLHFDFSLAASQDKLKKTIDYGE
CCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCEECCCCCEEEEEECCCHHHHHHHHHHHH
AYGKIKTILTEKNYFLIETIAFDIAHEFFLAFSILEEITVKVRKRNPPINGICDYAEAVY
HHHHHHHEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TERRS
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]