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The map label for this gene is insK [H]

Identifier: 119357904

GI number: 119357904

Start: 2450099

End: 2450965

Strand: Reverse

Name: insK [H]

Synonym: Cpha266_2112

Alternate gene names: 119357904

Gene position: 2450965-2450099 (Counterclockwise)

Preceding gene: 119357905

Following gene: 119357901

Centisome position: 78.21

GC content: 53.06

Gene sequence:

>867_bases
ATGAAAGCGCGTAAAAGCTGGATCAGCGACAAGGGACCGTTGTCGGTATCGACCCAATGTGAACTTGCCGGAGTAACCCG
GTCAGGGTACTACGGGCAAAGCAAAAGCCTCATGCCAAATACTGAAGATCTGGAACTGATGAAACTTATCGACGAGGAGT
ACACCCGACATCCGTTTTATGGAAGCCGGCGGATGAAGCGGGTACTGCTCGCCCAAGGGCGCAAGGTCAACCGGAAACGA
GTACAGCGTCTGATGCGTAACCTGGGGCTTGCTGGTATCGCTCCAGGGCCCAATACCAGCAAGCCGCATCCGCAGCACAA
GATCTATCCATACCTGTTGCGAGGTCTTGTCATTACCAGACCGAATCATGTCTGGTCGACCGATGTGACCTATTGCCGGT
TACCCGGCGGCTTCATGTATCTGACGGCCGTCATCGACTGGTATTCCCGCAAGGTGCTGGCATGGAGGCTTTCGAATTCC
CTGGATAGCAGCTTCTGTGTTGATTGTCTGGAAGAAGCTATCCGCAAGTACGGAATGCCGGAAATCTTCAACACCGATCA
GGGTACTCAGTACACCAGCGAAGCGTTTACCGGCGTACTCAAGAGCCATGACATCCGCATCAGTATGGATGGTCGGGGTC
GGGCGCTGGACAATATCTTCGTCGAACGGCTATGGCGGAACGTCAAGCAAGAAGACCTGTATCTGAAAGGCTATGAGACA
GCGGTCGAAATGATGCGGGGATTAACGGAATATTTCCGTTTTTACAATATCGAGCGGCCTCATCAGTCGCTGGGGTACAA
AACCCCGGACGAGGTATACGAAAGCGCAACAGGTGGCGGTGCTCGTATCGTTGTAGTCGGAAATTAA

Upstream 100 bases:

>100_bases
AGCCGGTCGATCCACTTGCAGATCCGGAAAAGCTTTATGCTGAAATAGGTCGGCTCAAAGTTGAGTTGAGTTGGCTCAAA
AAAAAAGTCGATCCGTACCT

Downstream 100 bases:

>100_bases
AAATCAGCCAATTTCGGAAATTAGCAATCACCCAGGCAGCGGCTTCAGATTACGTCATTTTGCAATGATTTCCTACTCCT
TTTTGAAGTGGTAGTTGCTT

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MKARKSWISDKGPLSVSTQCELAGVTRSGYYGQSKSLMPNTEDLELMKLIDEEYTRHPFYGSRRMKRVLLAQGRKVNRKR
VQRLMRNLGLAGIAPGPNTSKPHPQHKIYPYLLRGLVITRPNHVWSTDVTYCRLPGGFMYLTAVIDWYSRKVLAWRLSNS
LDSSFCVDCLEEAIRKYGMPEIFNTDQGTQYTSEAFTGVLKSHDIRISMDGRGRALDNIFVERLWRNVKQEDLYLKGYET
AVEMMRGLTEYFRFYNIERPHQSLGYKTPDEVYESATGGGARIVVVGN

Sequences:

>Translated_288_residues
MKARKSWISDKGPLSVSTQCELAGVTRSGYYGQSKSLMPNTEDLELMKLIDEEYTRHPFYGSRRMKRVLLAQGRKVNRKR
VQRLMRNLGLAGIAPGPNTSKPHPQHKIYPYLLRGLVITRPNHVWSTDVTYCRLPGGFMYLTAVIDWYSRKVLAWRLSNS
LDSSFCVDCLEEAIRKYGMPEIFNTDQGTQYTSEAFTGVLKSHDIRISMDGRGRALDNIFVERLWRNVKQEDLYLKGYET
AVEMMRGLTEYFRFYNIERPHQSLGYKTPDEVYESATGGGARIVVVGN
>Mature_288_residues
MKARKSWISDKGPLSVSTQCELAGVTRSGYYGQSKSLMPNTEDLELMKLIDEEYTRHPFYGSRRMKRVLLAQGRKVNRKR
VQRLMRNLGLAGIAPGPNTSKPHPQHKIYPYLLRGLVITRPNHVWSTDVTYCRLPGGFMYLTAVIDWYSRKVLAWRLSNS
LDSSFCVDCLEEAIRKYGMPEIFNTDQGTQYTSEAFTGVLKSHDIRISMDGRGRALDNIFVERLWRNVKQEDLYLKGYET
AVEMMRGLTEYFRFYNIERPHQSLGYKTPDEVYESATGGGARIVVVGN

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=228, Percent_Identity=28.9473684210526, Blast_Score=99, Evalue=5e-21,
Organism=Escherichia coli, GI1789981, Length=254, Percent_Identity=33.4645669291339, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788405, Length=275, Percent_Identity=28.7272727272727, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787263, Length=275, Percent_Identity=28.7272727272727, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1786753, Length=275, Percent_Identity=28.7272727272727, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1786570, Length=275, Percent_Identity=28.7272727272727, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1786490, Length=275, Percent_Identity=28.7272727272727, Blast_Score=104, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33085; Mature: 33085

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKARKSWISDKGPLSVSTQCELAGVTRSGYYGQSKSLMPNTEDLELMKLIDEEYTRHPFY
CCCCHHHCCCCCCCEECCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
GSRRMKRVLLAQGRKVNRKRVQRLMRNLGLAGIAPGPNTSKPHPQHKIYPYLLRGLVITR
CHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCHHHHHHHCCCEEC
PNHVWSTDVTYCRLPGGFMYLTAVIDWYSRKVLAWRLSNSLDSSFCVDCLEEAIRKYGMP
CCCEEECCCCEEECCCCHHHHHHHHHHHHHHHHEEHHCCCCCHHHHHHHHHHHHHHCCCC
EIFNTDQGTQYTSEAFTGVLKSHDIRISMDGRGRALDNIFVERLWRNVKQEDLYLKGYET
CCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCEEEHHHHH
AVEMMRGLTEYFRFYNIERPHQSLGYKTPDEVYESATGGGARIVVVGN
HHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHCCCCCCEEEEEECC
>Mature Secondary Structure
MKARKSWISDKGPLSVSTQCELAGVTRSGYYGQSKSLMPNTEDLELMKLIDEEYTRHPFY
CCCCHHHCCCCCCCEECCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
GSRRMKRVLLAQGRKVNRKRVQRLMRNLGLAGIAPGPNTSKPHPQHKIYPYLLRGLVITR
CHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCHHHHHHHCCCEEC
PNHVWSTDVTYCRLPGGFMYLTAVIDWYSRKVLAWRLSNSLDSSFCVDCLEEAIRKYGMP
CCCEEECCCCEEECCCCHHHHHHHHHHHHHHHHEEHHCCCCCHHHHHHHHHHHHHHCCCC
EIFNTDQGTQYTSEAFTGVLKSHDIRISMDGRGRALDNIFVERLWRNVKQEDLYLKGYET
CCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCEEEHHHHH
AVEMMRGLTEYFRFYNIERPHQSLGYKTPDEVYESATGGGARIVVVGN
HHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]