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The map label for this gene is dtd

Identifier: 119357872

GI number: 119357872

Start: 2414394

End: 2414846

Strand: Reverse

Name: dtd

Synonym: Cpha266_2080

Alternate gene names: 119357872

Gene position: 2414846-2414394 (Counterclockwise)

Preceding gene: 119357873

Following gene: 119357871

Centisome position: 77.06

GC content: 54.97

Gene sequence:

>453_bases
ATGAGAGTTATCGTTCAGCGGGTGCTTTCGGCATCGGTTGCGTCCGGTGATGAGAGCGCTGTGCATATCGGGCCTGGTCT
GCTGGTTCTTTCCGGTATTGCGCCTGCGGATGATCAGGCTGCGCTCGGGTGGATGTGCAGGAAAGTTGTCAATCTCAGGA
TTTTTGACGATGAAGCCGGTCGGATGAACCGATCGGTCAAGGATATCGGGGGAGAGATTCTTCTGGTTTCGCAGTTTACG
CTCTACAGCGACGTTTCGAGCGGCAACAGGCCGGGTTTTTCCGGCGCGGCAGGTTATGATATCGCAAAACCGCTGTTTGA
AAAGTTTCATCAGATGGTTCAGCAGGAGATGGAGAGGCCGGTTGCGACCGGTTGGTACGGAGAACATATGCAGGTCGCGC
TCGTCAATGACGGCCCGGTCACGTTAATTATAGACAGCCCCACGCGCTCATGA

Upstream 100 bases:

>100_bases
AAGTTCTAAAAACAAAACCATAAAGGTAGAGGGGCTCGGTGCCGAAGAGGTTGCCCTGCTCCTGCGTCCCTATCTTTGAG
AGGTTATTAACGCCGACAGA

Downstream 100 bases:

>100_bases
AAGCAGTTATTCTTATTCCGGCCAGGCTTGATTCCAGTCGGCTTGAAAAAAAAATGCTCGCTGATCTTCAGGGCGAGCCG
CTCATTGTCCGCACCTGGCG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MRVIVQRVLSASVASGDESAVHIGPGLLVLSGIAPADDQAALGWMCRKVVNLRIFDDEAGRMNRSVKDIGGEILLVSQFT
LYSDVSSGNRPGFSGAAGYDIAKPLFEKFHQMVQQEMERPVATGWYGEHMQVALVNDGPVTLIIDSPTRS

Sequences:

>Translated_150_residues
MRVIVQRVLSASVASGDESAVHIGPGLLVLSGIAPADDQAALGWMCRKVVNLRIFDDEAGRMNRSVKDIGGEILLVSQFT
LYSDVSSGNRPGFSGAAGYDIAKPLFEKFHQMVQQEMERPVATGWYGEHMQVALVNDGPVTLIIDSPTRS
>Mature_150_residues
MRVIVQRVLSASVASGDESAVHIGPGLLVLSGIAPADDQAALGWMCRKVVNLRIFDDEAGRMNRSVKDIGGEILLVSQFT
LYSDVSSGNRPGFSGAAGYDIAKPLFEKFHQMVQQEMERPVATGWYGEHMQVALVNDGPVTLIIDSPTRS

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=150, Percent_Identity=43.3333333333333, Blast_Score=110, Evalue=5e-25,
Organism=Escherichia coli, GI1790320, Length=142, Percent_Identity=44.3661971830986, Blast_Score=117, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI115533292, Length=151, Percent_Identity=36.4238410596026, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=37.8378378378378, Blast_Score=107, Evalue=5e-25,
Organism=Drosophila melanogaster, GI281361569, Length=151, Percent_Identity=40.3973509933775, Blast_Score=116, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_CHLPD (A1BI65)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_912516.1
- ProteinModelPortal:   A1BI65
- SMR:   A1BI65
- STRING:   A1BI65
- GeneID:   4570427
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2080
- NMPDR:   fig|290317.7.peg.2197
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   CLSK2607781
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16203; Mature: 16203

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVIVQRVLSASVASGDESAVHIGPGLLVLSGIAPADDQAALGWMCRKVVNLRIFDDEAG
CHHHHHHHHHHHHCCCCCCEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHEEEECCCCC
RMNRSVKDIGGEILLVSQFTLYSDVSSGNRPGFSGAAGYDIAKPLFEKFHQMVQQEMERP
HHCCHHHHCCCCEEEEEEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
VATGWYGEHMQVALVNDGPVTLIIDSPTRS
CCCCCCCCCEEEEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MRVIVQRVLSASVASGDESAVHIGPGLLVLSGIAPADDQAALGWMCRKVVNLRIFDDEAG
CHHHHHHHHHHHHCCCCCCEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHEEEECCCCC
RMNRSVKDIGGEILLVSQFTLYSDVSSGNRPGFSGAAGYDIAKPLFEKFHQMVQQEMERP
HHCCHHHHCCCCEEEEEEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
VATGWYGEHMQVALVNDGPVTLIIDSPTRS
CCCCCCCCCEEEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA