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The map label for this gene is kdsB

Identifier: 119357871

GI number: 119357871

Start: 2413654

End: 2414397

Strand: Reverse

Name: kdsB

Synonym: Cpha266_2079

Alternate gene names: 119357871

Gene position: 2414397-2413654 (Counterclockwise)

Preceding gene: 119357872

Following gene: 119357869

Centisome position: 77.04

GC content: 55.11

Gene sequence:

>744_bases
ATGAAAGCAGTTATTCTTATTCCGGCCAGGCTTGATTCCAGTCGGCTTGAAAAAAAAATGCTCGCTGATCTTCAGGGCGA
GCCGCTCATTGTCCGCACCTGGCGTCAGGCGCTGAAATCCCGTCTGGCCGACAGGGTCGTTGTTGCTACCGACAACGATG
AAATCGCCTCGGTGCTGCAGGCATACGGAGCGGAGGTGGTGATGACCTCCCCGCATGCGCGGTGCGGAACAGAGAGGATT
GCAGAAGCGGCAAAAAGCATTGAGGGAGATATCTATGTCAACCTGCAGGGCGACGAGCCCCTCATCAGTCCGGAGAACAT
CGATCTTGCACTGGAGCCGTTTTTCACCGAGACCCCTCCCGATTGCTCGACGCTTGTCTTTCCCTTGCTCCCCGAAGATT
TCCGGCAACTGGAAGATATCAACACCGTCAAGGTTGTGATGGATAATGCGGGATACGCCCTCTATTTTTCGCGCAGCCCG
ATACCCTATCAGCGGCAGATCAGTACGAGCACCGAGTGTTATCGCCATATCGGCCTCTATGCGTTCAGGGCCGATGTCCT
TCATGCTTTTGCATCCCTTGCTCCTTCCATGCTCGAACTTGCCGAATCGCTTGAGCAACTCCGTCTTCTCGAAAACGGCT
ACCGGATCCGGTGCGTGAAAACCACCAGGGACGCGCCGGGAGTCAATACGTATGAAGACCTTGAGCTTGTGCGTCAACTG
CTCAGGAACGCACCGGTTCAGTAA

Upstream 100 bases:

>100_bases
TGGAGAGGCCGGTTGCGACCGGTTGGTACGGAGAACATATGCAGGTCGCGCTCGTCAATGACGGCCCGGTCACGTTAATT
ATAGACAGCCCCACGCGCTC

Downstream 100 bases:

>100_bases
CAACCGCGGTTACGCTCCCGTCATGAAACAGCAGCTCCGTGCGATCCTGAAGATGCAGGCACTGTGCGCTGGTAACGACA
GCCCCCTCTTTTTTTACGAG

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MKAVILIPARLDSSRLEKKMLADLQGEPLIVRTWRQALKSRLADRVVVATDNDEIASVLQAYGAEVVMTSPHARCGTERI
AEAAKSIEGDIYVNLQGDEPLISPENIDLALEPFFTETPPDCSTLVFPLLPEDFRQLEDINTVKVVMDNAGYALYFSRSP
IPYQRQISTSTECYRHIGLYAFRADVLHAFASLAPSMLELAESLEQLRLLENGYRIRCVKTTRDAPGVNTYEDLELVRQL
LRNAPVQ

Sequences:

>Translated_247_residues
MKAVILIPARLDSSRLEKKMLADLQGEPLIVRTWRQALKSRLADRVVVATDNDEIASVLQAYGAEVVMTSPHARCGTERI
AEAAKSIEGDIYVNLQGDEPLISPENIDLALEPFFTETPPDCSTLVFPLLPEDFRQLEDINTVKVVMDNAGYALYFSRSP
IPYQRQISTSTECYRHIGLYAFRADVLHAFASLAPSMLELAESLEQLRLLENGYRIRCVKTTRDAPGVNTYEDLELVRQL
LRNAPVQ
>Mature_247_residues
MKAVILIPARLDSSRLEKKMLADLQGEPLIVRTWRQALKSRLADRVVVATDNDEIASVLQAYGAEVVMTSPHARCGTERI
AEAAKSIEGDIYVNLQGDEPLISPENIDLALEPFFTETPPDCSTLVFPLLPEDFRQLEDINTVKVVMDNAGYALYFSRSP
IPYQRQISTSTECYRHIGLYAFRADVLHAFASLAPSMLELAESLEQLRLLENGYRIRCVKTTRDAPGVNTYEDLELVRQL
LRNAPVQ

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=253, Percent_Identity=39.1304347826087, Blast_Score=154, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_CHLPD (A1BI64)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_912515.1
- ProteinModelPortal:   A1BI64
- SMR:   A1BI64
- STRING:   A1BI64
- GeneID:   4570426
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2079
- NMPDR:   fig|290317.7.peg.2196
- eggNOG:   COG1212
- HOGENOM:   HBG637773
- OMA:   IIPARLK
- ProtClustDB:   PRK05450
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 27724; Mature: 27724

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVILIPARLDSSRLEKKMLADLQGEPLIVRTWRQALKSRLADRVVVATDNDEIASVLQ
CCEEEEEECCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCEEEEEECCHHHHHHHH
AYGAEVVMTSPHARCGTERIAEAAKSIEGDIYVNLQGDEPLISPENIDLALEPFFTETPP
HCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEECCCCCCCCC
DCSTLVFPLLPEDFRQLEDINTVKVVMDNAGYALYFSRSPIPYQRQISTSTECYRHIGLY
CHHHEEECCCCHHHHHHHCCCEEEEEEECCCEEEEECCCCCCHHHHCCHHHHHHHHHHHH
AFRADVLHAFASLAPSMLELAESLEQLRLLENGYRIRCVKTTRDAPGVNTYEDLELVRQL
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHH
LRNAPVQ
HHHCCCC
>Mature Secondary Structure
MKAVILIPARLDSSRLEKKMLADLQGEPLIVRTWRQALKSRLADRVVVATDNDEIASVLQ
CCEEEEEECCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCEEEEEECCHHHHHHHH
AYGAEVVMTSPHARCGTERIAEAAKSIEGDIYVNLQGDEPLISPENIDLALEPFFTETPP
HCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEECCCCCCCCC
DCSTLVFPLLPEDFRQLEDINTVKVVMDNAGYALYFSRSPIPYQRQISTSTECYRHIGLY
CHHHEEECCCCHHHHHHHCCCEEEEEEECCCEEEEECCCCCCHHHHCCHHHHHHHHHHHH
AFRADVLHAFASLAPSMLELAESLEQLRLLENGYRIRCVKTTRDAPGVNTYEDLELVRQL
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHH
LRNAPVQ
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA