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The map label for this gene is insK [H]

Identifier: 119357748

GI number: 119357748

Start: 2266321

End: 2267244

Strand: Reverse

Name: insK [H]

Synonym: Cpha266_1954

Alternate gene names: 119357748

Gene position: 2267244-2266321 (Counterclockwise)

Preceding gene: 119357749

Following gene: 119357747

Centisome position: 72.35

GC content: 53.46

Gene sequence:

>924_bases
ATGAAAGCGCGTAAAAGCTGGATCAGCGACAAGGGACCGTTGTCGGTATCGACCCAATGTGAACTTGCCGGAGTAACCCG
GTCAGGGTACTACGGGCAAAGCAAAAGCCTCATGCCAAATACTGAAGATCTGGAACTGATGAAACTTATCGACGAGGAGT
ACACCCGACATCCGTTTTATGGAAGCCGGCGGATGAAGCGGGTACTGCTCGCCCAAGGGCGCAAGGTCAACCGGAAACGA
GTACAGCGTCTGATGCGTAACCTGGGGCTTGCTGGTATCGCTCCAGGGCCCAATACCAGCAAGCCGCATCCGCAGCACAA
GATCTATCCATACCTGTTGCGAGGTCTTGTCATTACCAGACCGAATCATGTCTGGTCGACCGATGTGACCTATTGCCGGT
TACCCGGCGGCTTCATGTATCTGACGGCCGTCATCGACTGGTATTCCCGCAAGGTGCTGGCATGGAGGCTTTCGAATTCC
CTGGATAGCAGCTTCTGTGTTGATTGTCTGGAAGAAGCTATCCGCAAGTACGGAATGCCGGAAATCTTCAACACCGATCA
GGGTACTCAGTACACCAGCGAAGCGTTTACCGGCGTACTCAAGAGCCATGACATCCGCATCAGTATGGATGGTCGGGGTC
GGGCGCTGGACAATATCTTCGTCGAACGGCTATGGCGGAACGTCAAGCAAGAAGACCTGTATCTGAAAGGCTATGAGACA
GCGGTCGAAATGATGCGGGGATTAACGGAATATTTCCGTTTTTACAATATCGAGCGGCCTCATCAGTCGCTGGGGTACAA
AACCCCGGACGAGGTATACGAAAGCGCAACAGGTGGCGGTGCTCGTATCGTTGACAAGTTCTTTCAAAAGAGTGTCTCCG
AAGGGTCGTCGGAGGCTACAGGGCCGCAACAGGAAGCGGCATAA

Upstream 100 bases:

>100_bases
AGCCGGTCGATCCACTTGCAGATCCGGAAAAGCTTTATGCTGAAATAGGTCGGCTCAAAGTTGAGTTGAGTTGGCTCAAA
AAAAAAGTCGATCCGTACCT

Downstream 100 bases:

>100_bases
ACAACCGGCGGGTTGCCACCTTAAATTCGACCTTATTTTGTCTGGTCGATAGGGTCCACTTCAGGATGAAGAGGAAGAGT
TTGCCCACGAATTGACACGA

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKARKSWISDKGPLSVSTQCELAGVTRSGYYGQSKSLMPNTEDLELMKLIDEEYTRHPFYGSRRMKRVLLAQGRKVNRKR
VQRLMRNLGLAGIAPGPNTSKPHPQHKIYPYLLRGLVITRPNHVWSTDVTYCRLPGGFMYLTAVIDWYSRKVLAWRLSNS
LDSSFCVDCLEEAIRKYGMPEIFNTDQGTQYTSEAFTGVLKSHDIRISMDGRGRALDNIFVERLWRNVKQEDLYLKGYET
AVEMMRGLTEYFRFYNIERPHQSLGYKTPDEVYESATGGGARIVDKFFQKSVSEGSSEATGPQQEAA

Sequences:

>Translated_307_residues
MKARKSWISDKGPLSVSTQCELAGVTRSGYYGQSKSLMPNTEDLELMKLIDEEYTRHPFYGSRRMKRVLLAQGRKVNRKR
VQRLMRNLGLAGIAPGPNTSKPHPQHKIYPYLLRGLVITRPNHVWSTDVTYCRLPGGFMYLTAVIDWYSRKVLAWRLSNS
LDSSFCVDCLEEAIRKYGMPEIFNTDQGTQYTSEAFTGVLKSHDIRISMDGRGRALDNIFVERLWRNVKQEDLYLKGYET
AVEMMRGLTEYFRFYNIERPHQSLGYKTPDEVYESATGGGARIVDKFFQKSVSEGSSEATGPQQEAA
>Mature_307_residues
MKARKSWISDKGPLSVSTQCELAGVTRSGYYGQSKSLMPNTEDLELMKLIDEEYTRHPFYGSRRMKRVLLAQGRKVNRKR
VQRLMRNLGLAGIAPGPNTSKPHPQHKIYPYLLRGLVITRPNHVWSTDVTYCRLPGGFMYLTAVIDWYSRKVLAWRLSNS
LDSSFCVDCLEEAIRKYGMPEIFNTDQGTQYTSEAFTGVLKSHDIRISMDGRGRALDNIFVERLWRNVKQEDLYLKGYET
AVEMMRGLTEYFRFYNIERPHQSLGYKTPDEVYESATGGGARIVDKFFQKSVSEGSSEATGPQQEAA

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=228, Percent_Identity=28.9473684210526, Blast_Score=99, Evalue=4e-21,
Organism=Escherichia coli, GI1789981, Length=254, Percent_Identity=33.4645669291339, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788405, Length=275, Percent_Identity=28.7272727272727, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787263, Length=275, Percent_Identity=28.7272727272727, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786753, Length=275, Percent_Identity=28.7272727272727, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786570, Length=275, Percent_Identity=28.7272727272727, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786490, Length=275, Percent_Identity=28.7272727272727, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 35127; Mature: 35127

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKARKSWISDKGPLSVSTQCELAGVTRSGYYGQSKSLMPNTEDLELMKLIDEEYTRHPFY
CCCCHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
GSRRMKRVLLAQGRKVNRKRVQRLMRNLGLAGIAPGPNTSKPHPQHKIYPYLLRGLVITR
CHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEC
PNHVWSTDVTYCRLPGGFMYLTAVIDWYSRKVLAWRLSNSLDSSFCVDCLEEAIRKYGMP
CCCEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
EIFNTDQGTQYTSEAFTGVLKSHDIRISMDGRGRALDNIFVERLWRNVKQEDLYLKGYET
CCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCEEEHHHHH
AVEMMRGLTEYFRFYNIERPHQSLGYKTPDEVYESATGGGARIVDKFFQKSVSEGSSEAT
HHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCC
GPQQEAA
CCHHCCC
>Mature Secondary Structure
MKARKSWISDKGPLSVSTQCELAGVTRSGYYGQSKSLMPNTEDLELMKLIDEEYTRHPFY
CCCCHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
GSRRMKRVLLAQGRKVNRKRVQRLMRNLGLAGIAPGPNTSKPHPQHKIYPYLLRGLVITR
CHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEC
PNHVWSTDVTYCRLPGGFMYLTAVIDWYSRKVLAWRLSNSLDSSFCVDCLEEAIRKYGMP
CCCEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
EIFNTDQGTQYTSEAFTGVLKSHDIRISMDGRGRALDNIFVERLWRNVKQEDLYLKGYET
CCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCEEEHHHHH
AVEMMRGLTEYFRFYNIERPHQSLGYKTPDEVYESATGGGARIVDKFFQKSVSEGSSEAT
HHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCC
GPQQEAA
CCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]