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The map label for this gene is trpB-1 [H]

Identifier: 119357739

GI number: 119357739

Start: 2253049

End: 2254248

Strand: Direct

Name: trpB-1 [H]

Synonym: Cpha266_1943

Alternate gene names: 119357739

Gene position: 2253049-2254248 (Clockwise)

Preceding gene: 119357737

Following gene: 119357740

Centisome position: 71.89

GC content: 52.67

Gene sequence:

>1200_bases
ATGGTGCCGTTTCACTATTCAGTTCCTGATTCAAAAGGGCATTTCGGTAAATTCGGCGGGAAATTTATCCCGGAAACCCT
TATAAAAAACGCAGCCGATCTTGAGCTCGAATACAGCCGGGCAAAGAATGACCCGGTTTTTCAGACAAGGCTTGCAACGC
TGCTGCGTGACTATGTCGGAAGACCTACCCCGCTCTACCTTGCCGAAAGATTGAGCGGAATGCTCCAGGGAGCGCGCATC
TACCTGAAACGTGAAGACCTCTGTCACACAGGCGCACACAAAATCAATAATGCGCTCGGGCAGGTGCTGCTCGCTGAAAG
AATGGGCAAAAAACGGGTTATCGCCGAAACCGGAGCCGGCCAGCACGGCGTAGCCACCGCTACGGTCTGCGCCCTGTTCG
GCATCTCATGCGTTGTCTACATGGGCGAAGAAGATATCCGCCGCCAGTCGCCGAATGTTGCTCGAATGAAACTGCTCGGC
GCTGAAGTCAGACCTGTCGGTTCAGGCTCGAAAACACTGAAAGACGCAACAAGCGAAGCGATACGGGACTGGATGAACAA
CCCTGAAGATACCTTTTACATTATCGGCTCCGTTGTGGGTATGCACCCTTATCCCATGATAGTAAGGGATTTTCAGTCGG
TCATCGGCCGCGAAACCAGAACGCAGGTTCTCGAACAGGCAGGAAAGCTCCCCGATGTCATCACAGCCTGCGTCGGTGGA
GGAAGCAATGCCATAGGAATCTTTCATGAATTTCTTCCGGACGTTCCCGGCGTTGAACTGGTTGGCGTTGAAGCAGCCGG
AGAAGGACTTCAGGGACGTCATGCCGCATCACTCACCATGGGTAAAACCGGCGTACTGCACGGCGCCATGACAAAACTGC
TGCAGGATGAAGACGGCCAGATCCTTGAAGCGCACTCCATTTCAGCCGGACTCGATTATCCGGGAGTAGGACCTGAACAC
TGCTATCTGCAACGAAAAGGTCTGGTCAGCTATACATCGACTACAGACAAAGAAGCACTTGAGGCGCTTAAAACACTCGC
AGCAACCGAGGGAATCATCTGCGCGCTTGAATCAGCCCATGCCGTACACTATGCCATAAAAAGAGCGCCAGAGATGCCGA
AAGATGCCATTCTTGTTGTAAACCTCTCCGGAAGGGGCGACAAGGATATGGAAACAATAATGCAGAGTATCCCTCTCTGA

Upstream 100 bases:

>100_bases
TTTTATTGCTGTATGACGATGATTTTCTGCGGGTATAAACTTCCAGAAAGAAAAGCAAAACAACTGCTCGATTACCTTCT
ACTCATTTTTTTATTATTTC

Downstream 100 bases:

>100_bases
TACAACAACTTGTCTCTTTTGTGCAACCATAAAAAAAATCTTTCAAGAGGGTTGCACAAAATCGAAATATCTTTATATTT
ATGGCTCATTAACGCGGGAA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MVPFHYSVPDSKGHFGKFGGKFIPETLIKNAADLELEYSRAKNDPVFQTRLATLLRDYVGRPTPLYLAERLSGMLQGARI
YLKREDLCHTGAHKINNALGQVLLAERMGKKRVIAETGAGQHGVATATVCALFGISCVVYMGEEDIRRQSPNVARMKLLG
AEVRPVGSGSKTLKDATSEAIRDWMNNPEDTFYIIGSVVGMHPYPMIVRDFQSVIGRETRTQVLEQAGKLPDVITACVGG
GSNAIGIFHEFLPDVPGVELVGVEAAGEGLQGRHAASLTMGKTGVLHGAMTKLLQDEDGQILEAHSISAGLDYPGVGPEH
CYLQRKGLVSYTSTTDKEALEALKTLAATEGIICALESAHAVHYAIKRAPEMPKDAILVVNLSGRGDKDMETIMQSIPL

Sequences:

>Translated_399_residues
MVPFHYSVPDSKGHFGKFGGKFIPETLIKNAADLELEYSRAKNDPVFQTRLATLLRDYVGRPTPLYLAERLSGMLQGARI
YLKREDLCHTGAHKINNALGQVLLAERMGKKRVIAETGAGQHGVATATVCALFGISCVVYMGEEDIRRQSPNVARMKLLG
AEVRPVGSGSKTLKDATSEAIRDWMNNPEDTFYIIGSVVGMHPYPMIVRDFQSVIGRETRTQVLEQAGKLPDVITACVGG
GSNAIGIFHEFLPDVPGVELVGVEAAGEGLQGRHAASLTMGKTGVLHGAMTKLLQDEDGQILEAHSISAGLDYPGVGPEH
CYLQRKGLVSYTSTTDKEALEALKTLAATEGIICALESAHAVHYAIKRAPEMPKDAILVVNLSGRGDKDMETIMQSIPL
>Mature_399_residues
MVPFHYSVPDSKGHFGKFGGKFIPETLIKNAADLELEYSRAKNDPVFQTRLATLLRDYVGRPTPLYLAERLSGMLQGARI
YLKREDLCHTGAHKINNALGQVLLAERMGKKRVIAETGAGQHGVATATVCALFGISCVVYMGEEDIRRQSPNVARMKLLG
AEVRPVGSGSKTLKDATSEAIRDWMNNPEDTFYIIGSVVGMHPYPMIVRDFQSVIGRETRTQVLEQAGKLPDVITACVGG
GSNAIGIFHEFLPDVPGVELVGVEAAGEGLQGRHAASLTMGKTGVLHGAMTKLLQDEDGQILEAHSISAGLDYPGVGPEH
CYLQRKGLVSYTSTTDKEALEALKTLAATEGIICALESAHAVHYAIKRAPEMPKDAILVVNLSGRGDKDMETIMQSIPL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=382, Percent_Identity=54.1884816753927, Blast_Score=416, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6321412, Length=386, Percent_Identity=55.1813471502591, Blast_Score=431, Evalue=1e-121,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43078; Mature: 43078

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPFHYSVPDSKGHFGKFGGKFIPETLIKNAADLELEYSRAKNDPVFQTRLATLLRDYVG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEHHHCCCCCHHHHHHHHHHHHHCC
RPTPLYLAERLSGMLQGARIYLKREDLCHTGAHKINNALGQVLLAERMGKKRVIAETGAG
CCCHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
QHGVATATVCALFGISCVVYMGEEDIRRQSPNVARMKLLGAEVRPVGSGSKTLKDATSEA
CCCHHHHHHHHHHHHHHEEEECCHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
IRDWMNNPEDTFYIIGSVVGMHPYPMIVRDFQSVIGRETRTQVLEQAGKLPDVITACVGG
HHHHHCCCCCEEEEEEHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCC
GSNAIGIFHEFLPDVPGVELVGVEAAGEGLQGRHAASLTMGKTGVLHGAMTKLLQDEDGQ
CCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHEEECCCHHHHHHHHHHHHCCCCCC
ILEAHSISAGLDYPGVGPEHCYLQRKGLVSYTSTTDKEALEALKTLAATEGIICALESAH
EEEECCCCCCCCCCCCCCHHHHHHHCCCEEECCCCCHHHHHHHHHHHHCCCCEEEEHHHH
AVHYAIKRAPEMPKDAILVVNLSGRGDKDMETIMQSIPL
HHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MVPFHYSVPDSKGHFGKFGGKFIPETLIKNAADLELEYSRAKNDPVFQTRLATLLRDYVG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEHHHCCCCCHHHHHHHHHHHHHCC
RPTPLYLAERLSGMLQGARIYLKREDLCHTGAHKINNALGQVLLAERMGKKRVIAETGAG
CCCHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
QHGVATATVCALFGISCVVYMGEEDIRRQSPNVARMKLLGAEVRPVGSGSKTLKDATSEA
CCCHHHHHHHHHHHHHHEEEECCHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
IRDWMNNPEDTFYIIGSVVGMHPYPMIVRDFQSVIGRETRTQVLEQAGKLPDVITACVGG
HHHHHCCCCCEEEEEEHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCC
GSNAIGIFHEFLPDVPGVELVGVEAAGEGLQGRHAASLTMGKTGVLHGAMTKLLQDEDGQ
CCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHEEECCCHHHHHHHHHHHHCCCCCC
ILEAHSISAGLDYPGVGPEHCYLQRKGLVSYTSTTDKEALEALKTLAATEGIICALESAH
EEEECCCCCCCCCCCCCCHHHHHHHCCCEEECCCCCHHHHHHHHHHHHCCCCEEEEHHHH
AVHYAIKRAPEMPKDAILVVNLSGRGDKDMETIMQSIPL
HHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]