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The map label for this gene is acoC [H]

Identifier: 119357737

GI number: 119357737

Start: 2249262

End: 2250137

Strand: Direct

Name: acoC [H]

Synonym: Cpha266_1941

Alternate gene names: 119357737

Gene position: 2249262-2250137 (Clockwise)

Preceding gene: 119357734

Following gene: 119357739

Centisome position: 71.77

GC content: 48.86

Gene sequence:

>876_bases
ATGATGACATCCTCCATCCGCGACAACTATTTTTTATGGCAGCTCTCGCCAGAACATGAAGCCAAAATCCGATATCAGGA
ATTCGGCTGTGAAGAGAGCCAGAAAACACCGCTCCTTTTCATCCATGGTTACGGGGGGATGATCGAACATTGGGATAAAA
ATATCCCGGATTTCATCAACACGCATAAAATTTACGCAATAGACCTCATTGGATTCGGCAAGTCACAAAAACCCAACGTC
CGATACAGCCTGGAACTTTTTGCCGCTCAGATTGAAGCCTTTCTCTACCTGAAAAAACTTGAAAAAGTTATCATAGTCGG
TCACTCGATGGGAGCTGCAAGCGCACTCTATTATGCTCATCTCAGGCCGAAAAAGGTTCAGGCACTGGTGCTCGCAAACC
CTTCGGGGCTCTATGCGGGAAGCATGGACGGCGTAACAAAGATTTTTTTCGGGCTTGTCGGATCGCCTCTGATCGGCGAA
GTACTGTTCGGTGCTTTTGCAAATCCGGTAGGCGTCAGCCAAAGCCTTTTGCCGACCTACTACAATCAAAGCATGGTCGA
CATGAACCTTATCAACCAGTTTACTCGGCCTCTTCAGGACAAGGGTGCAATCTGGTCATATCTCTCACCATCACGCAGAC
CTCAGGATTTCACGCTTGACCACCTTGAGAAACCCTGCCGCTTCAAAGGCAAGGCTTTTCTTGTATGGGGGGCCGAAGAC
AGCGCTCTTCCTCCGCATAAAATCATACCGGAATTTCAGCAACTCCTGCCGCAGGCCGGAGCGTTTATCATACCTCAGGC
ATCTCACTGCATTCACCACGATGCCTACAAAGCATTTAACGAACGACTGCTCCGGATTCTTGAGACGCTTGTCTGA

Upstream 100 bases:

>100_bases
TGAAAACCCGCTTTCTATGTTTACTATTAATCCGGATGTGTTATAATAAGTTTGCTGGGAACGTTTTTTGCTGTTTCATC
TGTGCACTTTACTGTTTTTC

Downstream 100 bases:

>100_bases
CAACATCCCGGTCAATTGGTCCAACTGCTGCTTGATCCACTGGTTTTGAACCGGATATCCTGCAACAGGGAAGCTTTCAG
ACCAATCTGAAAGGAATAGC

Product: alpha/beta hydrolase fold

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MMTSSIRDNYFLWQLSPEHEAKIRYQEFGCEESQKTPLLFIHGYGGMIEHWDKNIPDFINTHKIYAIDLIGFGKSQKPNV
RYSLELFAAQIEAFLYLKKLEKVIIVGHSMGAASALYYAHLRPKKVQALVLANPSGLYAGSMDGVTKIFFGLVGSPLIGE
VLFGAFANPVGVSQSLLPTYYNQSMVDMNLINQFTRPLQDKGAIWSYLSPSRRPQDFTLDHLEKPCRFKGKAFLVWGAED
SALPPHKIIPEFQQLLPQAGAFIIPQASHCIHHDAYKAFNERLLRILETLV

Sequences:

>Translated_291_residues
MMTSSIRDNYFLWQLSPEHEAKIRYQEFGCEESQKTPLLFIHGYGGMIEHWDKNIPDFINTHKIYAIDLIGFGKSQKPNV
RYSLELFAAQIEAFLYLKKLEKVIIVGHSMGAASALYYAHLRPKKVQALVLANPSGLYAGSMDGVTKIFFGLVGSPLIGE
VLFGAFANPVGVSQSLLPTYYNQSMVDMNLINQFTRPLQDKGAIWSYLSPSRRPQDFTLDHLEKPCRFKGKAFLVWGAED
SALPPHKIIPEFQQLLPQAGAFIIPQASHCIHHDAYKAFNERLLRILETLV
>Mature_291_residues
MMTSSIRDNYFLWQLSPEHEAKIRYQEFGCEESQKTPLLFIHGYGGMIEHWDKNIPDFINTHKIYAIDLIGFGKSQKPNV
RYSLELFAAQIEAFLYLKKLEKVIIVGHSMGAASALYYAHLRPKKVQALVLANPSGLYAGSMDGVTKIFFGLVGSPLIGE
VLFGAFANPVGVSQSLLPTYYNQSMVDMNLINQFTRPLQDKGAIWSYLSPSRRPQDFTLDHLEKPCRFKGKAFLVWGAED
SALPPHKIIPEFQQLLPQAGAFIIPQASHCIHHDAYKAFNERLLRILETLV

Specific function: Unknown

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI50658087, Length=123, Percent_Identity=28.4552845528455, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI32566936, Length=130, Percent_Identity=33.0769230769231, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17558492, Length=130, Percent_Identity=33.0769230769231, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25146278, Length=114, Percent_Identity=34.2105263157895, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24586385, Length=110, Percent_Identity=33.6363636363636, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24586387, Length=110, Percent_Identity=33.6363636363636, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24586391, Length=110, Percent_Identity=33.6363636363636, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24586389, Length=110, Percent_Identity=33.6363636363636, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 32905; Mature: 32905

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTSSIRDNYFLWQLSPEHEAKIRYQEFGCEESQKTPLLFIHGYGGMIEHWDKNIPDFIN
CCCCCCCCCEEEEEECCCCCCEEEHHHCCCCCCCCCCEEEEECCCCHHHHHCCCCCHHHC
THKIYAIDLIGFGKSQKPNVRYSLELFAAQIEAFLYLKKLEKVIIVGHSMGAASALYYAH
CCEEEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHH
LRPKKVQALVLANPSGLYAGSMDGVTKIFFGLVGSPLIGEVLFGAFANPVGVSQSLLPTY
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHH
YNQSMVDMNLINQFTRPLQDKGAIWSYLSPSRRPQDFTLDHLEKPCRFKGKAFLVWGAED
HCCHHHHHHHHHHHHHCHHHCCCEEHHCCCCCCCCCCCHHHHCCCCCCCCCEEEEECCCC
SALPPHKIIPEFQQLLPQAGAFIIPQASHCIHHDAYKAFNERLLRILETLV
CCCCCHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MMTSSIRDNYFLWQLSPEHEAKIRYQEFGCEESQKTPLLFIHGYGGMIEHWDKNIPDFIN
CCCCCCCCCEEEEEECCCCCCEEEHHHCCCCCCCCCCEEEEECCCCHHHHHCCCCCHHHC
THKIYAIDLIGFGKSQKPNVRYSLELFAAQIEAFLYLKKLEKVIIVGHSMGAASALYYAH
CCEEEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHH
LRPKKVQALVLANPSGLYAGSMDGVTKIFFGLVGSPLIGEVLFGAFANPVGVSQSLLPTY
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHH
YNQSMVDMNLINQFTRPLQDKGAIWSYLSPSRRPQDFTLDHLEKPCRFKGKAFLVWGAED
HCCHHHHHHHHHHHHHCHHHCCCEEHHCCCCCCCCCCCHHHHCCCCCCCCCEEEEECCCC
SALPPHKIIPEFQQLLPQAGAFIIPQASHCIHHDAYKAFNERLLRILETLV
CCCCCHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7813883 [H]