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The map label for this gene is add [H]

Identifier: 119357712

GI number: 119357712

Start: 2223447

End: 2224532

Strand: Direct

Name: add [H]

Synonym: Cpha266_1916

Alternate gene names: 119357712

Gene position: 2223447-2224532 (Clockwise)

Preceding gene: 119357711

Following gene: 119357713

Centisome position: 70.95

GC content: 51.1

Gene sequence:

>1086_bases
ATGAACCTATTGCCGGGATTTGCCTACATTGAAATGGAAAGCATTTCAAACCTCACTCCCTTGGTAATGAAAACACTTGC
AGGGTTTATTGCCGGCATCCCGAAAGCCGAACTGCATCTGCATATCGAAGGAACGCTTGAACCGGAGATGATGCTTGCCC
TTGGCGAGCGTAACGGCGTTCCGCTTCCCTATCCTGACGCTGATGCTGCAAAGAGTGCATACCACTTCAGCGATCTGCAA
TCGTTTCTCGATATCTACTACCGGGCAACGGCTGTCCTTGTTACCGAACAGGATTTTTACGATCTGACCATTGCCTACCT
GCAGAAAGCCGTTTCCCGGAAGGTCTGCCATGCGGAGATCTTTTTTGATCCGCAATCGCATATCGCAAGGGGAGTTCCTT
TTGAAACGGTTGTTGGCGGAATCGGTCAGGCGCTTTCCGACGCAAACGGCGGACTTGGTATTTCAACAAAACTGATCATG
TGCATTCTGCGACACCTCAGCGAAGAGGATGGCAACGCTGTACTTGAACAGGCGGTTCGATGGAAGCGATGGATCAGCGG
CATCGGACTTGACTCCTCGGAGAAAGGCAATCCTCCGGGAAAATTCCGCGAGCTTTTTGCCAAGGCTCGCCACTACGGGT
TTTTCACGGTTGCCCATGCCGGCGAGGAGGGCAATGCCTCTTCTATCAGCGAAGCGCTCGACGCTCTTCATGTCATCCGG
ATTGACCATGGCGTACACTGTATGGAAGACCCTGTTCTGGTTGAAAGGCTGCGCCTTGACCGGATTCCCCTGACGATATG
CCCCCTCTCGAACGTCAGGCTCAACGTATTCGGCTCAATGCGGGAGCACAACCTGAAAACCATGCTTGACGCGGGTCTCT
GTGTCACCATCAACTCCGATGACCCGGCTTATTTCGGCGGTTATGTGAATGAAAACTATCTGGCCGCGGCAGAAGCGCTC
AATCTTGACCGTAACGATATTATCCGGCTTGCCAGAAATTCATTTGAAGCCTCTGTATTAAGCAATGTCCAGAAAAAACT
CTACCTACAGAAACTGGATCATTACGTAGACTCGTTTATTCAGTAA

Upstream 100 bases:

>100_bases
AAGTAATAAACCCCTGGACTTCATTCACTTCATACCCATTGACGAATACCAATTCACGAACATAAAGCTGATTCCACTCA
CCTGATATCTGCAATTCGGC

Downstream 100 bases:

>100_bases
CCCTGATTATCACGATGAACCCGAATTACAACGCCGTTACCGAGTTTATTTCGGCTGAACGTCTCCACAACCGCATCTGC
GAACTGGGATGCGATATATC

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MNLLPGFAYIEMESISNLTPLVMKTLAGFIAGIPKAELHLHIEGTLEPEMMLALGERNGVPLPYPDADAAKSAYHFSDLQ
SFLDIYYRATAVLVTEQDFYDLTIAYLQKAVSRKVCHAEIFFDPQSHIARGVPFETVVGGIGQALSDANGGLGISTKLIM
CILRHLSEEDGNAVLEQAVRWKRWISGIGLDSSEKGNPPGKFRELFAKARHYGFFTVAHAGEEGNASSISEALDALHVIR
IDHGVHCMEDPVLVERLRLDRIPLTICPLSNVRLNVFGSMREHNLKTMLDAGLCVTINSDDPAYFGGYVNENYLAAAEAL
NLDRNDIIRLARNSFEASVLSNVQKKLYLQKLDHYVDSFIQ

Sequences:

>Translated_361_residues
MNLLPGFAYIEMESISNLTPLVMKTLAGFIAGIPKAELHLHIEGTLEPEMMLALGERNGVPLPYPDADAAKSAYHFSDLQ
SFLDIYYRATAVLVTEQDFYDLTIAYLQKAVSRKVCHAEIFFDPQSHIARGVPFETVVGGIGQALSDANGGLGISTKLIM
CILRHLSEEDGNAVLEQAVRWKRWISGIGLDSSEKGNPPGKFRELFAKARHYGFFTVAHAGEEGNASSISEALDALHVIR
IDHGVHCMEDPVLVERLRLDRIPLTICPLSNVRLNVFGSMREHNLKTMLDAGLCVTINSDDPAYFGGYVNENYLAAAEAL
NLDRNDIIRLARNSFEASVLSNVQKKLYLQKLDHYVDSFIQ
>Mature_361_residues
MNLLPGFAYIEMESISNLTPLVMKTLAGFIAGIPKAELHLHIEGTLEPEMMLALGERNGVPLPYPDADAAKSAYHFSDLQ
SFLDIYYRATAVLVTEQDFYDLTIAYLQKAVSRKVCHAEIFFDPQSHIARGVPFETVVGGIGQALSDANGGLGISTKLIM
CILRHLSEEDGNAVLEQAVRWKRWISGIGLDSSEKGNPPGKFRELFAKARHYGFFTVAHAGEEGNASSISEALDALHVIR
IDHGVHCMEDPVLVERLRLDRIPLTICPLSNVRLNVFGSMREHNLKTMLDAGLCVTINSDDPAYFGGYVNENYLAAAEAL
NLDRNDIIRLARNSFEASVLSNVQKKLYLQKLDHYVDSFIQ

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=339, Percent_Identity=24.7787610619469, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1787910, Length=325, Percent_Identity=27.3846153846154, Blast_Score=122, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6324188, Length=340, Percent_Identity=42.6470588235294, Blast_Score=270, Evalue=3e-73,
Organism=Drosophila melanogaster, GI24645260, Length=348, Percent_Identity=26.1494252873563, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 39995; Mature: 39995

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLPGFAYIEMESISNLTPLVMKTLAGFIAGIPKAELHLHIEGTLEPEMMLALGERNGV
CCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHEEECCCCCC
PLPYPDADAAKSAYHFSDLQSFLDIYYRATAVLVTEQDFYDLTIAYLQKAVSRKVCHAEI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHEEEE
FFDPQSHIARGVPFETVVGGIGQALSDANGGLGISTKLIMCILRHLSEEDGNAVLEQAVR
EECCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
WKRWISGIGLDSSEKGNPPGKFRELFAKARHYGFFTVAHAGEEGNASSISEALDALHVIR
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHEE
IDHGVHCMEDPVLVERLRLDRIPLTICPLSNVRLNVFGSMREHNLKTMLDAGLCVTINSD
ECCCCCCCCCHHHHHHHHHCCCCEEEECCCCCEEEEECCHHHHHHHHHHCCCEEEEECCC
DPAYFGGYVNENYLAAAEALNLDRNDIIRLARNSFEASVLSNVQKKLYLQKLDHYVDSFI
CCCEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
Q
C
>Mature Secondary Structure
MNLLPGFAYIEMESISNLTPLVMKTLAGFIAGIPKAELHLHIEGTLEPEMMLALGERNGV
CCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHEEECCCCCC
PLPYPDADAAKSAYHFSDLQSFLDIYYRATAVLVTEQDFYDLTIAYLQKAVSRKVCHAEI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHEEEE
FFDPQSHIARGVPFETVVGGIGQALSDANGGLGISTKLIMCILRHLSEEDGNAVLEQAVR
EECCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
WKRWISGIGLDSSEKGNPPGKFRELFAKARHYGFFTVAHAGEEGNASSISEALDALHVIR
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHEE
IDHGVHCMEDPVLVERLRLDRIPLTICPLSNVRLNVFGSMREHNLKTMLDAGLCVTINSD
ECCCCCCCCCHHHHHHHHHCCCCEEEECCCCCEEEEECCHHHHHHHHHHCCCEEEEECCC
DPAYFGGYVNENYLAAAEALNLDRNDIIRLARNSFEASVLSNVQKKLYLQKLDHYVDSFI
CCCEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA