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The map label for this gene is yhfN [H]

Identifier: 119357698

GI number: 119357698

Start: 2208815

End: 2210074

Strand: Reverse

Name: yhfN [H]

Synonym: Cpha266_1902

Alternate gene names: 119357698

Gene position: 2210074-2208815 (Counterclockwise)

Preceding gene: 119357699

Following gene: 119357697

Centisome position: 70.52

GC content: 49.05

Gene sequence:

>1260_bases
ATGATGAATGGTTTCGGACAGGTTGTTTTGTTTACCCTTGTATTGACTTTTTTCCTCAAGCTTATTGCTGATCTGCTGAA
CCTCCGGGCTTCCGAGAGCGGGCTTCCGCCGGAGTTTCAGGGGGTGTATGAAGAGGATGCCTACAGGAAATCCCAGGACT
ATCTGCGGGCAACAACCCGTTTTTCGCTTATCGGGGCTTTTGTCGATCTTCTTTTTCTGCTTGTTTTCTGGTTTGCCGGA
GGGTTCAATATGCTCGACCAGCTTTTGCGCGCACAGGGATATAACACGGTGCTTACAGGCGTGCTCTATATCGGCGCTCT
CTTGCTCCTGCAGGGGATTCTCGGCCTTCCCTTTACCCTTTACAGGACATTTGTTATCGAGGAGAGGTTTGGATTCAACA
AAACCACACCGAAAGTTTTTGTTGCTGATCTCCTGAAAACCCTTTTTCTTGCCCTGCTCATCGGTACTCCCGTTCTTGCC
GCTCTGCTCTGGTTTTTTGAACAGGCAGGCCCGTTTGGATGGCTCTGGGCCTGGGGCGGGTTGACGCTCTTCACCCTTCT
CTTGCAGTATGTCGCTCCTGCCTGGATCATGCCGATTTTCAACAAGTTTGTTCCGCTTGAAGAAGGCGAGCTGAACAATG
CCATTATGCAATATGCCCGAACGGTCGGATTTCCGCTAACCGGTATTTACGTGATTGATGGGTCGAAGCGATCATCGAAA
GCAAATGCGTTTTTTACCGGATTCGGCAAACGCAAGAGAATTGCCCTGTTTGATACGCTTGTCAGCAACCATAGCGTCAG
TGAGCTTGTTGCTGTGCTTGCGCACGAAATAGGTCATTACAAGAAAAAGCATGTGCTCATCAATATGGTGCTCAGCATGG
TGAATCTCGGTGTTGTCTTTTATCTCCTCTCGGTGTTCATGAACAATCCTGATCTCTTCAGTGCTTTTTTCATGCAGGAT
ATTTCAGTCTACGGCAGCCTTGTTTTTTTCCTTCTGCTCTACAGTCCGGTTGAGTTCGTTCTTTCCATTCTGCTTCAGGC
GCTGTCGCGCAAGCATGAGTATGAGGCCGACAGCTTTGCCGTATCAACATACAGCGACGGATTCGCGCTCGGAGAGGCTC
TTAAAAAGCTTTCGCGCAGCAATCTTTCAAACCTGACGCCTCATGCGCTCTATGTTTTTCTCAACTATTCGCATCCTCCG
GTTGTGCAGCGTATCAGACGAATAAATGAACATCCTGCCCCCGGTCATCTCAACCATTGA

Upstream 100 bases:

>100_bases
TGGATGTTATAAATGGGGAAGCTTGTTATCAGACAAGGGAATCGGGGTTGTTCATGGTGCTTGTACAGAGAGAATGTTTT
TTTATTAATGAGGTGTGGTT

Downstream 100 bases:

>100_bases
TTGTAACCAAAGCGTGTTATGATGGATTTCCAGTATCGCATGCCCCCGGAGTGGGCTTGTCACAAAGCCACCTGGCTTTC
CTGGCCGCACAAACGTGAAT

Product: Ste24 endopeptidase

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MMNGFGQVVLFTLVLTFFLKLIADLLNLRASESGLPPEFQGVYEEDAYRKSQDYLRATTRFSLIGAFVDLLFLLVFWFAG
GFNMLDQLLRAQGYNTVLTGVLYIGALLLLQGILGLPFTLYRTFVIEERFGFNKTTPKVFVADLLKTLFLALLIGTPVLA
ALLWFFEQAGPFGWLWAWGGLTLFTLLLQYVAPAWIMPIFNKFVPLEEGELNNAIMQYARTVGFPLTGIYVIDGSKRSSK
ANAFFTGFGKRKRIALFDTLVSNHSVSELVAVLAHEIGHYKKKHVLINMVLSMVNLGVVFYLLSVFMNNPDLFSAFFMQD
ISVYGSLVFFLLLYSPVEFVLSILLQALSRKHEYEADSFAVSTYSDGFALGEALKKLSRSNLSNLTPHALYVFLNYSHPP
VVQRIRRINEHPAPGHLNH

Sequences:

>Translated_419_residues
MMNGFGQVVLFTLVLTFFLKLIADLLNLRASESGLPPEFQGVYEEDAYRKSQDYLRATTRFSLIGAFVDLLFLLVFWFAG
GFNMLDQLLRAQGYNTVLTGVLYIGALLLLQGILGLPFTLYRTFVIEERFGFNKTTPKVFVADLLKTLFLALLIGTPVLA
ALLWFFEQAGPFGWLWAWGGLTLFTLLLQYVAPAWIMPIFNKFVPLEEGELNNAIMQYARTVGFPLTGIYVIDGSKRSSK
ANAFFTGFGKRKRIALFDTLVSNHSVSELVAVLAHEIGHYKKKHVLINMVLSMVNLGVVFYLLSVFMNNPDLFSAFFMQD
ISVYGSLVFFLLLYSPVEFVLSILLQALSRKHEYEADSFAVSTYSDGFALGEALKKLSRSNLSNLTPHALYVFLNYSHPP
VVQRIRRINEHPAPGHLNH
>Mature_419_residues
MMNGFGQVVLFTLVLTFFLKLIADLLNLRASESGLPPEFQGVYEEDAYRKSQDYLRATTRFSLIGAFVDLLFLLVFWFAG
GFNMLDQLLRAQGYNTVLTGVLYIGALLLLQGILGLPFTLYRTFVIEERFGFNKTTPKVFVADLLKTLFLALLIGTPVLA
ALLWFFEQAGPFGWLWAWGGLTLFTLLLQYVAPAWIMPIFNKFVPLEEGELNNAIMQYARTVGFPLTGIYVIDGSKRSSK
ANAFFTGFGKRKRIALFDTLVSNHSVSELVAVLAHEIGHYKKKHVLINMVLSMVNLGVVFYLLSVFMNNPDLFSAFFMQD
ISVYGSLVFFLLLYSPVEFVLSILLQALSRKHEYEADSFAVSTYSDGFALGEALKKLSRSNLSNLTPHALYVFLNYSHPP
VVQRIRRINEHPAPGHLNH

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=453, Percent_Identity=32.0088300220751, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17505484, Length=401, Percent_Identity=31.4214463840399, Blast_Score=183, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6322577, Length=412, Percent_Identity=35.6796116504854, Blast_Score=225, Evalue=1e-59,
Organism=Drosophila melanogaster, GI19922414, Length=433, Percent_Identity=32.5635103926097, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24654305, Length=293, Percent_Identity=28.6689419795222, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI78707252, Length=398, Percent_Identity=23.3668341708543, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI78707254, Length=398, Percent_Identity=23.3668341708543, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 47240; Mature: 47240

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNGFGQVVLFTLVLTFFLKLIADLLNLRASESGLPPEFQGVYEEDAYRKSQDYLRATTR
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHH
FSLIGAFVDLLFLLVFWFAGGFNMLDQLLRAQGYNTVLTGVLYIGALLLLQGILGLPFTL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
YRTFVIEERFGFNKTTPKVFVADLLKTLFLALLIGTPVLAALLWFFEQAGPFGWLWAWGG
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LTLFTLLLQYVAPAWIMPIFNKFVPLEEGELNNAIMQYARTVGFPLTGIYVIDGSKRSSK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCC
ANAFFTGFGKRKRIALFDTLVSNHSVSELVAVLAHEIGHYKKKHVLINMVLSMVNLGVVF
CCHHEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLLSVFMNNPDLFSAFFMQDISVYGSLVFFLLLYSPVEFVLSILLQALSRKHEYEADSFA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VSTYSDGFALGEALKKLSRSNLSNLTPHALYVFLNYSHPPVVQRIRRINEHPAPGHLNH
EECCCCHHHHHHHHHHHHHCCCCCCCHHHEEEEEECCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MMNGFGQVVLFTLVLTFFLKLIADLLNLRASESGLPPEFQGVYEEDAYRKSQDYLRATTR
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHH
FSLIGAFVDLLFLLVFWFAGGFNMLDQLLRAQGYNTVLTGVLYIGALLLLQGILGLPFTL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
YRTFVIEERFGFNKTTPKVFVADLLKTLFLALLIGTPVLAALLWFFEQAGPFGWLWAWGG
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LTLFTLLLQYVAPAWIMPIFNKFVPLEEGELNNAIMQYARTVGFPLTGIYVIDGSKRSSK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCC
ANAFFTGFGKRKRIALFDTLVSNHSVSELVAVLAHEIGHYKKKHVLINMVLSMVNLGVVF
CCHHEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLLSVFMNNPDLFSAFFMQDISVYGSLVFFLLLYSPVEFVLSILLQALSRKHEYEADSFA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VSTYSDGFALGEALKKLSRSNLSNLTPHALYVFLNYSHPPVVQRIRRINEHPAPGHLNH
EECCCCHHHHHHHHHHHHHCCCCCCCHHHEEEEEECCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]