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The map label for this gene is hsdM [C]

Identifier: 119357510

GI number: 119357510

Start: 1940022

End: 1942010

Strand: Reverse

Name: hsdM [C]

Synonym: Cpha266_1712

Alternate gene names: 119357510

Gene position: 1942010-1940022 (Counterclockwise)

Preceding gene: 119357511

Following gene: 119357509

Centisome position: 61.97

GC content: 58.57

Gene sequence:

>1989_bases
ATGCACTGGATCGCACCTTCCGAAAAAGATACCGCTACCGCCGCACTCGAAAAGCGCCTGTGGGATGCCGCCGACCAGCT
TCGGGCGAACTCCGGCCTCAAGGCCCAGGAGTATTCCGCACCCGTTCTCGGGCTTATTTTCCTGCTTTTTGCCGACGTGC
GGTTCGCCGCCCGGAGGGCTGAGCTTGAATCGGCAAAGAGCAGTACTCGCCGGGGGAGCCGGGTGGACGATCCGGCGGCC
TATCATGCCGAAGGCGTGCTCTACCTTTCGCCAGAAGCGCGGTTTGTCTACCTGCTCAACCGTCCTGAAGCCGAGAACAT
CGGCGTGATGGTCAACGAAGCCATGCGCGCTATCGAGAAGCACAATCCGCAGCTTGCCGGTGTGCTGCCGAAGACCTACT
ACCTGTTCGACAGCCCGCTTCTGAAGCAGTTGCTGAAAAAGGTGTCGGAGATTCCCTCTTCGATGGATTACGATGCGTTC
GGACGCATCTACGAGTACTTTCTCGGCGAATTCGCCATGAGCGAAGGGCAGGGCGGGGGAGAGTTCTATACGCCCGTCAG
CATCGTTCGTCTCCTGACCGAAGTGATCGAGCCATATCACGGGCGCATTCTCGACCCCGCATGCGGTTCCGGCGGCATGT
TCGTCTCCTCGGCCCGGTTCGTTGCCCAGCACAAGCAGAACCCTTCGGCAGAACTCTCCATTCACGGCATCGAGAAGACC
GACGAGACGGGAAGGCTTTGTCGCCTGAACCTTGCGGTGCACGGGCTTGAAGGCCGTATCATGCATGGCGGCAACGTGAA
CAGCTACTACGACGATCCGCATGATGCAACGGGGAATTTTGATTTCGTGCTGGCCAATCCGCCGTTCAATGTTAACGCCG
TTGACAAGGAACGCCTGAAAGATTCGGTCGGTCCGGGACGACGCTTTCCTTTCGGTCTTCCGCGAACCGACAACGCGAAC
TATCTCTGGATACAGCTTTTCTACTCGGCACTGAACGAAAGGGGGAGAGCCGGTTTCGTCATGGCGAACTCGGCTTCCGA
CGCCCGCTCCTCGGAGCAGGAAATCCGTCGCCAGCTTATCGAAAGCCGTACGGTGGACGTAATGGTCGCAGTCGGGCCGA
ACATGTTCTACACCGTCACGCTGCCCTGCACGCTGTGGTTTTTCGACAAGGCGAAAGCAAGGCTTTCGCCACCCTCATCC
CCGGCCCTTCTCCCAAAGGTAGAAGGGGGAGAAGAAGATTTACCATTATCCAGACGCATTCTCACAGAGCGCGACGGGGA
AGGGAATGTACCGAACAGGGCGGATACGGTGCTGTTTATCGATGCACGGCACATCTACCGGCAGGTTGACAGGGCTCATC
GCGACTGGACGCCCGCCCAGATCGGCTTTATGGCCAACCTTGTCCGTCTCTGGCGCGGCGAAGCGCTCGACTACACGCTG
GGTGGCGACGAAGCTCGCGAAAAGATCGAAGAGGTTTTCGCTGCCAAAAGTTCTGACCCGGCAGGCTTGAACGGGCAGGA
GGGGCATTCTGCCCACGCACTGGCCGCCGAATCCCCCGCTCCATACGGATCAAGTGATGAAATTGAAAAACTCCCTTCTA
CCTTTGGGAGAAGGGCCGGGGATGAGGGTGCTGTCAAGCATGAGGGTGCCGGGAACGTCGCCTATCGCGATGAAGCAAAA
GAACACCCTTCGCCCTCTGGGAGAAGGGCCGGGGATGAGGGTGCTGTCAAGCATGAGGGTGCCGGGAACGTCGCCTATAG
CGACATTCCCGGCTTATGCAAGGCCGCCACATTAAAGGAAATAGAGGCGCAGGGCTGGTCGCTCAATCCCGGCAGATATG
TCGGCGTTGCTCCCGGCGAGGCAATCAGCGACGAGGATTTCAAGGTCCAGCTCGAAACGCTGAACGAAGAACTGGAACTT
CTGAATGCGCAGGCGCGTGAACTGGAGGCAACGATTGCCGGAAATGTGGCGCAAATTTTGGAGACCTGA

Upstream 100 bases:

>100_bases
GCCGCAGGATAATCGGACAGGTTTCATTGGAATACAATGCCTGTTAGCTGTATATTACTCTTTATTTTATCCATTTAGCG
CCGATAGTCAAGCAGTAACC

Downstream 100 bases:

>100_bases
CCATGAGTGAATTGTGTGAGGCAACGTGTAAGGAATTCTTACAAGTTCAGTTTGAAGGTACCAGGCAACTGTTCAGAAAT
ACTTAACAGTTCGAGAAAAG

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.MjaXP [H]

Number of amino acids: Translated: 662; Mature: 662

Protein sequence:

>662_residues
MHWIAPSEKDTATAALEKRLWDAADQLRANSGLKAQEYSAPVLGLIFLLFADVRFAARRAELESAKSSTRRGSRVDDPAA
YHAEGVLYLSPEARFVYLLNRPEAENIGVMVNEAMRAIEKHNPQLAGVLPKTYYLFDSPLLKQLLKKVSEIPSSMDYDAF
GRIYEYFLGEFAMSEGQGGGEFYTPVSIVRLLTEVIEPYHGRILDPACGSGGMFVSSARFVAQHKQNPSAELSIHGIEKT
DETGRLCRLNLAVHGLEGRIMHGGNVNSYYDDPHDATGNFDFVLANPPFNVNAVDKERLKDSVGPGRRFPFGLPRTDNAN
YLWIQLFYSALNERGRAGFVMANSASDARSSEQEIRRQLIESRTVDVMVAVGPNMFYTVTLPCTLWFFDKAKARLSPPSS
PALLPKVEGGEEDLPLSRRILTERDGEGNVPNRADTVLFIDARHIYRQVDRAHRDWTPAQIGFMANLVRLWRGEALDYTL
GGDEAREKIEEVFAAKSSDPAGLNGQEGHSAHALAAESPAPYGSSDEIEKLPSTFGRRAGDEGAVKHEGAGNVAYRDEAK
EHPSPSGRRAGDEGAVKHEGAGNVAYSDIPGLCKAATLKEIEAQGWSLNPGRYVGVAPGEAISDEDFKVQLETLNEELEL
LNAQARELEATIAGNVAQILET

Sequences:

>Translated_662_residues
MHWIAPSEKDTATAALEKRLWDAADQLRANSGLKAQEYSAPVLGLIFLLFADVRFAARRAELESAKSSTRRGSRVDDPAA
YHAEGVLYLSPEARFVYLLNRPEAENIGVMVNEAMRAIEKHNPQLAGVLPKTYYLFDSPLLKQLLKKVSEIPSSMDYDAF
GRIYEYFLGEFAMSEGQGGGEFYTPVSIVRLLTEVIEPYHGRILDPACGSGGMFVSSARFVAQHKQNPSAELSIHGIEKT
DETGRLCRLNLAVHGLEGRIMHGGNVNSYYDDPHDATGNFDFVLANPPFNVNAVDKERLKDSVGPGRRFPFGLPRTDNAN
YLWIQLFYSALNERGRAGFVMANSASDARSSEQEIRRQLIESRTVDVMVAVGPNMFYTVTLPCTLWFFDKAKARLSPPSS
PALLPKVEGGEEDLPLSRRILTERDGEGNVPNRADTVLFIDARHIYRQVDRAHRDWTPAQIGFMANLVRLWRGEALDYTL
GGDEAREKIEEVFAAKSSDPAGLNGQEGHSAHALAAESPAPYGSSDEIEKLPSTFGRRAGDEGAVKHEGAGNVAYRDEAK
EHPSPSGRRAGDEGAVKHEGAGNVAYSDIPGLCKAATLKEIEAQGWSLNPGRYVGVAPGEAISDEDFKVQLETLNEELEL
LNAQARELEATIAGNVAQILET
>Mature_662_residues
MHWIAPSEKDTATAALEKRLWDAADQLRANSGLKAQEYSAPVLGLIFLLFADVRFAARRAELESAKSSTRRGSRVDDPAA
YHAEGVLYLSPEARFVYLLNRPEAENIGVMVNEAMRAIEKHNPQLAGVLPKTYYLFDSPLLKQLLKKVSEIPSSMDYDAF
GRIYEYFLGEFAMSEGQGGGEFYTPVSIVRLLTEVIEPYHGRILDPACGSGGMFVSSARFVAQHKQNPSAELSIHGIEKT
DETGRLCRLNLAVHGLEGRIMHGGNVNSYYDDPHDATGNFDFVLANPPFNVNAVDKERLKDSVGPGRRFPFGLPRTDNAN
YLWIQLFYSALNERGRAGFVMANSASDARSSEQEIRRQLIESRTVDVMVAVGPNMFYTVTLPCTLWFFDKAKARLSPPSS
PALLPKVEGGEEDLPLSRRILTERDGEGNVPNRADTVLFIDARHIYRQVDRAHRDWTPAQIGFMANLVRLWRGEALDYTL
GGDEAREKIEEVFAAKSSDPAGLNGQEGHSAHALAAESPAPYGSSDEIEKLPSTFGRRAGDEGAVKHEGAGNVAYRDEAK
EHPSPSGRRAGDEGAVKHEGAGNVAYSDIPGLCKAATLKEIEAQGWSLNPGRYVGVAPGEAISDEDFKVQLETLNEELEL
LNAQARELEATIAGNVAQILET

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=272, Percent_Identity=23.8970588235294, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 72694; Mature: 72694

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHWIAPSEKDTATAALEKRLWDAADQLRANSGLKAQEYSAPVLGLIFLLFADVRFAARRA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHH
ELESAKSSTRRGSRVDDPAAYHAEGVLYLSPEARFVYLLNRPEAENIGVMVNEAMRAIEK
HHHHHHHHHCCCCCCCCCCHHCCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
HNPQLAGVLPKTYYLFDSPLLKQLLKKVSEIPSSMDYDAFGRIYEYFLGEFAMSEGQGGG
CCCCEEECCCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
EFYTPVSIVRLLTEVIEPYHGRILDPACGSGGMFVSSARFVAQHKQNPSAELSIHGIEKT
CEECHHHHHHHHHHHHCCCCCEEECCCCCCCCEEHHHHHHHHHHCCCCCCEEEEECCCCC
DETGRLCRLNLAVHGLEGRIMHGGNVNSYYDDPHDATGNFDFVLANPPFNVNAVDKERLK
CCCCCEEEEEEEEECCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHH
DSVGPGRRFPFGLPRTDNANYLWIQLFYSALNERGRAGFVMANSASDARSSEQEIRRQLI
HHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHH
ESRTVDVMVAVGPNMFYTVTLPCTLWFFDKAKARLSPPSSPALLPKVEGGEEDLPLSRRI
HCCCEEEEEEECCCEEEEEEECEEEEEECCCHHCCCCCCCCCCCCCCCCCCCCCCHHHHH
LTERDGEGNVPNRADTVLFIDARHIYRQVDRAHRDWTPAQIGFMANLVRLWRGEALDYTL
HHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEC
GGDEAREKIEEVFAAKSSDPAGLNGQEGHSAHALAAESPAPYGSSDEIEKLPSTFGRRAG
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCC
DEGAVKHEGAGNVAYRDEAKEHPSPSGRRAGDEGAVKHEGAGNVAYSDIPGLCKAATLKE
CCCCEECCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEECCCCCCEECCCCCHHHHHHHHH
IEAQGWSLNPGRYVGVAPGEAISDEDFKVQLETLNEELELLNAQARELEATIAGNVAQIL
HHCCCCCCCCCCEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ET
CC
>Mature Secondary Structure
MHWIAPSEKDTATAALEKRLWDAADQLRANSGLKAQEYSAPVLGLIFLLFADVRFAARRA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHH
ELESAKSSTRRGSRVDDPAAYHAEGVLYLSPEARFVYLLNRPEAENIGVMVNEAMRAIEK
HHHHHHHHHCCCCCCCCCCHHCCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
HNPQLAGVLPKTYYLFDSPLLKQLLKKVSEIPSSMDYDAFGRIYEYFLGEFAMSEGQGGG
CCCCEEECCCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
EFYTPVSIVRLLTEVIEPYHGRILDPACGSGGMFVSSARFVAQHKQNPSAELSIHGIEKT
CEECHHHHHHHHHHHHCCCCCEEECCCCCCCCEEHHHHHHHHHHCCCCCCEEEEECCCCC
DETGRLCRLNLAVHGLEGRIMHGGNVNSYYDDPHDATGNFDFVLANPPFNVNAVDKERLK
CCCCCEEEEEEEEECCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHH
DSVGPGRRFPFGLPRTDNANYLWIQLFYSALNERGRAGFVMANSASDARSSEQEIRRQLI
HHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHH
ESRTVDVMVAVGPNMFYTVTLPCTLWFFDKAKARLSPPSSPALLPKVEGGEEDLPLSRRI
HCCCEEEEEEECCCEEEEEEECEEEEEECCCHHCCCCCCCCCCCCCCCCCCCCCCHHHHH
LTERDGEGNVPNRADTVLFIDARHIYRQVDRAHRDWTPAQIGFMANLVRLWRGEALDYTL
HHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEC
GGDEAREKIEEVFAAKSSDPAGLNGQEGHSAHALAAESPAPYGSSDEIEKLPSTFGRRAG
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCC
DEGAVKHEGAGNVAYRDEAKEHPSPSGRRAGDEGAVKHEGAGNVAYSDIPGLCKAATLKE
CCCCEECCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEECCCCCCEECCCCCHHHHHHHHH
IEAQGWSLNPGRYVGVAPGEAISDEDFKVQLETLNEELELLNAQARELEATIAGNVAQIL
HHCCCCCCCCCCEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ET
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]