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The map label for this gene is hsdM [C]

Identifier: 119357295

GI number: 119357295

Start: 1691163

End: 1692650

Strand: Reverse

Name: hsdM [C]

Synonym: Cpha266_1491

Alternate gene names: 119357295

Gene position: 1692650-1691163 (Counterclockwise)

Preceding gene: 119357296

Following gene: 119357294

Centisome position: 54.01

GC content: 53.56

Gene sequence:

>1488_bases
ATGACCAACACCCCATCATCCATAGTTTCGAAAGTCTGGTCGTTCTGCCACGTGCTGCGCGACAGCGGCGTGAGCTATGG
CGACTATCTCGAACAGTTGACCTTTCTCATCTTTCTGAAAATGGCCGATGAGTACACCAGGCCGCCATATAACCGCACAA
TCGACATTCCGTCCGAGTACACCTGGCCGAAACTCAAGGCAAAGCGCGGTGCCGAGCTTGAAGTGCTCTACGCCAGACTG
CTTCGCGATCTTGGCCAGAAGCCGGGCATGCTCGGGCAGATATTCCTGAAAGCGCAGAACAAGATTGCCGATCCTGCCAT
GCTCTACAAGGTTATCGACATGATCGATAAGGAGAGCTGGGTGATGATGGGGGCCGATGTCAAAGGGGAGATTTATGAAG
GGCTGCTTGAAAAGAACGCCGAAGATACCAAAAGCGGAGCAGGGCAGTACTTTACGCCCCGCGCGCTGATCGAGATCATG
GTGAAGTGTGTCCGGCCTGAACCACGGAAAACCATCGGCGATCCTGCATGCGGAACGGGCGGTTTTTTTCTGAAGGCTTA
CGATTTCATCACAACCCGCTACAAGCTTGATAGGGATGAAAAGGAGTTTCTGAAGCATCGCACGTTCGGCGGTAACGAAA
TTGTGCCCGGAACGAGAAGGCTTTGCCTGATGAACATGTTTCTGCACAACATCGGCGAACTTGACGGGAATGTCGCCGTT
TCATCCACCGATGCGCTTGTTGCCGATAACGGCGTCCGGTACGATTATGTCCTCACGAATCCCCCCTTCGGAAAGAAGAG
CAGCATGACCTTCACCAATGACGAAGAGGAGCAGGAAAAGGAGAGTCTCGTTTATAACCGGCAGGATTTCTGGGCGATAA
CCGCCAACAAGCAGCTTAACTTTCTGCAGCATATCCATACCATCCTGAAAGTTTACGGGCAGGCCGCCGTGGTGCTTCCC
GATAACGTGCTGTTTGAAGGGGGGGCGGGGGAACTGGTGCGGAAGAAACTGCTTGAAACGACCGAATTGCACACCATTCT
CAGGCTGCCGACCGGTATCTTTTATGCTCAGGGAGTGAAAGCGAATGTCTTCTTTTTCGACGTCATGCCTGCCGATAAAG
ATCCCTGGACACGCGAAGTCTGGTTCTACGACTACCGAACCAATGTGCACCACACCCTGAAGAAAAGCCCGCTGAAAGCC
TCGGACCTGCAGGAGTTCGTAGAGTGTTACAACCCCGCAAACCGCCACAAACGCAAGGAGACCTGGTCGCAGGAAAACCC
GGAAGGCCGCTGGCGCAAATACACCTACGATGAAATCGTCGCCCGAGACAAAACCAACCTCGACATCTTCTGGCTGAAAG
ACAAAAGCCTCGCCGACCTCGACAACCTTCCCGACCCTGATCTGCTCGCCGGAGAGATCATCGAAAACCTCGAAGCCGGT
CTGGCAAGCTTTCGGGAGATTCTGGGTGTGCTGAACAATGGAAAGTGA

Upstream 100 bases:

>100_bases
CAACCCGCAACGATCCGGACTGGGAGCCTGCCGAGAAGCTGCTTGAGCGGATCAGGGCTGAAAAAAACCAATCGAAGAAA
CAAGCATTAACGTAGTACCC

Downstream 100 bases:

>100_bases
AATGCAGCTAAACAACGTGAGAAAATAAATCAGGTTCCCTCAATAACATCCCTGTTGTTTTATGGAAAAAATAATTGAAG
CTGTTCTGGCATTGATTCCG

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.BthVORF4518P [H]

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MTNTPSSIVSKVWSFCHVLRDSGVSYGDYLEQLTFLIFLKMADEYTRPPYNRTIDIPSEYTWPKLKAKRGAELEVLYARL
LRDLGQKPGMLGQIFLKAQNKIADPAMLYKVIDMIDKESWVMMGADVKGEIYEGLLEKNAEDTKSGAGQYFTPRALIEIM
VKCVRPEPRKTIGDPACGTGGFFLKAYDFITTRYKLDRDEKEFLKHRTFGGNEIVPGTRRLCLMNMFLHNIGELDGNVAV
SSTDALVADNGVRYDYVLTNPPFGKKSSMTFTNDEEEQEKESLVYNRQDFWAITANKQLNFLQHIHTILKVYGQAAVVLP
DNVLFEGGAGELVRKKLLETTELHTILRLPTGIFYAQGVKANVFFFDVMPADKDPWTREVWFYDYRTNVHHTLKKSPLKA
SDLQEFVECYNPANRHKRKETWSQENPEGRWRKYTYDEIVARDKTNLDIFWLKDKSLADLDNLPDPDLLAGEIIENLEAG
LASFREILGVLNNGK

Sequences:

>Translated_495_residues
MTNTPSSIVSKVWSFCHVLRDSGVSYGDYLEQLTFLIFLKMADEYTRPPYNRTIDIPSEYTWPKLKAKRGAELEVLYARL
LRDLGQKPGMLGQIFLKAQNKIADPAMLYKVIDMIDKESWVMMGADVKGEIYEGLLEKNAEDTKSGAGQYFTPRALIEIM
VKCVRPEPRKTIGDPACGTGGFFLKAYDFITTRYKLDRDEKEFLKHRTFGGNEIVPGTRRLCLMNMFLHNIGELDGNVAV
SSTDALVADNGVRYDYVLTNPPFGKKSSMTFTNDEEEQEKESLVYNRQDFWAITANKQLNFLQHIHTILKVYGQAAVVLP
DNVLFEGGAGELVRKKLLETTELHTILRLPTGIFYAQGVKANVFFFDVMPADKDPWTREVWFYDYRTNVHHTLKKSPLKA
SDLQEFVECYNPANRHKRKETWSQENPEGRWRKYTYDEIVARDKTNLDIFWLKDKSLADLDNLPDPDLLAGEIIENLEAG
LASFREILGVLNNGK
>Mature_494_residues
TNTPSSIVSKVWSFCHVLRDSGVSYGDYLEQLTFLIFLKMADEYTRPPYNRTIDIPSEYTWPKLKAKRGAELEVLYARLL
RDLGQKPGMLGQIFLKAQNKIADPAMLYKVIDMIDKESWVMMGADVKGEIYEGLLEKNAEDTKSGAGQYFTPRALIEIMV
KCVRPEPRKTIGDPACGTGGFFLKAYDFITTRYKLDRDEKEFLKHRTFGGNEIVPGTRRLCLMNMFLHNIGELDGNVAVS
STDALVADNGVRYDYVLTNPPFGKKSSMTFTNDEEEQEKESLVYNRQDFWAITANKQLNFLQHIHTILKVYGQAAVVLPD
NVLFEGGAGELVRKKLLETTELHTILRLPTGIFYAQGVKANVFFFDVMPADKDPWTREVWFYDYRTNVHHTLKKSPLKAS
DLQEFVECYNPANRHKRKETWSQENPEGRWRKYTYDEIVARDKTNLDIFWLKDKSLADLDNLPDPDLLAGEIIENLEAGL
ASFREILGVLNNGK

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=521, Percent_Identity=39.5393474088292, Blast_Score=338, Evalue=7e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 56683; Mature: 56552

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTPSSIVSKVWSFCHVLRDSGVSYGDYLEQLTFLIFLKMADEYTRPPYNRTIDIPSEY
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCC
TWPKLKAKRGAELEVLYARLLRDLGQKPGMLGQIFLKAQNKIADPAMLYKVIDMIDKESW
CCCHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCE
VMMGADVKGEIYEGLLEKNAEDTKSGAGQYFTPRALIEIMVKCVRPEPRKTIGDPACGTG
EEECCCCCHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCHHCCCCCCCCCC
GFFLKAYDFITTRYKLDRDEKEFLKHRTFGGNEIVPGTRRLCLMNMFLHNIGELDGNVAV
CHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEE
SSTDALVADNGVRYDYVLTNPPFGKKSSMTFTNDEEEQEKESLVYNRQDFWAITANKQLN
ECCCCEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCHHH
FLQHIHTILKVYGQAAVVLPDNVLFEGGAGELVRKKLLETTELHTILRLPTGIFYAQGVK
HHHHHHHHHHHHCCEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCE
ANVFFFDVMPADKDPWTREVWFYDYRTNVHHTLKKSPLKASDLQEFVECYNPANRHKRKE
EEEEEEEEECCCCCCCCEEEEEEEECCCHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHH
TWSQENPEGRWRKYTYDEIVARDKTNLDIFWLKDKSLADLDNLPDPDLLAGEIIENLEAG
HCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHH
LASFREILGVLNNGK
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
TNTPSSIVSKVWSFCHVLRDSGVSYGDYLEQLTFLIFLKMADEYTRPPYNRTIDIPSEY
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCC
TWPKLKAKRGAELEVLYARLLRDLGQKPGMLGQIFLKAQNKIADPAMLYKVIDMIDKESW
CCCHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCE
VMMGADVKGEIYEGLLEKNAEDTKSGAGQYFTPRALIEIMVKCVRPEPRKTIGDPACGTG
EEECCCCCHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCHHCCCCCCCCCC
GFFLKAYDFITTRYKLDRDEKEFLKHRTFGGNEIVPGTRRLCLMNMFLHNIGELDGNVAV
CHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEE
SSTDALVADNGVRYDYVLTNPPFGKKSSMTFTNDEEEQEKESLVYNRQDFWAITANKQLN
ECCCCEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCHHH
FLQHIHTILKVYGQAAVVLPDNVLFEGGAGELVRKKLLETTELHTILRLPTGIFYAQGVK
HHHHHHHHHHHHCCEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCE
ANVFFFDVMPADKDPWTREVWFYDYRTNVHHTLKKSPLKASDLQEFVECYNPANRHKRKE
EEEEEEEEECCCCCCCCEEEEEEEECCCHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHH
TWSQENPEGRWRKYTYDEIVARDKTNLDIFWLKDKSLADLDNLPDPDLLAGEIIENLEAG
HCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHH
LASFREILGVLNNGK
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]