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The map label for this gene is yrhP [H]

Identifier: 119357229

GI number: 119357229

Start: 1614836

End: 1615459

Strand: Reverse

Name: yrhP [H]

Synonym: Cpha266_1421

Alternate gene names: 119357229

Gene position: 1615459-1614836 (Counterclockwise)

Preceding gene: 119357230

Following gene: 119357228

Centisome position: 51.55

GC content: 50.0

Gene sequence:

>624_bases
ATGATTGATCAGCATGTTCTGTTTATGTTTTTTGTTTCCTCGGTCGTTCTTTCACTTTCGCCGGGGCCGGATAATCTCTT
TGTTATGGCTCAGTCGGCCCGGAACGGTCGGCTTGCCGGGATGATGGTTACGCTTGGCTTGTGTACCGGACTTGTTTTGC
ATACACTTGCCGTTGCGTTCGGGCTTGCGGCTCTTGTGGCCGCATCGGCTGTTGCTTTTACCGTGCTTAAATTCGCAGGA
GCAGCTTACCTTCTTTTTCTTGCATGGAAGGCGTTTCATGCCGATGTCGAAAAGGATTCTTCTGACGTTTCGCAGGTTGA
GCGGGGGAAACTCTACAGGCGGGGGATTGTTATGAATATTTCCAACCCGAAGGTGTCGCTTTTTTTTCTTGCTTTTCTGC
CGCAGTTTGCCGATCCGAAAAATGGGCCTCTGGTGCCGCAACTTCTGTTTCTCGGCGCGATTTTTATTGTGGCTGCACTG
CTTGTTTTTTCGCTGCTCTTTTTTGTTGCTGGCGGAGCAGGGGCTCGCTTTCGTCGTTCCGCGAAAGCCCGCAGGGTAGT
GAACAGGATTGCCGGAACGATTTTTGCTGGTTTTGCCTTAAAACTTCTTTTTACTGAACGATAG

Upstream 100 bases:

>100_bases
TGCAAATCGCTCTCTTTATTGTTGATCGCCTGTTTTTAAAGTTGTCTGTTGTTAATAAAATGCTTGAGGAGAGGAAAGAT
GTTTAACCTTTCTTTTTACC

Downstream 100 bases:

>100_bases
TGATCGGAATGTGATTGATAAGCGGGCAGCGTTGTTGTGTCTCTCCTTGATGAGTTTTCATGCGTAAAGGTTTCTGCTGT
GGTTTGTCTGTAATGTGTTC

Product: lysine exporter protein LysE/YggA

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MIDQHVLFMFFVSSVVLSLSPGPDNLFVMAQSARNGRLAGMMVTLGLCTGLVLHTLAVAFGLAALVAASAVAFTVLKFAG
AAYLLFLAWKAFHADVEKDSSDVSQVERGKLYRRGIVMNISNPKVSLFFLAFLPQFADPKNGPLVPQLLFLGAIFIVAAL
LVFSLLFFVAGGAGARFRRSAKARRVVNRIAGTIFAGFALKLLFTER

Sequences:

>Translated_207_residues
MIDQHVLFMFFVSSVVLSLSPGPDNLFVMAQSARNGRLAGMMVTLGLCTGLVLHTLAVAFGLAALVAASAVAFTVLKFAG
AAYLLFLAWKAFHADVEKDSSDVSQVERGKLYRRGIVMNISNPKVSLFFLAFLPQFADPKNGPLVPQLLFLGAIFIVAAL
LVFSLLFFVAGGAGARFRRSAKARRVVNRIAGTIFAGFALKLLFTER
>Mature_207_residues
MIDQHVLFMFFVSSVVLSLSPGPDNLFVMAQSARNGRLAGMMVTLGLCTGLVLHTLAVAFGLAALVAASAVAFTVLKFAG
AAYLLFLAWKAFHADVEKDSSDVSQVERGKLYRRGIVMNISNPKVSLFFLAFLPQFADPKNGPLVPQLLFLGAIFIVAAL
LVFSLLFFVAGGAGARFRRSAKARRVVNRIAGTIFAGFALKLLFTER

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=189, Percent_Identity=33.8624338624339, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788099, Length=207, Percent_Identity=31.4009661835749, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1786522, Length=194, Percent_Identity=28.8659793814433, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI48994978, Length=199, Percent_Identity=26.1306532663317, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22318; Mature: 22318

Theoretical pI: Translated: 11.37; Mature: 11.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDQHVLFMFFVSSVVLSLSPGPDNLFVMAQSARNGRLAGMMVTLGLCTGLVLHTLAVAF
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLAALVAASAVAFTVLKFAGAAYLLFLAWKAFHADVEKDSSDVSQVERGKLYRRGIVMNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEE
SNPKVSLFFLAFLPQFADPKNGPLVPQLLFLGAIFIVAALLVFSLLFFVAGGAGARFRRS
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AKARRVVNRIAGTIFAGFALKLLFTER
HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDQHVLFMFFVSSVVLSLSPGPDNLFVMAQSARNGRLAGMMVTLGLCTGLVLHTLAVAF
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLAALVAASAVAFTVLKFAGAAYLLFLAWKAFHADVEKDSSDVSQVERGKLYRRGIVMNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEE
SNPKVSLFFLAFLPQFADPKNGPLVPQLLFLGAIFIVAALLVFSLLFFVAGGAGARFRRS
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AKARRVVNRIAGTIFAGFALKLLFTER
HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]