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The map label for this gene is fabF [H]

Identifier: 119356924

GI number: 119356924

Start: 1248131

End: 1249366

Strand: Reverse

Name: fabF [H]

Synonym: Cpha266_1103

Alternate gene names: 119356924

Gene position: 1249366-1248131 (Counterclockwise)

Preceding gene: 119356925

Following gene: 119356923

Centisome position: 39.87

GC content: 48.46

Gene sequence:

>1236_bases
ATGCTTGATATCGTTGTAACCGACTTTGGTATTACCTCTCCGATCGGGATATCGGTACCTGAGTTTGAAAAGCGGATGTT
TGCAGGTGATTCGGGCATTATCGACCTGCGAGGATCACTTGTTGGAAATAACTTTCCTGTTGCATTCGGAGGGGTTGTTG
ATGACACGAACATCCCGCCGGCAACGGAACTGGGCCTGCCTCTCGGCCTGCATACAAATGGAGGCCGGTATCTTATCCAT
GCCCTTCAGCAGATTCTTCAGCGACTGCCTGAGTCAGTTCCGATTGACGCTCTTGTTCAGGCATCTCCGGCAGGTATATA
TTTTGATATTGTAAGGGATTCGTTGATGCATTACGATCCCGATTCATTTATCTGGGATGAACTTCGTGCCGAATGGGTTG
TTGAAATTATTGCCGAAAAACTCAAACAACGGGGACACGGCTCAATTGATCCCGAGAACATAATCAGTGTCAATTCCGCA
TGTGCCGCAGGAAGTCAGGCAATTGGGGTTGCATACCACCTGCTGAAATCGGGGCGTATAAAAAGATGCCTTGTTTGTGC
TGTAGATGCCGGAGCATGGGAAAGCCAGCTCATGAATTTTCATCTGCTGCATACACTCACAACCGATGACGTTCCGGCTC
ATACTGCCAGCAGACCGTTTTCGAAAAGCCGTTCCGGTTTTGTCAAAAGTGAGGCCGCGGCTGTCCTTCTTCTTGAAACA
AGAGCTGCCGCTGAAGAACGAAAAGCTGAAATACTTGCTCAGGTATGTGGCTACGCTTTTAATTCGGACGCCTACCGATT
GACGGATGGCAGAGATGATAATCAATGTGTTGTCAGGGCTATGGAAGATGCCATAGCCGATGCAGGCATTGAAAAAACAG
AGATCGGTTATATCAATGCGCACGGCACCTCAACAGTGCTGAATGACCGCCTTGAAACCCAGGCTATAAAAAAGGTATTC
GGTGAGAATGCCTATCAAATTCCCGTCAGCTCGCTCAAATCGCAAATCGGGCACTCGACTGTCGCTGCCGGAGCTGTGGA
GGCTATTGCCTGTATTCTGATGCTGCTTCGCCAGAAAATAACGCCCACGATCAATCTGCACGATCCTGATCCTGACTGTG
ATCTCGATTATGTTCCCGAAGGAAGTCGTGATGTTGCGATTGATTACATTCTCAGCAACAGTTTTGGATTTGGCGGTCAG
AACGCATGCCTTGTACTAAAAAAGGAGCGGAACTGA

Upstream 100 bases:

>100_bases
AAGGGTGACGACATCACTGATATTTCCGTTCAGGATATTATCGATTATATGATGCTGGTTCTTCGCAAGAAAGAAGAAGA
AGAAAAACAATAGTACGCTC

Downstream 100 bases:

>100_bases
TGGAAAAACGTCTTGCACTTATAACAGGCGGAACTTCAGGTATAGGCTTCGGTGCAGCCAAAGCGCTTGCCGAAAAGTAC
GACCTTGCTCTTGCATATGC

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MLDIVVTDFGITSPIGISVPEFEKRMFAGDSGIIDLRGSLVGNNFPVAFGGVVDDTNIPPATELGLPLGLHTNGGRYLIH
ALQQILQRLPESVPIDALVQASPAGIYFDIVRDSLMHYDPDSFIWDELRAEWVVEIIAEKLKQRGHGSIDPENIISVNSA
CAAGSQAIGVAYHLLKSGRIKRCLVCAVDAGAWESQLMNFHLLHTLTTDDVPAHTASRPFSKSRSGFVKSEAAAVLLLET
RAAAEERKAEILAQVCGYAFNSDAYRLTDGRDDNQCVVRAMEDAIADAGIEKTEIGYINAHGTSTVLNDRLETQAIKKVF
GENAYQIPVSSLKSQIGHSTVAAGAVEAIACILMLLRQKITPTINLHDPDPDCDLDYVPEGSRDVAIDYILSNSFGFGGQ
NACLVLKKERN

Sequences:

>Translated_411_residues
MLDIVVTDFGITSPIGISVPEFEKRMFAGDSGIIDLRGSLVGNNFPVAFGGVVDDTNIPPATELGLPLGLHTNGGRYLIH
ALQQILQRLPESVPIDALVQASPAGIYFDIVRDSLMHYDPDSFIWDELRAEWVVEIIAEKLKQRGHGSIDPENIISVNSA
CAAGSQAIGVAYHLLKSGRIKRCLVCAVDAGAWESQLMNFHLLHTLTTDDVPAHTASRPFSKSRSGFVKSEAAAVLLLET
RAAAEERKAEILAQVCGYAFNSDAYRLTDGRDDNQCVVRAMEDAIADAGIEKTEIGYINAHGTSTVLNDRLETQAIKKVF
GENAYQIPVSSLKSQIGHSTVAAGAVEAIACILMLLRQKITPTINLHDPDPDCDLDYVPEGSRDVAIDYILSNSFGFGGQ
NACLVLKKERN
>Mature_411_residues
MLDIVVTDFGITSPIGISVPEFEKRMFAGDSGIIDLRGSLVGNNFPVAFGGVVDDTNIPPATELGLPLGLHTNGGRYLIH
ALQQILQRLPESVPIDALVQASPAGIYFDIVRDSLMHYDPDSFIWDELRAEWVVEIIAEKLKQRGHGSIDPENIISVNSA
CAAGSQAIGVAYHLLKSGRIKRCLVCAVDAGAWESQLMNFHLLHTLTTDDVPAHTASRPFSKSRSGFVKSEAAAVLLLET
RAAAEERKAEILAQVCGYAFNSDAYRLTDGRDDNQCVVRAMEDAIADAGIEKTEIGYINAHGTSTVLNDRLETQAIKKVF
GENAYQIPVSSLKSQIGHSTVAAGAVEAIACILMLLRQKITPTINLHDPDPDCDLDYVPEGSRDVAIDYILSNSFGFGGQ
NACLVLKKERN

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=254, Percent_Identity=40.1574803149606, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI223972627, Length=149, Percent_Identity=44.2953020134228, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI41872631, Length=266, Percent_Identity=25.9398496240602, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787337, Length=255, Percent_Identity=42.7450980392157, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI1788663, Length=261, Percent_Identity=34.8659003831418, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71983541, Length=277, Percent_Identity=36.8231046931408, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71983535, Length=258, Percent_Identity=37.5968992248062, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17550940, Length=260, Percent_Identity=30, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI212642053, Length=264, Percent_Identity=26.1363636363636, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6320904, Length=266, Percent_Identity=34.9624060150376, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24644341, Length=426, Percent_Identity=33.5680751173709, Blast_Score=177, Evalue=8e-45,
Organism=Drosophila melanogaster, GI221330659, Length=262, Percent_Identity=28.6259541984733, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19920632, Length=262, Percent_Identity=28.6259541984733, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24581345, Length=262, Percent_Identity=28.2442748091603, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 44488; Mature: 44488

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDIVVTDFGITSPIGISVPEFEKRMFAGDSGIIDLRGSLVGNNFPVAFGGVVDDTNIPP
CEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCEEECCEECCCCCCC
ATELGLPLGLHTNGGRYLIHALQQILQRLPESVPIDALVQASPAGIYFDIVRDSLMHYDP
CHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHEECCCCCEEHHHHHHHHHHCCC
DSFIWDELRAEWVVEIIAEKLKQRGHGSIDPENIISVNSACAAGSQAIGVAYHLLKSGRI
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCHHCCCCHHHHHHHHHHHCCCC
KRCLVCAVDAGAWESQLMNFHLLHTLTTDDVPAHTASRPFSKSRSGFVKSEAAAVLLLET
CEEEEEEECCCCHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
RAAAEERKAEILAQVCGYAFNSDAYRLTDGRDDNQCVVRAMEDAIADAGIEKTEIGYINA
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEC
HGTSTVLNDRLETQAIKKVFGENAYQIPVSSLKSQIGHSTVAAGAVEAIACILMLLRQKI
CCCHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
TPTINLHDPDPDCDLDYVPEGSRDVAIDYILSNSFGFGGQNACLVLKKERN
CCEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MLDIVVTDFGITSPIGISVPEFEKRMFAGDSGIIDLRGSLVGNNFPVAFGGVVDDTNIPP
CEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCEEECCEECCCCCCC
ATELGLPLGLHTNGGRYLIHALQQILQRLPESVPIDALVQASPAGIYFDIVRDSLMHYDP
CHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHEECCCCCEEHHHHHHHHHHCCC
DSFIWDELRAEWVVEIIAEKLKQRGHGSIDPENIISVNSACAAGSQAIGVAYHLLKSGRI
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCHHCCCCHHHHHHHHHHHCCCC
KRCLVCAVDAGAWESQLMNFHLLHTLTTDDVPAHTASRPFSKSRSGFVKSEAAAVLLLET
CEEEEEEECCCCHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
RAAAEERKAEILAQVCGYAFNSDAYRLTDGRDDNQCVVRAMEDAIADAGIEKTEIGYINA
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEC
HGTSTVLNDRLETQAIKKVFGENAYQIPVSSLKSQIGHSTVAAGAVEAIACILMLLRQKI
CCCHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
TPTINLHDPDPDCDLDYVPEGSRDVAIDYILSNSFGFGGQNACLVLKKERN
CCEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]