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The map label for this gene is tktB [C]

Identifier: 119356844

GI number: 119356844

Start: 1156965

End: 1157876

Strand: Reverse

Name: tktB [C]

Synonym: Cpha266_1017

Alternate gene names: 119356844

Gene position: 1157876-1156965 (Counterclockwise)

Preceding gene: 119356845

Following gene: 119356843

Centisome position: 36.95

GC content: 49.34

Gene sequence:

>912_bases
ATGGCAAAAGATATAAAAACCTATCCACATGATAAAAAAGGCGAGCTTCTTGAGCTTGCTTCGATAGATCAGCTTGACAT
GATGGCTATCCAGGTCAGAAGAGATATCGTGCGAATGCTCAGTATGGCAAACTCCGGTCATACCGGCGGATCTCTTGGCA
TGGCTGACATTTTCACCGCGCTCTATTTCAGACTTATCAAGCACGATCCTCATAATTTCTGGAAACAGGACGATCAGGAT
CTGGTGTTTCTTTCCAATGGCCATATTGCTCCGGTATGGTATAGCGTTCTTGCCAGATCAGGCTATTTCCCTCTCCATGA
GCTGAACTCATTGCGTCAGATCAGTTCCTACCTGCAAGGACACCCCACCTCTGAAGCGAAGCTCCCCGGTATAAGAATCG
CATCGGGCTCACTCGGTCAGGGTCTTTCTGCTGCCGCCGGCGCTGCTCTGGGGCTCAGACTTGACAACAAAAACAACGAC
ATATACTGCCTCATGGGAGACGGGGAGTGTCAGGAAGGTCAAATCTGGGAAGCTGCTATGAGTGCCGCACATTACGATCT
CGGAAATCTGATCGGCATTGTTGATTGCAACAGTCTTCAAATCGACGGCGAGGTACAAAGTGTCATGAGCCTTGAGCCTT
TTGGCGATAAATGGCGAGCCTTCGGATGGGAGGTTTACCATTGCGATGGCAACGATATTGAGGATGTTATCGCCTCGATC
AGTCGTATCCGTGACAGGGATGATCGCAAAAGTCCCGCTGTGCTTCTGGCAACAACGATAATGGGTAAAGGGGTACCTTT
CTTTGAAGGCTCCATGCCCGACAAGAGCAACTGGCATGGAAAACCACCATCACAGGATGATGCGGAAAAAGCGCTTGCCA
TTCTTGGCGAAACCGTCTTTGGCGATTTTTAA

Upstream 100 bases:

>100_bases
CTCATGTTGCTCAAGACGATTAACAGGGATGACCGTGTTATCAGCTCTGTAACTTTGTTGTTTTGATTCATTAATCCTTT
AAGAAGTTTATTGAAACACC

Downstream 100 bases:

>100_bases
ACACAAGAGGCTTTGTGCAGATTATTGCAGGAAAATATAAGGGGAATAAAATCCGAAGAACCGACACCCTTGCCGTTCGC
CCATGCAGCAGCCGGGTAAA

Product: transketolase subunit A

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MAKDIKTYPHDKKGELLELASIDQLDMMAIQVRRDIVRMLSMANSGHTGGSLGMADIFTALYFRLIKHDPHNFWKQDDQD
LVFLSNGHIAPVWYSVLARSGYFPLHELNSLRQISSYLQGHPTSEAKLPGIRIASGSLGQGLSAAAGAALGLRLDNKNND
IYCLMGDGECQEGQIWEAAMSAAHYDLGNLIGIVDCNSLQIDGEVQSVMSLEPFGDKWRAFGWEVYHCDGNDIEDVIASI
SRIRDRDDRKSPAVLLATTIMGKGVPFFEGSMPDKSNWHGKPPSQDDAEKALAILGETVFGDF

Sequences:

>Translated_303_residues
MAKDIKTYPHDKKGELLELASIDQLDMMAIQVRRDIVRMLSMANSGHTGGSLGMADIFTALYFRLIKHDPHNFWKQDDQD
LVFLSNGHIAPVWYSVLARSGYFPLHELNSLRQISSYLQGHPTSEAKLPGIRIASGSLGQGLSAAAGAALGLRLDNKNND
IYCLMGDGECQEGQIWEAAMSAAHYDLGNLIGIVDCNSLQIDGEVQSVMSLEPFGDKWRAFGWEVYHCDGNDIEDVIASI
SRIRDRDDRKSPAVLLATTIMGKGVPFFEGSMPDKSNWHGKPPSQDDAEKALAILGETVFGDF
>Mature_302_residues
AKDIKTYPHDKKGELLELASIDQLDMMAIQVRRDIVRMLSMANSGHTGGSLGMADIFTALYFRLIKHDPHNFWKQDDQDL
VFLSNGHIAPVWYSVLARSGYFPLHELNSLRQISSYLQGHPTSEAKLPGIRIASGSLGQGLSAAAGAALGLRLDNKNNDI
YCLMGDGECQEGQIWEAAMSAAHYDLGNLIGIVDCNSLQIDGEVQSVMSLEPFGDKWRAFGWEVYHCDGNDIEDVIASIS
RIRDRDDRKSPAVLLATTIMGKGVPFFEGSMPDKSNWHGKPPSQDDAEKALAILGETVFGDF

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=285, Percent_Identity=33.3333333333333, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI205277463, Length=278, Percent_Identity=33.4532374100719, Blast_Score=154, Evalue=9e-38,
Organism=Homo sapiens, GI4507521, Length=278, Percent_Identity=33.4532374100719, Blast_Score=154, Evalue=9e-38,
Organism=Homo sapiens, GI225637459, Length=282, Percent_Identity=26.5957446808511, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI225637463, Length=173, Percent_Identity=33.5260115606936, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI225637461, Length=173, Percent_Identity=33.5260115606936, Blast_Score=105, Evalue=6e-23,
Organism=Escherichia coli, GI1788808, Length=285, Percent_Identity=35.0877192982456, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI48994911, Length=276, Percent_Identity=35.1449275362319, Blast_Score=126, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17539652, Length=261, Percent_Identity=34.0996168582375, Blast_Score=154, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6325331, Length=296, Percent_Identity=33.445945945946, Blast_Score=130, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6319593, Length=261, Percent_Identity=32.5670498084291, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI45551847, Length=278, Percent_Identity=33.4532374100719, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI45550715, Length=278, Percent_Identity=33.4532374100719, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24666278, Length=256, Percent_Identity=34.375, Blast_Score=138, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24645119, Length=216, Percent_Identity=37.962962962963, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 33345; Mature: 33214

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDIKTYPHDKKGELLELASIDQLDMMAIQVRRDIVRMLSMANSGHTGGSLGMADIFTA
CCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LYFRLIKHDPHNFWKQDDQDLVFLSNGHIAPVWYSVLARSGYFPLHELNSLRQISSYLQG
HHHHHHHCCCHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
HPTSEAKLPGIRIASGSLGQGLSAAAGAALGLRLDNKNNDIYCLMGDGECQEGQIWEAAM
CCCCCCCCCCEEEECCCCCCCCHHHCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHHH
SAAHYDLGNLIGIVDCNSLQIDGEVQSVMSLEPFGDKWRAFGWEVYHCDGNDIEDVIASI
HHHHCCHHCEEEEEECCCEEECCHHHHHHHCCCCCCCHHHCCEEEEECCCCCHHHHHHHH
SRIRDRDDRKSPAVLLATTIMGKGVPFFEGSMPDKSNWHGKPPSQDDAEKALAILGETVF
HHHHCCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
GDF
CCC
>Mature Secondary Structure 
AKDIKTYPHDKKGELLELASIDQLDMMAIQVRRDIVRMLSMANSGHTGGSLGMADIFTA
CCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LYFRLIKHDPHNFWKQDDQDLVFLSNGHIAPVWYSVLARSGYFPLHELNSLRQISSYLQG
HHHHHHHCCCHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
HPTSEAKLPGIRIASGSLGQGLSAAAGAALGLRLDNKNNDIYCLMGDGECQEGQIWEAAM
CCCCCCCCCCEEEECCCCCCCCHHHCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHHH
SAAHYDLGNLIGIVDCNSLQIDGEVQSVMSLEPFGDKWRAFGWEVYHCDGNDIEDVIASI
HHHHCCHHCEEEEEECCCEEECCHHHHHHHCCCCCCCHHHCCEEEEECCCCCHHHHHHHH
SRIRDRDDRKSPAVLLATTIMGKGVPFFEGSMPDKSNWHGKPPSQDDAEKALAILGETVF
HHHHCCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
GDF
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]