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The map label for this gene is trpF

Identifier: 119356748

GI number: 119356748

Start: 1047476

End: 1048123

Strand: Reverse

Name: trpF

Synonym: Cpha266_0920

Alternate gene names: 119356748

Gene position: 1048123-1047476 (Counterclockwise)

Preceding gene: 119356749

Following gene: 119356746

Centisome position: 33.44

GC content: 51.23

Gene sequence:

>648_bases
ATGGTTAAAATCAAAATCTGTGGAATAACCCGCTTGTCGGATGCCCTTGATGCATGCTTTGCCGGTGCGGATGCACTGGG
TTTCAATTTCAGCAGCAAGAGCCCGAGGGCCATAGCTCCTGAACGGGCAAAGGAGATCATCGAAAAACTGCCACCGTTCG
TTGAATCGACAGGAATATTTGTCGATCAGTCACCCGAAGAGATTAATGCCCTGTGCCAATACTGCAGGCTTCAGATTGCG
CAATTGCACAGCGAGCAGTACAGCCCTGAGCAAGCACGGTCAATAACGGCGGCAAAGGTAATCAAGGTTTTTCGGCCTGA
AGAAAATTTTGCAGTGGAGGAGGTATTTGCATTTGCTCAAAACAGCGGGATCAACGCCTTCCTGTTCGATGCTTACCGTC
CTGGCATGGCAGGCGGAACAGGCGAGACTATCGAAGCATCTCTTGCAACCCGTATCTTCAATGAACTCGGCAACTCCTGT
TATGCCATACTGGCTGGAGGGTTGAACGCGACCAACGTTGGCGAAGCAATTCGCCGTATTCAACCCTATGGCGTCGATAC
CGCAAGCGGAGTCGAAAGCCGGCCAGGCATCAAGGATAGCAGGGAAATCCGCTCATTTGTCAAGGCTGTACACCATGGTG
GCCATTAA

Upstream 100 bases:

>100_bases
AAACCGGAATAAACAAGTACCTCGGCCAGAGCATCCGGTTTTTTTATGATTAGCCGTATATTCCACAATTCGGAACGCCT
CTAACTGGTTGAACGCTACT

Downstream 100 bases:

>100_bases
TGGCCACTGCAAGCCTCCACCTGTTCAAAAATAAGTTCCGAAGCCGTTTCAGGCAATTCGACCGTAATCAAATGGCCACA
TTCAGGCACTTCGACATAGT

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MVKIKICGITRLSDALDACFAGADALGFNFSSKSPRAIAPERAKEIIEKLPPFVESTGIFVDQSPEEINALCQYCRLQIA
QLHSEQYSPEQARSITAAKVIKVFRPEENFAVEEVFAFAQNSGINAFLFDAYRPGMAGGTGETIEASLATRIFNELGNSC
YAILAGGLNATNVGEAIRRIQPYGVDTASGVESRPGIKDSREIRSFVKAVHHGGH

Sequences:

>Translated_215_residues
MVKIKICGITRLSDALDACFAGADALGFNFSSKSPRAIAPERAKEIIEKLPPFVESTGIFVDQSPEEINALCQYCRLQIA
QLHSEQYSPEQARSITAAKVIKVFRPEENFAVEEVFAFAQNSGINAFLFDAYRPGMAGGTGETIEASLATRIFNELGNSC
YAILAGGLNATNVGEAIRRIQPYGVDTASGVESRPGIKDSREIRSFVKAVHHGGH
>Mature_215_residues
MVKIKICGITRLSDALDACFAGADALGFNFSSKSPRAIAPERAKEIIEKLPPFVESTGIFVDQSPEEINALCQYCRLQIA
QLHSEQYSPEQARSITAAKVIKVFRPEENFAVEEVFAFAQNSGINAFLFDAYRPGMAGGTGETIEASLATRIFNELGNSC
YAILAGGLNATNVGEAIRRIQPYGVDTASGVESRPGIKDSREIRSFVKAVHHGGH

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family

Homologues:

Organism=Saccharomyces cerevisiae, GI6320210, Length=216, Percent_Identity=31.9444444444444, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRPF_CHLPD (A1BEZ1)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_911392.1
- ProteinModelPortal:   A1BEZ1
- SMR:   A1BEZ1
- STRING:   A1BEZ1
- GeneID:   4570553
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0920
- NMPDR:   fig|290317.7.peg.977
- eggNOG:   COG0135
- HOGENOM:   HBG554803
- OMA:   SKICGIT
- ProtClustDB:   CLSK637437
- HAMAP:   MF_00135_B
- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF00697 PRAI; SSF51366 RibP_bind_barrel

EC number: =5.3.1.24

Molecular weight: Translated: 23257; Mature: 23257

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKIKICGITRLSDALDACFAGADALGFNFSSKSPRAIAPERAKEIIEKLPPFVESTGIF
CEEEEEECCHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCE
VDQSPEEINALCQYCRLQIAQLHSEQYSPEQARSITAAKVIKVFRPEENFAVEEVFAFAQ
EECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
NSGINAFLFDAYRPGMAGGTGETIEASLATRIFNELGNSCYAILAGGLNATNVGEAIRRI
CCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEHHCCCCCCCHHHHHHHHH
QPYGVDTASGVESRPGIKDSREIRSFVKAVHHGGH
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVKIKICGITRLSDALDACFAGADALGFNFSSKSPRAIAPERAKEIIEKLPPFVESTGIF
CEEEEEECCHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCE
VDQSPEEINALCQYCRLQIAQLHSEQYSPEQARSITAAKVIKVFRPEENFAVEEVFAFAQ
EECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
NSGINAFLFDAYRPGMAGGTGETIEASLATRIFNELGNSCYAILAGGLNATNVGEAIRRI
CCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEHHCCCCCCCHHHHHHHHH
QPYGVDTASGVESRPGIKDSREIRSFVKAVHHGGH
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA