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The map label for this gene is ald [H]

Identifier: 119356734

GI number: 119356734

Start: 1035739

End: 1036842

Strand: Direct

Name: ald [H]

Synonym: Cpha266_0906

Alternate gene names: 119356734

Gene position: 1035739-1036842 (Clockwise)

Preceding gene: 119356732

Following gene: 119356736

Centisome position: 33.05

GC content: 54.62

Gene sequence:

>1104_bases
ATGAATATCGGAATTCCAAAAGAGATCAAAAACAGGGAGAGCAGAGTCTCTTGCACACCATCCGGAGTGCGCCATCTGGT
CAATGCCGGCCATCATGTTGCTGTTGAAAAGGGCGCAGGTGAAGGGAGCGGCTTCAGCGACGACAAGTACCGGCGAGCGG
GAGCAATGGTTGAACCATCTGCGGAAAAAGTATGGCAGAACGAACTTGTTGTGAAGGTCAAGGAGCCACTCAGCGAGGAG
TTCGGTTATTTAAGGGACGATCTCATTCTTTTTACCTTTCTGCATCTTGCCGGTAATGCCGGGTTGACGGAGCAGCTTCT
TGCTGCCGGAACAACCGCTCTTGCCTATGAAACCGTTCAGGAGGGCGGACGTCTGCCTCTGCTTGCTCCTATGAGCGAGA
TTGCCGGAAAGATGAGTGTTCTCATGGGCGCTTATTATCTGGGTTTTCAGCATGGCGGCGAGGGCAAACTGCTGGGCGGT
GTTCCCGGTGTTTTGCCGGGCAAGGTGGTTGTTCTTGGCGGAGGATCGGCCGGTATGCATGCTGCAAAGGTTGCCGCAGG
TCTTGGAGCGGATGTGACCTTGCTTGAGCTTGACCAGGAGCGTTTGCGCGCGCTTGAATCAGTTCTCCCGTCGCAGGTGC
ATACCCTCTACTCAACCGAACAGCATATTGATGAACAGCTTGAGGTAGCCGATGTGCTTATCGGCGCTGTGCTTGTTCCC
GGTGCAACCGCCCCGAAACTGGTCAGTCGAAGGATGCTGCAGCGAATAAAACCCGGCGCAGTGCTGGTGGATATCGCCAT
TGATCAGGGTGGATGTTTCGCCTCTTCACGGCCGACCACCCATGAAGATCCTGTGTTTCTTGAAGAGAGCGTTGTTCACT
ACTGTGTTGCCAATATGCCGGCGGCATACCCTCAAACCTCAACAGAAGCCCTTGCCGGAGCTTCGTTGCCCTATATCAGA
AGGATAGCCGATCTCGGTCTCGCAAGTGCCACGGTTATCATGCCCGGCCTTGCCGGAGGTCTCAACACGTGGCAGGGCCA
CATTACCCATGAAGCGCTTGCGAACTCTCTGGGCAAACCTTATTTCGAAAACCCGTTCAGGTAG

Upstream 100 bases:

>100_bases
TGAAATGGTTACATTGCTTTCAGGGCTTTTTATCGTTTTTATTGCTGCTCAACCGTTTGATGGTTGGGAGAAACCGGCTT
TATAGAGGAGAGTTGCCGTT

Downstream 100 bases:

>100_bases
GTTCCGGTATATATCAGGGTTCAAGCAGCTTGAATCCTGATTCCTGATCCATGATGCGGGATGCGGATGTATCAAGCAGC
TCTGTCAGAATAACCTCCAT

Product: L-alanine dehydrogenase

Products: NA

Alternate protein names: 40 kDa antigen; TB43 [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MNIGIPKEIKNRESRVSCTPSGVRHLVNAGHHVAVEKGAGEGSGFSDDKYRRAGAMVEPSAEKVWQNELVVKVKEPLSEE
FGYLRDDLILFTFLHLAGNAGLTEQLLAAGTTALAYETVQEGGRLPLLAPMSEIAGKMSVLMGAYYLGFQHGGEGKLLGG
VPGVLPGKVVVLGGGSAGMHAAKVAAGLGADVTLLELDQERLRALESVLPSQVHTLYSTEQHIDEQLEVADVLIGAVLVP
GATAPKLVSRRMLQRIKPGAVLVDIAIDQGGCFASSRPTTHEDPVFLEESVVHYCVANMPAAYPQTSTEALAGASLPYIR
RIADLGLASATVIMPGLAGGLNTWQGHITHEALANSLGKPYFENPFR

Sequences:

>Translated_367_residues
MNIGIPKEIKNRESRVSCTPSGVRHLVNAGHHVAVEKGAGEGSGFSDDKYRRAGAMVEPSAEKVWQNELVVKVKEPLSEE
FGYLRDDLILFTFLHLAGNAGLTEQLLAAGTTALAYETVQEGGRLPLLAPMSEIAGKMSVLMGAYYLGFQHGGEGKLLGG
VPGVLPGKVVVLGGGSAGMHAAKVAAGLGADVTLLELDQERLRALESVLPSQVHTLYSTEQHIDEQLEVADVLIGAVLVP
GATAPKLVSRRMLQRIKPGAVLVDIAIDQGGCFASSRPTTHEDPVFLEESVVHYCVANMPAAYPQTSTEALAGASLPYIR
RIADLGLASATVIMPGLAGGLNTWQGHITHEALANSLGKPYFENPFR
>Mature_367_residues
MNIGIPKEIKNRESRVSCTPSGVRHLVNAGHHVAVEKGAGEGSGFSDDKYRRAGAMVEPSAEKVWQNELVVKVKEPLSEE
FGYLRDDLILFTFLHLAGNAGLTEQLLAAGTTALAYETVQEGGRLPLLAPMSEIAGKMSVLMGAYYLGFQHGGEGKLLGG
VPGVLPGKVVVLGGGSAGMHAAKVAAGLGADVTLLELDQERLRALESVLPSQVHTLYSTEQHIDEQLEVADVLIGAVLVP
GATAPKLVSRRMLQRIKPGAVLVDIAIDQGGCFASSRPTTHEDPVFLEESVVHYCVANMPAAYPQTSTEALAGASLPYIR
RIADLGLASATVIMPGLAGGLNTWQGHITHEALANSLGKPYFENPFR

Specific function: May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=332, Percent_Identity=31.9277108433735, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI122939153, Length=332, Percent_Identity=31.9277108433735, Blast_Score=151, Evalue=7e-37,
Organism=Escherichia coli, GI1787887, Length=343, Percent_Identity=31.4868804664723, Blast_Score=140, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17550456, Length=333, Percent_Identity=31.5315315315315, Blast_Score=146, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 38843; Mature: 38843

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGIPKEIKNRESRVSCTPSGVRHLVNAGHHVAVEKGAGEGSGFSDDKYRRAGAMVEPS
CCCCCCHHHHCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHCCCCCCCC
AEKVWQNELVVKVKEPLSEEFGYLRDDLILFTFLHLAGNAGLTEQLLAAGTTALAYETVQ
HHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHH
EGGRLPLLAPMSEIAGKMSVLMGAYYLGFQHGGEGKLLGGVPGVLPGKVVVLGGGSAGMH
CCCCCCEECCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEEECCCCCHH
AAKVAAGLGADVTLLELDQERLRALESVLPSQVHTLYSTEQHIDEQLEVADVLIGAVLVP
HHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GATAPKLVSRRMLQRIKPGAVLVDIAIDQGGCFASSRPTTHEDPVFLEESVVHYCVANMP
CCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
AAYPQTSTEALAGASLPYIRRIADLGLASATVIMPGLAGGLNTWQGHITHEALANSLGKP
CCCCCCCHHHHHCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCC
YFENPFR
CCCCCCC
>Mature Secondary Structure
MNIGIPKEIKNRESRVSCTPSGVRHLVNAGHHVAVEKGAGEGSGFSDDKYRRAGAMVEPS
CCCCCCHHHHCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHCCCCCCCC
AEKVWQNELVVKVKEPLSEEFGYLRDDLILFTFLHLAGNAGLTEQLLAAGTTALAYETVQ
HHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHH
EGGRLPLLAPMSEIAGKMSVLMGAYYLGFQHGGEGKLLGGVPGVLPGKVVVLGGGSAGMH
CCCCCCEECCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEEECCCCCHH
AAKVAAGLGADVTLLELDQERLRALESVLPSQVHTLYSTEQHIDEQLEVADVLIGAVLVP
HHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GATAPKLVSRRMLQRIKPGAVLVDIAIDQGGCFASSRPTTHEDPVFLEESVVHYCVANMP
CCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
AAYPQTSTEALAGASLPYIRRIADLGLASATVIMPGLAGGLNTWQGHITHEALANSLGKP
CCCCCCCHHHHHCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCC
YFENPFR
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1587598; 9634230; 12218036; 7822223 [H]