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The map label for this gene is guaA [H]

Identifier: 119356670

GI number: 119356670

Start: 953988

End: 954719

Strand: Direct

Name: guaA [H]

Synonym: Cpha266_0839

Alternate gene names: 119356670

Gene position: 953988-954719 (Clockwise)

Preceding gene: 119356666

Following gene: 119356674

Centisome position: 30.44

GC content: 56.42

Gene sequence:

>732_bases
ATGAAAAAGCTTTACATCATCAAAGCCGGTTCGACCTTCGCTTCCACGATTGCGGAGCTTGGCGATTTCGAAGCGTGGAT
TATTCGGGCGCTTGGAACGCTATCAATTCCCGTTGAGGTGGTAAATGCGGTGCATGGCGAACCGCTTCCGCTGCCCGACG
AGTGCTGCGGTGTGCTTGTTACCGGTTCACATGCCATGGTTACCCAAAACCTCCCGTGGAGCGTCGGGATCGAATCGTGG
ATTCCTCTGCTGGTCGGAGCAGGGGTTCCGTTTCTGGGTATCTGTTACGGCCACCAGCTTCTCGGAAGGGCTATGGGAGG
AAAGGTCGGCTACCATCCAAAAGGCAGCGAAACCGGTACGGTTACGCTTACCCTTACGACGGAAGCGGGTGACGATCTAC
TTTTTCAGCATATCCCTTCAACCTTCAGGGCTCATGCAACTCATGCTCAGAGTGTGCTGGAGCTGCCGCCCGGCGCGGTC
ACTCTTGCCCGGAATGCGCACGATCCGCACCATGCGTTTCGCGTCGGAACCGCTGCATGGGGTGTGCAGTTTCATCCCGA
ATACACCGCAGCCGTGATGCAGGCCTACATCAATGCCGATTGTGATTCACTTTCCCGTAGCGGCTGCGATGTGTCTGCAC
TGCTCCGGGAGGTAACGCATACTCCTGAAGCATCAGGCATTCTCCGCAAGTTTGCCGTCCATGTCGAACGATCTTGCACC
GCTGAAGGGTAG

Upstream 100 bases:

>100_bases
CAAGGTACAACGAAGCCTGAAAGCTTTCATGCTTTTGCCGAACCTTGTTTGTGCAACAGGCTGAAAAACAATAGATTCAC
AAAAAACTGTCAAAAGAGCG

Downstream 100 bases:

>100_bases
CAGCGAGCAATACCCTGTTCCGTTTATGCGTGTTAACTTCGGTCAAGTAGCGCAACAGGTAAACGATTCAAAGAAAAATA
ACTCAAACAACTCCCTTTTT

Product: glutamine amidotransferase

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKKLYIIKAGSTFASTIAELGDFEAWIIRALGTLSIPVEVVNAVHGEPLPLPDECCGVLVTGSHAMVTQNLPWSVGIESW
IPLLVGAGVPFLGICYGHQLLGRAMGGKVGYHPKGSETGTVTLTLTTEAGDDLLFQHIPSTFRAHATHAQSVLELPPGAV
TLARNAHDPHHAFRVGTAAWGVQFHPEYTAAVMQAYINADCDSLSRSGCDVSALLREVTHTPEASGILRKFAVHVERSCT
AEG

Sequences:

>Translated_243_residues
MKKLYIIKAGSTFASTIAELGDFEAWIIRALGTLSIPVEVVNAVHGEPLPLPDECCGVLVTGSHAMVTQNLPWSVGIESW
IPLLVGAGVPFLGICYGHQLLGRAMGGKVGYHPKGSETGTVTLTLTTEAGDDLLFQHIPSTFRAHATHAQSVLELPPGAV
TLARNAHDPHHAFRVGTAAWGVQFHPEYTAAVMQAYINADCDSLSRSGCDVSALLREVTHTPEASGILRKFAVHVERSCT
AEG
>Mature_243_residues
MKKLYIIKAGSTFASTIAELGDFEAWIIRALGTLSIPVEVVNAVHGEPLPLPDECCGVLVTGSHAMVTQNLPWSVGIESW
IPLLVGAGVPFLGICYGHQLLGRAMGGKVGYHPKGSETGTVTLTLTTEAGDDLLFQHIPSTFRAHATHAQSVLELPPGAV
TLARNAHDPHHAFRVGTAAWGVQFHPEYTAAVMQAYINADCDSLSRSGCDVSALLREVTHTPEASGILRKFAVHVERSCT
AEG

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG0518

COG function: function code F; GMP synthase - Glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GMP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR004739
- InterPro:   IPR022955
- InterPro:   IPR022310
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00117 GATase; PF00958 GMP_synt_C; PF02540 NAD_synthase [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 25842; Mature: 25842

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLYIIKAGSTFASTIAELGDFEAWIIRALGTLSIPVEVVNAVHGEPLPLPDECCGVLV
CCEEEEEECCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHCCEEE
TGSHAMVTQNLPWSVGIESWIPLLVGAGVPFLGICYGHQLLGRAMGGKVGYHPKGSETGT
ECCCEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
VTLTLTTEAGDDLLFQHIPSTFRAHATHAQSVLELPPGAVTLARNAHDPHHAFRVGTAAW
EEEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHEEECHHHC
GVQFHPEYTAAVMQAYINADCDSLSRSGCDVSALLREVTHTPEASGILRKFAVHVERSCT
CEEECCHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
AEG
CCC
>Mature Secondary Structure
MKKLYIIKAGSTFASTIAELGDFEAWIIRALGTLSIPVEVVNAVHGEPLPLPDECCGVLV
CCEEEEEECCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHCCEEE
TGSHAMVTQNLPWSVGIESWIPLLVGAGVPFLGICYGHQLLGRAMGGKVGYHPKGSETGT
ECCCEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
VTLTLTTEAGDDLLFQHIPSTFRAHATHAQSVLELPPGAVTLARNAHDPHHAFRVGTAAW
EEEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHEEECHHHC
GVQFHPEYTAAVMQAYINADCDSLSRSGCDVSALLREVTHTPEASGILRKFAVHVERSCT
CEEECCHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
AEG
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA