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The map label for this gene is coaX [H]

Identifier: 119356666

GI number: 119356666

Start: 948965

End: 949771

Strand: Direct

Name: coaX [H]

Synonym: Cpha266_0835

Alternate gene names: 119356666

Gene position: 948965-949771 (Clockwise)

Preceding gene: 119356665

Following gene: 119356670

Centisome position: 30.28

GC content: 51.8

Gene sequence:

>807_bases
ATGTCAGCTTCTGTTCCAGTTTCGCTTCTTCTTGTCGTTGAAATCGGCAATACGACAACTTCTTTTGTCGTTCTCGATGG
CGATGAGTGTCTTGTGGTGAAAAGTCTTCTGACCGCCGCGCTTGATGAGGCAGGTCTGGTGTCCGGTATCTTTTCAGAGC
TTCGGGGAGCCTTTAAAGAGTTGAAGGATGTCGTCGTATGCAGCGTTGTTCCCGCTGCGACCAGAGTGATTCAGCGGCAT
CTGCAGAAACGTCTTGCCGGTTTGTTTTTTTCCGTTACGTCGAGTATCACCCTGCCCTTTACCCTTGATTATGATATTCC
TGAATCGTTCGGTGCCGATCGACTTGCCCTGTGTGCACTCTCCCGGTATCGCTATCCCGATCGCGCGGTCATTGCCCTTG
ATATAGGTACGGCCCTGACATTTGATGTGCTTGGTTCAAACGGCGACTATCTTGGTGGTCTTATCATGCCCGGACTTGAG
ATGCGCTCCAGGGCGCTGCACGAACGCACGGCACAGCTTCCGCTTGTCGGGATTGAACGTTCAGCAACGCTTATCGGACG
TTCGACAAAGGAGTGCATCATGAACGGTATTTTCTGGGGTTGTGTATCGGAGATCGAAGGGTTGATCTCAAAAATAGAAC
GTCATGTGCAGGAGACCTATGGTGAAGAGCGTCCGGTGGTGATTGCAACCGGAGGAAGCGCACCCCTGATTGCAGGATTG
CTCGATTCGCTGACGCTGCATGACGAATATGCCGTGATCAGGGGCGCAGGATATCTCTTCAGGCTTAACAGGCCAACGCT
TTTTTGA

Upstream 100 bases:

>100_bases
ATCTGAAGGATTATCAGGAGTTTCTTTCAGCACTATCGGCACGAACCGGAGTTGCTGTAAAATTGCCATAACCGGCAGCT
CTCACCGAGAGGGAATTTTC

Downstream 100 bases:

>100_bases
AGAGCTCCTTTGCCTCCGTTATTGCTTTGAGAACATGGTGGTCTTCAACGGTTTCTTCAAGCAGAAATGCCGACCCGAGA
CTTTTCAGCAGGACAAACCG

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSASVPVSLLLVVEIGNTTTSFVVLDGDECLVVKSLLTAALDEAGLVSGIFSELRGAFKELKDVVVCSVVPAATRVIQRH
LQKRLAGLFFSVTSSITLPFTLDYDIPESFGADRLALCALSRYRYPDRAVIALDIGTALTFDVLGSNGDYLGGLIMPGLE
MRSRALHERTAQLPLVGIERSATLIGRSTKECIMNGIFWGCVSEIEGLISKIERHVQETYGEERPVVIATGGSAPLIAGL
LDSLTLHDEYAVIRGAGYLFRLNRPTLF

Sequences:

>Translated_268_residues
MSASVPVSLLLVVEIGNTTTSFVVLDGDECLVVKSLLTAALDEAGLVSGIFSELRGAFKELKDVVVCSVVPAATRVIQRH
LQKRLAGLFFSVTSSITLPFTLDYDIPESFGADRLALCALSRYRYPDRAVIALDIGTALTFDVLGSNGDYLGGLIMPGLE
MRSRALHERTAQLPLVGIERSATLIGRSTKECIMNGIFWGCVSEIEGLISKIERHVQETYGEERPVVIATGGSAPLIAGL
LDSLTLHDEYAVIRGAGYLFRLNRPTLF
>Mature_267_residues
SASVPVSLLLVVEIGNTTTSFVVLDGDECLVVKSLLTAALDEAGLVSGIFSELRGAFKELKDVVVCSVVPAATRVIQRHL
QKRLAGLFFSVTSSITLPFTLDYDIPESFGADRLALCALSRYRYPDRAVIALDIGTALTFDVLGSNGDYLGGLIMPGLEM
RSRALHERTAQLPLVGIERSATLIGRSTKECIMNGIFWGCVSEIEGLISKIERHVQETYGEERPVVIATGGSAPLIAGLL
DSLTLHDEYAVIRGAGYLFRLNRPTLF

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 28963; Mature: 28832

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASVPVSLLLVVEIGNTTTSFVVLDGDECLVVKSLLTAALDEAGLVSGIFSELRGAFKE
CCCCCCEEEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKDVVVCSVVPAATRVIQRHLQKRLAGLFFSVTSSITLPFTLDYDIPESFGADRLALCAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHH
SRYRYPDRAVIALDIGTALTFDVLGSNGDYLGGLIMPGLEMRSRALHERTAQLPLVGIER
HHCCCCCCEEEEEECCCEEEEEEECCCCCEECHHHCCCHHHHHHHHHHHHHCCCEEECCC
SATLIGRSTKECIMNGIFWGCVSEIEGLISKIERHVQETYGEERPVVIATGGSAPLIAGL
CHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHH
LDSLTLHDEYAVIRGAGYLFRLNRPTLF
HHHHHCCCCCEEEECCCEEEEECCCCCC
>Mature Secondary Structure 
SASVPVSLLLVVEIGNTTTSFVVLDGDECLVVKSLLTAALDEAGLVSGIFSELRGAFKE
CCCCCEEEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKDVVVCSVVPAATRVIQRHLQKRLAGLFFSVTSSITLPFTLDYDIPESFGADRLALCAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHH
SRYRYPDRAVIALDIGTALTFDVLGSNGDYLGGLIMPGLEMRSRALHERTAQLPLVGIER
HHCCCCCCEEEEEECCCEEEEEEECCCCCEECHHHCCCHHHHHHHHHHHHHCCCEEECCC
SATLIGRSTKECIMNGIFWGCVSEIEGLISKIERHVQETYGEERPVVIATGGSAPLIAGL
CHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHH
LDSLTLHDEYAVIRGAGYLFRLNRPTLF
HHHHHCCCCCEEEECCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]