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The map label for this gene is ziaR [H]

Identifier: 119356591

GI number: 119356591

Start: 861125

End: 861493

Strand: Reverse

Name: ziaR [H]

Synonym: Cpha266_0758

Alternate gene names: 119356591

Gene position: 861493-861125 (Counterclockwise)

Preceding gene: 119356592

Following gene: 119356590

Centisome position: 27.49

GC content: 54.2

Gene sequence:

>369_bases
ATGCAGGAGCATGAACACGACCGCTGCGAAGAGCAGTGCATTCATCCGGAGGTGATCGAATCAGTACGGAGGGAGATGCT
GGGTGCCGTTCCGGCGGATGAGCTTGCGCAACTGTTCAAGGTGCTTGGCGACAATACAAGGATACGGATACTCGATGCGC
TTTTCCGGTCGGAGCTTTGCGTTTGCGACCTGACCGCGCTGCTCGGCATGAACCAGTCGGCAGTGTCGCATCAGCTCAGG
GTGCTGCGTGATGCAAGAATCGTGAAATCGAAAAAACAGGGTAAAAATGTACTGTACAGCCTGGACGACGATCACATATC
GGAACTTGTCCGCATGGGTTCGGAACATGTTCGGGAGCTGAGACGATAA

Upstream 100 bases:

>100_bases
GAGGGATGGAAAAGGATATGCTCCGTACCTTTTTTTGTTGACAGGGCGGCAATAATTTGTTATCATATGAATGATTGTTC
ATATATAAAAAGGAAATCGA

Downstream 100 bases:

>100_bases
TGCGCTTTTCAGAGAGGGAGCATCAAAAGTTATGACGCATCCGGTTTGCTGCGTTGGTCAGGTGGTCGAAATCCTCATCC
CGACTTTTCGGAACTCCGTT

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MQEHEHDRCEEQCIHPEVIESVRREMLGAVPADELAQLFKVLGDNTRIRILDALFRSELCVCDLTALLGMNQSAVSHQLR
VLRDARIVKSKKQGKNVLYSLDDDHISELVRMGSEHVRELRR

Sequences:

>Translated_122_residues
MQEHEHDRCEEQCIHPEVIESVRREMLGAVPADELAQLFKVLGDNTRIRILDALFRSELCVCDLTALLGMNQSAVSHQLR
VLRDARIVKSKKQGKNVLYSLDDDHISELVRMGSEHVRELRR
>Mature_122_residues
MQEHEHDRCEEQCIHPEVIESVRREMLGAVPADELAQLFKVLGDNTRIRILDALFRSELCVCDLTALLGMNQSAVSHQLR
VLRDARIVKSKKQGKNVLYSLDDDHISELVRMGSEHVRELRR

Specific function: Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ziaA-mediated efflux of excess zinc into the periplasm [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 14059; Mature: 14059

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEHEHDRCEEQCIHPEVIESVRREMLGAVPADELAQLFKVLGDNTRIRILDALFRSELC
CCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VCDLTALLGMNQSAVSHQLRVLRDARIVKSKKQGKNVLYSLDDDHISELVRMGSEHVREL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHCHHHHHHH
RR
HC
>Mature Secondary Structure
MQEHEHDRCEEQCIHPEVIESVRREMLGAVPADELAQLFKVLGDNTRIRILDALFRSELC
CCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VCDLTALLGMNQSAVSHQLRVLRDARIVKSKKQGKNVLYSLDDDHISELVRMGSEHVREL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHCHHHHHHH
RR
HC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9724772 [H]