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The map label for this gene is hypD [H]

Identifier: 119356558

GI number: 119356558

Start: 825541

End: 826632

Strand: Direct

Name: hypD [H]

Synonym: Cpha266_0724

Alternate gene names: 119356558

Gene position: 825541-826632 (Clockwise)

Preceding gene: 119356557

Following gene: 119356559

Centisome position: 26.34

GC content: 52.47

Gene sequence:

>1092_bases
ATGAAGTTTATTGACGAGTACCGCGATCCGAAGCTTGCCCTTGCCATTCTTGAAGAGATCAGGAGAAAAACGACAAGAGC
ATGGACTATCATGGAGATATGCGGCGGACAGACCCATTCCATCATACGTAATGGGATTGATCAGCTTCTGCCCGATGCTA
TAACGCTGGCGCATGGACCGGGATGTCCGGTTTGCGTCACTCCCCTTGAAACTATCGAGAGAGCTTTGCTTCTCGCCGGC
ATGCCCGAGGTGATTCTTGCAAGTTTCGGGGACATGCTACGGGTGCCCGGCAGTTCCAAAGATCTCTTTCTCGTGCGCAG
CGAGGGCGGCGATGTGCGTTTTGTGTTTTCTCCGCTGGATGCTCTGCAGATTGCGCGTGATAATCCTCATAAAGAGGTGG
TGTTTCTTGCTGTCGGCTTTGAAACAACAGCGCCTGCAAATGCCATGGCGGCTTATCAGGCCAAGCGGGAAGGTATCGGA
AATTTCAGTCTGCTGGTAAGTCAGGTGATGGTTCCTCCCGCAATGAGAGCAATTCTCTCTTCTCCGGACAATAAGGTTGA
GGGTTTTCTTGCGGCAGGTCATGTGTGCGCGGTTATGGGGTATGAAGAGTATGAGGCTGTTTCAGGAGAGTTTCATGTTC
CCATTGTTCCGACCGGCTTTGAGCCGGTTGATCTTCTTGCCGGAATTCTGAAAACCATTGAACTGCTTGAAGATCAAAAG
GCGGAAGTGTTCAACCGTTATGGTCGGGTGGTGAGTCGTGAGGGTAATCTTGCCGCAAGGAGGCTCATGGACTCGGTGTA
TATGGTCAGTGACCGTCAGTGGCGAGGGATTGGTTTAATCCCGAAAAGCGGGCTTGCCCTTCGGGAAGAGTATGCTGCCT
GGGATGCCGAAAAAAAATTCGATCTATCCCATATCACTGCCGGCGAATCGCCCCTCTGCATGAGCGGCAGCGTGCTGCGG
GGAGTGCTGAAACCGGACGCCTGTCCTGCATTCGGACGCGAGTGCAATCCACAGCACCCTCTTGGAGCGACAATGGTTTC
TTCGGAAGGTGCTTGTGCCGCATACTATAACTACCATCGTAACCCATTTTAG

Upstream 100 bases:

>100_bases
GAAAGTCTGAAGCTCTGGCAGGATCTTGTCGAGAGCGGAGCTTTTGATGATCCGGATGATGAACTTCCATCCCCGGAAAC
GATATGATGGTGCTTTGGTT

Downstream 100 bases:

>100_bases
TTATGACGATTGAATTGAGCTGTCCTGTTCCGATCAGCAATCATGAGACTGTCCAGATGGCCCATGGCGCGGGAGGAAGG
CTCTCGCAGGATCTCATGCG

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MKFIDEYRDPKLALAILEEIRRKTTRAWTIMEICGGQTHSIIRNGIDQLLPDAITLAHGPGCPVCVTPLETIERALLLAG
MPEVILASFGDMLRVPGSSKDLFLVRSEGGDVRFVFSPLDALQIARDNPHKEVVFLAVGFETTAPANAMAAYQAKREGIG
NFSLLVSQVMVPPAMRAILSSPDNKVEGFLAAGHVCAVMGYEEYEAVSGEFHVPIVPTGFEPVDLLAGILKTIELLEDQK
AEVFNRYGRVVSREGNLAARRLMDSVYMVSDRQWRGIGLIPKSGLALREEYAAWDAEKKFDLSHITAGESPLCMSGSVLR
GVLKPDACPAFGRECNPQHPLGATMVSSEGACAAYYNYHRNPF

Sequences:

>Translated_363_residues
MKFIDEYRDPKLALAILEEIRRKTTRAWTIMEICGGQTHSIIRNGIDQLLPDAITLAHGPGCPVCVTPLETIERALLLAG
MPEVILASFGDMLRVPGSSKDLFLVRSEGGDVRFVFSPLDALQIARDNPHKEVVFLAVGFETTAPANAMAAYQAKREGIG
NFSLLVSQVMVPPAMRAILSSPDNKVEGFLAAGHVCAVMGYEEYEAVSGEFHVPIVPTGFEPVDLLAGILKTIELLEDQK
AEVFNRYGRVVSREGNLAARRLMDSVYMVSDRQWRGIGLIPKSGLALREEYAAWDAEKKFDLSHITAGESPLCMSGSVLR
GVLKPDACPAFGRECNPQHPLGATMVSSEGACAAYYNYHRNPF
>Mature_363_residues
MKFIDEYRDPKLALAILEEIRRKTTRAWTIMEICGGQTHSIIRNGIDQLLPDAITLAHGPGCPVCVTPLETIERALLLAG
MPEVILASFGDMLRVPGSSKDLFLVRSEGGDVRFVFSPLDALQIARDNPHKEVVFLAVGFETTAPANAMAAYQAKREGIG
NFSLLVSQVMVPPAMRAILSSPDNKVEGFLAAGHVCAVMGYEEYEAVSGEFHVPIVPTGFEPVDLLAGILKTIELLEDQK
AEVFNRYGRVVSREGNLAARRLMDSVYMVSDRQWRGIGLIPKSGLALREEYAAWDAEKKFDLSHITAGESPLCMSGSVLR
GVLKPDACPAFGRECNPQHPLGATMVSSEGACAAYYNYHRNPF

Specific function: Required for the formation of all three hydrogenase isoenzymes [H]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=369, Percent_Identity=43.0894308943089, Blast_Score=338, Evalue=4e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 39682; Mature: 39682

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDEYRDPKLALAILEEIRRKTTRAWTIMEICGGQTHSIIRNGIDQLLPDAITLAHGP
CCCHHHHCCHHHHHHHHHHHHHHHHHHEEHHHHHCCCHHHHHHHHHHHHCCHHEEECCCC
GCPVCVTPLETIERALLLAGMPEVILASFGDMLRVPGSSKDLFLVRSEGGDVRFVFSPLD
CCCEEECCHHHHHHHHHHCCCHHHHHHHHHHHEECCCCCCCEEEEECCCCCEEEEECCHH
ALQIARDNPHKEVVFLAVGFETTAPANAMAAYQAKREGIGNFSLLVSQVMVPPAMRAILS
HHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHC
SPDNKVEGFLAAGHVCAVMGYEEYEAVSGEFHVPIVPTGFEPVDLLAGILKTIELLEDQK
CCCCHHHHHHHHCHHHEEECCHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
AEVFNRYGRVVSREGNLAARRLMDSVYMVSDRQWRGIGLIPKSGLALREEYAAWDAEKKF
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHCCCCCCC
DLSHITAGESPLCMSGSVLRGVLKPDACPAFGRECNPQHPLGATMVSSEGACAAYYNYHR
CHHHCCCCCCCCEECCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCC
NPF
CCC
>Mature Secondary Structure
MKFIDEYRDPKLALAILEEIRRKTTRAWTIMEICGGQTHSIIRNGIDQLLPDAITLAHGP
CCCHHHHCCHHHHHHHHHHHHHHHHHHEEHHHHHCCCHHHHHHHHHHHHCCHHEEECCCC
GCPVCVTPLETIERALLLAGMPEVILASFGDMLRVPGSSKDLFLVRSEGGDVRFVFSPLD
CCCEEECCHHHHHHHHHHCCCHHHHHHHHHHHEECCCCCCCEEEEECCCCCEEEEECCHH
ALQIARDNPHKEVVFLAVGFETTAPANAMAAYQAKREGIGNFSLLVSQVMVPPAMRAILS
HHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHC
SPDNKVEGFLAAGHVCAVMGYEEYEAVSGEFHVPIVPTGFEPVDLLAGILKTIELLEDQK
CCCCHHHHHHHHCHHHEEECCHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
AEVFNRYGRVVSREGNLAARRLMDSVYMVSDRQWRGIGLIPKSGLALREEYAAWDAEKKF
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHCCCCCCC
DLSHITAGESPLCMSGSVLRGVLKPDACPAFGRECNPQHPLGATMVSSEGACAAYYNYHR
CHHHCCCCCCCCEECCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCC
NPF
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]