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The map label for this gene is mtnA [H]

Identifier: 119356536

GI number: 119356536

Start: 801793

End: 802857

Strand: Reverse

Name: mtnA [H]

Synonym: Cpha266_0701

Alternate gene names: 119356536

Gene position: 802857-801793 (Counterclockwise)

Preceding gene: 119356537

Following gene: 119356535

Centisome position: 25.62

GC content: 51.36

Gene sequence:

>1065_bases
ATGATAGATGCCATTTCGTTCAATGAGGGTACGCTCCGCTACCTCGATCAGCGTTACCTTCCGCTCCGTGAAGAGCATAT
CTCGACAAAAGATCACCGGGAGGCGATAGAAGCCATTAAAACCCTTGCCGTACGAGGAGCGCCTCTTATCGGCGTTGCCG
CTGCCTATACGGTCATCCTCGGCATCAACAGCTACCGTGGTGATAAAGAGGGCTTCCCCTGCTTTTTCGGGAACCTGATT
GCCGATGTTGAAGCATCGCGCCCAACCGCGGTCAATCTCTTTTTTGCCACGAAAAAACTAAAAGCCGTATATGACAGGAA
CTTCAACAGCGATTCGCTTGAAGTGCTTTTTGCCAAAATGCTTTTCGAAGCACGACAGATCCACGATGACGAAATAGCCA
ATTGTGATGCCATGGCACAACACGGCGTTCGCCAGATCAGGGAAGATCTTGCTGAAATCCTGAAAACAAGAAAACTCAAT
GTGCTGACCCACTGCAACACCGGAACACTTGCCACCGGAGGCTCTGGAACGGCGCTCGGCGTCATCAAGCTTGCATGGCA
GGAGGGACTTATTGAAAAGGTCATTACCGCCGAAAGCCGCCCGCTTTTGCAGGGACTTCGTCTTACCGCCTGGGAACTTG
AACAGGAAAAAATACCCTTTTTCTCCATTTCAGACTCATCATCAGCCTTTCTCATGCAGCGCGGCATGATCGATTTCGGC
ATTGTCGGCGCTGACCGAATCGCTGCCAACGGCGATACAGCCAACAAGATCGGTACCTGCGCCCATGCGTTGAGCGCCTG
GCATCACAATATCCCGTTCTATATCGCAGCTCCGGTCTCAACCATTGATATCACGCTTTCCGACGGGACACAAATACCCA
TCGAAGAGCGCAGCGCCGATGAACTGAGAACCATTTTCGGCACCCAGGTTGCAACCTCGACTACACCGGTAATTAACTAT
GCTTTTGATGTCACTCCGGGAAAATTCCTCCGGGGAATCATCACGGACAAGAAAGCTGTAGTCGGAGACTATCTGAACGG
TCTTGGCCAACTGTTTGCAGAGTAA

Upstream 100 bases:

>100_bases
GAGGAGATTATTGAGGTTTCCAACCATGCAGAACCCAAAATGACCGCCATCTTCAAAGCCGTTGTCTCAAACCTCTAACC
CGATCAACATCATTTGACCC

Downstream 100 bases:

>100_bases
AACACCAGGCAAAAAGAAGACAACAAAAAAGATCGGAACGTTCTCTTGTTCCGATCTTTTTTGTTACAGCTCCATGGCGC
GGCGATGTTCTCTCTGTTCT

Product: translation initiation factor 2B subunit I

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MIDAISFNEGTLRYLDQRYLPLREEHISTKDHREAIEAIKTLAVRGAPLIGVAAAYTVILGINSYRGDKEGFPCFFGNLI
ADVEASRPTAVNLFFATKKLKAVYDRNFNSDSLEVLFAKMLFEARQIHDDEIANCDAMAQHGVRQIREDLAEILKTRKLN
VLTHCNTGTLATGGSGTALGVIKLAWQEGLIEKVITAESRPLLQGLRLTAWELEQEKIPFFSISDSSSAFLMQRGMIDFG
IVGADRIAANGDTANKIGTCAHALSAWHHNIPFYIAAPVSTIDITLSDGTQIPIEERSADELRTIFGTQVATSTTPVINY
AFDVTPGKFLRGIITDKKAVVGDYLNGLGQLFAE

Sequences:

>Translated_354_residues
MIDAISFNEGTLRYLDQRYLPLREEHISTKDHREAIEAIKTLAVRGAPLIGVAAAYTVILGINSYRGDKEGFPCFFGNLI
ADVEASRPTAVNLFFATKKLKAVYDRNFNSDSLEVLFAKMLFEARQIHDDEIANCDAMAQHGVRQIREDLAEILKTRKLN
VLTHCNTGTLATGGSGTALGVIKLAWQEGLIEKVITAESRPLLQGLRLTAWELEQEKIPFFSISDSSSAFLMQRGMIDFG
IVGADRIAANGDTANKIGTCAHALSAWHHNIPFYIAAPVSTIDITLSDGTQIPIEERSADELRTIFGTQVATSTTPVINY
AFDVTPGKFLRGIITDKKAVVGDYLNGLGQLFAE
>Mature_354_residues
MIDAISFNEGTLRYLDQRYLPLREEHISTKDHREAIEAIKTLAVRGAPLIGVAAAYTVILGINSYRGDKEGFPCFFGNLI
ADVEASRPTAVNLFFATKKLKAVYDRNFNSDSLEVLFAKMLFEARQIHDDEIANCDAMAQHGVRQIREDLAEILKTRKLN
VLTHCNTGTLATGGSGTALGVIKLAWQEGLIEKVITAESRPLLQGLRLTAWELEQEKIPFFSISDSSSAFLMQRGMIDFG
IVGADRIAANGDTANKIGTCAHALSAWHHNIPFYIAAPVSTIDITLSDGTQIPIEERSADELRTIFGTQVATSTTPVINY
AFDVTPGKFLRGIITDKKAVVGDYLNGLGQLFAE

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=340, Percent_Identity=37.9411764705882, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI23943880, Length=338, Percent_Identity=33.4319526627219, Blast_Score=149, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17557462, Length=336, Percent_Identity=36.9047619047619, Blast_Score=195, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6325375, Length=395, Percent_Identity=30.126582278481, Blast_Score=162, Evalue=9e-41,
Organism=Drosophila melanogaster, GI21357667, Length=351, Percent_Identity=35.8974358974359, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24651647, Length=351, Percent_Identity=35.8974358974359, Blast_Score=209, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 38810; Mature: 38810

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDAISFNEGTLRYLDQRYLPLREEHISTKDHREAIEAIKTLAVRGAPLIGVAAAYTVIL
CCCCEECCCCHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GINSYRGDKEGFPCFFGNLIADVEASRPTAVNLFFATKKLKAVYDRNFNSDSLEVLFAKM
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHCCCCCCHHHHHHHHHH
LFEARQIHDDEIANCDAMAQHGVRQIREDLAEILKTRKLNVLTHCNTGTLATGGSGTALG
HHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCCHH
VIKLAWQEGLIEKVITAESRPLLQGLRLTAWELEQEKIPFFSISDSSSAFLMQRGMIDFG
HHHHHHHHHHHHHHHHCCCCHHHHCCHHHHEECHHHCCCEEEECCCCCHHHHHCCCCCEE
IVGADRIAANGDTANKIGTCAHALSAWHHNIPFYIAAPVSTIDITLSDGTQIPIEERSAD
EECCCCEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCCCCCCCCHH
ELRTIFGTQVATSTTPVINYAFDVTPGKFLRGIITDKKAVVGDYLNGLGQLFAE
HHHHHHHCHHCCCCCCEEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDAISFNEGTLRYLDQRYLPLREEHISTKDHREAIEAIKTLAVRGAPLIGVAAAYTVIL
CCCCEECCCCHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GINSYRGDKEGFPCFFGNLIADVEASRPTAVNLFFATKKLKAVYDRNFNSDSLEVLFAKM
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHCCCCCCHHHHHHHHHH
LFEARQIHDDEIANCDAMAQHGVRQIREDLAEILKTRKLNVLTHCNTGTLATGGSGTALG
HHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCCHH
VIKLAWQEGLIEKVITAESRPLLQGLRLTAWELEQEKIPFFSISDSSSAFLMQRGMIDFG
HHHHHHHHHHHHHHHHCCCCHHHHCCHHHHEECHHHCCCEEEECCCCCHHHHHCCCCCEE
IVGADRIAANGDTANKIGTCAHALSAWHHNIPFYIAAPVSTIDITLSDGTQIPIEERSAD
EECCCCEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCCCCCCCCHH
ELRTIFGTQVATSTTPVINYAFDVTPGKFLRGIITDKKAVVGDYLNGLGQLFAE
HHHHHHHCHHCCCCCCEEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]