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The map label for this gene is ruvB

Identifier: 119356405

GI number: 119356405

Start: 636859

End: 637899

Strand: Direct

Name: ruvB

Synonym: Cpha266_0569

Alternate gene names: 119356405

Gene position: 636859-637899 (Clockwise)

Preceding gene: 119356404

Following gene: 119356406

Centisome position: 20.32

GC content: 47.93

Gene sequence:

>1041_bases
GTGAAAATCGAATTGTTAAATACCCCTGCTGATGCTCTTGAAATTCGTTATGAAGAGCAGATCCGTCCGCTGAAAATGGA
TGATTTTACTGGTCAGCAGCGATTGACCGATAATCTCAGGGTTTTTATTTCAGCGGCTAAAATAAGGGGAGATGCACTTG
ATCATGTGCTGCTTTCAGGCCCTCCAGGACTTGGTAAAACAACTCTTGCAAATATTATTGCATCAGAAATGGGCGGGAAT
ATCAAGGTAACTTCCGGTCCGATGCTTGATAAGGCAGGAAATCTTGCCGGTCTTTTGACAAGCCTTCGTAAGGGGGATGT
GCTTTTTATTGATGAGATTCATCGACTTCCCGCGGCTGTAGAGGAGTATCTTTATTCAGCTATGGAGGATTTCAGGATTG
ACATTATGCTTGATAGCGGGCCATCCGCACGTGCCGTACAGCTTCGCATAGAACCGTTCACCCTTGTGGGCGCAACAACC
CGTTCCGGACTGCTCACCTCCCCATTGCGCGCCCGGTTCGGTATATCCAGCAGGTTTGACTACTATCCACCCGAACTGCT
TGAGCGTATTATTTTAAGGGCATCAGGCATTCTTGGAATCGGCGTGACGACGGAAGCTGCAGGTGAAATTGCCGGCAGAT
CAAGAGGTACGCCCCGTATTGCCAATCGCCTTTTACGACGAGCGAGGGATTTTGCCCAGGTTGCTGATTCTTTTGTCATC
AATCACGATATTGCCATGACAACCCTTGCCTCTCTTGAAATTGATGAAGAAGGTCTTGATGATATGGATAAAAAAATAAT
GGATACCATTGTCAACAAGTTTAACGGAGGGCCGGTTGGTGTTGCTTCTCTTGCTGTCTCTGTAGGAGAAGAACAGGATA
CCATTGAGGAGGTCTATGAGCCCTATTTGATACAGGCAGGGTATCTTGCCAGAACTCCGAGGGGCAGGGTCGCTACGAGG
CTTGCTCTCAAGAGATTTTCTTCAGGATCCGGCATTAACAGCAGCGAAGGGCCTTTGTTCGATGCAGCGCCTGCACGATA
A

Upstream 100 bases:

>100_bases
ATCTCTTATTGTCCTCGGAAACCTTGTTGCTGATGTGTTCTATGCTGTTGCGGATCCGAGAATCAAGCTTTAAATTATTC
CGAGAGGAACTCTTTGGCCA

Downstream 100 bases:

>100_bases
GATCTTTTTTCGAAAAGAACGCTTTGCGAAAAGCGTAAGGCCAGTCTTTGCGTATTCTGGTATGGTCGTTGCGATTTGTA
TTTTGCTGCTGTTTTTTTCG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKIELLNTPADALEIRYEEQIRPLKMDDFTGQQRLTDNLRVFISAAKIRGDALDHVLLSGPPGLGKTTLANIIASEMGGN
IKVTSGPMLDKAGNLAGLLTSLRKGDVLFIDEIHRLPAAVEEYLYSAMEDFRIDIMLDSGPSARAVQLRIEPFTLVGATT
RSGLLTSPLRARFGISSRFDYYPPELLERIILRASGILGIGVTTEAAGEIAGRSRGTPRIANRLLRRARDFAQVADSFVI
NHDIAMTTLASLEIDEEGLDDMDKKIMDTIVNKFNGGPVGVASLAVSVGEEQDTIEEVYEPYLIQAGYLARTPRGRVATR
LALKRFSSGSGINSSEGPLFDAAPAR

Sequences:

>Translated_346_residues
MKIELLNTPADALEIRYEEQIRPLKMDDFTGQQRLTDNLRVFISAAKIRGDALDHVLLSGPPGLGKTTLANIIASEMGGN
IKVTSGPMLDKAGNLAGLLTSLRKGDVLFIDEIHRLPAAVEEYLYSAMEDFRIDIMLDSGPSARAVQLRIEPFTLVGATT
RSGLLTSPLRARFGISSRFDYYPPELLERIILRASGILGIGVTTEAAGEIAGRSRGTPRIANRLLRRARDFAQVADSFVI
NHDIAMTTLASLEIDEEGLDDMDKKIMDTIVNKFNGGPVGVASLAVSVGEEQDTIEEVYEPYLIQAGYLARTPRGRVATR
LALKRFSSGSGINSSEGPLFDAAPAR
>Mature_346_residues
MKIELLNTPADALEIRYEEQIRPLKMDDFTGQQRLTDNLRVFISAAKIRGDALDHVLLSGPPGLGKTTLANIIASEMGGN
IKVTSGPMLDKAGNLAGLLTSLRKGDVLFIDEIHRLPAAVEEYLYSAMEDFRIDIMLDSGPSARAVQLRIEPFTLVGATT
RSGLLTSPLRARFGISSRFDYYPPELLERIILRASGILGIGVTTEAAGEIAGRSRGTPRIANRLLRRARDFAQVADSFVI
NHDIAMTTLASLEIDEEGLDDMDKKIMDTIVNKFNGGPVGVASLAVSVGEEQDTIEEVYEPYLIQAGYLARTPRGRVATR
LALKRFSSGSGINSSEGPLFDAAPAR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=318, Percent_Identity=55.0314465408805, Blast_Score=357, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_CHLPD (A1BDZ8)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_911049.1
- ProteinModelPortal:   A1BDZ8
- SMR:   A1BDZ8
- STRING:   A1BDZ8
- GeneID:   4569164
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0569
- NMPDR:   fig|290317.7.peg.597
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37589; Mature: 37589

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIELLNTPADALEIRYEEQIRPLKMDDFTGQQRLTDNLRVFISAAKIRGDALDHVLLSG
CEEEEECCCHHHHHEEEHHHCCCCCCCCCCCHHHHHHHHHEEEEHHHHCCHHHHHHEECC
PPGLGKTTLANIIASEMGGNIKVTSGPMLDKAGNLAGLLTSLRKGDVLFIDEIHRLPAAV
CCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHH
EEYLYSAMEDFRIDIMLDSGPSARAVQLRIEPFTLVGATTRSGLLTSPLRARFGISSRFD
HHHHHHHHHHCEEEEEECCCCCCEEEEEEECCEEEEECCCCCCCCCCCHHHHCCCCCCCC
YYPPELLERIILRASGILGIGVTTEAAGEIAGRSRGTPRIANRLLRRARDFAQVADSFVI
CCCHHHHHHHHHHHCCEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NHDIAMTTLASLEIDEEGLDDMDKKIMDTIVNKFNGGPVGVASLAVSVGEEQDTIEEVYE
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHC
PYLIQAGYLARTPRGRVATRLALKRFSSGSGINSSEGPLFDAAPAR
CCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIELLNTPADALEIRYEEQIRPLKMDDFTGQQRLTDNLRVFISAAKIRGDALDHVLLSG
CEEEEECCCHHHHHEEEHHHCCCCCCCCCCCHHHHHHHHHEEEEHHHHCCHHHHHHEECC
PPGLGKTTLANIIASEMGGNIKVTSGPMLDKAGNLAGLLTSLRKGDVLFIDEIHRLPAAV
CCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHH
EEYLYSAMEDFRIDIMLDSGPSARAVQLRIEPFTLVGATTRSGLLTSPLRARFGISSRFD
HHHHHHHHHHCEEEEEECCCCCCEEEEEEECCEEEEECCCCCCCCCCCHHHHCCCCCCCC
YYPPELLERIILRASGILGIGVTTEAAGEIAGRSRGTPRIANRLLRRARDFAQVADSFVI
CCCHHHHHHHHHHHCCEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NHDIAMTTLASLEIDEEGLDDMDKKIMDTIVNKFNGGPVGVASLAVSVGEEQDTIEEVYE
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHC
PYLIQAGYLARTPRGRVATRLALKRFSSGSGINSSEGPLFDAAPAR
CCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA