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The map label for this gene is sglT [H]

Identifier: 119356053

GI number: 119356053

Start: 230985

End: 232397

Strand: Direct

Name: sglT [H]

Synonym: Cpha266_0206

Alternate gene names: 119356053

Gene position: 230985-232397 (Clockwise)

Preceding gene: 119356052

Following gene: 119356054

Centisome position: 7.37

GC content: 49.68

Gene sequence:

>1413_bases
ATGCAGGCACTTGACATTGCTATCATCGTATTCTTTCTTGCAGGAAGCATCCTGCTCGGTCTATGGCAGGGCAAAAGCAA
CAAAAACACAGGAGATTACTTCCTCGGAGGCCACAAGTTTCCATGGATCGTAGCGATGCTCTCTATCGTCGCGACAGAAA
CATCGGTACTGACCTTCGTCAGCGTTCCGGGGCTTGCCTACCGTGGGGACTGGACATTCCTGCAGCTTCCGCTAGGCTAC
ATTCTGGGAAGAATACTTGTCAGTATCCTTCTACTGCCGGTTTATTTCAAAAACGGCGTAACTTCAATCTATGAAGTGAT
CGGCTCACGATTTGGCACCGGCATGCAGAAACTTGCGTCGATCGTATTTCTGGTCACCAGAATTCTTGGCGATGGAGTGC
GCTTCCTCGCAACGGGAGTAGTCGTTCAGGTCGTAACCGGTTGGTCTCTCCCTGTCTCGGTCATGATAATAGGTGTCGTC
ACACTGGTCTATACCATAACCGGAGGGCTGAAAACAGTCGTATGGCTCGACAGTATCCAGTTCGGTCTTTATCTCCTCGG
TGGAATTATCACTATTGCCTTTATCCTGCTGCATCTGGAAAGCAGCCCACAGGAAACGTTCGCAGCGCTTGCCGACGCAG
GAAAACTTGCAGTGCTGAACACCGGAGGAAACATTCTCTTTAATCCCATGACCTTTGGCAGCGCCTTTACCGGCGGAATA
TTCCTTTCGCTTGCATCTCACGGCATCGATTACATGATGGTTCAGCGCGTTCTTGGCTGCAGAGATCTCGGGTCAGCGCG
CAAAGCCCTTATCGGGAGCGGATTTTTCGTTTTTTTTCAGTTCATGATCTTTCTGCTCGCCGGTTCGCTCATGTACCTAT
TCATGCAGGGCTCGGTAACGGAAAAAGACCGTGAGTTCGCATCGTTCATCGTCAACTACCTCCCTTCGGGATTGAAGGGG
TTACTGCTTGCCGGAATTCTCTCCGCCGCCATGTCAACCATAGCATCGTCGATCAATTCTCTTGCTGCGTCCACCGTTAC
CGATCTGCTCGGAGGACGGGTATCGCTCAATTTCTCGAAACTCATCAGCGCTGGATGGGCAGTGGTACTCATTGGCATCG
CGCTTATTTTCGATGAAAGCGACAAAGCAATCATCATGGTTGGCCTTGAAATAGCATCATTCACCTATGGCGGACTGCTT
GGGCTCTTCCTGCTGTCAAAAACAACACAAAAATATCATCCCGCAAGCCTTGCCATAGGCCTGCTTGCGAGCATGGGGAT
TGTATTCGTGCTCAAGCTCTATGGCATTGCCTGGACATGGTATATTCTCGTTTCCGTTTCTGTAAATATCATGATAACTA
TCCTGGTCAACACTATGCTCAGGAGTATAATGTCGAAAGGTGAACAATCGTAA

Upstream 100 bases:

>100_bases
GCCATCAATCATCAGCTCCTGGCAACAGGATGAAACCGCTTTTCTTGTGACGAAAGAACAGTACCATCTTTATCGATAAC
GGATATAACTGAAATTATCC

Downstream 100 bases:

>100_bases
AAGAAACACTCTCAGGTTTGTTCTAATCACATGAAAAATGCTTTTGCAGTCAAGCCATATTTTACTACATTTATCTATGA
ATTTCTTTTAATGCAAAAAG

Product: Na+/solute symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MQALDIAIIVFFLAGSILLGLWQGKSNKNTGDYFLGGHKFPWIVAMLSIVATETSVLTFVSVPGLAYRGDWTFLQLPLGY
ILGRILVSILLLPVYFKNGVTSIYEVIGSRFGTGMQKLASIVFLVTRILGDGVRFLATGVVVQVVTGWSLPVSVMIIGVV
TLVYTITGGLKTVVWLDSIQFGLYLLGGIITIAFILLHLESSPQETFAALADAGKLAVLNTGGNILFNPMTFGSAFTGGI
FLSLASHGIDYMMVQRVLGCRDLGSARKALIGSGFFVFFQFMIFLLAGSLMYLFMQGSVTEKDREFASFIVNYLPSGLKG
LLLAGILSAAMSTIASSINSLAASTVTDLLGGRVSLNFSKLISAGWAVVLIGIALIFDESDKAIIMVGLEIASFTYGGLL
GLFLLSKTTQKYHPASLAIGLLASMGIVFVLKLYGIAWTWYILVSVSVNIMITILVNTMLRSIMSKGEQS

Sequences:

>Translated_470_residues
MQALDIAIIVFFLAGSILLGLWQGKSNKNTGDYFLGGHKFPWIVAMLSIVATETSVLTFVSVPGLAYRGDWTFLQLPLGY
ILGRILVSILLLPVYFKNGVTSIYEVIGSRFGTGMQKLASIVFLVTRILGDGVRFLATGVVVQVVTGWSLPVSVMIIGVV
TLVYTITGGLKTVVWLDSIQFGLYLLGGIITIAFILLHLESSPQETFAALADAGKLAVLNTGGNILFNPMTFGSAFTGGI
FLSLASHGIDYMMVQRVLGCRDLGSARKALIGSGFFVFFQFMIFLLAGSLMYLFMQGSVTEKDREFASFIVNYLPSGLKG
LLLAGILSAAMSTIASSINSLAASTVTDLLGGRVSLNFSKLISAGWAVVLIGIALIFDESDKAIIMVGLEIASFTYGGLL
GLFLLSKTTQKYHPASLAIGLLASMGIVFVLKLYGIAWTWYILVSVSVNIMITILVNTMLRSIMSKGEQS
>Mature_470_residues
MQALDIAIIVFFLAGSILLGLWQGKSNKNTGDYFLGGHKFPWIVAMLSIVATETSVLTFVSVPGLAYRGDWTFLQLPLGY
ILGRILVSILLLPVYFKNGVTSIYEVIGSRFGTGMQKLASIVFLVTRILGDGVRFLATGVVVQVVTGWSLPVSVMIIGVV
TLVYTITGGLKTVVWLDSIQFGLYLLGGIITIAFILLHLESSPQETFAALADAGKLAVLNTGGNILFNPMTFGSAFTGGI
FLSLASHGIDYMMVQRVLGCRDLGSARKALIGSGFFVFFQFMIFLLAGSLMYLFMQGSVTEKDREFASFIVNYLPSGLKG
LLLAGILSAAMSTIASSINSLAASTVTDLLGGRVSLNFSKLISAGWAVVLIGIALIFDESDKAIIMVGLEIASFTYGGLL
GLFLLSKTTQKYHPASLAIGLLASMGIVFVLKLYGIAWTWYILVSVSVNIMITILVNTMLRSIMSKGEQS

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI4507035, Length=394, Percent_Identity=28.1725888324873, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI256985183, Length=432, Percent_Identity=26.8518518518519, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI157671931, Length=396, Percent_Identity=26.7676767676768, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI167466278, Length=400, Percent_Identity=28.25, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI4507031, Length=426, Percent_Identity=23.0046948356808, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI14140236, Length=420, Percent_Identity=24.5238095238095, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI110835708, Length=467, Percent_Identity=23.1263383297645, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI17941285, Length=377, Percent_Identity=23.8726790450928, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI206597483, Length=385, Percent_Identity=23.8961038961039, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4507033, Length=393, Percent_Identity=23.9185750636132, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI109659836, Length=385, Percent_Identity=23.1168831168831, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI109659839, Length=401, Percent_Identity=21.9451371571072, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI206597487, Length=410, Percent_Identity=22.6829268292683, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790113, Length=344, Percent_Identity=22.9651162790698, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533094, Length=343, Percent_Identity=28.2798833819242, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI115533096, Length=221, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28573698, Length=465, Percent_Identity=25.3763440860215, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24651741, Length=449, Percent_Identity=24.7216035634744, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24651739, Length=422, Percent_Identity=24.6445497630332, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281362054, Length=433, Percent_Identity=25.8660508083141, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281362052, Length=433, Percent_Identity=25.8660508083141, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281362050, Length=433, Percent_Identity=25.8660508083141, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24648056, Length=433, Percent_Identity=25.8660508083141, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21356827, Length=433, Percent_Identity=25.8660508083141, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24641117, Length=454, Percent_Identity=25.1101321585903, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI28574994, Length=442, Percent_Identity=24.2081447963801, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24645928, Length=381, Percent_Identity=26.7716535433071, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281362918, Length=389, Percent_Identity=23.6503856041131, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24650192, Length=410, Percent_Identity=26.3414634146341, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI221459584, Length=397, Percent_Identity=27.7078085642317, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640370, Length=399, Percent_Identity=26.3157894736842, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI161076631, Length=422, Percent_Identity=23.696682464455, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI281364280, Length=374, Percent_Identity=25.9358288770053, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221459588, Length=404, Percent_Identity=26.2376237623762, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19920916, Length=418, Percent_Identity=24.4019138755981, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221379702, Length=403, Percent_Identity=22.8287841191067, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 50419; Mature: 50419

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALDIAIIVFFLAGSILLGLWQGKSNKNTGDYFLGGHKFPWIVAMLSIVATETSVLTFV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHEEE
SVPGLAYRGDWTFLQLPLGYILGRILVSILLLPVYFKNGVTSIYEVIGSRFGTGMQKLAS
ECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHH
IVFLVTRILGDGVRFLATGVVVQVVTGWSLPVSVMIIGVVTLVYTITGGLKTVVWLDSIQ
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FGLYLLGGIITIAFILLHLESSPQETFAALADAGKLAVLNTGGNILFNPMTFGSAFTGGI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCEEECCCCCCCHHHHHH
FLSLASHGIDYMMVQRVLGCRDLGSARKALIGSGFFVFFQFMIFLLAGSLMYLFMQGSVT
HHHHHHCCHHHHHHHHHHCHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
EKDREFASFIVNYLPSGLKGLLLAGILSAAMSTIASSINSLAASTVTDLLGGRVSLNFSK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHH
LISAGWAVVLIGIALIFDESDKAIIMVGLEIASFTYGGLLGLFLLSKTTQKYHPASLAIG
HHHCCHHHHHHHHHHHEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LLASMGIVFVLKLYGIAWTWYILVSVSVNIMITILVNTMLRSIMSKGEQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQALDIAIIVFFLAGSILLGLWQGKSNKNTGDYFLGGHKFPWIVAMLSIVATETSVLTFV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHEEE
SVPGLAYRGDWTFLQLPLGYILGRILVSILLLPVYFKNGVTSIYEVIGSRFGTGMQKLAS
ECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHH
IVFLVTRILGDGVRFLATGVVVQVVTGWSLPVSVMIIGVVTLVYTITGGLKTVVWLDSIQ
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FGLYLLGGIITIAFILLHLESSPQETFAALADAGKLAVLNTGGNILFNPMTFGSAFTGGI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCEEECCCCCCCHHHHHH
FLSLASHGIDYMMVQRVLGCRDLGSARKALIGSGFFVFFQFMIFLLAGSLMYLFMQGSVT
HHHHHHCCHHHHHHHHHHCHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
EKDREFASFIVNYLPSGLKGLLLAGILSAAMSTIASSINSLAASTVTDLLGGRVSLNFSK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHH
LISAGWAVVLIGIALIFDESDKAIIMVGLEIASFTYGGLLGLFLLSKTTQKYHPASLAIG
HHHCCHHHHHHHHHHHEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LLASMGIVFVLKLYGIAWTWYILVSVSVNIMITILVNTMLRSIMSKGEQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]