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The map label for this gene is mpg1 [H]

Identifier: 119356051

GI number: 119356051

Start: 228839

End: 229774

Strand: Direct

Name: mpg1 [H]

Synonym: Cpha266_0204

Alternate gene names: 119356051

Gene position: 228839-229774 (Clockwise)

Preceding gene: 119356050

Following gene: 119356052

Centisome position: 7.3

GC content: 51.07

Gene sequence:

>936_bases
ATGAAAGCATTCGTTCTTGCCGCAGGCTTCGGAACAAGGCTCAGGCCATTTACCCATCGTATTCCCAAACCTCTCATACC
GGTACTGAATCTGCCCGCTCTGCTCTATACCTTCGCTCTGCTTAAGGATGCCGGTATTACCGATATCATCTGCAACATCC
ATCATCATGCAGATGATGTCCGCGAGAGCGTGGCATCTTTTGGCATTGAAGGGCTTGCGATTTCGTTTTCTGAAGAGACA
ACAATCCTTGGTACGGGGGGAGGTCTCAAGAAATGCGAACAACTGTTCGACGACGAAGATTTTCTTCTCATTAACAGCGA
TATCATAACCGATATAGATTTTTCGGCCTTCATTCGACACCATAAGCTATCGGGTCTGCCCGGCACACTTGCACTCTATG
AAACGCCTGAGGCCATGGCTATCGGCTGCATAGGCATCGAAAACGGTCAGGTGAAGGATTTCCGCAACATGCGGAATACC
GGCCTGAAATCATCGTTGATCTATACTGGAACAGCCCTTTTGAGTCCCAAAATATTCCGCTATCTGAACGAAGATTTTTC
AAGCATTGTCGATACAGGATTTACCGGACTGATCGATCACGGCGGACTCGGCGCTTTCAGACATTCCGGTTCATGGATGG
ATATCGGCACTCCGGAAGATTACCTCGATGCAAACAACGGCAAGGGCATGCTTCCTGAACGACTTACCCGCAGAGTTCGC
GATGCCATCGGCATCGAACCGCACCGTATTGCAGCGGACGCATGGATAGCCTCCGGGGCAAGAGTCATACGCTCGGTTAT
CGGCTCCCGCTGCATGGTCAGCAGGAACGCTGTTGTTGAAAACTCGGTACTTCTGCCCGGCGCCGTAGTCGCTGAAGGGG
AATGTCTCCTCAACAGTATCCGCGACAGAGAGAACACTCTGCAAACGATCCCGTGA

Upstream 100 bases:

>100_bases
CACCAGCACTGCGTTATCTTCCTGACTATATTTCCGGAAGAAACGAACTGAAGAAAGCCGGCAGACTCCTCCAGCCGGTC
ATTGAACAACGACACGAGAG

Downstream 100 bases:

>100_bases
ACCAACCAATAACCCAGCCACCGCCATGGTAAAAACAGGTCTTGATATATTTCTCGAAAACATCGACGGTTACCGGAACA
GGACTATCGGCATGATTGTA

Product: nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKAFVLAAGFGTRLRPFTHRIPKPLIPVLNLPALLYTFALLKDAGITDIICNIHHHADDVRESVASFGIEGLAISFSEET
TILGTGGGLKKCEQLFDDEDFLLINSDIITDIDFSAFIRHHKLSGLPGTLALYETPEAMAIGCIGIENGQVKDFRNMRNT
GLKSSLIYTGTALLSPKIFRYLNEDFSSIVDTGFTGLIDHGGLGAFRHSGSWMDIGTPEDYLDANNGKGMLPERLTRRVR
DAIGIEPHRIAADAWIASGARVIRSVIGSRCMVSRNAVVENSVLLPGAVVAEGECLLNSIRDRENTLQTIP

Sequences:

>Translated_311_residues
MKAFVLAAGFGTRLRPFTHRIPKPLIPVLNLPALLYTFALLKDAGITDIICNIHHHADDVRESVASFGIEGLAISFSEET
TILGTGGGLKKCEQLFDDEDFLLINSDIITDIDFSAFIRHHKLSGLPGTLALYETPEAMAIGCIGIENGQVKDFRNMRNT
GLKSSLIYTGTALLSPKIFRYLNEDFSSIVDTGFTGLIDHGGLGAFRHSGSWMDIGTPEDYLDANNGKGMLPERLTRRVR
DAIGIEPHRIAADAWIASGARVIRSVIGSRCMVSRNAVVENSVLLPGAVVAEGECLLNSIRDRENTLQTIP
>Mature_311_residues
MKAFVLAAGFGTRLRPFTHRIPKPLIPVLNLPALLYTFALLKDAGITDIICNIHHHADDVRESVASFGIEGLAISFSEET
TILGTGGGLKKCEQLFDDEDFLLINSDIITDIDFSAFIRHHKLSGLPGTLALYETPEAMAIGCIGIENGQVKDFRNMRNT
GLKSSLIYTGTALLSPKIFRYLNEDFSSIVDTGFTGLIDHGGLGAFRHSGSWMDIGTPEDYLDANNGKGMLPERLTRRVR
DAIGIEPHRIAADAWIASGARVIRSVIGSRCMVSRNAVVENSVLLPGAVVAEGECLLNSIRDRENTLQTIP

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=302, Percent_Identity=30.794701986755, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI11761619, Length=302, Percent_Identity=30.794701986755, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI31881779, Length=347, Percent_Identity=24.7838616714697, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI45447090, Length=347, Percent_Identity=24.7838616714697, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI133931050, Length=347, Percent_Identity=26.5129682997118, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17509979, Length=325, Percent_Identity=26.4615384615385, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17509981, Length=312, Percent_Identity=25.6410256410256, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320148, Length=309, Percent_Identity=28.4789644012945, Blast_Score=129, Evalue=7e-31,
Organism=Drosophila melanogaster, GI21355443, Length=299, Percent_Identity=28.7625418060201, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24644084, Length=299, Percent_Identity=28.7625418060201, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 33864; Mature: 33864

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFVLAAGFGTRLRPFTHRIPKPLIPVLNLPALLYTFALLKDAGITDIICNIHHHADDV
CCEEEEECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RESVASFGIEGLAISFSEETTILGTGGGLKKCEQLFDDEDFLLINSDIITDIDFSAFIRH
HHHHHHCCCCCEEEEECCCEEEEECCCCHHHHHHHHCCCCEEEECCCHHCCCCHHHHHHH
HKLSGLPGTLALYETPEAMAIGCIGIENGQVKDFRNMRNTGLKSSLIYTGTALLSPKIFR
HHCCCCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHHCCCCCHHEEECHHHHHHHHHH
YLNEDFSSIVDTGFTGLIDHGGLGAFRHSGSWMDIGTPEDYLDANNGKGMLPERLTRRVR
HHHHHHHHHHHCCCHHHHCCCCCCCEECCCCEEECCCCHHHHCCCCCCCCCHHHHHHHHH
DAIGIEPHRIAADAWIASGARVIRSVIGSRCMVSRNAVVENSVLLPGAVVAEGECLLNSI
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHEECCCCHHCCCEECCCHHEECCHHHHHHH
RDRENTLQTIP
HHHHHHHCCCC
>Mature Secondary Structure
MKAFVLAAGFGTRLRPFTHRIPKPLIPVLNLPALLYTFALLKDAGITDIICNIHHHADDV
CCEEEEECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RESVASFGIEGLAISFSEETTILGTGGGLKKCEQLFDDEDFLLINSDIITDIDFSAFIRH
HHHHHHCCCCCEEEEECCCEEEEECCCCHHHHHHHHCCCCEEEECCCHHCCCCHHHHHHH
HKLSGLPGTLALYETPEAMAIGCIGIENGQVKDFRNMRNTGLKSSLIYTGTALLSPKIFR
HHCCCCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHHCCCCCHHEEECHHHHHHHHHH
YLNEDFSSIVDTGFTGLIDHGGLGAFRHSGSWMDIGTPEDYLDANNGKGMLPERLTRRVR
HHHHHHHHHHHCCCHHHHCCCCCCCEECCCCEEECCCCHHHHCCCCCCCCCHHHHHHHHH
DAIGIEPHRIAADAWIASGARVIRSVIGSRCMVSRNAVVENSVLLPGAVVAEGECLLNSI
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHEECCCCHHCCCEECCCHHEECCHHHHHHH
RDRENTLQTIP
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]