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The map label for this gene is yuxG [H]

Identifier: 119356042

GI number: 119356042

Start: 219381

End: 221498

Strand: Reverse

Name: yuxG [H]

Synonym: Cpha266_0195

Alternate gene names: 119356042

Gene position: 221498-219381 (Counterclockwise)

Preceding gene: 119356043

Following gene: 119356041

Centisome position: 7.07

GC content: 60.62

Gene sequence:

>2118_bases
ATGCAAAACCTCTGGAATGATGCCGAACTTCAGCGCTCCGTAAATGGGCAGCGCAGCGCCAACGATATTCCTGTTGAACT
TGCCGAGCTCGTGTACGCTTCACGTCTGCTCGGCAGCGAGAGTACGCTGGTGATGCACGGCGGCGGCAACACCTCGGTCA
AAAGCGAGCTGCACGATATCATCGGCTACAGGGTCAATGTCATTTTCATCAAGGGGAGCGGCGTCAATCTGGCGGGTGTG
GATGCGCACGATTTTATGCCGGTACGGATCGAGCCGCTACAGAAGCTGCAGCATCTCTACGCTACCGGCGGGCGCAGCAG
CGAGGAGGATATACAGCAGTTCTCAACGCAACGGTTCAAAAACTTCCTCTATCTGAACCTGTTCTACCTGACCGAGCACA
TGGTGAACCATTCGCTTTCACCCTCGATCGAAACCCTGCTGCACGCGTTTCTGCCCCACCGGTTCATTTTCCATACGCAC
TCCACGGCGCTTTTGACGCTCAGCAACCAGCCTGACGGCCAGGATCTCTGCCGGGAGGTGCTCGGAGAATCGTTCGGCAT
GGTGCCCTATATCAAGCCGGGTCTCGGGCTCGCCCGTTCGGCCGCTACGGCCTACGAATCGGCTCCCTCCATCAGGGGCC
TTGTGCTGCAGAAGCACGGCCTCGTCACCTTTGCCGATACTCCGGATGAAGCGTACCATTGCATGATCGAAAGCGCAAAC
CTTCTGGAAGAGCGCATTACCCGAGCCGGCCGGAAGGTGTTCCCTTCGGTTTCGCTTCCCGCCGGGATCGCATCCCTCGA
GGATACCGCGCCGGTTATCAGAGGGGCTGTCGTTGAAGAGATCATGCCCGGAAGCCGCGATTACCGTCAGTTCGTGCTCG
AATTCCGTACTTCACCCGATATTCTTGCCTATGTCAACAGCGATTCTCTTTCCGATGTAAGCCAGAGGGGCGCCATGACC
CCGGATTTCATTATCCGCACCAAAAACCGGCCGCTGATCGTTCCGACTCCCGATGCCTCTGACCTCGACGCGTTCAAAAC
GGCGGTTCATGAAGCGGTGGAGCGGTATGACGCGGAGTACAGGGCTTATTTCCAGCGCCGGCGGCAGGCTGCGGGAATCG
AGGTTTCCATGCTCGATCCGCTGCCCAGGGTGGTGCTTGTGCCCGGTCTCGGTCTGTTCGGTCTCGGCCGGACCGCCCGG
GAGGCTGCGGTCAACGCCGATATCGCCGAAAGCACGGCATCGGCCATTCTCGACGCGGAATCGGTTGGACGCTTCGAGTC
GATTACCGAACAGGAGGTTTTCGATATCGAGTACTGGGAGATGGAGCAGGCCAAGATGACGAAGGTCCGCCACGACGTGT
TTGCCGGCAAGGTTGCCCTGGTAACCGGTGCGGCAAGCGGCATCGGGCTGGCGACGGCAAGGGCGTTCCGTCAGCGCGGC
GCAGAGCTGGTCATTCTGGACCTGAACCCTGAGGCGCTTCAGCAGGCGGCCGAAGAGCTCGGCGGCGGAGTGCTTCCGAT
TGCGTGCGACGTTACCGACCGCGCTGCCGTCAGGCGGGCTTTCGACAAGGTGTGCCGCCGTTACGGAGGGCTGGATATCT
TGGTCTCGAATGTAGGCGTCGCCCTGCAGGGCCGCATAGGCGACGTTCCGGACGAGGTGCTTCGCCGGAGCTTCGAACTC
AACTTTTTTTCGCATCAGTCCATAGCCCAGGAGGCGGTCAGGATCATGCGACTGCAGGGAACCGGGGGCGTCCTGCTCTT
CAACGTTTCCAAGCAGGCGGTCAATCCGGGTCCCGATTTCGGGCCGTACGGCCTGCCCAAGGCGGCGACCATGTTTCTCG
TGCGCCAGTATGCGCTCGATCACGGACGCGACGGCATCAGGGCAAACGGCATCAATGCCGACAGGATCCGCACCGGCCTT
CTGACCGACGAAATGATCAAAATCCGTTCGACAGCACGGGGGCTGAACGAGCGGGAGTATATGGCCGGCAACCTCCTGCA
GGTCGAGGTCACGGCCGAGGATGTCGCCGAGGCATTCGTGCACCAGGCGCTCGAAACGAAGACGACCGGCTCGATCGTCA
CGGTTGACGGCGGCAACATTGCCGCCGCACTGCGCTGA

Upstream 100 bases:

>100_bases
CGTTTACCATGCTTTTTCGATGGTAAACGGCAATTATTGTTATTAGTTATTTTCTTGCTCTGCATTATGTGAGAATTCCG
TTTAAAATAAAGGGTTTTTT

Downstream 100 bases:

>100_bases
GAGTGAAATTCCTGAAAAACGGATTGCAGATTGTAACTGTCAAACTTTAACCGAAAGAGGAGAATACTATCATGGCTGAA
TATGACAAGGACAAGCAGGC

Product: short chain dehydrogenase

Products: 3alpha12alpha-dihydroxy-oxobeta-cholanate; NADH [C]

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 705; Mature: 705

Protein sequence:

>705_residues
MQNLWNDAELQRSVNGQRSANDIPVELAELVYASRLLGSESTLVMHGGGNTSVKSELHDIIGYRVNVIFIKGSGVNLAGV
DAHDFMPVRIEPLQKLQHLYATGGRSSEEDIQQFSTQRFKNFLYLNLFYLTEHMVNHSLSPSIETLLHAFLPHRFIFHTH
STALLTLSNQPDGQDLCREVLGESFGMVPYIKPGLGLARSAATAYESAPSIRGLVLQKHGLVTFADTPDEAYHCMIESAN
LLEERITRAGRKVFPSVSLPAGIASLEDTAPVIRGAVVEEIMPGSRDYRQFVLEFRTSPDILAYVNSDSLSDVSQRGAMT
PDFIIRTKNRPLIVPTPDASDLDAFKTAVHEAVERYDAEYRAYFQRRRQAAGIEVSMLDPLPRVVLVPGLGLFGLGRTAR
EAAVNADIAESTASAILDAESVGRFESITEQEVFDIEYWEMEQAKMTKVRHDVFAGKVALVTGAASGIGLATARAFRQRG
AELVILDLNPEALQQAAEELGGGVLPIACDVTDRAAVRRAFDKVCRRYGGLDILVSNVGVALQGRIGDVPDEVLRRSFEL
NFFSHQSIAQEAVRIMRLQGTGGVLLFNVSKQAVNPGPDFGPYGLPKAATMFLVRQYALDHGRDGIRANGINADRIRTGL
LTDEMIKIRSTARGLNEREYMAGNLLQVEVTAEDVAEAFVHQALETKTTGSIVTVDGGNIAAALR

Sequences:

>Translated_705_residues
MQNLWNDAELQRSVNGQRSANDIPVELAELVYASRLLGSESTLVMHGGGNTSVKSELHDIIGYRVNVIFIKGSGVNLAGV
DAHDFMPVRIEPLQKLQHLYATGGRSSEEDIQQFSTQRFKNFLYLNLFYLTEHMVNHSLSPSIETLLHAFLPHRFIFHTH
STALLTLSNQPDGQDLCREVLGESFGMVPYIKPGLGLARSAATAYESAPSIRGLVLQKHGLVTFADTPDEAYHCMIESAN
LLEERITRAGRKVFPSVSLPAGIASLEDTAPVIRGAVVEEIMPGSRDYRQFVLEFRTSPDILAYVNSDSLSDVSQRGAMT
PDFIIRTKNRPLIVPTPDASDLDAFKTAVHEAVERYDAEYRAYFQRRRQAAGIEVSMLDPLPRVVLVPGLGLFGLGRTAR
EAAVNADIAESTASAILDAESVGRFESITEQEVFDIEYWEMEQAKMTKVRHDVFAGKVALVTGAASGIGLATARAFRQRG
AELVILDLNPEALQQAAEELGGGVLPIACDVTDRAAVRRAFDKVCRRYGGLDILVSNVGVALQGRIGDVPDEVLRRSFEL
NFFSHQSIAQEAVRIMRLQGTGGVLLFNVSKQAVNPGPDFGPYGLPKAATMFLVRQYALDHGRDGIRANGINADRIRTGL
LTDEMIKIRSTARGLNEREYMAGNLLQVEVTAEDVAEAFVHQALETKTTGSIVTVDGGNIAAALR
>Mature_705_residues
MQNLWNDAELQRSVNGQRSANDIPVELAELVYASRLLGSESTLVMHGGGNTSVKSELHDIIGYRVNVIFIKGSGVNLAGV
DAHDFMPVRIEPLQKLQHLYATGGRSSEEDIQQFSTQRFKNFLYLNLFYLTEHMVNHSLSPSIETLLHAFLPHRFIFHTH
STALLTLSNQPDGQDLCREVLGESFGMVPYIKPGLGLARSAATAYESAPSIRGLVLQKHGLVTFADTPDEAYHCMIESAN
LLEERITRAGRKVFPSVSLPAGIASLEDTAPVIRGAVVEEIMPGSRDYRQFVLEFRTSPDILAYVNSDSLSDVSQRGAMT
PDFIIRTKNRPLIVPTPDASDLDAFKTAVHEAVERYDAEYRAYFQRRRQAAGIEVSMLDPLPRVVLVPGLGLFGLGRTAR
EAAVNADIAESTASAILDAESVGRFESITEQEVFDIEYWEMEQAKMTKVRHDVFAGKVALVTGAASGIGLATARAFRQRG
AELVILDLNPEALQQAAEELGGGVLPIACDVTDRAAVRRAFDKVCRRYGGLDILVSNVGVALQGRIGDVPDEVLRRSFEL
NFFSHQSIAQEAVRIMRLQGTGGVLLFNVSKQAVNPGPDFGPYGLPKAATMFLVRQYALDHGRDGIRANGINADRIRTGL
LTDEMIKIRSTARGLNEREYMAGNLLQVEVTAEDVAEAFVHQALETKTTGSIVTVDGGNIAAALR

Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]

COG id: COG3347

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=202, Percent_Identity=33.1683168316832, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI126723191, Length=201, Percent_Identity=31.8407960199005, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI40807363, Length=126, Percent_Identity=35.7142857142857, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=32.3383084577114, Blast_Score=77, Evalue=8e-14,
Organism=Homo sapiens, GI310128830, Length=115, Percent_Identity=36.5217391304348, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI310115468, Length=115, Percent_Identity=36.5217391304348, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI7705925, Length=188, Percent_Identity=31.9148936170213, Blast_Score=74, Evalue=7e-13,
Organism=Homo sapiens, GI224922801, Length=177, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI210032110, Length=166, Percent_Identity=27.1084337349398, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=32.8, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082100, Length=187, Percent_Identity=31.5508021390374, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI1789378, Length=214, Percent_Identity=31.3084112149533, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1790717, Length=262, Percent_Identity=26.7175572519084, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1787545, Length=265, Percent_Identity=29.0566037735849, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=28.0155642023346, Blast_Score=63, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=123, Percent_Identity=31.7073170731707, Blast_Score=63, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=200, Percent_Identity=33, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=202, Percent_Identity=33.1683168316832, Blast_Score=86, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=200, Percent_Identity=32.5, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=200, Percent_Identity=34, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=199, Percent_Identity=33.1658291457286, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=222, Percent_Identity=28.8288288288288, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=206, Percent_Identity=32.0388349514563, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=200, Percent_Identity=32, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=28.3088235294118, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=200, Percent_Identity=31.5, Blast_Score=76, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=199, Percent_Identity=27.1356783919598, Blast_Score=73, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=200, Percent_Identity=28, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=202, Percent_Identity=30.6930693069307, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=270, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=198, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24663911, Length=177, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28571387, Length=248, Percent_Identity=26.6129032258064, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21355319, Length=189, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644339, Length=191, Percent_Identity=29.3193717277487, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641232, Length=140, Percent_Identity=32.1428571428571, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571526, Length=268, Percent_Identity=28.7313432835821, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357041, Length=193, Percent_Identity=29.0155440414508, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR013454
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short; PF00596 Aldolase_II [H]

EC number: 1.1.1.159 [C]

Molecular weight: Translated: 77149; Mature: 77149

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNLWNDAELQRSVNGQRSANDIPVELAELVYASRLLGSESTLVMHGGGNTSVKSELHDI
CCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
IGYRVNVIFIKGSGVNLAGVDAHDFMPVRIEPLQKLQHLYATGGRSSEEDIQQFSTQRFK
CCCEEEEEEEECCCCCEECCCCCCCCCEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
NFLYLNLFYLTEHMVNHSLSPSIETLLHAFLPHRFIFHTHSTALLTLSNQPDGQDLCREV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHEEEEECCEEEEEECCCCCHHHHHHHH
LGESFGMVPYIKPGLGLARSAATAYESAPSIRGLVLQKHGLVTFADTPDEAYHCMIESAN
HHCCCCCCCEECCCCCHHHHHHHHHHCCCCHHEEEEEECCEEEEECCCCHHHHHHHHHHH
LLEERITRAGRKVFPSVSLPAGIASLEDTAPVIRGAVVEEIMPGSRDYRQFVLEFRTSPD
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
ILAYVNSDSLSDVSQRGAMTPDFIIRTKNRPLIVPTPDASDLDAFKTAVHEAVERYDAEY
EEEEECCCCHHHHHHCCCCCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHCHHH
RAYFQRRRQAAGIEVSMLDPLPRVVLVPGLGLFGLGRTAREAAVNADIAESTASAILDAE
HHHHHHHHHHCCCEEEECCCCCCEEEECCCCHHCCCCHHHHHHHCCHHHHHHHHHHHCHH
SVGRFESITEQEVFDIEYWEMEQAKMTKVRHDVFAGKVALVTGAASGIGLATARAFRQRG
HHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHCC
AELVILDLNPEALQQAAEELGGGVLPIACDVTDRAAVRRAFDKVCRRYGGLDILVSNVGV
CEEEEEECCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEEECCCE
ALQGRIGDVPDEVLRRSFELNFFSHQSIAQEAVRIMRLQGTGGVLLFNVSKQAVNPGPDF
EEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCEEEEECCHHCCCCCCCC
GPYGLPKAATMFLVRQYALDHGRDGIRANGINADRIRTGLLTDEMIKIRSTARGLNEREY
CCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHCCCHHHHHHHHHHHCCCCCHHH
MAGNLLQVEVTAEDVAEAFVHQALETKTTGSIVTVDGGNIAAALR
HCCCEEEEEECHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEECC
>Mature Secondary Structure
MQNLWNDAELQRSVNGQRSANDIPVELAELVYASRLLGSESTLVMHGGGNTSVKSELHDI
CCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
IGYRVNVIFIKGSGVNLAGVDAHDFMPVRIEPLQKLQHLYATGGRSSEEDIQQFSTQRFK
CCCEEEEEEEECCCCCEECCCCCCCCCEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
NFLYLNLFYLTEHMVNHSLSPSIETLLHAFLPHRFIFHTHSTALLTLSNQPDGQDLCREV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHEEEEECCEEEEEECCCCCHHHHHHHH
LGESFGMVPYIKPGLGLARSAATAYESAPSIRGLVLQKHGLVTFADTPDEAYHCMIESAN
HHCCCCCCCEECCCCCHHHHHHHHHHCCCCHHEEEEEECCEEEEECCCCHHHHHHHHHHH
LLEERITRAGRKVFPSVSLPAGIASLEDTAPVIRGAVVEEIMPGSRDYRQFVLEFRTSPD
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
ILAYVNSDSLSDVSQRGAMTPDFIIRTKNRPLIVPTPDASDLDAFKTAVHEAVERYDAEY
EEEEECCCCHHHHHHCCCCCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHCHHH
RAYFQRRRQAAGIEVSMLDPLPRVVLVPGLGLFGLGRTAREAAVNADIAESTASAILDAE
HHHHHHHHHHCCCEEEECCCCCCEEEECCCCHHCCCCHHHHHHHCCHHHHHHHHHHHCHH
SVGRFESITEQEVFDIEYWEMEQAKMTKVRHDVFAGKVALVTGAASGIGLATARAFRQRG
HHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHCC
AELVILDLNPEALQQAAEELGGGVLPIACDVTDRAAVRRAFDKVCRRYGGLDILVSNVGV
CEEEEEECCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEEECCCE
ALQGRIGDVPDEVLRRSFELNFFSHQSIAQEAVRIMRLQGTGGVLLFNVSKQAVNPGPDF
EEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCEEEEECCHHCCCCCCCC
GPYGLPKAATMFLVRQYALDHGRDGIRANGINADRIRTGLLTDEMIKIRSTARGLNEREY
CCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHCCCHHHHHHHHHHHCCCCCHHH
MAGNLLQVEVTAEDVAEAFVHQALETKTTGSIVTVDGGNIAAALR
HCCCEEEEEECHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: 2-Mercaptoethanol; Dithiothreitol; NAD+; NADH [C]

Metal ions: CaCl2; KCl; MnCl2; NaCl [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.8 {cholic} 0.24 {taurochenodeoxycholic} 0.085 {glycochenodeoxycholic} 1 {glycocholic} 0.06 {chenodeoxycholic} [C]

Substrates: @ALPH01.txt*3alpha7alpha12alpha-Trihydroxybeta-cholanate!; NAD [C]

Specific reaction: @ALPH01.txt*3alpha7alpha12alpha-Trihydroxybeta-cholanate! + NAD+ = 3alpha12alpha-dihydroxy-oxobeta-cholanate + NADH [C]

General reaction: Redox reaction [C]

Inhibitor: Ascorbicacid; BaCl2; CoCl2; CuCl2; EDTA; FeCl3; HgCl2; MgCl2; NH4Cl; Potassiumoxalate; Sodiumcitrate; Sodiumlaurylsulfate; Sodiumperchlorate; Sodiumperiodate; Sodiumpersulfate; TritonX-100; Tween; ZnCl2 [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 8188684 [H]