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The map label for this gene is ytfL [C]

Identifier: 119355948

GI number: 119355948

Start: 114296

End: 115678

Strand: Reverse

Name: ytfL [C]

Synonym: Cpha266_0098

Alternate gene names: 119355948

Gene position: 115678-114296 (Counterclockwise)

Preceding gene: 119355949

Following gene: 119355946

Centisome position: 3.69

GC content: 53.94

Gene sequence:

>1383_bases
ATGAAACGCCACACTGAACATGAGTTCAGGGAACCCGACAATTTATCTATGGAAATCCTTTTTCTTCTTTTTCTCATTAT
TATCAACGGCATTTTTGCCATGTCGGAGATCGCTCTGATTACGACAAAGCGTACCCGTTTGACAAAACTTGCTGAAAGCG
GCGATAAATCTGCGGCTGCCGCCCTGAAACTCGGCCATGAACCGACAACCTTTCTCTCCACCATCCAGATCGGGATCACC
TCGATAGGCATCCTCAATGGTATTGTCGGCCAAGGAGCTCTTGCCGAACCCTTTGCCGTATGGCTCGAATCGCTCGGCAT
GGCTCATGACGCCAGTCACATTGGGGCAACCGCCGTTGTCGTCATCTCCATTACCTACATCACCATCGTGGTCGGAGAGC
TTGTCCCCAAACGCCTCGGACAGTTCAATCCCGAAGGGGCCGCTCGACTCTTTGCCCGCCCCATGCTGATGCTTGCCACC
ATAGCCAGACCGTTTGTCCGTCTGCTTTCAGTCTCGACCGATACCTTGCTGAGGCTTATGGGAAAAAGCCCGCAGGCCAT
GCCAAGCGTGACCGAAGAGGAGATTCACGCCATGCTTGAAGAGGGATCTGAAGCCGGAGTCATCGAGCAGCAGGAACACG
ACATGGTTCGCAACGTCTTCAGACTCGACGACCGTCAGCTCGGATCGCTTATGGTACCGAGGGCGGATATTGTCTATCTC
GATATAACCCGACCGCTTGAAGAAAATATCCTGCGAGTGACGGAATCGGAACACTCCCGCTTTCCGGTCTGTAATGGAGG
AATGCAATCGCTTCTCGGAGTGGTCAATGCCAAACAGTTGCTCTCCCAGACACTGAAAGGAGGCCTCAACGACTTCACCT
CGCAACTGCAACCCTATGTCTATGTTCCCGAAACCCTGACCGGCATGGAGCTGCTCGATCACTTCAGAACATCCGGCACC
CAGATGGTCTTTGTTGTCGACGAATATGGCGAAGTACAGGGTCTGGTAACCCTGCAGGACATGCTCGAAGCGGTAACCGG
CGAGTTCGTTCCCCGCAATCTTGAGGATTCCTGGGCGGTTGAACGGGAAGACGGCTCATGGCTGCTTGACGGACTGATCC
CCGTGCCTGAGCTCAAGGACAAACTCGAACTGCTCAGCGTGCCCGAAGAGGATAAGGGGCTCTATCATACGCTCAGCGGC
CTGCTGATGTGGAGCCTCGGACGGATGCCGCAAACCGGCGATGTTGCAACCTGGGAAAACTGGCGTCTTGAAATCGTTGA
CCTTGACGGAAACAGGATTGATAAAGTACTTGCATCGAAAATCCCGCCTCCCGATACCAACGGTCTCAAACAGAACGGCT
CGGCGGCGGGGGAAAAAAACTGA

Upstream 100 bases:

>100_bases
GAGCCGTGGAAAGGGCGAAAAAAAAAGTGCGGAAAAAATATTCCTGAAAAAAGTTACCTTTACCCTGAAACAACAGGGTT
TCCCGTGCGGCTCCTTATAA

Downstream 100 bases:

>100_bases
TCCCGTCAGTTCAACGATACCGTTTTCTGATTTCAAGCTTTTCAATACGCGAATAGAGCGTTTTAGGATGCATCCCGAGC
TTTTCAGCCGCTCCTCCCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MKRHTEHEFREPDNLSMEILFLLFLIIINGIFAMSEIALITTKRTRLTKLAESGDKSAAAALKLGHEPTTFLSTIQIGIT
SIGILNGIVGQGALAEPFAVWLESLGMAHDASHIGATAVVVISITYITIVVGELVPKRLGQFNPEGAARLFARPMLMLAT
IARPFVRLLSVSTDTLLRLMGKSPQAMPSVTEEEIHAMLEEGSEAGVIEQQEHDMVRNVFRLDDRQLGSLMVPRADIVYL
DITRPLEENILRVTESEHSRFPVCNGGMQSLLGVVNAKQLLSQTLKGGLNDFTSQLQPYVYVPETLTGMELLDHFRTSGT
QMVFVVDEYGEVQGLVTLQDMLEAVTGEFVPRNLEDSWAVEREDGSWLLDGLIPVPELKDKLELLSVPEEDKGLYHTLSG
LLMWSLGRMPQTGDVATWENWRLEIVDLDGNRIDKVLASKIPPPDTNGLKQNGSAAGEKN

Sequences:

>Translated_460_residues
MKRHTEHEFREPDNLSMEILFLLFLIIINGIFAMSEIALITTKRTRLTKLAESGDKSAAAALKLGHEPTTFLSTIQIGIT
SIGILNGIVGQGALAEPFAVWLESLGMAHDASHIGATAVVVISITYITIVVGELVPKRLGQFNPEGAARLFARPMLMLAT
IARPFVRLLSVSTDTLLRLMGKSPQAMPSVTEEEIHAMLEEGSEAGVIEQQEHDMVRNVFRLDDRQLGSLMVPRADIVYL
DITRPLEENILRVTESEHSRFPVCNGGMQSLLGVVNAKQLLSQTLKGGLNDFTSQLQPYVYVPETLTGMELLDHFRTSGT
QMVFVVDEYGEVQGLVTLQDMLEAVTGEFVPRNLEDSWAVEREDGSWLLDGLIPVPELKDKLELLSVPEEDKGLYHTLSG
LLMWSLGRMPQTGDVATWENWRLEIVDLDGNRIDKVLASKIPPPDTNGLKQNGSAAGEKN
>Mature_460_residues
MKRHTEHEFREPDNLSMEILFLLFLIIINGIFAMSEIALITTKRTRLTKLAESGDKSAAAALKLGHEPTTFLSTIQIGIT
SIGILNGIVGQGALAEPFAVWLESLGMAHDASHIGATAVVVISITYITIVVGELVPKRLGQFNPEGAARLFARPMLMLAT
IARPFVRLLSVSTDTLLRLMGKSPQAMPSVTEEEIHAMLEEGSEAGVIEQQEHDMVRNVFRLDDRQLGSLMVPRADIVYL
DITRPLEENILRVTESEHSRFPVCNGGMQSLLGVVNAKQLLSQTLKGGLNDFTSQLQPYVYVPETLTGMELLDHFRTSGT
QMVFVVDEYGEVQGLVTLQDMLEAVTGEFVPRNLEDSWAVEREDGSWLLDGLIPVPELKDKLELLSVPEEDKGLYHTLSG
LLMWSLGRMPQTGDVATWENWRLEIVDLDGNRIDKVLASKIPPPDTNGLKQNGSAAGEKN

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=365, Percent_Identity=25.4794520547945, Blast_Score=147, Evalue=2e-35,
Organism=Escherichia coli, GI1790664, Length=433, Percent_Identity=30.9468822170901, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI87082033, Length=335, Percent_Identity=31.6417910447761, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI145693175, Length=420, Percent_Identity=26.4285714285714, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1788119, Length=335, Percent_Identity=31.6417910447761, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786879, Length=256, Percent_Identity=27.34375, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50748; Mature: 50748

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRHTEHEFREPDNLSMEILFLLFLIIINGIFAMSEIALITTKRTRLTKLAESGDKSAAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHCCCHHHHH
ALKLGHEPTTFLSTIQIGITSIGILNGIVGQGALAEPFAVWLESLGMAHDASHIGATAVV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHCHHHHH
VISITYITIVVGELVPKRLGQFNPEGAARLFARPMLMLATIARPFVRLLSVSTDTLLRLM
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GKSPQAMPSVTEEEIHAMLEEGSEAGVIEQQEHDMVRNVFRLDDRQLGSLMVPRADIVYL
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHCCEECCCCCEEEE
DITRPLEENILRVTESEHSRFPVCNGGMQSLLGVVNAKQLLSQTLKGGLNDFTSQLQPYV
EECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEE
YVPETLTGMELLDHFRTSGTQMVFVVDEYGEVQGLVTLQDMLEAVTGEFVPRNLEDSWAV
ECCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
EREDGSWLLDGLIPVPELKDKLELLSVPEEDKGLYHTLSGLLMWSLGRMPQTGDVATWEN
ECCCCCEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
WRLEIVDLDGNRIDKVLASKIPPPDTNGLKQNGSAAGEKN
CEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRHTEHEFREPDNLSMEILFLLFLIIINGIFAMSEIALITTKRTRLTKLAESGDKSAAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHCCCHHHHH
ALKLGHEPTTFLSTIQIGITSIGILNGIVGQGALAEPFAVWLESLGMAHDASHIGATAVV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHCHHHHH
VISITYITIVVGELVPKRLGQFNPEGAARLFARPMLMLATIARPFVRLLSVSTDTLLRLM
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GKSPQAMPSVTEEEIHAMLEEGSEAGVIEQQEHDMVRNVFRLDDRQLGSLMVPRADIVYL
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHCCEECCCCCEEEE
DITRPLEENILRVTESEHSRFPVCNGGMQSLLGVVNAKQLLSQTLKGGLNDFTSQLQPYV
EECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEE
YVPETLTGMELLDHFRTSGTQMVFVVDEYGEVQGLVTLQDMLEAVTGEFVPRNLEDSWAV
ECCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
EREDGSWLLDGLIPVPELKDKLELLSVPEEDKGLYHTLSGLLMWSLGRMPQTGDVATWEN
ECCCCCEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
WRLEIVDLDGNRIDKVLASKIPPPDTNGLKQNGSAAGEKN
CEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]