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The map label for this gene is glyQS [H]

Identifier: 119355895

GI number: 119355895

Start: 46993

End: 48462

Strand: Reverse

Name: glyQS [H]

Synonym: Cpha266_0045

Alternate gene names: 119355895

Gene position: 48462-46993 (Counterclockwise)

Preceding gene: 119355896

Following gene: 119355894

Centisome position: 1.55

GC content: 51.22

Gene sequence:

>1470_bases
ATGAGCAATACTGATTCGAAACGGGTGCAGAACGTCAATCTGCCGCCCGAAAAGGTTATGCATAAACTGGTTTCGCTTGC
CAAGAGACGCGGGTTTATTTTCCCGTCATCCGAAATCTATGAAGGCCTCTCTTCGTGCTTTGACTATGGGCCCCTGGGCA
GCGAGATGAAAAAAAACATCAAAGATCTCTGGTGGAACGCAATGACCCGACGTCACCAGAACATCGTCGGCATTGATGCC
TCGATCATGATGAATCCAAGGGTCTGGGAAGCCTCGGGTCATGTGGCAAGCTTCAACGATCCGATGATCGATGACAAAGC
GACCAAACGGCGTTATCGTGCCGACCATCTGATCGAGAATCATATCGAAAAATTACGTCGCGACGGAAAGGATGATACGG
CATTAAAGGTTCAGACTGCCTATGAACAGGCCTCCACGGCAGCGGATCTGAACAGGGCGCTCTACGATATCATCATAGCC
GAAGGAATCAAAGCCCAGGACACAGGATCAGGGGAGTGGACGGAGGTTCGTCAGTTCAACTTGATGTTCCAGTGCGGCAT
GGGTGCGCTTGCCGATAAAGCAAGCATTGTTTATCTCCGCCCCGAAACCGCTCAGGGTATTTTTGTTAACTTTCATAACG
TACGCGAATCGTCGCGCATGAAGGTGCCGTTCGGCATTGCGCAGATCGGCAAAGCGTTTCGCAACGAGATTGTCAAGGGA
AATTTCATCTTCCGTATGGTGGAGTTCGAGCAGATGGAGATGCAATATTTCGTTAAACCCGGCACCCAGGCCGAAGCTTT
CGAAGCATGGAGAGAGGAGCGTTTCAACTGGTACACCAGCGCACTTGGCATCAACAGGGATAAATTGCACTGGTACAAGC
ATGACAAGCTCGCTCACTATGCCGATCTTGCCTACGACATCAAGTTCGAGTTTCCATTCGGGATAGAGGAGATCGAGGGA
ATTCATTCAAGAACCGATTTCGATCTCAAACAGCATCAGGAATACTCCGGTAAAAACATGGAGTATATCGACCAGCTCAC
CAACGAGCGCTACATCCCTTACGTTGTCGAAACCTCAGCCGGCTGCGACAGGCTCTTTCTTGCTCTGCTCTCTGATGCAT
ACAGCGAAGACGTGGTAGATGGAGAACCGAGAATATCGCTCCGCTTTTCGCCTAAAGTCGCGCCCGTAAAAGCGGCGGTA
CTCCCGCTTCTGAAAAAGGGGGAGATGGCGGAAAAAGCGGCAAGAATTGCTGACGATCTTCGACAACTCTATATGATTCA
GCAAGACGATGCGGGCTCCATAGGCAAGCGATATCGCCGTCAGGACGAGATCGGCACGCCATTCTGCCTTACTATTGACC
ACGAGACGCTGGAAAACGATACCCTTACGATCCGCCACAGGGATACCGCAAGTCAGGAGCGAATCAGCGCCTCATCGATC
CGGGAATTCCTCGCAGCAGGGATGGTATGA

Upstream 100 bases:

>100_bases
GGGCTTAACCAGTGATTATCCCCCCTGGTTTCTTATATTCTATGTTTTATCTATCGAAACGGAAATACCCCGGGATATTT
TACAACCATCTGAACAAACG

Downstream 100 bases:

>100_bases
GCTGCCGCGTTTTTTTAAAACTTTTCGACTATGAGAAACCATGCGCTTTGATGTTGCGGTAATAGGTGGAGGGCCTTCAG
GTGCTGTCGCGGCCGCGGAA

Product: glycyl-tRNA synthetase

Products: NA

Alternate protein names: Glycine--tRNA ligase; GlyRS [H]

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MSNTDSKRVQNVNLPPEKVMHKLVSLAKRRGFIFPSSEIYEGLSSCFDYGPLGSEMKKNIKDLWWNAMTRRHQNIVGIDA
SIMMNPRVWEASGHVASFNDPMIDDKATKRRYRADHLIENHIEKLRRDGKDDTALKVQTAYEQASTAADLNRALYDIIIA
EGIKAQDTGSGEWTEVRQFNLMFQCGMGALADKASIVYLRPETAQGIFVNFHNVRESSRMKVPFGIAQIGKAFRNEIVKG
NFIFRMVEFEQMEMQYFVKPGTQAEAFEAWREERFNWYTSALGINRDKLHWYKHDKLAHYADLAYDIKFEFPFGIEEIEG
IHSRTDFDLKQHQEYSGKNMEYIDQLTNERYIPYVVETSAGCDRLFLALLSDAYSEDVVDGEPRISLRFSPKVAPVKAAV
LPLLKKGEMAEKAARIADDLRQLYMIQQDDAGSIGKRYRRQDEIGTPFCLTIDHETLENDTLTIRHRDTASQERISASSI
REFLAAGMV

Sequences:

>Translated_489_residues
MSNTDSKRVQNVNLPPEKVMHKLVSLAKRRGFIFPSSEIYEGLSSCFDYGPLGSEMKKNIKDLWWNAMTRRHQNIVGIDA
SIMMNPRVWEASGHVASFNDPMIDDKATKRRYRADHLIENHIEKLRRDGKDDTALKVQTAYEQASTAADLNRALYDIIIA
EGIKAQDTGSGEWTEVRQFNLMFQCGMGALADKASIVYLRPETAQGIFVNFHNVRESSRMKVPFGIAQIGKAFRNEIVKG
NFIFRMVEFEQMEMQYFVKPGTQAEAFEAWREERFNWYTSALGINRDKLHWYKHDKLAHYADLAYDIKFEFPFGIEEIEG
IHSRTDFDLKQHQEYSGKNMEYIDQLTNERYIPYVVETSAGCDRLFLALLSDAYSEDVVDGEPRISLRFSPKVAPVKAAV
LPLLKKGEMAEKAARIADDLRQLYMIQQDDAGSIGKRYRRQDEIGTPFCLTIDHETLENDTLTIRHRDTASQERISASSI
REFLAAGMV
>Mature_488_residues
SNTDSKRVQNVNLPPEKVMHKLVSLAKRRGFIFPSSEIYEGLSSCFDYGPLGSEMKKNIKDLWWNAMTRRHQNIVGIDAS
IMMNPRVWEASGHVASFNDPMIDDKATKRRYRADHLIENHIEKLRRDGKDDTALKVQTAYEQASTAADLNRALYDIIIAE
GIKAQDTGSGEWTEVRQFNLMFQCGMGALADKASIVYLRPETAQGIFVNFHNVRESSRMKVPFGIAQIGKAFRNEIVKGN
FIFRMVEFEQMEMQYFVKPGTQAEAFEAWREERFNWYTSALGINRDKLHWYKHDKLAHYADLAYDIKFEFPFGIEEIEGI
HSRTDFDLKQHQEYSGKNMEYIDQLTNERYIPYVVETSAGCDRLFLALLSDAYSEDVVDGEPRISLRFSPKVAPVKAAVL
PLLKKGEMAEKAARIADDLRQLYMIQQDDAGSIGKRYRRQDEIGTPFCLTIDHETLENDTLTIRHRDTASQERISASSIR
EFLAAGMV

Specific function: Catalyzes the attachment of glycine to tRNA(Gly) [H]

COG id: COG0423

COG function: function code J; Glycyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI116805340, Length=358, Percent_Identity=31.2849162011173, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17554996, Length=403, Percent_Identity=31.2655086848635, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI32564541, Length=403, Percent_Identity=31.2655086848635, Blast_Score=167, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6325338, Length=388, Percent_Identity=29.8969072164948, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6319597, Length=408, Percent_Identity=26.4705882352941, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21357965, Length=361, Percent_Identity=32.409972299169, Blast_Score=161, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24664462, Length=361, Percent_Identity=32.409972299169, Blast_Score=161, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR022961
- InterPro:   IPR002315 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 56135; Mature: 56004

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTDSKRVQNVNLPPEKVMHKLVSLAKRRGFIFPSSEIYEGLSSCFDYGPLGSEMKKNI
CCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHH
KDLWWNAMTRRHQNIVGIDASIMMNPRVWEASGHVASFNDPMIDDKATKRRYRADHLIEN
HHHHHHHHHHHCCCEEECCCEEEECCEEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHH
HIEKLRRDGKDDTALKVQTAYEQASTAADLNRALYDIIIAEGIKAQDTGSGEWTEVRQFN
HHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LMFQCGMGALADKASIVYLRPETAQGIFVNFHNVRESSRMKVPFGIAQIGKAFRNEIVKG
HHEECCCCCCCCCCEEEEECCCCCCEEEEEEHHCCCCCCCCCCCCHHHHHHHHHHHHCCC
NFIFRMVEFEQMEMQYFVKPGTQAEAFEAWREERFNWYTSALGINRDKLHWYKHDKLAHY
CEEEEEHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCHHHHH
ADLAYDIKFEFPFGIEEIEGIHSRTDFDLKQHQEYSGKNMEYIDQLTNERYIPYVVETSA
HCEEEEEEEECCCCHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCCEEEECCC
GCDRLFLALLSDAYSEDVVDGEPRISLRFSPKVAPVKAAVLPLLKKGEMAEKAARIADDL
CHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
RQLYMIQQDDAGSIGKRYRRQDEIGTPFCLTIDHETLENDTLTIRHRDTASQERISASSI
HHHHEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHH
REFLAAGMV
HHHHHHCCC
>Mature Secondary Structure 
SNTDSKRVQNVNLPPEKVMHKLVSLAKRRGFIFPSSEIYEGLSSCFDYGPLGSEMKKNI
CCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHH
KDLWWNAMTRRHQNIVGIDASIMMNPRVWEASGHVASFNDPMIDDKATKRRYRADHLIEN
HHHHHHHHHHHCCCEEECCCEEEECCEEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHH
HIEKLRRDGKDDTALKVQTAYEQASTAADLNRALYDIIIAEGIKAQDTGSGEWTEVRQFN
HHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LMFQCGMGALADKASIVYLRPETAQGIFVNFHNVRESSRMKVPFGIAQIGKAFRNEIVKG
HHEECCCCCCCCCCEEEEECCCCCCEEEEEEHHCCCCCCCCCCCCHHHHHHHHHHHHCCC
NFIFRMVEFEQMEMQYFVKPGTQAEAFEAWREERFNWYTSALGINRDKLHWYKHDKLAHY
CEEEEEHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCHHHHH
ADLAYDIKFEFPFGIEEIEGIHSRTDFDLKQHQEYSGKNMEYIDQLTNERYIPYVVETSA
HCEEEEEEEECCCCHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCCEEEECCC
GCDRLFLALLSDAYSEDVVDGEPRISLRFSPKVAPVKAAVLPLLKKGEMAEKAARIADDL
CHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
RQLYMIQQDDAGSIGKRYRRQDEIGTPFCLTIDHETLENDTLTIRHRDTASQERISASSI
HHHHEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHH
REFLAAGMV
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]