Click here to switch to the map view.

The map label for this gene is surA [H]

Identifier: 119355885

GI number: 119355885

Start: 35469

End: 36785

Strand: Direct

Name: surA [H]

Synonym: Cpha266_0035

Alternate gene names: 119355885

Gene position: 35469-36785 (Clockwise)

Preceding gene: 119355884

Following gene: 119355890

Centisome position: 1.13

GC content: 45.63

Gene sequence:

>1317_bases
ATGAAGAAAATGTTGACCGCAGCAGTGTTTGTTATGCTTGTTGCCTTCTCTTTTACCTTGGGCAATCTTCATGCTGATGT
TGCTGATCGTATTGTAGCCGTTGTTGGTAATGAGGTTATACTCAAGTCTGAAATTGATGACCGCGCGTTGATGACCGTCA
TGCAGTATCCCGAGACGCAGAAGGATACTCGTCTGAAAGAAAAAATTCTTGCCGGAATTATTGATCAGAAAGTGATTCTC
GTCAAGGCCAGGATTGACAGTACGCAGGTTGACGAAAGTACACTTGACGCATTGACCAATGAGAGGCTTAAAATGCTGGC
ATCTCGTTTTGCTTCCAAAGAGGCCATGGAGGAGAAGTTCGGAAAATCTATGGGCGTAATCCGCCAGGAAATTCGCAATG
AACTGAAAGACCAGCAGCTTATCGAAACGCTGCGTAAAAAGCAGCTTGCAGGCATTACCGTCACCCATGAGGAAACGGTT
GATTTTTATCGTAATCATAAGCAGCAGTTGCCGCAGGTTTCTGAACTGGTTGGGTTATCGCAGATTCTGAAATATCCTGA
TCTGCCCCAGGGAAGCAAAGATGCCGCTCTGGCTCAGATGAAGATAGTTCAGGCAGAACTGAAGGCCGGAGCGGATTTTG
CCGCAACGGCAAGAAAATACTCTCAGGATCCAGGCTCTGCTAAGCTTGGGGGAGATCTTGGATATGTGCAAAAAGGAGAA
CTTGTTCGTAGCTTTGAGGATGCCGCGTTTTTGCTCAAAGATGGAAAAATATCCGATATTGTCGAAACCCGATACGGCTA
TCACATTATCCAGCGACTTGAAAAAAAACCGAATGCCGTTCATTTGCGACATATACTGATAGCTTATGATCAATCAAAGA
CAGACGAACCGGGTACGGTTCAGCTTCTCAGTCGGATCAAATCGGACGTTCTGGCAGGTCGGGCTACCTTTGCCGATATG
GCTAAAAAATATTCCGACGACCCTGTTTCCGGGAAGCTCGGAGGGGTTATTCTTTCTGGCGGTTCGGGAAAAACATTGCT
TCCGGTAGCTTCGCTTCGTCCTCAAATGATGCAGATTGTAGGAAGTCTGAGAAATATCGGCGATATATCCGATCCTCAAA
AAATCGATTTTCAGAAGGGAAACCTGTTTTACGGAATCTTTCAATTGAATGCGAAAATACCGGTACACCAGCTTAATCTG
GAACAGGACTACGCATCTCTTGAAGAGCTGGCTCTTGAAGCCAAAAAGCAGGAGCGATATAACGAATGGCTCAGCCAGCT
CAAAAAAGAGGTACTTGTCCGAATATCAGACATCTAA

Upstream 100 bases:

>100_bases
TATGTCCTGTAGAGGCTGATGCAAGCCTGGTTTTACCTGCGAATCGTTTTGTGATTCAGGGAACAGAAATCATAACCCAT
TTGACACAGGAGTGACGATA

Downstream 100 bases:

>100_bases
TCGCCGGACATAGCGAGCATTTTTCTCGATGAATTCTCTTCTCGGTTCAACCTTGTCTCCCATCAGCGTCGAAAATATCT
GATCTGCTTCACGGGCATTT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MKKMLTAAVFVMLVAFSFTLGNLHADVADRIVAVVGNEVILKSEIDDRALMTVMQYPETQKDTRLKEKILAGIIDQKVIL
VKARIDSTQVDESTLDALTNERLKMLASRFASKEAMEEKFGKSMGVIRQEIRNELKDQQLIETLRKKQLAGITVTHEETV
DFYRNHKQQLPQVSELVGLSQILKYPDLPQGSKDAALAQMKIVQAELKAGADFAATARKYSQDPGSAKLGGDLGYVQKGE
LVRSFEDAAFLLKDGKISDIVETRYGYHIIQRLEKKPNAVHLRHILIAYDQSKTDEPGTVQLLSRIKSDVLAGRATFADM
AKKYSDDPVSGKLGGVILSGGSGKTLLPVASLRPQMMQIVGSLRNIGDISDPQKIDFQKGNLFYGIFQLNAKIPVHQLNL
EQDYASLEELALEAKKQERYNEWLSQLKKEVLVRISDI

Sequences:

>Translated_438_residues
MKKMLTAAVFVMLVAFSFTLGNLHADVADRIVAVVGNEVILKSEIDDRALMTVMQYPETQKDTRLKEKILAGIIDQKVIL
VKARIDSTQVDESTLDALTNERLKMLASRFASKEAMEEKFGKSMGVIRQEIRNELKDQQLIETLRKKQLAGITVTHEETV
DFYRNHKQQLPQVSELVGLSQILKYPDLPQGSKDAALAQMKIVQAELKAGADFAATARKYSQDPGSAKLGGDLGYVQKGE
LVRSFEDAAFLLKDGKISDIVETRYGYHIIQRLEKKPNAVHLRHILIAYDQSKTDEPGTVQLLSRIKSDVLAGRATFADM
AKKYSDDPVSGKLGGVILSGGSGKTLLPVASLRPQMMQIVGSLRNIGDISDPQKIDFQKGNLFYGIFQLNAKIPVHQLNL
EQDYASLEELALEAKKQERYNEWLSQLKKEVLVRISDI
>Mature_438_residues
MKKMLTAAVFVMLVAFSFTLGNLHADVADRIVAVVGNEVILKSEIDDRALMTVMQYPETQKDTRLKEKILAGIIDQKVIL
VKARIDSTQVDESTLDALTNERLKMLASRFASKEAMEEKFGKSMGVIRQEIRNELKDQQLIETLRKKQLAGITVTHEETV
DFYRNHKQQLPQVSELVGLSQILKYPDLPQGSKDAALAQMKIVQAELKAGADFAATARKYSQDPGSAKLGGDLGYVQKGE
LVRSFEDAAFLLKDGKISDIVETRYGYHIIQRLEKKPNAVHLRHILIAYDQSKTDEPGTVQLLSRIKSDVLAGRATFADM
AKKYSDDPVSGKLGGVILSGGSGKTLLPVASLRPQMMQIVGSLRNIGDISDPQKIDFQKGNLFYGIFQLNAKIPVHQLNL
EQDYASLEELALEAKKQERYNEWLSQLKKEVLVRISDI

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=298, Percent_Identity=28.1879194630872, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 48859; Mature: 48859

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKMLTAAVFVMLVAFSFTLGNLHADVADRIVAVVGNEVILKSEIDDRALMTVMQYPETQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCC
KDTRLKEKILAGIIDQKVILVKARIDSTQVDESTLDALTNERLKMLASRFASKEAMEEKF
HHHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKSMGVIRQEIRNELKDQQLIETLRKKQLAGITVTHEETVDFYRNHKQQLPQVSELVGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHH
QILKYPDLPQGSKDAALAQMKIVQAELKAGADFAATARKYSQDPGSAKLGGDLGYVQKGE
HHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHH
LVRSFEDAAFLLKDGKISDIVETRYGYHIIQRLEKKPNAVHLRHILIAYDQSKTDEPGTV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHEEEEECCCCCCCCHHH
QLLSRIKSDVLAGRATFADMAKKYSDDPVSGKLGGVILSGGSGKTLLPVASLRPQMMQIV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEHHHCCHHHHHHH
GSLRNIGDISDPQKIDFQKGNLFYGIFQLNAKIPVHQLNLEQDYASLEELALEAKKQERY
HHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
NEWLSQLKKEVLVRISDI
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKMLTAAVFVMLVAFSFTLGNLHADVADRIVAVVGNEVILKSEIDDRALMTVMQYPETQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCC
KDTRLKEKILAGIIDQKVILVKARIDSTQVDESTLDALTNERLKMLASRFASKEAMEEKF
HHHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKSMGVIRQEIRNELKDQQLIETLRKKQLAGITVTHEETVDFYRNHKQQLPQVSELVGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHH
QILKYPDLPQGSKDAALAQMKIVQAELKAGADFAATARKYSQDPGSAKLGGDLGYVQKGE
HHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHH
LVRSFEDAAFLLKDGKISDIVETRYGYHIIQRLEKKPNAVHLRHILIAYDQSKTDEPGTV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHEEEEECCCCCCCCHHH
QLLSRIKSDVLAGRATFADMAKKYSDDPVSGKLGGVILSGGSGKTLLPVASLRPQMMQIV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEHHHCCHHHHHHH
GSLRNIGDISDPQKIDFQKGNLFYGIFQLNAKIPVHQLNLEQDYASLEELALEAKKQERY
HHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
NEWLSQLKKEVLVRISDI
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA