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The map label for this gene is surA [H]

Identifier: 118581988

GI number: 118581988

Start: 3968942

End: 3969907

Strand: Direct

Name: surA [H]

Synonym: Ppro_3589

Alternate gene names: 118581988

Gene position: 3968942-3969907 (Clockwise)

Preceding gene: 118581987

Following gene: 118581995

Centisome position: 99.03

GC content: 59.01

Gene sequence:

>966_bases
GTGGTCAAGGTGGAGCAACCCGCAACGGCTCCCCAGCCGATCACCGTACCCGGAAAACTGCTCAACGCCGTTGCCGCCAT
CGTCAACGACGAGATCATCACCCTCTACGAGGTCAATCACGAGGCGCAACCGCTGATCCGTGAAGGCGAGAAAAAGGGGA
GCATGAACGACGAGGAACGGAAACGCATCCGTCGCGCCGCCCTGGACGGTCTGGTGGAAAAGAAACTGGTGGAGCAGAAG
ATCAAGGAGCTGAACATCAAGATCGGCGATGACGAAATCAACCAGGCCATTGATGATGTGAAGCGCCAGAACAACCTGGA
TCAGGAGGGTTTGGTGAAGGCGCTGGCCAGCCAGGGGCTCTCCTATGACCAGTACAAGAGCCAGCTCAGGGAACAGCTGG
AACGGCTCAGGCTGGTCAGCATGGAGGTGCGCTCAAGGATCCAGGTGGGCGAGTCCGAAGTTCGCGCCTATTACAACGAA
AACCTGGCAACCTACAGCGAAGATGAGACCTTCCGCGCCCGGCACATCTTCTTCAAGACCAACGAGAAGGCGCCTGCAGA
GGAGATCAAGCGTACCATGAACACGGCGCTGATGGTGCTGGCCGAGGCCAAGAGCGGCAAGGACTTCGCCGAACTGGCCA
GGACCTATTCCGAGGACCCGGCAGCAAAAAAGGATGGCGGCGACCTGGGCAGCTTCAAGAAGGGGGACATGCAGCCGGAA
CTGGAGCAGGCCATTCTCGGCATGAAGCAGGGCGAAGTCAGTGAACTGGTCTACACCCCCCTGGGATTCCACCTGATCAA
GCTGGAGGCGCGCACCCCCGGCACCCCCAAACCGCTGGAGAGCGTCAAATCCGAGATCGAGGAGACGATTTACCGCAAAA
AATCCGAGGAGCGCTTCAAAAAGTGGGCAACCGAGATGCGCGCCAAGGCGAGCATCGAGCTGAAGGAGTTGCCGGGGTAC
CTGTAA

Upstream 100 bases:

>100_bases
ACGAACCGTTTTTGCCCTGCTGCCCGTCTGCCTCTGCCTGCTGCCCCTTGGTGGATGCGCGAAAAAACAGGCGCTTGTGA
AAGACACACCGCTGTCAACG

Downstream 100 bases:

>100_bases
CAGACACGGCAACTTTTCAGCTGAAACGAAGACAGCCTTTCATCACGGCATATCCTGTGATGAAAGGCTGTCTTTTTATG
CGGCAGGGGGAAACGGGCGT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MVKVEQPATAPQPITVPGKLLNAVAAIVNDEIITLYEVNHEAQPLIREGEKKGSMNDEERKRIRRAALDGLVEKKLVEQK
IKELNIKIGDDEINQAIDDVKRQNNLDQEGLVKALASQGLSYDQYKSQLREQLERLRLVSMEVRSRIQVGESEVRAYYNE
NLATYSEDETFRARHIFFKTNEKAPAEEIKRTMNTALMVLAEAKSGKDFAELARTYSEDPAAKKDGGDLGSFKKGDMQPE
LEQAILGMKQGEVSELVYTPLGFHLIKLEARTPGTPKPLESVKSEIEETIYRKKSEERFKKWATEMRAKASIELKELPGY
L

Sequences:

>Translated_321_residues
MVKVEQPATAPQPITVPGKLLNAVAAIVNDEIITLYEVNHEAQPLIREGEKKGSMNDEERKRIRRAALDGLVEKKLVEQK
IKELNIKIGDDEINQAIDDVKRQNNLDQEGLVKALASQGLSYDQYKSQLREQLERLRLVSMEVRSRIQVGESEVRAYYNE
NLATYSEDETFRARHIFFKTNEKAPAEEIKRTMNTALMVLAEAKSGKDFAELARTYSEDPAAKKDGGDLGSFKKGDMQPE
LEQAILGMKQGEVSELVYTPLGFHLIKLEARTPGTPKPLESVKSEIEETIYRKKSEERFKKWATEMRAKASIELKELPGY
L
>Mature_321_residues
MVKVEQPATAPQPITVPGKLLNAVAAIVNDEIITLYEVNHEAQPLIREGEKKGSMNDEERKRIRRAALDGLVEKKLVEQK
IKELNIKIGDDEINQAIDDVKRQNNLDQEGLVKALASQGLSYDQYKSQLREQLERLRLVSMEVRSRIQVGESEVRAYYNE
NLATYSEDETFRARHIFFKTNEKAPAEEIKRTMNTALMVLAEAKSGKDFAELARTYSEDPAAKKDGGDLGSFKKGDMQPE
LEQAILGMKQGEVSELVYTPLGFHLIKLEARTPGTPKPLESVKSEIEETIYRKKSEERFKKWATEMRAKASIELKELPGY
L

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=206, Percent_Identity=24.7572815533981, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1786645, Length=329, Percent_Identity=22.4924012158055, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 36395; Mature: 36395

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVEQPATAPQPITVPGKLLNAVAAIVNDEIITLYEVNHEAQPLIREGEKKGSMNDEER
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCHHCCCCCHHHH
KRIRRAALDGLVEKKLVEQKIKELNIKIGDDEINQAIDDVKRQNNLDQEGLVKALASQGL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
SYDQYKSQLREQLERLRLVSMEVRSRIQVGESEVRAYYNENLATYSEDETFRARHIFFKT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHEEEEEC
NEKAPAEEIKRTMNTALMVLAEAKSGKDFAELARTYSEDPAAKKDGGDLGSFKKGDMQPE
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
LEQAILGMKQGEVSELVYTPLGFHLIKLEARTPGTPKPLESVKSEIEETIYRKKSEERFK
HHHHHHCCCCCCHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KWATEMRAKASIELKELPGYL
HHHHHHHHHHCCCHHHCCCCC
>Mature Secondary Structure
MVKVEQPATAPQPITVPGKLLNAVAAIVNDEIITLYEVNHEAQPLIREGEKKGSMNDEER
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCHHCCCCCHHHH
KRIRRAALDGLVEKKLVEQKIKELNIKIGDDEINQAIDDVKRQNNLDQEGLVKALASQGL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
SYDQYKSQLREQLERLRLVSMEVRSRIQVGESEVRAYYNENLATYSEDETFRARHIFFKT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHEEEEEC
NEKAPAEEIKRTMNTALMVLAEAKSGKDFAELARTYSEDPAAKKDGGDLGSFKKGDMQPE
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
LEQAILGMKQGEVSELVYTPLGFHLIKLEARTPGTPKPLESVKSEIEETIYRKKSEERFK
HHHHHHCCCCCCHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KWATEMRAKASIELKELPGYL
HHHHHHHHHHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]