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The map label for this gene is nuoN [H]

Identifier: 118581930

GI number: 118581930

Start: 3899615

End: 3901027

Strand: Reverse

Name: nuoN [H]

Synonym: Ppro_3530

Alternate gene names: 118581930

Gene position: 3901027-3899615 (Counterclockwise)

Preceding gene: 118581931

Following gene: 118581929

Centisome position: 97.33

GC content: 62.85

Gene sequence:

>1413_bases
ATGAGCTCGCTTCTGCTTGTTCTTCCGTTGTTAGGCGTAATCGCATCGAACCTCCCCCTGGGGCGTTCCACGAGGCGGGC
CTTGACGCTCTGGCCGCTTCTGCTGGGAGCTGCCCAGGTTGTGGTCTCCCTCTTTCCCCAGGCGGCTGTGTGGGGGATGC
CATCCGCGCTGATCCCCCTGGCGCCGGCCGACGGACTCAGTCAGCTGATGCTTCTGATCATCGGCCTGGTGACCTGTGCC
TCGTCCATCGTCGCCCGGGAGTTGATCACCGATGAGCGGGAGCGGCACAACTTTGCCAGCCTGCTGCTGATCTCCCTGCT
GGGGATGAACGGGGTCGTGCTGGTCAGGGACACCTTCTCGCTCTACGTGTTCATGGAAATCGTCTCGGTTACCTCCTTCG
TCCTGATCGCCTTCCGGCACGAACACGACGCCTTCGAGGGGTCGTTCAAATACATCATCCTCTCGGCCATCGCCACCATA
CTGATGCTGGCCTCCAACGGAATCTTCCTGCTGGTTGGCGGCGGCACGGATTTCCCGCTGGTGGCGGGGGCCATAGCCAG
CCACCACGACAACTTCCTGGTGCAGTTCGCCGTGCTTGCCTTTCTTGCCGGACTGTTCATTAAGGGGGGGCTGGTGCCGT
TCCACGGTTGGCTCCCCGACGCCTACACGTCGGCTTCGGCGCCGGTTTCCATGCTGCTGGCCGGCATCGTGACCAAGGTC
TCCGGCATCTATACCCTGATCCGCCTGGTCAGGGATGTGTTCGGCTTCACTCCCAAGACCGAGCAGATGCTGCTCTTCGT
CGGGGCGCTCTCCATCGTCACCGGTGCCCTGGCTGCCATGGGGCAGCGGGACTTCAAGCGCATGCTCGCCTACTCCAGCA
TCAGCCAGGTCGGCTACATCATACTCAGTCTGGGGGCTGGTTCCGAACTGGGGGTGGCTGGCGCCATCTTCCACCTCTTC
AACCACACCCTCTTCAAGACCCAGCTGTTCATGAACGCCAGCGCGGTTGAGGCCAGTACCGGGATCCGCGACCTGGACCG
TCTGGGTGGTCTTAGCGCCAGGATGCCGATCACCGGTACGACCTCCGTCATCGCCTTCCTGTCGGCGGCCGGAATCCCTC
CCCTGGCCGGCTTCTGGAGCAAGCTGGTGATCGTGGTCGCCCTCTGGAGGGCCGGCCACGGCGGCTACATGGCCGTTGCC
ATCCTGGCTAGCCTGCTGACCCTGGCCTACTTCCTGATCCTGCAGCGCAAGGTCTTCTTCGGGAAACTGGCCCCGGAGTG
GGAGGGCATTAACGAGGCGGGCAGCCTGATTACCGGGCCGAGCATACTCTTCAGCCTGATCATCATCGCGGTGGGGCTGT
TGCTGCCGTTCCTGTTCGATACCATCATCCTGCCGCTGGGGGGGCTTTTATGA

Upstream 100 bases:

>100_bases
GCTGCATAACGGCAGTTACGCCACCTACATGGCCTGGGTGGCCATTGGCCTGATCCTGATGGGGCTGTACCTGAATGTGT
GACACAAGGAGGATAGTGGG

Downstream 100 bases:

>100_bases
ACATCACCACGCTACTGCTCCCCCTGCTGGTCCTGTTCGGTTTCTACACCGTGCTCTCCAAGAGCCTGCTCAGGATGGCC
ATTGGGCTGGCCCTGGTGAG

Product: NADH dehydrogenase (quinone)

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MSSLLLVLPLLGVIASNLPLGRSTRRALTLWPLLLGAAQVVVSLFPQAAVWGMPSALIPLAPADGLSQLMLLIIGLVTCA
SSIVARELITDERERHNFASLLLISLLGMNGVVLVRDTFSLYVFMEIVSVTSFVLIAFRHEHDAFEGSFKYIILSAIATI
LMLASNGIFLLVGGGTDFPLVAGAIASHHDNFLVQFAVLAFLAGLFIKGGLVPFHGWLPDAYTSASAPVSMLLAGIVTKV
SGIYTLIRLVRDVFGFTPKTEQMLLFVGALSIVTGALAAMGQRDFKRMLAYSSISQVGYIILSLGAGSELGVAGAIFHLF
NHTLFKTQLFMNASAVEASTGIRDLDRLGGLSARMPITGTTSVIAFLSAAGIPPLAGFWSKLVIVVALWRAGHGGYMAVA
ILASLLTLAYFLILQRKVFFGKLAPEWEGINEAGSLITGPSILFSLIIIAVGLLLPFLFDTIILPLGGLL

Sequences:

>Translated_470_residues
MSSLLLVLPLLGVIASNLPLGRSTRRALTLWPLLLGAAQVVVSLFPQAAVWGMPSALIPLAPADGLSQLMLLIIGLVTCA
SSIVARELITDERERHNFASLLLISLLGMNGVVLVRDTFSLYVFMEIVSVTSFVLIAFRHEHDAFEGSFKYIILSAIATI
LMLASNGIFLLVGGGTDFPLVAGAIASHHDNFLVQFAVLAFLAGLFIKGGLVPFHGWLPDAYTSASAPVSMLLAGIVTKV
SGIYTLIRLVRDVFGFTPKTEQMLLFVGALSIVTGALAAMGQRDFKRMLAYSSISQVGYIILSLGAGSELGVAGAIFHLF
NHTLFKTQLFMNASAVEASTGIRDLDRLGGLSARMPITGTTSVIAFLSAAGIPPLAGFWSKLVIVVALWRAGHGGYMAVA
ILASLLTLAYFLILQRKVFFGKLAPEWEGINEAGSLITGPSILFSLIIIAVGLLLPFLFDTIILPLGGLL
>Mature_469_residues
SSLLLVLPLLGVIASNLPLGRSTRRALTLWPLLLGAAQVVVSLFPQAAVWGMPSALIPLAPADGLSQLMLLIIGLVTCAS
SIVARELITDERERHNFASLLLISLLGMNGVVLVRDTFSLYVFMEIVSVTSFVLIAFRHEHDAFEGSFKYIILSAIATIL
MLASNGIFLLVGGGTDFPLVAGAIASHHDNFLVQFAVLAFLAGLFIKGGLVPFHGWLPDAYTSASAPVSMLLAGIVTKVS
GIYTLIRLVRDVFGFTPKTEQMLLFVGALSIVTGALAAMGQRDFKRMLAYSSISQVGYIILSLGAGSELGVAGAIFHLFN
HTLFKTQLFMNASAVEASTGIRDLDRLGGLSARMPITGTTSVIAFLSAAGIPPLAGFWSKLVIVVALWRAGHGGYMAVAI
LASLLTLAYFLILQRKVFFGKLAPEWEGINEAGSLITGPSILFSLIIIAVGLLLPFLFDTIILPLGGLL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0651

COG function: function code CP; Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=356, Percent_Identity=27.8089887640449, Blast_Score=103, Evalue=5e-22,
Organism=Escherichia coli, GI1788827, Length=299, Percent_Identity=30.4347826086957, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788831, Length=412, Percent_Identity=27.9126213592233, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1788829, Length=335, Percent_Identity=29.8507462686567, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788613, Length=380, Percent_Identity=27.1052631578947, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788614, Length=367, Percent_Identity=28.3378746594005, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI2367154, Length=215, Percent_Identity=31.6279069767442, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI145693160, Length=388, Percent_Identity=30.4123711340206, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750
- InterPro:   IPR003918 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 49955; Mature: 49824

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLLLVLPLLGVIASNLPLGRSTRRALTLWPLLLGAAQVVVSLFPQAAVWGMPSALIPL
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCC
APADGLSQLMLLIIGLVTCASSIVARELITDERERHNFASLLLISLLGMNGVVLVRDTFS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHH
LYVFMEIVSVTSFVLIAFRHEHDAFEGSFKYIILSAIATILMLASNGIFLLVGGGTDFPL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHH
VAGAIASHHDNFLVQFAVLAFLAGLFIKGGLVPFHGWLPDAYTSASAPVSMLLAGIVTKV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHH
SGIYTLIRLVRDVFGFTPKTEQMLLFVGALSIVTGALAAMGQRDFKRMLAYSSISQVGYI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
ILSLGAGSELGVAGAIFHLFNHTLFKTQLFMNASAVEASTGIRDLDRLGGLSARMPITGT
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHCCCCCCCCCCCH
TSVIAFLSAAGIPPLAGFWSKLVIVVALWRAGHGGYMAVAILASLLTLAYFLILQRKVFF
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GKLAPEWEGINEAGSLITGPSILFSLIIIAVGLLLPFLFDTIILPLGGLL
HCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SSLLLVLPLLGVIASNLPLGRSTRRALTLWPLLLGAAQVVVSLFPQAAVWGMPSALIPL
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCC
APADGLSQLMLLIIGLVTCASSIVARELITDERERHNFASLLLISLLGMNGVVLVRDTFS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHH
LYVFMEIVSVTSFVLIAFRHEHDAFEGSFKYIILSAIATILMLASNGIFLLVGGGTDFPL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHH
VAGAIASHHDNFLVQFAVLAFLAGLFIKGGLVPFHGWLPDAYTSASAPVSMLLAGIVTKV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHH
SGIYTLIRLVRDVFGFTPKTEQMLLFVGALSIVTGALAAMGQRDFKRMLAYSSISQVGYI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
ILSLGAGSELGVAGAIFHLFNHTLFKTQLFMNASAVEASTGIRDLDRLGGLSARMPITGT
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHCCCCCCCCCCCH
TSVIAFLSAAGIPPLAGFWSKLVIVVALWRAGHGGYMAVAILASLLTLAYFLILQRKVFF
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GKLAPEWEGINEAGSLITGPSILFSLIIIAVGLLLPFLFDTIILPLGGLL
HCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA