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The map label for this gene is flhA [H]

Identifier: 118581844

GI number: 118581844

Start: 3803209

End: 3805296

Strand: Direct

Name: flhA [H]

Synonym: Ppro_3444

Alternate gene names: 118581844

Gene position: 3803209-3805296 (Clockwise)

Preceding gene: 118581843

Following gene: 118581845

Centisome position: 94.89

GC content: 55.08

Gene sequence:

>2088_bases
ATGTCAAACAGTACCGTCAAAGCAATAGAATCGAGCGGATTTCGGAAGAATTCCGACATCTATGTGGCTATTGCCCTGAT
CGGTGTTCTGTCGCTGATGATCATCCCGCTCCCCTCCTTTCTGCTGGATGTTTTTCTGGCAGCCAACATCACCATTGCCC
TCTGCATCCTGCTGGTCTGCCTCTATACCACCCACCCGCTGGATTTTTCCGTTTTCCCTTCGGTTCTGCTGGTCACGACA
CTCTTTCGCCTGGCGCTGAATATCGCCTCCACACGCCTGATCCTCTTGCACGGAAGTGAGGGTGTAGAGGCGGCCGGAGC
GGTCATCAAAGCGTTTGGTCAGTTTGTCGTCGGCGGCAACTATGTTGTCGGAGCCGTTATTTTTCTGATTCTGGTAATCA
TAAATTTTGTGGTTATCACGAAGGGTGCCGGACGGGTTGCCGAGGTTACCGCCCGTTTTACGCTGGATGCCATGCCGGGC
AAACAGATGGCCATCGATGCCGATCTTTCGGCCGGCCTGATCACCGAGAAGGACGCCAGGTCACGCCGCCTCAAGATCTC
CCGGGAGGCCGACTTCTACGGCTCCATGGACGGCGCCAGCAAGTTTGTGCGCGGCGACGCCATTGCCGGCATCCTTATCG
TCATGGTCAATATCTTCGGCGGCCTGATCATCGGAATCTTTCAGCAGGGGATGCCGATTCAGGACGCCCTCACCAACTAT
ACCCTGCTGACCATCGGAGAGGGCCTGGTTGCCCAAATTCCCGCATTGATTATCTCCACAGCTGCGGGCATCATCGTAAC
CCGCTCTGCCGACGAGGACAATTTTGGTAATGAAATAACAGGGCAGTTCCTGAACTACCCCAAGGCCTTCTATGTTTCCT
CAGGGGTACTGTTTCTGTTTGCGCTGATTCCCGGTCTGCCTCACTTTGCCTTTTTGCTGCTTTCGGGAACAACGTATCTG
GCCGGCAAAATGGCTCGCGAGAAGACGCAGGTCATAGAGGAGATGGCTGCCTTGCCAGCAACTGCTGAGGGCGAGGAGGG
TATTGATCAGGCATCGGTCATTCGCCCCCTGGACGTGCTGGAACTTGAAGTCGGCTATGGCCTTGTACCCATGGTTGACG
CCTCCCAGGATGGTGAGCTCTTGGAACGCATTCGCTCCATCCGGCGTCAGTACGCCCAGAAACTTGGGTTTGTGGTGCCT
CCCATCCATATCCATGACAATCTGCAGCTCAAGCCGTACGAGTATAACCTGCTTATCCGCGGCGCACGGGTTGGCGGCAG
CGAACTTACCGGCCAGTATCTGGCAATGGACTCCGGGGCTGTTACCGGCTCTATCGAAGGGGTCAGCACAACTGAACCGG
TTTTCGGGCTTCCCTCGGTCTGGATCAGCTCCGAAGGGCGTGATGACGCTCAGTTCAAAGGGTATACCGTTGTTGACAGC
ACAACGGTGGTGGCTACACATATCAGCGAAATCGTGAAACGACATGCCCATGAGCTTGTTGGACGCCAGGAGCTGCAACA
ATTGCTGGACAACCTTGCGGTTACGGCTCCCAAAGTCGTGGACGAACTCATCCCCAACCAGCTTAACCTGGGCACGGTGC
TGCGTGTGGTCAAGAACCTGCTGAAGGAGGGCGTTTCGATCCGAGATATGCGCACCATACTGGAGACACTGGCTGACTAT
GCTACGCTGACCAAGGATCCCGACGTGCTGAGCGAGTTCGTTCGCCAAGGTTTGGGCCGCTTCATTGTCGATCAGTACAA
ACTTGACGACAACATGCTCTGCCTGGTTACCCTGAACAGGGATGTGGAGGACATCATCGCCGAGGCGATCCAACCTTCGG
ATCAGGGTGGTTTTCTGGCCATAGAGCCCAATACCGCCCAGATGATAATAACCGCGATCCGCTCCATGGCGGACCGTTTT
GGTCCCAGCGGTGCACAACCGGTACTGCTGGCTTCCCCGTCCATCCGCAGACACGTAAGAAAACTGATCGAACGCTTTGT
CCCACACATGGCGGTTCTCTCCCACAACGAGATTCCACAGAATATAAAAATTCAATCACTAGGGGTGGTAACCATAAATG
CTGGTTAA

Upstream 100 bases:

>100_bases
TTGGGGAGGCTCCCTGCTACGTTTTACGACAAGGCAAGCGGCACAATTATTGCGTATCAGCTAAAAACATCAGATCAACA
TTTTTGGAATGGGAACATCA

Downstream 100 bases:

>100_bases
GACCTTTCAAGCTCCAAGCATGGCAGAGGCTCTGCGTAAGGTTAAGGCGGAACTTGGCTCCGATGCCATGATTCTTTCGA
CCAAACAGGAAAAGACCGGC

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 695; Mature: 694

Protein sequence:

>695_residues
MSNSTVKAIESSGFRKNSDIYVAIALIGVLSLMIIPLPSFLLDVFLAANITIALCILLVCLYTTHPLDFSVFPSVLLVTT
LFRLALNIASTRLILLHGSEGVEAAGAVIKAFGQFVVGGNYVVGAVIFLILVIINFVVITKGAGRVAEVTARFTLDAMPG
KQMAIDADLSAGLITEKDARSRRLKISREADFYGSMDGASKFVRGDAIAGILIVMVNIFGGLIIGIFQQGMPIQDALTNY
TLLTIGEGLVAQIPALIISTAAGIIVTRSADEDNFGNEITGQFLNYPKAFYVSSGVLFLFALIPGLPHFAFLLLSGTTYL
AGKMAREKTQVIEEMAALPATAEGEEGIDQASVIRPLDVLELEVGYGLVPMVDASQDGELLERIRSIRRQYAQKLGFVVP
PIHIHDNLQLKPYEYNLLIRGARVGGSELTGQYLAMDSGAVTGSIEGVSTTEPVFGLPSVWISSEGRDDAQFKGYTVVDS
TTVVATHISEIVKRHAHELVGRQELQQLLDNLAVTAPKVVDELIPNQLNLGTVLRVVKNLLKEGVSIRDMRTILETLADY
ATLTKDPDVLSEFVRQGLGRFIVDQYKLDDNMLCLVTLNRDVEDIIAEAIQPSDQGGFLAIEPNTAQMIITAIRSMADRF
GPSGAQPVLLASPSIRRHVRKLIERFVPHMAVLSHNEIPQNIKIQSLGVVTINAG

Sequences:

>Translated_695_residues
MSNSTVKAIESSGFRKNSDIYVAIALIGVLSLMIIPLPSFLLDVFLAANITIALCILLVCLYTTHPLDFSVFPSVLLVTT
LFRLALNIASTRLILLHGSEGVEAAGAVIKAFGQFVVGGNYVVGAVIFLILVIINFVVITKGAGRVAEVTARFTLDAMPG
KQMAIDADLSAGLITEKDARSRRLKISREADFYGSMDGASKFVRGDAIAGILIVMVNIFGGLIIGIFQQGMPIQDALTNY
TLLTIGEGLVAQIPALIISTAAGIIVTRSADEDNFGNEITGQFLNYPKAFYVSSGVLFLFALIPGLPHFAFLLLSGTTYL
AGKMAREKTQVIEEMAALPATAEGEEGIDQASVIRPLDVLELEVGYGLVPMVDASQDGELLERIRSIRRQYAQKLGFVVP
PIHIHDNLQLKPYEYNLLIRGARVGGSELTGQYLAMDSGAVTGSIEGVSTTEPVFGLPSVWISSEGRDDAQFKGYTVVDS
TTVVATHISEIVKRHAHELVGRQELQQLLDNLAVTAPKVVDELIPNQLNLGTVLRVVKNLLKEGVSIRDMRTILETLADY
ATLTKDPDVLSEFVRQGLGRFIVDQYKLDDNMLCLVTLNRDVEDIIAEAIQPSDQGGFLAIEPNTAQMIITAIRSMADRF
GPSGAQPVLLASPSIRRHVRKLIERFVPHMAVLSHNEIPQNIKIQSLGVVTINAG
>Mature_694_residues
SNSTVKAIESSGFRKNSDIYVAIALIGVLSLMIIPLPSFLLDVFLAANITIALCILLVCLYTTHPLDFSVFPSVLLVTTL
FRLALNIASTRLILLHGSEGVEAAGAVIKAFGQFVVGGNYVVGAVIFLILVIINFVVITKGAGRVAEVTARFTLDAMPGK
QMAIDADLSAGLITEKDARSRRLKISREADFYGSMDGASKFVRGDAIAGILIVMVNIFGGLIIGIFQQGMPIQDALTNYT
LLTIGEGLVAQIPALIISTAAGIIVTRSADEDNFGNEITGQFLNYPKAFYVSSGVLFLFALIPGLPHFAFLLLSGTTYLA
GKMAREKTQVIEEMAALPATAEGEEGIDQASVIRPLDVLELEVGYGLVPMVDASQDGELLERIRSIRRQYAQKLGFVVPP
IHIHDNLQLKPYEYNLLIRGARVGGSELTGQYLAMDSGAVTGSIEGVSTTEPVFGLPSVWISSEGRDDAQFKGYTVVDST
TVVATHISEIVKRHAHELVGRQELQQLLDNLAVTAPKVVDELIPNQLNLGTVLRVVKNLLKEGVSIRDMRTILETLADYA
TLTKDPDVLSEFVRQGLGRFIVDQYKLDDNMLCLVTLNRDVEDIIAEAIQPSDQGGFLAIEPNTAQMIITAIRSMADRFG
PSGAQPVLLASPSIRRHVRKLIERFVPHMAVLSHNEIPQNIKIQSLGVVTINAG

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=659, Percent_Identity=47.6479514415782, Blast_Score=601, Evalue=1e-173,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75181; Mature: 75049

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSTVKAIESSGFRKNSDIYVAIALIGVLSLMIIPLPSFLLDVFLAANITIALCILLVC
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LYTTHPLDFSVFPSVLLVTTLFRLALNIASTRLILLHGSEGVEAAGAVIKAFGQFVVGGN
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHCCCC
YVVGAVIFLILVIINFVVITKGAGRVAEVTARFTLDAMPGKQMAIDADLSAGLITEKDAR
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCCCCHH
SRRLKISREADFYGSMDGASKFVRGDAIAGILIVMVNIFGGLIIGIFQQGMPIQDALTNY
HHCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
TLLTIGEGLVAQIPALIISTAAGIIVTRSADEDNFGNEITGQFLNYPKAFYVSSGVLFLF
EEEEECCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
ALIPGLPHFAFLLLSGTTYLAGKMAREKTQVIEEMAALPATAEGEEGIDQASVIRPLDVL
HHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHE
ELEVGYGLVPMVDASQDGELLERIRSIRRQYAQKLGFVVPPIHIHDNLQLKPYEYNLLIR
EEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEECCEEEEEEEE
GARVGGSELTGQYLAMDSGAVTGSIEGVSTTEPVFGLPSVWISSEGRDDAQFKGYTVVDS
EEECCCCHHCCCEEEECCCCCEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEEECC
TTVVATHISEIVKRHAHELVGRQELQQLLDNLAVTAPKVVDELIPNQLNLGTVLRVVKNL
CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHH
LKEGVSIRDMRTILETLADYATLTKDPDVLSEFVRQGLGRFIVDQYKLDDNMLCLVTLNR
HHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
DVEDIIAEAIQPSDQGGFLAIEPNTAQMIITAIRSMADRFGPSGAQPVLLASPSIRRHVR
CHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHH
KLIERFVPHMAVLSHNEIPQNIKIQSLGVVTINAG
HHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECC
>Mature Secondary Structure 
SNSTVKAIESSGFRKNSDIYVAIALIGVLSLMIIPLPSFLLDVFLAANITIALCILLVC
CCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LYTTHPLDFSVFPSVLLVTTLFRLALNIASTRLILLHGSEGVEAAGAVIKAFGQFVVGGN
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHCCCC
YVVGAVIFLILVIINFVVITKGAGRVAEVTARFTLDAMPGKQMAIDADLSAGLITEKDAR
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCCCCHH
SRRLKISREADFYGSMDGASKFVRGDAIAGILIVMVNIFGGLIIGIFQQGMPIQDALTNY
HHCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
TLLTIGEGLVAQIPALIISTAAGIIVTRSADEDNFGNEITGQFLNYPKAFYVSSGVLFLF
EEEEECCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
ALIPGLPHFAFLLLSGTTYLAGKMAREKTQVIEEMAALPATAEGEEGIDQASVIRPLDVL
HHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHE
ELEVGYGLVPMVDASQDGELLERIRSIRRQYAQKLGFVVPPIHIHDNLQLKPYEYNLLIR
EEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEECCEEEEEEEE
GARVGGSELTGQYLAMDSGAVTGSIEGVSTTEPVFGLPSVWISSEGRDDAQFKGYTVVDS
EEECCCCHHCCCEEEECCCCCEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEEECC
TTVVATHISEIVKRHAHELVGRQELQQLLDNLAVTAPKVVDELIPNQLNLGTVLRVVKNL
CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHH
LKEGVSIRDMRTILETLADYATLTKDPDVLSEFVRQGLGRFIVDQYKLDDNMLCLVTLNR
HHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
DVEDIIAEAIQPSDQGGFLAIEPNTAQMIITAIRSMADRFGPSGAQPVLLASPSIRRHVR
CHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHH
KLIERFVPHMAVLSHNEIPQNIKIQSLGVVTINAG
HHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]