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The map label for this gene is mraY

Identifier: 118581692

GI number: 118581692

Start: 3628456

End: 3629532

Strand: Reverse

Name: mraY

Synonym: Ppro_3292

Alternate gene names: 118581692

Gene position: 3629532-3628456 (Counterclockwise)

Preceding gene: 118581693

Following gene: 118581691

Centisome position: 90.56

GC content: 61.65

Gene sequence:

>1077_bases
ATGCTGTATCACCTGCTCTATCCATTAGCCGGCGATGTCAAGCTGTTCAACATCTTCAAATACCTGACGTTCCGGACCAT
CTATGCCATGATCACGGCGCTCCTGGTCTGCTTCGTGCTTGGCCCCTGGGTGATCCGCGTGCTGGAGGGACTGCAGGCCC
GCCAGGTGATCCGCACCGATGGCCCGGAATCCCACCTGCAGAAGCAGGGCACCCCGACCATGGGAGGGGTGATGATCCTG
GCGGCCATTGTCATCCCGACCCTGCTGTGGGCCGACCTCTCCAACCAGTACATCTGGACGGTGCTGTTCATAACCATCGG
TTACGGCCTGATCGGCTTTGTTGATGACTACAAGAAGGTGGTGGAGAAGAACCCCAAGGGGCTTTCCCCGCGGCAGAAGA
TGTTCTGGCAGGTCCTGCTGGCCGGCGCGGTGGGGACGTTTCTGTTCCTGAAGCCCGGATTCAACGCCCAGCTCTTTGTC
CCCTTCTTCAAGAACTTCCATCCCGACCTCTGGTTCTGGTACATCCCCTTCGTTACCCTGGTGATCGTGGGGGCCAGCAA
TGCGGTCAACCTGACCGACGGCCTGGACGGCCTGGCCATCGGTCCGGTGGCCATCAATGCCGCCACCTACATGCTCTTCA
GCTATGTCGCCGGTCACGCCACCCTCTCGGCCTACCTGCAGGTCCCGCGGGTGGCGGGCGCGGGAGAGCTGGCCGTTCTC
TGCGGCGCCATGGTGGGGGCCGGGCTCGGTTTCCTCTGGTACAACTCCTATCCCGCCGAGGTCTTCATGGGGGATGTGGG
CTCGCTCTCCCTGGGAGGGACCCTGGGGGCCATCGCGGTGATCACCAAGCAGGAGATCCTGCTGGTCATCGTGGGGGGGA
TCTTCGTGATCGAGGCGCTGTCGGTCATCTTCCAGGTGGGATCGTACAAGTACCGCGGCAAGCGTATCTTCCGCATGGCG
CCGATCCACCACCACTTCGAACTGAAGGGGGTGGCGGAGCCGAAGATCATCGTCCGCTTCTGGATTATTACCATCATCCT
GGCCCTGGTGGCGATCTCCACCCTGAAGATGCGCTAG

Upstream 100 bases:

>100_bases
GGGAGACGGCCCCCTGTGGCTGACCCCACAGCGTAACGGATTTTTGTAAATCTTGGCGCCACAGCCCCCACGGTGGGCTC
GGGCACATACGGAGTAACCC

Downstream 100 bases:

>100_bases
CGCCGGGACGGAAGAGAGGGTTTTTTTAAGCATGGAACTGAACGACAAGAAGGTGCTGGTGGTCGGCCTGGCCAAGACCG
GTGTGGCCTGCGCCCGCTTC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MLYHLLYPLAGDVKLFNIFKYLTFRTIYAMITALLVCFVLGPWVIRVLEGLQARQVIRTDGPESHLQKQGTPTMGGVMIL
AAIVIPTLLWADLSNQYIWTVLFITIGYGLIGFVDDYKKVVEKNPKGLSPRQKMFWQVLLAGAVGTFLFLKPGFNAQLFV
PFFKNFHPDLWFWYIPFVTLVIVGASNAVNLTDGLDGLAIGPVAINAATYMLFSYVAGHATLSAYLQVPRVAGAGELAVL
CGAMVGAGLGFLWYNSYPAEVFMGDVGSLSLGGTLGAIAVITKQEILLVIVGGIFVIEALSVIFQVGSYKYRGKRIFRMA
PIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKMR

Sequences:

>Translated_358_residues
MLYHLLYPLAGDVKLFNIFKYLTFRTIYAMITALLVCFVLGPWVIRVLEGLQARQVIRTDGPESHLQKQGTPTMGGVMIL
AAIVIPTLLWADLSNQYIWTVLFITIGYGLIGFVDDYKKVVEKNPKGLSPRQKMFWQVLLAGAVGTFLFLKPGFNAQLFV
PFFKNFHPDLWFWYIPFVTLVIVGASNAVNLTDGLDGLAIGPVAINAATYMLFSYVAGHATLSAYLQVPRVAGAGELAVL
CGAMVGAGLGFLWYNSYPAEVFMGDVGSLSLGGTLGAIAVITKQEILLVIVGGIFVIEALSVIFQVGSYKYRGKRIFRMA
PIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKMR
>Mature_358_residues
MLYHLLYPLAGDVKLFNIFKYLTFRTIYAMITALLVCFVLGPWVIRVLEGLQARQVIRTDGPESHLQKQGTPTMGGVMIL
AAIVIPTLLWADLSNQYIWTVLFITIGYGLIGFVDDYKKVVEKNPKGLSPRQKMFWQVLLAGAVGTFLFLKPGFNAQLFV
PFFKNFHPDLWFWYIPFVTLVIVGASNAVNLTDGLDGLAIGPVAINAATYMLFSYVAGHATLSAYLQVPRVAGAGELAVL
CGAMVGAGLGFLWYNSYPAEVFMGDVGSLSLGGTLGAIAVITKQEILLVIVGGIFVIEALSVIFQVGSYKYRGKRIFRMA
PIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKMR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=345, Percent_Identity=58.2608695652174, Blast_Score=388, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_PELPD (A1AU64)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902942.1
- STRING:   A1AU64
- GeneID:   4572581
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_3292
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   HATLSAY
- PhylomeDB:   A1AU64
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 39455; Mature: 39455

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x23c2a360)-; HASH(0x27c0d444)-; HASH(0x27c08550)-; HASH(0x27c0888c)-; HASH(0x27c0d5e8)-; HASH(0x279c7380)-; HASH(0x26eccf1c)-; HASH(0x27dd22bc)-; HASH(0x27c08598)-; HASH(0x279c7410)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYHLLYPLAGDVKLFNIFKYLTFRTIYAMITALLVCFVLGPWVIRVLEGLQARQVIRTD
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPESHLQKQGTPTMGGVMILAAIVIPTLLWADLSNQYIWTVLFITIGYGLIGFVDDYKKV
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VEKNPKGLSPRQKMFWQVLLAGAVGTFLFLKPGFNAQLFVPFFKNFHPDLWFWYIPFVTL
HHCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEHHHHCCCCCHHHHHHHHHHH
VIVGASNAVNLTDGLDGLAIGPVAINAATYMLFSYVAGHATLSAYLQVPRVAGAGELAVL
HHHCCCCCEECCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
CGAMVGAGLGFLWYNSYPAEVFMGDVGSLSLGGTLGAIAVITKQEILLVIVGGIFVIEAL
HHHHHHCCHHEEEECCCCHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVIFQVGSYKYRGKRIFRMAPIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKMR
HHHHHHCCCEECCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLYHLLYPLAGDVKLFNIFKYLTFRTIYAMITALLVCFVLGPWVIRVLEGLQARQVIRTD
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPESHLQKQGTPTMGGVMILAAIVIPTLLWADLSNQYIWTVLFITIGYGLIGFVDDYKKV
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VEKNPKGLSPRQKMFWQVLLAGAVGTFLFLKPGFNAQLFVPFFKNFHPDLWFWYIPFVTL
HHCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEHHHHCCCCCHHHHHHHHHHH
VIVGASNAVNLTDGLDGLAIGPVAINAATYMLFSYVAGHATLSAYLQVPRVAGAGELAVL
HHHCCCCCEECCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
CGAMVGAGLGFLWYNSYPAEVFMGDVGSLSLGGTLGAIAVITKQEILLVIVGGIFVIEAL
HHHHHHCCHHEEEECCCCHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVIFQVGSYKYRGKRIFRMAPIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKMR
HHHHHHCCCEECCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA