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The map label for this gene is gph [C]

Identifier: 118581604

GI number: 118581604

Start: 3521083

End: 3521745

Strand: Direct

Name: gph [C]

Synonym: Ppro_3203

Alternate gene names: 118581604

Gene position: 3521083-3521745 (Clockwise)

Preceding gene: 118581595

Following gene: 118581605

Centisome position: 87.85

GC content: 61.69

Gene sequence:

>663_bases
ATGACCATCACCACCATCCTCTTCGACCTCGACGGAACACTCACCGACCCGAAGGCCGGGATAACCGGCTGCATCCGGTT
TTCCCTGGAAAGGCTCGGCCTGACCCCGCCGCACGAAGACCATCTCACCTGGTGCATCGGCCCGCCCCTCAGGGACTCCT
TCTCGCGCCTGATGAACACCAGCGACGACGCGCTCCTTGACCAGGCCCTGGCCCTTTACCGGGAACGTTACTCTCACACC
GGCATGTATGAGAACGAACTCTACCCGGAGAGCATCCCCGCCCTGGAGAAAGCCAGGGACGCGGGACTGCGCATCTTTCT
GGCCACAGCCAAACCCAGGGTCTTCGCCGTGCCGATTCTCGACCACTTCGACCTCACCCAATTCTTCCATGGCGTGCACG
GCAGCGAACTGGACGGCCGCTTCACAAACAAGGGGGAATTGATCGCCCATATCCTCCACACCGAGAATCTAGACCCGAGA
ACGACGCTGATGGTCGGCGACCGCTGCCACGACATATTGGGCGGCAGGGGTAATGGTATACTGACGGCAGCGGTCACCTA
CGGCTATGGCAGCCGCGAAGAGATCGAGGAAGCGGCACCGGACATGGTCTTCGACGCGCTCCCGGAACTGACCGCGTTCC
TGGAATCAAGGGCGCTGCCGTAA

Upstream 100 bases:

>100_bases
AGGAGCATCTGCGGGTCAGACTGGACATTTGGACATTTGGACATTCGCTGACAAATGCCCACCTGCCCCCTTTGTACTCC
CTGGATTTGGAACAGAGAAC

Downstream 100 bases:

>100_bases
CGGTAGCCGGCACAAAACAGATTGCCGTATTCGCGTCAGTTGCCAAAAATGCTCCAACTCCGCTTCGAGTTGTACCTTTC
ATCCGGCTGCGGCTGGTGTC

Product: hydrolase

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MTITTILFDLDGTLTDPKAGITGCIRFSLERLGLTPPHEDHLTWCIGPPLRDSFSRLMNTSDDALLDQALALYRERYSHT
GMYENELYPESIPALEKARDAGLRIFLATAKPRVFAVPILDHFDLTQFFHGVHGSELDGRFTNKGELIAHILHTENLDPR
TTLMVGDRCHDILGGRGNGILTAAVTYGYGSREEIEEAAPDMVFDALPELTAFLESRALP

Sequences:

>Translated_220_residues
MTITTILFDLDGTLTDPKAGITGCIRFSLERLGLTPPHEDHLTWCIGPPLRDSFSRLMNTSDDALLDQALALYRERYSHT
GMYENELYPESIPALEKARDAGLRIFLATAKPRVFAVPILDHFDLTQFFHGVHGSELDGRFTNKGELIAHILHTENLDPR
TTLMVGDRCHDILGGRGNGILTAAVTYGYGSREEIEEAAPDMVFDALPELTAFLESRALP
>Mature_219_residues
TITTILFDLDGTLTDPKAGITGCIRFSLERLGLTPPHEDHLTWCIGPPLRDSFSRLMNTSDDALLDQALALYRERYSHTG
MYENELYPESIPALEKARDAGLRIFLATAKPRVFAVPILDHFDLTQFFHGVHGSELDGRFTNKGELIAHILHTENLDPRT
TLMVGDRCHDILGGRGNGILTAAVTYGYGSREEIEEAAPDMVFDALPELTAFLESRALP

Specific function: Specifically dephosphorylates nucleoside 5'- monophosphates to nucleosides and inorganic phosphate. Displays high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP [H]

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=241, Percent_Identity=24.0663900414938, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 24441; Mature: 24310

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITTILFDLDGTLTDPKAGITGCIRFSLERLGLTPPHEDHLTWCIGPPLRDSFSRLMNT
CEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHCC
SDDALLDQALALYRERYSHTGMYENELYPESIPALEKARDAGLRIFLATAKPRVFAVPIL
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEEEEEECCCCEEEEECC
DHFDLTQFFHGVHGSELDGRFTNKGELIAHILHTENLDPRTTLMVGDRCHDILGGRGNGI
CCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHCCCCCEE
LTAAVTYGYGSREEIEEAAPDMVFDALPELTAFLESRALP
EEEEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TITTILFDLDGTLTDPKAGITGCIRFSLERLGLTPPHEDHLTWCIGPPLRDSFSRLMNT
EEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHCC
SDDALLDQALALYRERYSHTGMYENELYPESIPALEKARDAGLRIFLATAKPRVFAVPIL
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEEEEEECCCCEEEEECC
DHFDLTQFFHGVHGSELDGRFTNKGELIAHILHTENLDPRTTLMVGDRCHDILGGRGNGI
CCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHCCCCCEE
LTAAVTYGYGSREEIEEAAPDMVFDALPELTAFLESRALP
EEEEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]