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The map label for this gene is resE [H]

Identifier: 118581557

GI number: 118581557

Start: 3462440

End: 3464203

Strand: Direct

Name: resE [H]

Synonym: Ppro_3156

Alternate gene names: 118581557

Gene position: 3462440-3464203 (Clockwise)

Preceding gene: 118581556

Following gene: 118581558

Centisome position: 86.39

GC content: 63.66

Gene sequence:

>1764_bases
ATGACATTCCGCTGGAAACTGATGCTTTCCTACCTGCTGCTGATTCTCTTGCTGTCCGGCTCCTATTACCTGAGTTTCGA
TCACAGCGCCCAGAGCTACTTTCTGGACGAGAGCCGCGAGAACCTGATCAGCCAGACCAGACTGGCCAAGCTGCTGGCCG
AGCAGGAGAGGGATACGATGCCGCCCCAACAGCTGGCCGAGAGGATCGGCTCCGCCATCAAGGCCCGCGTCACCCTGATC
GACCGCTCGGGCCTGGTCAGGGGCGACTCCGATGTCAGCAAGGTCGAACTATCCCATCTGGAAAACCACCTCAAACGTCC
GGAAGTCGTCCAGGCCATGCAGGGTGGGATCGGCAGCAGCCTGCGCTATTCCGAGACCCTGAAGACCGACATGCTCTACA
CGGCCCTTGGTTACGAGAGCAACGGCCACTACGGCTTCATCAGACTGTCGCTCCCCCTGGAGCGCCTCTCCAGCGCCACG
GCCGCCCTGCACCGCATGACCGCAGGCTCCGTGGGCATGGCGCTCCTGGCCGCCCTGGCCTTCAGCCTGCTCCTCTCCCG
CGTCACCTCCCGCCCTTTGCGCGAAATGGCGGAGGTGGCCGCCCGCATCGGCAGAGATGGCGAGTACAGCCGCATCCCGG
TCGCCTCCCAGGACGAGATCGGCGCCCTGGCCTCGGTCCTGAACGACATGGCCGAGCGCATCGACGCTCAGATGCACGGG
TTGGACGCGGAAAAGACCCGGCTGGACGCGATCCTGCGCGGCATGGGCGAGGGGGTCATGGTGGCCAGCGCTGACGGTGC
CATCACCCTGGTCAATCCCGCCTTCAGGAAGATGTTCGCCATGACGGACGGGGTAGAGGGGAAAAAGCTGATCGAGGTAT
GCCGCAACCCCGACCTGCAGGCTGCCTTCCATGACCTGGCTCGTTGCGGGGGAGAGCTGAGCCGTGAGATCCGCATCCAG
CCGGGTGATGTCACGCTGCTGACCCATTGGGTGCCCCTGGCCATGGATGGCGCCGGCCAGGGGGTCGTGGCGGTGTTTCA
CGACATTACCGACATGAAACACGTGGAGGAGATGCGCCGCGACTTCGTGGCCAACGTATCCCATGAGCTACGCACCCCGG
TCTCGGTCATCAAGGGATATGCCGAAACCCTCATGCAGAATGACATGCTCGTCTCCGAACCGGAGCACGCCACCCGCTTC
GTGGAGATCATCCGCAGGCATGCCGAACGGTTGACCACCCTGATCAACGACATCCTGACCCTCTCCTGCCTGGAGGCCAG
GAACAGCGCCCTGGAGCTCAACGCCATGGATGTGGGCACGACCATCGCCAAATCCTGCGCCCTGCTCGCCCCCCGGGCAG
CGGAAAAGAAGATTTGCCTCCATAACGAAGTTGGCAACAATCTTCCCCGGACACTTGTCGACCAGGGTCGGCTGGAGCAG
GTGCTGGTGAACCTGATCGACAACGCCGTCAAGTACACTCCCGAGGGGGGCACGATCCGCCTGTTTGCGGAACAGGGAGA
AACGTTCCTCAGAATCTCCGTGCAGGACAGTGGCATCGGCATCCCGCCCAGGGACCTCCCCCGCATCTTCGAGCGCTTCT
ACCGCGTGGATGAGGGACGCAGCCGCGAGCAGGGGGGCACCGGCCTGGGGCTCGCCATCGCCAAGCACATCGTCCAACTC
CACGGCGGCGAACTGACGGTCACGAGCACTCCGGGCAAGGGCTCGACCTTCTCCTTCACCCTGCGCATGGCCACAAACAG
CTGA

Upstream 100 bases:

>100_bases
GATACGCACATCACCCGACTGCGCGGCAAGCTGGGCGCTCCGGGAGAGCAGATCAAGACGGTTCGGGGTTTCGGCTACAA
AATCGAGGAGAACTAGTCCC

Downstream 100 bases:

>100_bases
GTTTTCACACACTGTTTCCCCTTCTGTGACAGAATCGTAACAGTGCCGTGCTAGGGTAACAACCATTGAAAAGCACCACC
CACATCTCAGGAGGATTCCA

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 587; Mature: 586

Protein sequence:

>587_residues
MTFRWKLMLSYLLLILLLSGSYYLSFDHSAQSYFLDESRENLISQTRLAKLLAEQERDTMPPQQLAERIGSAIKARVTLI
DRSGLVRGDSDVSKVELSHLENHLKRPEVVQAMQGGIGSSLRYSETLKTDMLYTALGYESNGHYGFIRLSLPLERLSSAT
AALHRMTAGSVGMALLAALAFSLLLSRVTSRPLREMAEVAARIGRDGEYSRIPVASQDEIGALASVLNDMAERIDAQMHG
LDAEKTRLDAILRGMGEGVMVASADGAITLVNPAFRKMFAMTDGVEGKKLIEVCRNPDLQAAFHDLARCGGELSREIRIQ
PGDVTLLTHWVPLAMDGAGQGVVAVFHDITDMKHVEEMRRDFVANVSHELRTPVSVIKGYAETLMQNDMLVSEPEHATRF
VEIIRRHAERLTTLINDILTLSCLEARNSALELNAMDVGTTIAKSCALLAPRAAEKKICLHNEVGNNLPRTLVDQGRLEQ
VLVNLIDNAVKYTPEGGTIRLFAEQGETFLRISVQDSGIGIPPRDLPRIFERFYRVDEGRSREQGGTGLGLAIAKHIVQL
HGGELTVTSTPGKGSTFSFTLRMATNS

Sequences:

>Translated_587_residues
MTFRWKLMLSYLLLILLLSGSYYLSFDHSAQSYFLDESRENLISQTRLAKLLAEQERDTMPPQQLAERIGSAIKARVTLI
DRSGLVRGDSDVSKVELSHLENHLKRPEVVQAMQGGIGSSLRYSETLKTDMLYTALGYESNGHYGFIRLSLPLERLSSAT
AALHRMTAGSVGMALLAALAFSLLLSRVTSRPLREMAEVAARIGRDGEYSRIPVASQDEIGALASVLNDMAERIDAQMHG
LDAEKTRLDAILRGMGEGVMVASADGAITLVNPAFRKMFAMTDGVEGKKLIEVCRNPDLQAAFHDLARCGGELSREIRIQ
PGDVTLLTHWVPLAMDGAGQGVVAVFHDITDMKHVEEMRRDFVANVSHELRTPVSVIKGYAETLMQNDMLVSEPEHATRF
VEIIRRHAERLTTLINDILTLSCLEARNSALELNAMDVGTTIAKSCALLAPRAAEKKICLHNEVGNNLPRTLVDQGRLEQ
VLVNLIDNAVKYTPEGGTIRLFAEQGETFLRISVQDSGIGIPPRDLPRIFERFYRVDEGRSREQGGTGLGLAIAKHIVQL
HGGELTVTSTPGKGSTFSFTLRMATNS
>Mature_586_residues
TFRWKLMLSYLLLILLLSGSYYLSFDHSAQSYFLDESRENLISQTRLAKLLAEQERDTMPPQQLAERIGSAIKARVTLID
RSGLVRGDSDVSKVELSHLENHLKRPEVVQAMQGGIGSSLRYSETLKTDMLYTALGYESNGHYGFIRLSLPLERLSSATA
ALHRMTAGSVGMALLAALAFSLLLSRVTSRPLREMAEVAARIGRDGEYSRIPVASQDEIGALASVLNDMAERIDAQMHGL
DAEKTRLDAILRGMGEGVMVASADGAITLVNPAFRKMFAMTDGVEGKKLIEVCRNPDLQAAFHDLARCGGELSREIRIQP
GDVTLLTHWVPLAMDGAGQGVVAVFHDITDMKHVEEMRRDFVANVSHELRTPVSVIKGYAETLMQNDMLVSEPEHATRFV
EIIRRHAERLTTLINDILTLSCLEARNSALELNAMDVGTTIAKSCALLAPRAAEKKICLHNEVGNNLPRTLVDQGRLEQV
LVNLIDNAVKYTPEGGTIRLFAEQGETFLRISVQDSGIGIPPRDLPRIFERFYRVDEGRSREQGGTGLGLAIAKHIVQLH
GGELTVTSTPGKGSTFSFTLRMATNS

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=337, Percent_Identity=32.6409495548961, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1789149, Length=235, Percent_Identity=35.7446808510638, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI48994928, Length=255, Percent_Identity=36.078431372549, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI87081816, Length=229, Percent_Identity=36.6812227074236, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI145693157, Length=218, Percent_Identity=33.9449541284404, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1788393, Length=264, Percent_Identity=29.9242424242424, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=33.7606837606838, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI1790861, Length=220, Percent_Identity=35.4545454545455, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1786783, Length=262, Percent_Identity=29.7709923664122, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788713, Length=278, Percent_Identity=28.7769784172662, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=33.1914893617021, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1788549, Length=383, Percent_Identity=26.1096605744125, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790346, Length=227, Percent_Identity=29.5154185022026, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1788279, Length=266, Percent_Identity=27.8195488721804, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787894, Length=228, Percent_Identity=27.6315789473684, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1790300, Length=242, Percent_Identity=28.9256198347107, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082128, Length=258, Percent_Identity=27.5193798449612, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1789403, Length=203, Percent_Identity=28.0788177339901, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64593; Mature: 64462

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFRWKLMLSYLLLILLLSGSYYLSFDHSAQSYFLDESRENLISQTRLAKLLAEQERDTM
CCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PPQQLAERIGSAIKARVTLIDRSGLVRGDSDVSKVELSHLENHLKRPEVVQAMQGGIGSS
CHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCC
LRYSETLKTDMLYTALGYESNGHYGFIRLSLPLERLSSATAALHRMTAGSVGMALLAALA
CCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FSLLLSRVTSRPLREMAEVAARIGRDGEYSRIPVASQDEIGALASVLNDMAERIDAQMHG
HHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
LDAEKTRLDAILRGMGEGVMVASADGAITLVNPAFRKMFAMTDGVEGKKLIEVCRNPDLQ
CCHHHHHHHHHHHCCCCCEEEEECCCCEEEECHHHHHHHHHCCCCCHHHHHHHHCCCCHH
AAFHDLARCGGELSREIRIQPGDVTLLTHWVPLAMDGAGQGVVAVFHDITDMKHVEEMRR
HHHHHHHHHCHHHCCEEEECCCCEEEEEEHHHHEECCCCCCHHHHHHHHHHHHHHHHHHH
DFVANVSHELRTPVSVIKGYAETLMQNDMLVSEPEHATRFVEIIRRHAERLTTLINDILT
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LSCLEARNSALELNAMDVGTTIAKSCALLAPRAAEKKICLHNEVGNNLPRTLVDQGRLEQ
HHHHHHCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCEEHHHHCCCCCHHHHCCHHHHH
VLVNLIDNAVKYTPEGGTIRLFAEQGETFLRISVQDSGIGIPPRDLPRIFERFYRVDEGR
HHHHHHHHHHEECCCCCEEEEEEECCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
SREQGGTGLGLAIAKHIVQLHGGELTVTSTPGKGSTFSFTLRMATNS
CCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEEECCC
>Mature Secondary Structure 
TFRWKLMLSYLLLILLLSGSYYLSFDHSAQSYFLDESRENLISQTRLAKLLAEQERDTM
CCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PPQQLAERIGSAIKARVTLIDRSGLVRGDSDVSKVELSHLENHLKRPEVVQAMQGGIGSS
CHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCC
LRYSETLKTDMLYTALGYESNGHYGFIRLSLPLERLSSATAALHRMTAGSVGMALLAALA
CCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FSLLLSRVTSRPLREMAEVAARIGRDGEYSRIPVASQDEIGALASVLNDMAERIDAQMHG
HHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
LDAEKTRLDAILRGMGEGVMVASADGAITLVNPAFRKMFAMTDGVEGKKLIEVCRNPDLQ
CCHHHHHHHHHHHCCCCCEEEEECCCCEEEECHHHHHHHHHCCCCCHHHHHHHHCCCCHH
AAFHDLARCGGELSREIRIQPGDVTLLTHWVPLAMDGAGQGVVAVFHDITDMKHVEEMRR
HHHHHHHHHCHHHCCEEEECCCCEEEEEEHHHHEECCCCCCHHHHHHHHHHHHHHHHHHH
DFVANVSHELRTPVSVIKGYAETLMQNDMLVSEPEHATRFVEIIRRHAERLTTLINDILT
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LSCLEARNSALELNAMDVGTTIAKSCALLAPRAAEKKICLHNEVGNNLPRTLVDQGRLEQ
HHHHHHCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCEEHHHHCCCCCHHHHCCHHHHH
VLVNLIDNAVKYTPEGGTIRLFAEQGETFLRISVQDSGIGIPPRDLPRIFERFYRVDEGR
HHHHHHHHHHEECCCCCEEEEEEECCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
SREQGGTGLGLAIAKHIVQLHGGELTVTSTPGKGSTFSFTLRMATNS
CCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]