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The map label for this gene is phoP [H]

Identifier: 118581556

GI number: 118581556

Start: 3461749

End: 3462435

Strand: Direct

Name: phoP [H]

Synonym: Ppro_3155

Alternate gene names: 118581556

Gene position: 3461749-3462435 (Clockwise)

Preceding gene: 118581555

Following gene: 118581557

Centisome position: 86.37

GC content: 63.32

Gene sequence:

>687_bases
ATGAAACAGAGGATCCTGATCATCGAAGACGAGCGGGACCTTGCCGAGCTTTTGGCCTTCAACCTGGAGAAGGAGGGGTT
TGCGCCCCGCTGCGCCTTTGACGGCATTTCAGGGCTCGAGGCGGCCCGCGACAGCAAGCCCGACCTGATCGTCCTGGACC
TGATGCTGCCCGGAATGCTGGGCACCGAGGTCTGCAAGGCCCTGCGCAAGGACACGACCACCAGCCGCATACCGGTCCTG
ATGGTCACCGCCAAGGGGGACGAGATCGACCGGGTGGTGGGGTTCGAGCTGGGGGCCGACGACTATATCGTCAAGCCCTT
CTCCATGCGGGAACTCTGCCTGCGCATCAGGGCAATTCTCAGGCGCTGCGACGTTGAACAGCCAACCGGATCGCCGCTTC
TCACCCTGGGTGATATCGTCATCGACCGGGAGCGCCACCGGGTGGTCAGCGCCGATGCGGAAACCGACCTGACCTCCACG
GAGTTCAAGCTGCTGCTCTACCTGGTGGAGCGCCGCGGCCGGGTAATCAGCCGGGACCAGCTGCTGCAGGACGTGTGGAG
CTACCATGATGTGGGGGATACGCGCACCGTGGATACGCACATCACCCGACTGCGCGGCAAGCTGGGCGCTCCGGGAGAGC
AGATCAAGACGGTTCGGGGTTTCGGCTACAAAATCGAGGAGAACTAG

Upstream 100 bases:

>100_bases
ATTTTACAAATCGACACAGAGTTGTAACATTCCTATGTTACAAGCTCATGAATCGTACACGGATACAGTGTGTCAGATCA
CGACCACCGAGGAGTCACCC

Downstream 100 bases:

>100_bases
TCCCATGACATTCCGCTGGAAACTGATGCTTTCCTACCTGCTGCTGATTCTCTTGCTGTCCGGCTCCTATTACCTGAGTT
TCGATCACAGCGCCCAGAGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKQRILIIEDERDLAELLAFNLEKEGFAPRCAFDGISGLEAARDSKPDLIVLDLMLPGMLGTEVCKALRKDTTTSRIPVL
MVTAKGDEIDRVVGFELGADDYIVKPFSMRELCLRIRAILRRCDVEQPTGSPLLTLGDIVIDRERHRVVSADAETDLTST
EFKLLLYLVERRGRVISRDQLLQDVWSYHDVGDTRTVDTHITRLRGKLGAPGEQIKTVRGFGYKIEEN

Sequences:

>Translated_228_residues
MKQRILIIEDERDLAELLAFNLEKEGFAPRCAFDGISGLEAARDSKPDLIVLDLMLPGMLGTEVCKALRKDTTTSRIPVL
MVTAKGDEIDRVVGFELGADDYIVKPFSMRELCLRIRAILRRCDVEQPTGSPLLTLGDIVIDRERHRVVSADAETDLTST
EFKLLLYLVERRGRVISRDQLLQDVWSYHDVGDTRTVDTHITRLRGKLGAPGEQIKTVRGFGYKIEEN
>Mature_228_residues
MKQRILIIEDERDLAELLAFNLEKEGFAPRCAFDGISGLEAARDSKPDLIVLDLMLPGMLGTEVCKALRKDTTTSRIPVL
MVTAKGDEIDRVVGFELGADDYIVKPFSMRELCLRIRAILRRCDVEQPTGSPLLTLGDIVIDRERHRVVSADAETDLTST
EFKLLLYLVERRGRVISRDQLLQDVWSYHDVGDTRTVDTHITRLRGKLGAPGEQIKTVRGFGYKIEEN

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=43.0434782608696, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=43.3476394849785, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=40.6113537117904, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=36.8888888888889, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=43.9655172413793, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=37.5, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=37.719298245614, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=34.6666666666667, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=34.2222222222222, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=34.375, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=33.7719298245614, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=29.7777777777778, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=29.8701298701299, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=31.0344827586207, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788550, Length=119, Percent_Identity=33.6134453781513, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25728; Mature: 25728

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRILIIEDERDLAELLAFNLEKEGFAPRCAFDGISGLEAARDSKPDLIVLDLMLPGML
CCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCHH
GTEVCKALRKDTTTSRIPVLMVTAKGDEIDRVVGFELGADDYIVKPFSMRELCLRIRAIL
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHEECEEECCCCEEECCCCHHHHHHHHHHHH
RRCDVEQPTGSPLLTLGDIVIDRERHRVVSADAETDLTSTEFKLLLYLVERRGRVISRDQ
HHCCCCCCCCCCEEEHHHHHCCCCHHEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHH
LLQDVWSYHDVGDTRTVDTHITRLRGKLGAPGEQIKTVRGFGYKIEEN
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCC
>Mature Secondary Structure
MKQRILIIEDERDLAELLAFNLEKEGFAPRCAFDGISGLEAARDSKPDLIVLDLMLPGML
CCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCHH
GTEVCKALRKDTTTSRIPVLMVTAKGDEIDRVVGFELGADDYIVKPFSMRELCLRIRAIL
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHEECEEECCCCEEECCCCHHHHHHHHHHHH
RRCDVEQPTGSPLLTLGDIVIDRERHRVVSADAETDLTSTEFKLLLYLVERRGRVISRDQ
HHCCCCCCCCCCEEEHHHHHCCCCHHEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHH
LLQDVWSYHDVGDTRTVDTHITRLRGKLGAPGEQIKTVRGFGYKIEEN
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]