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The map label for this gene is lolA [H]

Identifier: 118581495

GI number: 118581495

Start: 3381742

End: 3382470

Strand: Direct

Name: lolA [H]

Synonym: Ppro_3092

Alternate gene names: 118581495

Gene position: 3381742-3382470 (Clockwise)

Preceding gene: 118581494

Following gene: 118581496

Centisome position: 84.37

GC content: 60.49

Gene sequence:

>729_bases
ATGAAATGCCGATCACGCATGTTTTCCAGTCTTTTCGCACTGTTCCTGCTGGTCATGACCTCATACCCGGCCCTGGCAGC
GGAACACCCGGCAACGCTCAGCGATGTGGTCAGCGCCCTGGAGAAGGGTTACGCCACGCTCCAGGACGTTCAGGCCGACT
TCAGCCAGAGGACCAGCGTGGCCGGCATGAAAAGAGAACAGCGCGGCAACGGAGAAATGCTCCTGAAGCGACCCGGTTCT
TCCACGGCCATGTTCCGCTTCAACTATGCCAGGCCGAAGCAGCAGATCGTCTCCAACGGAAAGCAGGTCTGGTTCTACCT
CCCCGACAGCAACCAGGTGATGGTGTCGTCCATGGAAGCCATGTTCAAGGGGGGCAATTCCATCGCACTCTCCTACCTGA
CCGGCATGGGGCATGTCTCCCGCGACTTCTCCATAAGCTTCGCCCGGGAACGCCAGGACAAAAACGGCAACTACCAGCTG
GAGCTGCTGCCCAAAAAGCCCACCGCGGTGCTGGCCCGGCTGTCACTCAGCGTCTCGGGAGAGGCGGTAGCCCGCTACCT
GAGACAGGGGAACGTGAGGGACATCTTCCCCATCGTCTCTTCCGTCGTTGTTGACGCAGGCGGCAACCAGACCCGCATCG
ACTACGGCCGGGCAAGGGTCAACAGGGGCATAAGCAGCTCGAAGTTCACCTTCAGGCCCCCCCCGGGGGTGGACGTCATA
CAACAGTAA

Upstream 100 bases:

>100_bases
ATTCGTCAAAGCGGTTGCGATGACGCCCCTGTTATGGCACAGTAACCGATCACTGACCGGAGCCATCCCCTGGCGCCGTT
CCCGGAGGAGATACCAATCC

Downstream 100 bases:

>100_bases
GGTTTTGACACGAACCAGGAACAGAGGGCCTGGCTGCGGCTTCCGAACTCTGTAGCCAGGCTTCTGCCTTTGCAACGATT
TTCACATTTCCCATGGGAGG

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MKCRSRMFSSLFALFLLVMTSYPALAAEHPATLSDVVSALEKGYATLQDVQADFSQRTSVAGMKREQRGNGEMLLKRPGS
STAMFRFNYARPKQQIVSNGKQVWFYLPDSNQVMVSSMEAMFKGGNSIALSYLTGMGHVSRDFSISFARERQDKNGNYQL
ELLPKKPTAVLARLSLSVSGEAVARYLRQGNVRDIFPIVSSVVVDAGGNQTRIDYGRARVNRGISSSKFTFRPPPGVDVI
QQ

Sequences:

>Translated_242_residues
MKCRSRMFSSLFALFLLVMTSYPALAAEHPATLSDVVSALEKGYATLQDVQADFSQRTSVAGMKREQRGNGEMLLKRPGS
STAMFRFNYARPKQQIVSNGKQVWFYLPDSNQVMVSSMEAMFKGGNSIALSYLTGMGHVSRDFSISFARERQDKNGNYQL
ELLPKKPTAVLARLSLSVSGEAVARYLRQGNVRDIFPIVSSVVVDAGGNQTRIDYGRARVNRGISSSKFTFRPPPGVDVI
QQ
>Mature_242_residues
MKCRSRMFSSLFALFLLVMTSYPALAAEHPATLSDVVSALEKGYATLQDVQADFSQRTSVAGMKREQRGNGEMLLKRPGS
STAMFRFNYARPKQQIVSNGKQVWFYLPDSNQVMVSSMEAMFKGGNSIALSYLTGMGHVSRDFSISFARERQDKNGNYQL
ELLPKKPTAVLARLSLSVSGEAVARYLRQGNVRDIFPIVSSVVVDAGGNQTRIDYGRARVNRGISSSKFTFRPPPGVDVI
QQ

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family [H]

Homologues:

None

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004564
- InterPro:   IPR018323 [H]

Pfam domain/function: PF03548 LolA [H]

EC number: NA

Molecular weight: Translated: 26793; Mature: 26793

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCRSRMFSSLFALFLLVMTSYPALAAEHPATLSDVVSALEKGYATLQDVQADFSQRTSV
CCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGMKREQRGNGEMLLKRPGSSTAMFRFNYARPKQQIVSNGKQVWFYLPDSNQVMVSSMEA
HHHHHHHCCCCCEEEECCCCCEEEEEEECCCCHHHHHCCCCEEEEEECCCCCHHHHHHHH
MFKGGNSIALSYLTGMGHVSRDFSISFARERQDKNGNYQLELLPKKPTAVLARLSLSVSG
HHCCCCEEEEEEHHCCCCCCCCCEEEEHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCH
EAVARYLRQGNVRDIFPIVSSVVVDAGGNQTRIDYGRARVNRGISSSKFTFRPPPGVDVI
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCEEECCCCCCHHC
QQ
CC
>Mature Secondary Structure
MKCRSRMFSSLFALFLLVMTSYPALAAEHPATLSDVVSALEKGYATLQDVQADFSQRTSV
CCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGMKREQRGNGEMLLKRPGSSTAMFRFNYARPKQQIVSNGKQVWFYLPDSNQVMVSSMEA
HHHHHHHCCCCCEEEECCCCCEEEEEEECCCCHHHHHCCCCEEEEEECCCCCHHHHHHHH
MFKGGNSIALSYLTGMGHVSRDFSISFARERQDKNGNYQLELLPKKPTAVLARLSLSVSG
HHCCCCEEEEEEHHCCCCCCCCCEEEEHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCH
EAVARYLRQGNVRDIFPIVSSVVVDAGGNQTRIDYGRARVNRGISSSKFTFRPPPGVDVI
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCEEECCCCCCHHC
QQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA