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The map label for this gene is cheA [H]

Identifier: 118581494

GI number: 118581494

Start: 3379981

End: 3381597

Strand: Direct

Name: cheA [H]

Synonym: Ppro_3091

Alternate gene names: 118581494

Gene position: 3379981-3381597 (Clockwise)

Preceding gene: 118581493

Following gene: 118581495

Centisome position: 84.33

GC content: 65.62

Gene sequence:

>1617_bases
ATGGACATTTCCCAGTACCGGGATCTGTTCGTCTCCGAGGCCCGCCGGCACCTGGAGGCATTCAACAGCCTCATCGTCCA
GCTGGAGAGCAGCCCCGACGCGAAAGGCATACACGAACTCTTCCGCCATGCCCATTCACTCAAGGGCATGGCGGCCACCA
TGCAGTTCGACCGCATCGCCACCCTGGCCCACCACCTGGAAGACCTGCTGGCCGCGGTCCGCGACGGCGGTTCCGCTCCC
GATGCGAGGCTGTGCGACATCCTGCTGGAGGGAGGCGACCTGCTGACCGCCATGGTAACGGTCATCGAAGCGGGTAATGG
AGCAGACCTGCCCGATACGGAGCACCTGACCCAACGAATCGTCGACTTCGCCCCCGCCCAGGAAAAGCCCAGCCACCCCG
AAACAACCGCAACAGACCAGCCCTCCCCCCCCCTACACCAGTTCAGACAGTCCGACTCGTTCACAACCGTCCGGGTAAAG
GCCGAAACCCTCGATCGCATGGTCACGATCACCGGCGAGCTGATCACCACCCAGCACCGCCTGGCGGAGCGCTGCAGATC
CGCGTCAGACCAGGACTTACACGAGCCGTTGAGCCAGCTTGCCCACCACCTGCGCGAGCTGCGCGACGAAATATTCTTGG
CGCGCATGCTCCCCTTTTCCGTAGTGGCGGAACGCTTCCCCCGGCTGGTGCGCGACCTGGCCCGGGAACGGCACAAGGAG
ATCAGGCTCTGCATCGGCGGAGGAGAGATCGAGCTCGACCGGGGAATCCTGGAGGCGATCGTCGAGCCGCTGGTTCACCT
GCTGCGCAATGCCGTGGACCACGGCCTGGAGCCCGCCACGGAGCGCATGGCGGCAGGAAAGGAGCGCTGCGGCCTGATCA
CTCTGACCGTCAGCCGGGACAGGGATCAGGTCAGCATCCAGGTCGCCGATGACGGGCGGGGCCTGGATCCGGGCCGTCTG
GTCGCCAGGGCGCTGGAGCGGGGAGAGATCAGTCCGGGCCAGGCAGCCGCCCTGTCAGCCGACGAGGCGCTGATACTGAT
CTGCGCCCCCGGCTTCTCCACCGCGGAAACGGTCACCGATACCTCCGGCCGCGGGGTGGGCATGGATGCGGTCAGAAGCA
CCGTCCGCAGCCTGGGCGGAAGCATCTCCATCCAGTCTGCGGTCGGCATGGGGAGCTGCTTCACGCTCACCCTTCCCCTG
ACCGTCTCCATCATCCAGGCCCTGCTGGTGGAGTGCGGCCCGCTGACCGTCGCCTTCCCGGTCAGCGCAGTGGAGCGGAC
CCTCGAGCTCACCGGCACTGATATCGTAGAACAGGACGGCCACCGCTTCTGCTCATCCGCAGGAGCCAGCATTCCGCTCT
TGGGCCTTCACCAGGTACTGGGCTGCCCCCCTCCCGTGCGGACGCCCCGGCACGTTCCGGTTATCGTCAGCAGGATCAAC
GGAAAGCTGACAGGCCTTGCGGTCGACGCCATCAGCGGGCAGCGGGAAATCTTCGTCAAGCCGCTGGGCAGGCCCTTGTC
GCAGCTGAAAAACAGCAGCGGCGGCGCAATCCTGGGCAACGGCCGCATCGTCTTTGTCATGGATGTGAACACCTTGGACT
TAGGAAGTCCCGCCTGA

Upstream 100 bases:

>100_bases
ATCCAGAAGGCACTGGAGCTGGGAGCAAAGGCATTCATCCAGAAACCGCTCACCCCGGAAAAGGTGATCTCCGCGCTGTC
GCACATGGAGGCATAGCACC

Downstream 100 bases:

>100_bases
TTGCCTGACCTACGGCACCCATACACCAGGCGGCGCGGATCCCGATTCGTCAAAGCGGTTGCGATGACGCCCCTGTTATG
GCACAGTAACCGATCACTGA

Product: signal transduction histidine kinase CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MDISQYRDLFVSEARRHLEAFNSLIVQLESSPDAKGIHELFRHAHSLKGMAATMQFDRIATLAHHLEDLLAAVRDGGSAP
DARLCDILLEGGDLLTAMVTVIEAGNGADLPDTEHLTQRIVDFAPAQEKPSHPETTATDQPSPPLHQFRQSDSFTTVRVK
AETLDRMVTITGELITTQHRLAERCRSASDQDLHEPLSQLAHHLRELRDEIFLARMLPFSVVAERFPRLVRDLARERHKE
IRLCIGGGEIELDRGILEAIVEPLVHLLRNAVDHGLEPATERMAAGKERCGLITLTVSRDRDQVSIQVADDGRGLDPGRL
VARALERGEISPGQAAALSADEALILICAPGFSTAETVTDTSGRGVGMDAVRSTVRSLGGSISIQSAVGMGSCFTLTLPL
TVSIIQALLVECGPLTVAFPVSAVERTLELTGTDIVEQDGHRFCSSAGASIPLLGLHQVLGCPPPVRTPRHVPVIVSRIN
GKLTGLAVDAISGQREIFVKPLGRPLSQLKNSSGGAILGNGRIVFVMDVNTLDLGSPA

Sequences:

>Translated_538_residues
MDISQYRDLFVSEARRHLEAFNSLIVQLESSPDAKGIHELFRHAHSLKGMAATMQFDRIATLAHHLEDLLAAVRDGGSAP
DARLCDILLEGGDLLTAMVTVIEAGNGADLPDTEHLTQRIVDFAPAQEKPSHPETTATDQPSPPLHQFRQSDSFTTVRVK
AETLDRMVTITGELITTQHRLAERCRSASDQDLHEPLSQLAHHLRELRDEIFLARMLPFSVVAERFPRLVRDLARERHKE
IRLCIGGGEIELDRGILEAIVEPLVHLLRNAVDHGLEPATERMAAGKERCGLITLTVSRDRDQVSIQVADDGRGLDPGRL
VARALERGEISPGQAAALSADEALILICAPGFSTAETVTDTSGRGVGMDAVRSTVRSLGGSISIQSAVGMGSCFTLTLPL
TVSIIQALLVECGPLTVAFPVSAVERTLELTGTDIVEQDGHRFCSSAGASIPLLGLHQVLGCPPPVRTPRHVPVIVSRIN
GKLTGLAVDAISGQREIFVKPLGRPLSQLKNSSGGAILGNGRIVFVMDVNTLDLGSPA
>Mature_538_residues
MDISQYRDLFVSEARRHLEAFNSLIVQLESSPDAKGIHELFRHAHSLKGMAATMQFDRIATLAHHLEDLLAAVRDGGSAP
DARLCDILLEGGDLLTAMVTVIEAGNGADLPDTEHLTQRIVDFAPAQEKPSHPETTATDQPSPPLHQFRQSDSFTTVRVK
AETLDRMVTITGELITTQHRLAERCRSASDQDLHEPLSQLAHHLRELRDEIFLARMLPFSVVAERFPRLVRDLARERHKE
IRLCIGGGEIELDRGILEAIVEPLVHLLRNAVDHGLEPATERMAAGKERCGLITLTVSRDRDQVSIQVADDGRGLDPGRL
VARALERGEISPGQAAALSADEALILICAPGFSTAETVTDTSGRGVGMDAVRSTVRSLGGSISIQSAVGMGSCFTLTLPL
TVSIIQALLVECGPLTVAFPVSAVERTLELTGTDIVEQDGHRFCSSAGASIPLLGLHQVLGCPPPVRTPRHVPVIVSRIN
GKLTGLAVDAISGQREIFVKPLGRPLSQLKNSSGGAILGNGRIVFVMDVNTLDLGSPA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=446, Percent_Identity=32.9596412556054, Blast_Score=246, Evalue=4e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57955; Mature: 57955

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDISQYRDLFVSEARRHLEAFNSLIVQLESSPDAKGIHELFRHAHSLKGMAATMQFDRIA
CCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
TLAHHLEDLLAAVRDGGSAPDARLCDILLEGGDLLTAMVTVIEAGNGADLPDTEHLTQRI
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
VDFAPAQEKPSHPETTATDQPSPPLHQFRQSDSFTTVRVKAETLDRMVTITGELITTQHR
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHH
LAERCRSASDQDLHEPLSQLAHHLRELRDEIFLARMLPFSVVAERFPRLVRDLARERHKE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
IRLCIGGGEIELDRGILEAIVEPLVHLLRNAVDHGLEPATERMAAGKERCGLITLTVSRD
EEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHCCEEEEEEECC
RDQVSIQVADDGRGLDPGRLVARALERGEISPGQAAALSADEALILICAPGFSTAETVTD
CCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCEECCCCEEEEEECCCCCCHHHCCC
TSGRGVGMDAVRSTVRSLGGSISIQSAVGMGSCFTLTLPLTVSIIQALLVECGPLTVAFP
CCCCCCCHHHHHHHHHHCCCCEEEHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEE
VSAVERTLELTGTDIVEQDGHRFCSSAGASIPLLGLHQVLGCPPPVRTPRHVPVIVSRIN
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHEECC
GKLTGLAVDAISGQREIFVKPLGRPLSQLKNSSGGAILGNGRIVFVMDVNTLDLGSPA
CCEEEEEEECCCCCCEEEECCCCHHHHHHCCCCCCEEEECCEEEEEEECCEECCCCCC
>Mature Secondary Structure
MDISQYRDLFVSEARRHLEAFNSLIVQLESSPDAKGIHELFRHAHSLKGMAATMQFDRIA
CCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
TLAHHLEDLLAAVRDGGSAPDARLCDILLEGGDLLTAMVTVIEAGNGADLPDTEHLTQRI
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
VDFAPAQEKPSHPETTATDQPSPPLHQFRQSDSFTTVRVKAETLDRMVTITGELITTQHR
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHH
LAERCRSASDQDLHEPLSQLAHHLRELRDEIFLARMLPFSVVAERFPRLVRDLARERHKE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
IRLCIGGGEIELDRGILEAIVEPLVHLLRNAVDHGLEPATERMAAGKERCGLITLTVSRD
EEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHCCEEEEEEECC
RDQVSIQVADDGRGLDPGRLVARALERGEISPGQAAALSADEALILICAPGFSTAETVTD
CCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCEECCCCEEEEEECCCCCCHHHCCC
TSGRGVGMDAVRSTVRSLGGSISIQSAVGMGSCFTLTLPLTVSIIQALLVECGPLTVAFP
CCCCCCCHHHHHHHHHHCCCCEEEHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEE
VSAVERTLELTGTDIVEQDGHRFCSSAGASIPLLGLHQVLGCPPPVRTPRHVPVIVSRIN
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHEECC
GKLTGLAVDAISGQREIFVKPLGRPLSQLKNSSGGAILGNGRIVFVMDVNTLDLGSPA
CCEEEEEEECCCCCCEEEECCCCHHHHHHCCCCCCEEEECCEEEEEEECCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]