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The map label for this gene is lpxA [H]

Identifier: 118581426

GI number: 118581426

Start: 3301183

End: 3301962

Strand: Direct

Name: lpxA [H]

Synonym: Ppro_3021

Alternate gene names: 118581426

Gene position: 3301183-3301962 (Clockwise)

Preceding gene: 118581425

Following gene: 118581427

Centisome position: 82.36

GC content: 63.85

Gene sequence:

>780_bases
ATGATACATCCCAGCGCGATCATTGACAGCAGCGCGGAGCTGGCGGCAGACGTCGAGGTAGGCCCCTACGCCATTATCGG
CAAAAAGGTCAGCATCGGCAGCGGGACCAGCATCGGCCCCCATGCCGTGATCGGCGACTTTACCACCATCGGCGAAAACA
ACCAGATCTTCCACCAGAGCTCCGTAGGCGCAGCGCCGCAGGACCTGAAGTACCGCGGCGAAGAGTGTTGGACCCGCATC
GGCGACAAGAACATCATCCGCGAATTCGCCACCATCCATCGCGGCACGGTCACCGGCCATGGCGAGACCCTGGTCGGAAG
CGGCAACCTGTTCATGGCCTACTCCCACGTGGCCCACGACTGCCGCATCGGCAATGGCGTGGTCATGGCCAACGTGGCCA
CCCTGGCCGGACACGTCACCGTGGAGGACAACGTCATCCTGGGCGGGCTGGTGGCGGTGCACCAGTTCTCCACCATCGGC
AGCCATGCCATGATCGGCGGCGGAACCATGGTCGGCCTGGACATCGTCCCCTACTGCATCGCCACCTCCGGCAAGCGGGA
CGCCAAACTGCGCGGCCTGAACCTGATCGGGCTGAAGCGGCGCGGCTTCTCCGACGAAGCCATCTCCAGCCTGAAGAAAG
CCTACAAGACCCTCTTCATGGCCAACCTGAAGCTCGCCGACGCCATCAGCCGCATCAGGAGCGAAACCAGCGTCTGTGCC
GAGGTGGAGTACATGCTGGCCTTCATCGAGCGCTCGGAGCGGGGCATCTGCCGGGGATGA

Upstream 100 bases:

>100_bases
CGGCACAATAATGGACCAGGGCGGGCGCCTGAGCGCGTCCCCGCCCTGGTCCGCGTACCGTTCCTCCCTCACCCTTAGGT
TTCGACTCGGAGAGCACCCC

Downstream 100 bases:

>100_bases
ACGATCAGTCAGCCACAGCGGCGGCCCCCTTAAGGACCGCCGTAATCGGTGTGGGCTACCTGGGCAGCTTCCACGCCCAG
AAGTACGCAGCCATCCCGGA

Product: acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MIHPSAIIDSSAELAADVEVGPYAIIGKKVSIGSGTSIGPHAVIGDFTTIGENNQIFHQSSVGAAPQDLKYRGEECWTRI
GDKNIIREFATIHRGTVTGHGETLVGSGNLFMAYSHVAHDCRIGNGVVMANVATLAGHVTVEDNVILGGLVAVHQFSTIG
SHAMIGGGTMVGLDIVPYCIATSGKRDAKLRGLNLIGLKRRGFSDEAISSLKKAYKTLFMANLKLADAISRIRSETSVCA
EVEYMLAFIERSERGICRG

Sequences:

>Translated_259_residues
MIHPSAIIDSSAELAADVEVGPYAIIGKKVSIGSGTSIGPHAVIGDFTTIGENNQIFHQSSVGAAPQDLKYRGEECWTRI
GDKNIIREFATIHRGTVTGHGETLVGSGNLFMAYSHVAHDCRIGNGVVMANVATLAGHVTVEDNVILGGLVAVHQFSTIG
SHAMIGGGTMVGLDIVPYCIATSGKRDAKLRGLNLIGLKRRGFSDEAISSLKKAYKTLFMANLKLADAISRIRSETSVCA
EVEYMLAFIERSERGICRG
>Mature_259_residues
MIHPSAIIDSSAELAADVEVGPYAIIGKKVSIGSGTSIGPHAVIGDFTTIGENNQIFHQSSVGAAPQDLKYRGEECWTRI
GDKNIIREFATIHRGTVTGHGETLVGSGNLFMAYSHVAHDCRIGNGVVMANVATLAGHVTVEDNVILGGLVAVHQFSTIG
SHAMIGGGTMVGLDIVPYCIATSGKRDAKLRGLNLIGLKRRGFSDEAISSLKKAYKTLFMANLKLADAISRIRSETSVCA
EVEYMLAFIERSERGICRG

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=258, Percent_Identity=46.1240310077519, Blast_Score=234, Evalue=5e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 27514; Mature: 27514

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHPSAIIDSSAELAADVEVGPYAIIGKKVSIGSGTSIGPHAVIGDFTTIGENNQIFHQS
CCCCCHHCCCCCHHEEECCCCCEEEEECEEECCCCCCCCCCEEECCEEEECCCCCEEECC
SVGAAPQDLKYRGEECWTRIGDKNIIREFATIHRGTVTGHGETLVGSGNLFMAYSHVAHD
CCCCCCHHHHHCCHHHHHHCCCHHHHHHHHHHHCCEECCCCCEEEECCCEEEEEHHHHHH
CRIGNGVVMANVATLAGHVTVEDNVILGGLVAVHQFSTIGSHAMIGGGTMVGLDIVPYCI
CCCCCCEEEEEHHHHHEEEEEECCEEEHHHHHHHHHHHCCCCEEECCCEEEHHHHHHHHH
ATSGKRDAKLRGLNLIGLKRRGFSDEAISSLKKAYKTLFMANLKLADAISRIRSETSVCA
HCCCCCCCEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
EVEYMLAFIERSERGICRG
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIHPSAIIDSSAELAADVEVGPYAIIGKKVSIGSGTSIGPHAVIGDFTTIGENNQIFHQS
CCCCCHHCCCCCHHEEECCCCCEEEEECEEECCCCCCCCCCEEECCEEEECCCCCEEECC
SVGAAPQDLKYRGEECWTRIGDKNIIREFATIHRGTVTGHGETLVGSGNLFMAYSHVAHD
CCCCCCHHHHHCCHHHHHHCCCHHHHHHHHHHHCCEECCCCCEEEECCCEEEEEHHHHHH
CRIGNGVVMANVATLAGHVTVEDNVILGGLVAVHQFSTIGSHAMIGGGTMVGLDIVPYCI
CCCCCCEEEEEHHHHHEEEEEECCEEEHHHHHHHHHHHCCCCEEECCCEEEHHHHHHHHH
ATSGKRDAKLRGLNLIGLKRRGFSDEAISSLKKAYKTLFMANLKLADAISRIRSETSVCA
HCCCCCCCEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
EVEYMLAFIERSERGICRG
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA