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The map label for this gene is fabZ [H]

Identifier: 118581425

GI number: 118581425

Start: 3300628

End: 3301071

Strand: Direct

Name: fabZ [H]

Synonym: Ppro_3020

Alternate gene names: 118581425

Gene position: 3300628-3301071 (Clockwise)

Preceding gene: 118581424

Following gene: 118581426

Centisome position: 82.35

GC content: 61.49

Gene sequence:

>444_bases
ATGTTACTGGATGTCAATGAAATCATGAAGATCCTGCCGCACCGTTTCCCGTTTCTCATGGTGGACCGCGTCATCGAACT
GGAGCCCGGCAAACGCTGCGTCGGACTCAAGAACGTGACCATCAACGAGCCGTTTTTCCAGGGACACTTTCCCGGCCACC
CGGTCATGCCGGGCGTGCTGATCGTGGAGGCCATGGCCCAGGTTGCCGGCATCATGGCCTATATGGCGTCGGACGACCGC
ACCAAGAAGAAGGTCAGCTACTTCATGTCCATCGACAGCGCCAAGTTCCGCAAGCCGGTCTTCCCCGGCGACCAGCTGCG
CATCGAGGTGGAGACAACCATGAACCGGCGCGGCATCTGGGGCGTCAACGGCAAGGTCTACGTGGACGGCACGCTGGTCA
CCGAGGCGGCCCTCAAGGCTACCTTCGCCGACGCGGCGGACTGA

Upstream 100 bases:

>100_bases
CATGCCGGAAACGCCCGGAGCGGGGCAGTTCATACCGGAATAATCCGAAGGATGCCACGCAACCGGACGTACATTAACCA
GATAAAAAGGGGGAATACCC

Downstream 100 bases:

>100_bases
TCGCCGTCTGCCGGCACAATAATGGACCAGGGCGGGCGCCTGAGCGCGTCCCCGCCCTGGTCCGCGTACCGTTCCTCCCT
CACCCTTAGGTTTCGACTCG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MLLDVNEIMKILPHRFPFLMVDRVIELEPGKRCVGLKNVTINEPFFQGHFPGHPVMPGVLIVEAMAQVAGIMAYMASDDR
TKKKVSYFMSIDSAKFRKPVFPGDQLRIEVETTMNRRGIWGVNGKVYVDGTLVTEAALKATFADAAD

Sequences:

>Translated_147_residues
MLLDVNEIMKILPHRFPFLMVDRVIELEPGKRCVGLKNVTINEPFFQGHFPGHPVMPGVLIVEAMAQVAGIMAYMASDDR
TKKKVSYFMSIDSAKFRKPVFPGDQLRIEVETTMNRRGIWGVNGKVYVDGTLVTEAALKATFADAAD
>Mature_147_residues
MLLDVNEIMKILPHRFPFLMVDRVIELEPGKRCVGLKNVTINEPFFQGHFPGHPVMPGVLIVEAMAQVAGIMAYMASDDR
TKKKVSYFMSIDSAKFRKPVFPGDQLRIEVETTMNRRGIWGVNGKVYVDGTLVTEAALKATFADAAD

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=136, Percent_Identity=50.7352941176471, Blast_Score=152, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 16416; Mature: 16416

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLDVNEIMKILPHRFPFLMVDRVIELEPGKRCVGLKNVTINEPFFQGHFPGHPVMPGVL
CEECHHHHHHHHCCCCCHHHHHHEEECCCCCEEEEECCCEECCCCCCCCCCCCCCCCHHH
IVEAMAQVAGIMAYMASDDRTKKKVSYFMSIDSAKFRKPVFPGDQLRIEVETTMNRRGIW
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHCCCCCCCCEEEEEEEECCCCCCEE
GVNGKVYVDGTLVTEAALKATFADAAD
CCCCEEEECCEEHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLLDVNEIMKILPHRFPFLMVDRVIELEPGKRCVGLKNVTINEPFFQGHFPGHPVMPGVL
CEECHHHHHHHHCCCCCHHHHHHEEECCCCCEEEEECCCEECCCCCCCCCCCCCCCCHHH
IVEAMAQVAGIMAYMASDDRTKKKVSYFMSIDSAKFRKPVFPGDQLRIEVETTMNRRGIW
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHCCCCCCCCEEEEEEEECCCCCCEE
GVNGKVYVDGTLVTEAALKATFADAAD
CCCCEEEECCEEHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA