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The map label for this gene is glmU [H]

Identifier: 118581280

GI number: 118581280

Start: 3146382

End: 3146861

Strand: Reverse

Name: glmU [H]

Synonym: Ppro_2875

Alternate gene names: 118581280

Gene position: 3146861-3146382 (Counterclockwise)

Preceding gene: 118581281

Following gene: 118581279

Centisome position: 78.51

GC content: 51.67

Gene sequence:

>480_bases
ATGGGCGAGTATGTATGCATATCTGACGATGTAAGGCTGGGTAAAAACGTCTCACTGTCCAAATTCATTAATCTGTACGG
CTGCGAGATTGGGGACAACACAAAAGTCGGTGCTTTCGTAGAGATTCAGAAGAACGCCAGGATCGGCAGCAACTGCAAAA
TCTCCAGCCATACGTTCATCTGCGACGGGGTAGTTATTGAGGATAACGTCTTTGTCGGCCACAACGTAACATTCATAAAC
GACCTTCTTCCAAGAGCGACAACGGATGGGGGGACTTTGCAGACCGAGGCGGATTGGGTCTGTGAAAAAACCATCATCAA
ACGCGGGGCTTCCATCGGTTCCAGCGCGACGCTTTTGTGCGGCATCACGGTGGGTGAAAATGCAATCGTCGGAGCCGGAA
GCGTAGTGACAAGAGACGTCCCGCCCAATACGATCGTTGCGGGAAATCCGGCGCGGATCAAGAGATGCATAGCGCCATAG

Upstream 100 bases:

>100_bases
GTTGTCAAGATGCTTGAGGCATCAGTCAGGTCGCTGAAAAATGGGGGAGTCGTCACCTACCTGTAACACACGTGGCCGCA
TTCGAGAGAGGAATACTACT

Downstream 100 bases:

>100_bases
GAACGTCGCCGTAAAAGACCGACACAGCAGGCCATGAGCAGCTTGTCGACCTTCATGAGTCAGGGAGCGAAGGAGAGCAA
GATGGTGAATGTACCCTTTA

Product: hexapaptide repeat-containing transferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MGEYVCISDDVRLGKNVSLSKFINLYGCEIGDNTKVGAFVEIQKNARIGSNCKISSHTFICDGVVIEDNVFVGHNVTFIN
DLLPRATTDGGTLQTEADWVCEKTIIKRGASIGSSATLLCGITVGENAIVGAGSVVTRDVPPNTIVAGNPARIKRCIAP

Sequences:

>Translated_159_residues
MGEYVCISDDVRLGKNVSLSKFINLYGCEIGDNTKVGAFVEIQKNARIGSNCKISSHTFICDGVVIEDNVFVGHNVTFIN
DLLPRATTDGGTLQTEADWVCEKTIIKRGASIGSSATLLCGITVGENAIVGAGSVVTRDVPPNTIVAGNPARIKRCIAP
>Mature_158_residues
GEYVCISDDVRLGKNVSLSKFINLYGCEIGDNTKVGAFVEIQKNARIGSNCKISSHTFICDGVVIEDNVFVGHNVTFIND
LLPRATTDGGTLQTEADWVCEKTIIKRGASIGSSATLLCGITVGENAIVGAGSVVTRDVPPNTIVAGNPARIKRCIAP

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786537, Length=132, Percent_Identity=32.5757575757576, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 16799; Mature: 16668

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEYVCISDDVRLGKNVSLSKFINLYGCEIGDNTKVGAFVEIQKNARIGSNCKISSHTFI
CCCEEEEECCCCCCCCCCHHHEEEEEECEECCCCCCEEEEEEECCCCCCCCCEECCCEEE
CDGVVIEDNVFVGHNVTFINDLLPRATTDGGTLQTEADWVCEKTIIKRGASIGSSATLLC
ECCEEEECCEEECCCCHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCCEEEEE
GITVGENAIVGAGSVVTRDVPPNTIVAGNPARIKRCIAP
EEEECCCEEEECCCEEECCCCCCEEEECCHHHHHEECCC
>Mature Secondary Structure 
GEYVCISDDVRLGKNVSLSKFINLYGCEIGDNTKVGAFVEIQKNARIGSNCKISSHTFI
CCEEEEECCCCCCCCCCHHHEEEEEECEECCCCCCEEEEEEECCCCCCCCCEECCCEEE
CDGVVIEDNVFVGHNVTFINDLLPRATTDGGTLQTEADWVCEKTIIKRGASIGSSATLLC
ECCEEEECCEEECCCCHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCCEEEEE
GITVGENAIVGAGSVVTRDVPPNTIVAGNPARIKRCIAP
EEEECCCEEEECCCEEECCCCCCEEEECCHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA