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The map label for this gene is pabB [H]

Identifier: 118581215

GI number: 118581215

Start: 3072630

End: 3074408

Strand: Direct

Name: pabB [H]

Synonym: Ppro_2808

Alternate gene names: 118581215

Gene position: 3072630-3074408 (Clockwise)

Preceding gene: 118581214

Following gene: 118581216

Centisome position: 76.66

GC content: 63.46

Gene sequence:

>1779_bases
ATGCACGAAACCGTAGAGAGGCTACATCCGATCGCCCTGCTGGAATCCTTTTCCGGCGGGGAGTTCTCCCGCTCTTACCT
GTTCGAAGACTTAGAAACAATCGTGCAGGCCCACACAACGGACCAGGTCATGGCGGTATTCAGGGAGGTGGAGCAGGCGG
TAAGCCGCGGCAGGCATGCGGCAGGCTATGTGGCCTACGAGGCTGCCGGCGGACTCAATCCCGAACTGCCCAGGGGAACG
TGTGGCGACCAGCCGCTGATCTGGTTCGGCATCTTCCGCACGCGGCGCCCCTGTGACGCAACAACCGGGGCAGAAACGAA
TGATGGCCAGACAGCCTCGCCGCCGGAACTGGAGATATCCCGCCAGGAGTACGCTAGAGCGCTGGAGAAGATCAGGGAAC
ACATCGCCAGGGGCGAGACCTACCAGGTCAACTTCACCACCCGCCAGCGTTTCAGGGTCAGGGGCGATCAGTTCGCGCTC
TACCGCAGGCTGTGCAGGAACCAGCGAGCCCCCTTCTGCGCCTGGCTGGATACGGGGAGTCACCGCATCATCTCCGCTTC
ACCGGAACTGTTCTTCTCCCTTAAGGACCGGCTGTTGACCATGAAGCCGATGAAGGGAACCGCTCCCCGTCACCCCCTGG
CCGATGACGACCAACGGCGGCGGGAAGAGCTGGCTGCCAGTCCCAAGGAGCGGGCAGAGAACCTGATGATCGTCGATCTG
GTGCGCAACGACCTGTCCCGCATCGCCGACATCGGCAGCGTGGCGGTACCGGCACTGTTCCAGGTGGAGAGCTATCCCAC
GGTGCACCAGATGACCTCAACCGTCACCGCCAGGCTCAAACCGGAGGCCAGGCTGGTGGATATCTTCCAGGCCCTGTTCC
CCTGCGGCTCGGTCACCGGGGCGCCCAAGCGACGCACCATGGAGATCATTCACGACCTGGAGCGCTCTCCGCGGGGCGCC
TACTGCGGCGCCATCGGCTTCGTCTCACCCGGCGGGGAGGCGACCTTCAGCGTGGCCATCCGCACGGCAATCGTCGAATC
GACAACAGGACTGGGGGTCATGGGCATCGGCAGCGGCATCACCTGGGACTCGAACCCAGAGGCGGAATTCAGGGAATGCC
TGGACAAGAGCGCCTTCCTGACCGGACACGCAATGGATTTCGGCCTGATCGAATCCCTGCGCTGGGACGCCCAGGGCTAC
CTGCTGCTGGAGCGGCACCTGAAACGCCTGGAGCAGTCAGCGGCCCGCTTCGGCTATCCCTTTTCCCGCCGCGAACTGCT
GGATAGGCTCGTGGAGCTGGAACGCTCCCTGACCGGCGTGCACAAGGTACGGGTTCTGCTGACTTCGGCTGGCGACCTGA
TGCTGGAGCAGCAGGAGATCGACGACACCGCGGCCGAACGCCCCACCCTGTTGGTGGCGCTCGCCTCACAACGCAGCGAC
CCGTCCGATCCGCTCCTCTATCACAAGACCACCCGCCGCAGCAGGTACGATAACGAACTGCAAGCTCGGCCGGAGTGCGC
GGAGGTGATCCTGCTGAATCAGCGGGGAGAGCTGACCGAAGGATGCACCACCAACCTGGTACTCCAGCGTGGTGAGGAAC
TACTGACCCCCGCACTGCACTGCGGCCTGCTGCCGGGAACCCTGCGGGAGGAGTTGCTGCAACTGGGGGCACTCAGGGAG
GCGATCCTGACCCCGATTGATCTTGAAACCTGCGATGCATTCTGGCTGATCAACTCGGTGCGCGGCTGGAAGAAAGGGCA
GTTGCTAAAGAACTGTTAG

Upstream 100 bases:

>100_bases
ACCGCAAGATCGGCGGCATAACCGGTGACGTAATCGGCTGCATCAACGAGCTGGTGGAGATCCTTACCCTGGTCCTGATC
CCGGTCCTGGTCACGTTTGC

Downstream 100 bases:

>100_bases
CCCGACTACCTTGATGCGGACACATAAGAAACGGAAAAATGGAACGCGGATCACATCTGGAAAGTCCGGAAAAATCGGAT
AACCAACCGTTCTGAAAGAA

Product: para-aminobenzoate synthase, subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MHETVERLHPIALLESFSGGEFSRSYLFEDLETIVQAHTTDQVMAVFREVEQAVSRGRHAAGYVAYEAAGGLNPELPRGT
CGDQPLIWFGIFRTRRPCDATTGAETNDGQTASPPELEISRQEYARALEKIREHIARGETYQVNFTTRQRFRVRGDQFAL
YRRLCRNQRAPFCAWLDTGSHRIISASPELFFSLKDRLLTMKPMKGTAPRHPLADDDQRRREELAASPKERAENLMIVDL
VRNDLSRIADIGSVAVPALFQVESYPTVHQMTSTVTARLKPEARLVDIFQALFPCGSVTGAPKRRTMEIIHDLERSPRGA
YCGAIGFVSPGGEATFSVAIRTAIVESTTGLGVMGIGSGITWDSNPEAEFRECLDKSAFLTGHAMDFGLIESLRWDAQGY
LLLERHLKRLEQSAARFGYPFSRRELLDRLVELERSLTGVHKVRVLLTSAGDLMLEQQEIDDTAAERPTLLVALASQRSD
PSDPLLYHKTTRRSRYDNELQARPECAEVILLNQRGELTEGCTTNLVLQRGEELLTPALHCGLLPGTLREELLQLGALRE
AILTPIDLETCDAFWLINSVRGWKKGQLLKNC

Sequences:

>Translated_592_residues
MHETVERLHPIALLESFSGGEFSRSYLFEDLETIVQAHTTDQVMAVFREVEQAVSRGRHAAGYVAYEAAGGLNPELPRGT
CGDQPLIWFGIFRTRRPCDATTGAETNDGQTASPPELEISRQEYARALEKIREHIARGETYQVNFTTRQRFRVRGDQFAL
YRRLCRNQRAPFCAWLDTGSHRIISASPELFFSLKDRLLTMKPMKGTAPRHPLADDDQRRREELAASPKERAENLMIVDL
VRNDLSRIADIGSVAVPALFQVESYPTVHQMTSTVTARLKPEARLVDIFQALFPCGSVTGAPKRRTMEIIHDLERSPRGA
YCGAIGFVSPGGEATFSVAIRTAIVESTTGLGVMGIGSGITWDSNPEAEFRECLDKSAFLTGHAMDFGLIESLRWDAQGY
LLLERHLKRLEQSAARFGYPFSRRELLDRLVELERSLTGVHKVRVLLTSAGDLMLEQQEIDDTAAERPTLLVALASQRSD
PSDPLLYHKTTRRSRYDNELQARPECAEVILLNQRGELTEGCTTNLVLQRGEELLTPALHCGLLPGTLREELLQLGALRE
AILTPIDLETCDAFWLINSVRGWKKGQLLKNC
>Mature_592_residues
MHETVERLHPIALLESFSGGEFSRSYLFEDLETIVQAHTTDQVMAVFREVEQAVSRGRHAAGYVAYEAAGGLNPELPRGT
CGDQPLIWFGIFRTRRPCDATTGAETNDGQTASPPELEISRQEYARALEKIREHIARGETYQVNFTTRQRFRVRGDQFAL
YRRLCRNQRAPFCAWLDTGSHRIISASPELFFSLKDRLLTMKPMKGTAPRHPLADDDQRRREELAASPKERAENLMIVDL
VRNDLSRIADIGSVAVPALFQVESYPTVHQMTSTVTARLKPEARLVDIFQALFPCGSVTGAPKRRTMEIIHDLERSPRGA
YCGAIGFVSPGGEATFSVAIRTAIVESTTGLGVMGIGSGITWDSNPEAEFRECLDKSAFLTGHAMDFGLIESLRWDAQGY
LLLERHLKRLEQSAARFGYPFSRRELLDRLVELERSLTGVHKVRVLLTSAGDLMLEQQEIDDTAAERPTLLVALASQRSD
PSDPLLYHKTTRRSRYDNELQARPECAEVILLNQRGELTEGCTTNLVLQRGEELLTPALHCGLLPGTLREELLQLGALRE
AILTPIDLETCDAFWLINSVRGWKKGQLLKNC

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=258, Percent_Identity=42.6356589147287, Blast_Score=211, Evalue=8e-56,
Organism=Escherichia coli, GI1787518, Length=271, Percent_Identity=31.3653136531365, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320935, Length=264, Percent_Identity=33.3333333333333, Blast_Score=153, Evalue=8e-38,
Organism=Saccharomyces cerevisiae, GI6324361, Length=284, Percent_Identity=27.112676056338, Blast_Score=112, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 66318; Mature: 66318

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHETVERLHPIALLESFSGGEFSRSYLFEDLETIVQAHTTDQVMAVFREVEQAVSRGRHA
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
AGYVAYEAAGGLNPELPRGTCGDQPLIWFGIFRTRRPCDATTGAETNDGQTASPPELEIS
CCEEEEECCCCCCCCCCCCCCCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCEEC
RQEYARALEKIREHIARGETYQVNFTTRQRFRVRGDQFALYRRLCRNQRAPFCAWLDTGS
HHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCC
HRIISASPELFFSLKDRLLTMKPMKGTAPRHPLADDDQRRREELAASPKERAENLMIVDL
CEEEECCHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCEEEHHH
VRNDLSRIADIGSVAVPALFQVESYPTVHQMTSTVTARLKPEARLVDIFQALFPCGSVTG
HHHHHHHHHHHCHHHHHHHHEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
APKRRTMEIIHDLERSPRGAYCGAIGFVSPGGEATFSVAIRTAIVESTTGLGVMGIGSGI
CCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHCCCCCEEEECCCCC
TWDSNPEAEFRECLDKSAFLTGHAMDFGLIESLRWDAQGYLLLERHLKRLEQSAARFGYP
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
FSRRELLDRLVELERSLTGVHKVRVLLTSAGDLMLEQQEIDDTAAERPTLLVALASQRSD
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHHHCHHHHCCCEEEEEEECCCCC
PSDPLLYHKTTRRSRYDNELQARPECAEVILLNQRGELTEGCTTNLVLQRGEELLTPALH
CCCCEEEECHHHHHHCCCHHHCCCCHHHEEEECCCCCCCCCCHHHHHHHCCHHHHHHHHH
CGLLPGTLREELLQLGALREAILTPIDLETCDAFWLINSVRGWKKGQLLKNC
HCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHCC
>Mature Secondary Structure
MHETVERLHPIALLESFSGGEFSRSYLFEDLETIVQAHTTDQVMAVFREVEQAVSRGRHA
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
AGYVAYEAAGGLNPELPRGTCGDQPLIWFGIFRTRRPCDATTGAETNDGQTASPPELEIS
CCEEEEECCCCCCCCCCCCCCCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCEEC
RQEYARALEKIREHIARGETYQVNFTTRQRFRVRGDQFALYRRLCRNQRAPFCAWLDTGS
HHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCC
HRIISASPELFFSLKDRLLTMKPMKGTAPRHPLADDDQRRREELAASPKERAENLMIVDL
CEEEECCHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCEEEHHH
VRNDLSRIADIGSVAVPALFQVESYPTVHQMTSTVTARLKPEARLVDIFQALFPCGSVTG
HHHHHHHHHHHCHHHHHHHHEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
APKRRTMEIIHDLERSPRGAYCGAIGFVSPGGEATFSVAIRTAIVESTTGLGVMGIGSGI
CCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHCCCCCEEEECCCCC
TWDSNPEAEFRECLDKSAFLTGHAMDFGLIESLRWDAQGYLLLERHLKRLEQSAARFGYP
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
FSRRELLDRLVELERSLTGVHKVRVLLTSAGDLMLEQQEIDDTAAERPTLLVALASQRSD
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHHHCHHHHCCCEEEEEEECCCCC
PSDPLLYHKTTRRSRYDNELQARPECAEVILLNQRGELTEGCTTNLVLQRGEELLTPALH
CCCCEEEECHHHHHHCCCHHHCCCCHHHEEEECCCCCCCCCCHHHHHHHCCHHHHHHHHH
CGLLPGTLREELLQLGALREAILTPIDLETCDAFWLINSVRGWKKGQLLKNC
HCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]